Gene

KWMTBOMO04441  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA005380

Annotation

PREDICTED:_venom_protease-like_[Bombyx_mori]

Location

Bomo_Chr8(-):6722624-6736932      View in EpiBrowser

Location in the cell

Extracellular   Reliability : 1.393

CDS

ATGAGGCAATATGGTCCTAAGCATTTAATATGGATATTAATTATATCCGGCATTCTTATAAAAGCCGAAGACGTTGGAGATGAATGCACCCCAAATAACCAGATATCTGAAGGTATCTGTACTCTGGTGAATGATTGTCCTCAGGCTGTAATGGCAATAAAAAATAAAAGGTTTCAACCATTTCAAAGATGTGGATTCAGAGGATTTCAGGAGATAGTTTGTTGCCCTACAACTGTGGACAAATTTGGTCAAACAGAGAAAACAAGAACTATTAAACGAATTGCTGAACGAGAATGTGACAAAATCATATCTTCAACTGTACCTCCGCTCGACCTGTATATACTTGGCGGGGAAGCTGCATCGATGGGAGAATTTCCTTACATGGTTGCTGTTGGCTTCGACCGTGGTAATGGTTACGAATTCGATTGCGGAGGTTCGTTGCTATCCAACCTGTATGTACTGACAGCTGCGCACTGCGTCGACACATTGGATCGGATAGAGCCCAGTTTGGTGCGCGTCGGTGTTATAGAGCTGGGCAGCAACGCTTGGACCGAGGGCACGGACTACCGCATCGCGCAAATCATAACCCACCCGAATTACACCAGACGAGAGAAATACCATGACTTGGCCTTACTCAGGTTGGAAAAAGCAGTCGCATTCTCGAGCAACGTAAATGCTGTGTGTTTGGAAACGAGTACAGAAGATCCAACTGTTCCATTGACCATCACCGGTTGGGGGAAGATAAGTAATACTAGGAACGCTAAAAGCAATATATTACTCAAGGCGAATGTGACCGCTGTAAAGGCTGAGAAGTGTAGTGAATCCTACCTGAATTGGCGTAAACTACCTAAAGGCATATCCGACAGTCAGATTTGTGCTGGAGATCCTGAAGGCATCAGGGATACTTGTCAGGGCGACTCGGGCGGTCCGCTGCAGATGTGGCGCGACGTGTACCGGCTAGTCGGCGTGACGTCATTCGGGCGCGGCTGCGGCTCGCCCGTGCCCGGCGTGTACACGCGCCTGTCGCGCTACCTCGACTGGATCGAATCTGTCGTATGGCCCAATCACGTTTAA

Protein

MRQYGPKHLIWILIISGILIKAEDVGDECTPNNQISEGICTLVNDCPQAVMAIKNKRFQPFQRCGFRGFQEIVCCPTTVDKFGQTEKTRTIKRIAERECDKIISSTVPPLDLYILGGEAASMGEFPYMVAVGFDRGNGYEFDCGGSLLSNLYVLTAAHCVDTLDRIEPSLVRVGVIELGSNAWTEGTDYRIAQIITHPNYTRREKYHDLALLRLEKAVAFSSNVNAVCLETSTEDPTVPLTITGWGKISNTRNAKSNILLKANVTAVKAEKCSESYLNWRKLPKGISDSQICAGDPEGIRDTCQGDSGGPLQMWRDVYRLVGVTSFGRGCGSPVPGVYTRLSRYLDWIESVVWPNHV

Similarity

Belongs to the peptidase S1 family.

