Gene

KWMTBOMO04437  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA005384

Annotation

PREDICTED:_TP53-regulated_inhibitor_of_apoptosis_1-like_[Amyelois_transitella]

Location

Bomo_Chr8(-):6697546-6698302      View in EpiBrowser

Full name

Mediator of RNA polymerase II transcription subunit 10      

Alternative Name

Mediator complex subunit 10

Location in the cell

Nuclear   Reliability : 3.099

CDS

ATGAACAGCATTGGCGAAGAATGTACAGACCTAAAGAAAAAATACGATGATTGTTTCAATACTTGGTTCTCGGAAAGGTTCTTAAAAGGCGATCAAGATGATTCTGTTTGCGCTGGAATATTTAAAATTTATCAAGAATGTGTTAAGAATGCAATGAAACAGCAAAGCATTGATTTCAAAGAAATAGATAAGGATATCTTAGGCACTGAAAATGAATACAAAACACCACCAAATGCAAATAGTAGCTGA

Protein

MNSIGEECTDLKKKYDDCFNTWFSERFLKGDQDDSVCAGIFKIYQECVKNAMKQQSIDFKEIDKDILGTENEYKTPPNANSS

Description

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Subunit

Component of the Mediator complex.

Similarity

Belongs to the Mediator complex subunit 10 family.

Uniprot

H9J792   A0A2H1WNZ7   A0A194RCB4   I4DKY8   S4Q073   A0A212FFV1   + More
A0A3S2P4H5   A0A182GP47   A0A1Q3F0L2   Q16UY0   B0WF55   A0A182KES1   A0A182VXN4   A0A182PF21   A0A182RJ58   A0A182YIF1   A0A0K8TRU6   A0A1C7CZ52   A0A182UZV5   A0A182XH53   Q7Q279   A0A182I899   A0A1W4XEP7   A0A139W968   A0A067R3T0   A0A2P8XJQ0   A0A1B0D3F1   A0A336KNR2   R4UJ96   A0A084W5B8   A0A1L8DJN6   A0A182QIW9   A0A182N6G2   A0A2M4C5F2   A0A182F836   A0A0L0BNQ7   A0A2M3ZKH6   A0A2M4B086   E9HGQ9   A0A0M4EAB1   A0A1D2MYN1   W5J612   E2AEI4   A0A293M5G3   G3MP28   A0A1I8M0Y7   B4LNA2   A0A131XRG5   B4KMZ9   A0A1L8DJM4   A0A023FG95   A0A224ZAR7   A0A0C9SBI2   A0A1E1WZ34   A0A0J7P0L0   B4J788   B4GIB0   A0A023FVW9   B3MIF0   A0A1L8ED43   A0A1B0FHY4   A0A1I8P407   F4WJ98   A0A131YGL8   A0A1A9UI94   A0A165ACG2   Q28Z42   A0A2R5LGE6   A0A3L8DAD6   A0A3B0J5K1   A0A1A9YCY1   A0A1B0BRW1   B7PKG1   A0A1W4VCY1   A0A232F8S2   A0A1W4V0M0   B4MRZ6   A0A1S3CUA6   B4HMY5   B4P561   B4QBB8   A0A0K8REP8   B3NML2   B4P560   Q6NLJ9   A1ZAX2   B4QBB7   A0A224Y4W7   B3NML1   B4HMY4   E2BLQ8   R4G3Y5   A0A1L8EAS1   K1QAU6   A0A1B6KTB8   A0A2B4SV13   C3XVM0   A0A0L8HTE4   A0A077Z0A0   A0A023FAL9  

Pubmed

19121390    26354079    22651552    23622113    22118469    26483478    + More
17510324    25244985    26369729    20966253    12364791    14747013    17210077    18362917    19820115    24845553    29403074    24438588    26108605    21292972    27289101    20920257    23761445    20798317    22216098    25315136    17994087    28049606    28797301    26131772    28503490    21719571    26830274    15632085    30249741    28648823    17550304    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    22992520    18563158    25474469   