Uniprot

A0A290U6G2   A0A1E1WR09   Q5MPC8   A0A2H1WH67   A0A194PXG1   S4PBS4   + More
A0A191XQK8   A0A212FEM3   A0A194RCA3   A0A3S2M5Y0   A0A212FFV4   A0A034VK88   A0A0K8TZ88   A0A1V1FKN1   A0A1Y1ND16   A0A1W4WG82   D6WV12   A0A2J7QCI9   T1PLT8   W8BWP2   A0A2P8XRL8   A0A1Q3FGD5   A0A0T6AT77   B0X814   Q9XY63   A0A1J1INC2   A0A182M4M7   A0A2M4BSS9   A0A182UFN5   A7USI2   W5JTH3   A0A2C9GS33   A0A182KF51   A0A2M4AVR2   A0A182VBQ0   A0A2M4AVR1   A0A0K8VST9   T1E9T1   A0A0A1XH26   A0A034WJS9   A0A182J5D5   A0A084VFL8   A0A2M4BUS3   A0A182PZZ7   A0A0L7R7Y2   B3MWJ3   Q17CN4   A0A195CK42   A0A026WZH2   T1PES6   A0A1I8NHA9   A0A1I8NHA4   D3TMC3   A0A3L8DCB2   E2ARP5   A0A1A9Y007   A0A026WCC0   A0A0M9AB69   Q171M7   A0A1Y1N017   A0A0P6ISZ8   A0A088ATI0   W8C4A8   A0A348G5Y6   D6WCU1   A0A1W6EW85   A0A2A3EIB4   A0A195EVD6   F4X254   A0A1S4FH91   A0A2M4DQF4   A0A1Y1KPC1   J9HYX9   Q16NE9   A0A0A1XND1   N6TSF6   A0A0A1WWW1   A0A182VFE5   A0A182KNG1   Q5TNC5   W5JRY9   A0A2M4AP36   A0A1I8P9N3   A0A1B0D6M3   A0A1B0FMC8   A0A0P6IUV8   A0A182X8T2   A0A1S4FGZ3   B0W6K2   A0A0A1XBJ5   A0A023ESS7   A0A182RV45  

Pubmed

28953952    15944088    26354079    23622113    22118469    25348373    + More
28410430    28004739    18362917    19820115    24495485    29403074    12364791    14747013    17210077    20920257    23761445    25830018    24438588    17994087    18057021    17510324    24508170    25315136    20353571    30249741    20798317    26999592    21719571    23537049    20966253    24945155   

EMBL

KY680240    ATD13321.1    GDQN01001650    JAT89404.1    AY672782    AAV91004.1    + More
ODYU01008646    SOQ52408.1    KQ459589    KPI97708.1    GAIX01004461    JAA88099.1    KU360127    ANJ42865.1    AGBW02008921    OWR52184.1    KQ460397    KPJ15232.1    RSAL01000025    RVE52129.1    AGBW02008764    OWR52603.1    GAKP01016974    GAKP01016970    JAC41978.1    GDHF01032716    GDHF01010346    JAI19598.1    JAI41968.1    FX985359    BAX07372.1    GEZM01008423    JAV94790.1    KQ971357    EFA09207.2    NEVH01016289    PNF26300.1    KA649747    AFP64376.1    GAMC01005232    JAC01324.1    PYGN01001468    PSN34643.1    GFDL01008432    JAV26613.1    LJIG01022856    KRT78368.1    DS232472    EDS42283.1    AF053921    AAD21841.1    CVRI01000054    CRK99977.1    AXCM01000582    GGFJ01006840    MBW55981.1    AAAB01008846    EDO64345.2    ADMH02000122    ETN67672.1    APCN01001124    GGFK01011556    MBW44877.1    GGFK01011555    MBW44876.1    GDHF01028047    GDHF01010406    JAI24267.1    JAI41908.1    GAMD01001613    JAA99977.1    GBXI01004036    JAD10256.1    GAKP01003131    JAC55821.1    ATLV01012446    KE524793    KFB36762.1    GGFJ01007674    MBW56815.1    AXCN02002154    KQ414637    KOC66990.1    CH902625    EDV34978.2    KPU75377.1    CH477307    EAT44063.1    KQ977642    KYN01091.1    KK107077    EZA60544.1    KA647241    AFP61870.1    EZ422575    ADD18851.1    QOIP01000010    RLU17773.1    GL442157    EFN63907.1    KK107321    QOIP01000002    EZA52684.1    RLU25863.1    KQ435694    KOX80910.1    CH477450    EAT40694.2    GEZM01021578    JAV88927.1    GDUN01001005    JAN94914.1    GAMC01002402    JAC04154.1    FX985524    BBF97859.1    KQ971311    EEZ99357.2    KY563546    ARK19955.1    KZ288253    PBC30926.1    KQ981954    KYN32225.1    GL888565    EGI59470.1    GGFL01015607    MBW79785.1    GEZM01077598    JAV63253.1    EJY57695.1    CH477825    EAT35883.2    GBXI01001825    JAD12467.1    APGK01057050    KB741277    ENN71261.1    GBXI01011394    JAD02898.1    AAAB01008984    EAL38946.3    ADMH02000599    ETN65690.1    GGFK01009233    MBW42554.1    AJVK01012090    AJVK01012091    CCAG010000991    GDUN01001000    JAN94919.1    DS231848    EDS36676.1    GBXI01005976    JAD08316.1    GAPW01001752    JAC11846.1   

Proteomes

UP000053268    UP000007151    UP000053240    UP000283053    UP000192223    UP000007266    + More
UP000235965    UP000245037    UP000002320    UP000183832    UP000075883    UP000075902    UP000007062    UP000000673    UP000075840    UP000075881    UP000075903    UP000075880    UP000030765    UP000075886    UP000053825    UP000007801    UP000008820    UP000078542    UP000053097    UP000095301    UP000279307    UP000000311    UP000092443    UP000053105    UP000005203    UP000242457    UP000078541    UP000007755    UP000019118    UP000075882    UP000095300    UP000092462    UP000092444    UP000076407    UP000075900   

PRIDE

A0A088ATI0   

Pfam

PF00089   Trypsin        + More
PF12032   CLIP

Interpro

IPR018114   TRYPSIN_HIS        + More
IPR001254   Trypsin_dom       
IPR001314   Peptidase_S1A       
IPR009003   Peptidase_S1_PA       
IPR033116   TRYPSIN_SER       
IPR022700   CLIP       
IPR038565   CLIP_sf       

SUPFAM

SSF50494   SSF50494       

Gene 3D

2.20.20.90    

CDD

cd00190  Tryp_SPc

ProteinModelPortal

A0A290U6G2   A0A1E1WR09   Q5MPC8   A0A2H1WH67   A0A194PXG1   S4PBS4   + More
A0A191XQK8   A0A212FEM3   A0A194RCA3   A0A3S2M5Y0   A0A212FFV4   A0A034VK88   A0A0K8TZ88   A0A1V1FKN1   A0A1Y1ND16   A0A1W4WG82   D6WV12   A0A2J7QCI9   T1PLT8   W8BWP2   A0A2P8XRL8   A0A1Q3FGD5   A0A0T6AT77   B0X814   Q9XY63   A0A1J1INC2   A0A182M4M7   A0A2M4BSS9   A0A182UFN5   A7USI2   W5JTH3   A0A2C9GS33   A0A182KF51   A0A2M4AVR2   A0A182VBQ0   A0A2M4AVR1   A0A0K8VST9   T1E9T1   A0A0A1XH26   A0A034WJS9   A0A182J5D5   A0A084VFL8   A0A2M4BUS3   A0A182PZZ7   A0A0L7R7Y2   B3MWJ3   Q17CN4   A0A195CK42   A0A026WZH2   T1PES6   A0A1I8NHA9   A0A1I8NHA4   D3TMC3   A0A3L8DCB2   E2ARP5   A0A1A9Y007   A0A026WCC0   A0A0M9AB69   Q171M7   A0A1Y1N017   A0A0P6ISZ8   A0A088ATI0   W8C4A8   A0A348G5Y6   D6WCU1   A0A1W6EW85   A0A2A3EIB4   A0A195EVD6   F4X254   A0A1S4FH91   A0A2M4DQF4   A0A1Y1KPC1   J9HYX9   Q16NE9   A0A0A1XND1   N6TSF6   A0A0A1WWW1   A0A182VFE5   A0A182KNG1   Q5TNC5   W5JRY9   A0A2M4AP36   A0A1I8P9N3   A0A1B0D6M3   A0A1B0FMC8   A0A0P6IUV8   A0A182X8T2   A0A1S4FGZ3   B0W6K2   A0A0A1XBJ5   A0A023ESS7   A0A182RV45  

PDB

6O1G     E-value=3.55988e-35,     Score=371

KEGG

101742608    K20671 serine protease persephone [EC:3.4.21.-] | (RefSeq) venom protease-like

PATHWAY

04624    Toll and Imd signaling pathway - Bombyx mori (domestic silkworm)

GO

GO:0004252   GO:0016021   GO:0008236   GO:0006508   GO:0005524   GO:0005737   GO:0006434   GO:0004812   GO:0006418   GO:0009058   GO:0016742   GO:0003824  

SignalP

Position:   1 - 22,         Likelihood:  0.994993

 

 

Length:

357

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0583

Exp number, first 60 AAs:

0.03947

Total prob of N-in:

0.01749

outside

1  -  357

 

 

Pi

224.419146

Theta

188.495587

Tajima's D

0.287996

CLR

0.245532

CSRT

0.450027498625069

Interpretation

Possibly Positive selection