EMBL

BABH01013633    ODYU01010002    SOQ54795.1    KQ460397    KPJ15242.1    AK401956    + More
KQ459589    BAM18578.1    KPI97700.1    GAIX01000288    JAA92272.1    AGBW02008764    OWR52607.1    RSAL01000025    RVE52136.1    JXUM01074125    JXUM01077789    KQ563027    KQ562813    KXJ74618.1    KXJ75077.1    GFDL01013953    JAV21092.1    CH477610    EAT38339.1    DS231914    EDS26000.1    GDAI01000735    JAI16868.1    AAAB01008978    EAA13625.3    APCN01002684    KQ972625    KXZ75834.1    KK853008    KDR12557.1    PYGN01001907    PSN32220.1    AJVK01023516    UFQS01000643    UFQS01001157    UFQT01000643    UFQT01001157    SSX05682.1    SSX09289.1    SSX26041.1    KC632310    AGM32124.1    ATLV01020573    KE525303    KFB45412.1    GFDF01007530    JAV06554.1    AXCN02000286    GGFJ01011240    MBW60381.1    JRES01001589    KNC21687.1    GGFM01008241    MBW28992.1    GGFK01013128    MBW46449.1    GL732643    EFX69007.1    CP012524    ALC41971.1    LJIJ01000382    ODM98092.1    ADMH02002112    ETN58838.1    GL438862    EFN68141.1    GFWV01010559    MAA35288.1    JO843629    JO843630    AEO35246.1    CH940648    EDW61054.2    GEFH01000430    JAP68151.1    CH933808    EDW09921.1    GFDF01007534    JAV06550.1    GBBK01004483    JAC19999.1    GFPF01012848    MAA23994.1    GBZX01002947    JAG89793.1    GFAC01006946    JAT92242.1    LBMM01000514    KMQ98165.1    CH916367    EDW02106.1    CH479183    EDW36230.1    GBBL01002422    JAC24898.1    CH902619    EDV36998.1    GFDG01002139    JAV16660.1    CCAG010015795    GL888182    EGI65676.1    GEDV01010892    JAP77665.1    LRGB01000626    KZS17449.1    CM000071    EAL25773.1    GGLE01004413    MBY08539.1    QOIP01000010    RLU17470.1    OUUW01000001    SPP75053.1    JXJN01019359    ABJB010811916    DS733176    EEC07083.1    NNAY01000645    OXU27216.1    CH963850    EDW74885.1    CH480816    EDW48335.1    CM000158    EDW91762.1    CM000362    CM002911    EDX07542.1    KMY94646.1    GADI01004201    JAA69607.1    CH954179    EDV54951.1    EDW91761.1    AE013599    BT012332    KX671585    AAM68484.1    AAS77457.1    AOG29610.1    AAM68483.2    EDX07541.1    KMY94645.1    GFTR01000897    JAW15529.1    EDV54950.1    EDW48334.1    GL449036    EFN83392.1    ACPB03016348    GAHY01001261    JAA76249.1    GFDG01003077    JAV15722.1    JH819063    EKC25955.1    GEBQ01025300    JAT14677.1    LSMT01000009    PFX33721.1    GG666469    EEN67813.1    KQ417319    KOF92486.1    HG805814    CDW52045.1    GBBI01000759    JAC17953.1   

Proteomes

UP000005204    UP000053240    UP000053268    UP000007151    UP000283053    UP000069940    + More
UP000249989    UP000008820    UP000002320    UP000075881    UP000075920    UP000075885    UP000075900    UP000076408    UP000075882    UP000075903    UP000076407    UP000007062    UP000075840    UP000192223    UP000007266    UP000027135    UP000245037    UP000092462    UP000030765    UP000075886    UP000075884    UP000069272    UP000037069    UP000000305    UP000092553    UP000094527    UP000000673    UP000000311    UP000095301    UP000008792    UP000009192    UP000036403    UP000001070    UP000008744    UP000007801    UP000092444    UP000095300    UP000007755    UP000078200    UP000076858    UP000001819    UP000279307    UP000268350    UP000092443    UP000092460    UP000001555    UP000192221    UP000215335    UP000007798    UP000079169    UP000001292    UP000002282    UP000000304    UP000008711    UP000000803    UP000008237    UP000015103    UP000005408    UP000225706    UP000001554    UP000053454    UP000030665   

PRIDE

H9J792    Q6NLJ9    A1ZAX2   

Pfam

PF05254   UPF0203        + More
PF09748   Med10

Interpro

IPR007918   MDM35_apoptosis        + More
IPR035897   Toll_tir_struct_dom_sf       
IPR019145   Mediator_Med10       

Gene 3D

3.40.50.10140    

ProteinModelPortal

H9J792   A0A2H1WNZ7   A0A194RCB4   I4DKY8   S4Q073   A0A212FFV1   + More
A0A3S2P4H5   A0A182GP47   A0A1Q3F0L2   Q16UY0   B0WF55   A0A182KES1   A0A182VXN4   A0A182PF21   A0A182RJ58   A0A182YIF1   A0A0K8TRU6   A0A1C7CZ52   A0A182UZV5   A0A182XH53   Q7Q279   A0A182I899   A0A1W4XEP7   A0A139W968   A0A067R3T0   A0A2P8XJQ0   A0A1B0D3F1   A0A336KNR2   R4UJ96   A0A084W5B8   A0A1L8DJN6   A0A182QIW9   A0A182N6G2   A0A2M4C5F2   A0A182F836   A0A0L0BNQ7   A0A2M3ZKH6   A0A2M4B086   E9HGQ9   A0A0M4EAB1   A0A1D2MYN1   W5J612   E2AEI4   A0A293M5G3   G3MP28   A0A1I8M0Y7   B4LNA2   A0A131XRG5   B4KMZ9   A0A1L8DJM4   A0A023FG95   A0A224ZAR7   A0A0C9SBI2   A0A1E1WZ34   A0A0J7P0L0   B4J788   B4GIB0   A0A023FVW9   B3MIF0   A0A1L8ED43   A0A1B0FHY4   A0A1I8P407   F4WJ98   A0A131YGL8   A0A1A9UI94   A0A165ACG2   Q28Z42   A0A2R5LGE6   A0A3L8DAD6   A0A3B0J5K1   A0A1A9YCY1   A0A1B0BRW1   B7PKG1   A0A1W4VCY1   A0A232F8S2   A0A1W4V0M0   B4MRZ6   A0A1S3CUA6   B4HMY5   B4P561   B4QBB8   A0A0K8REP8   B3NML2   B4P560   Q6NLJ9   A1ZAX2   B4QBB7   A0A224Y4W7   B3NML1   B4HMY4   E2BLQ8   R4G3Y5   A0A1L8EAS1   K1QAU6   A0A1B6KTB8   A0A2B4SV13   C3XVM0   A0A0L8HTE4   A0A077Z0A0   A0A023FAL9  

PDB

6I4Y     E-value=2.14831e-15,     Score=194

KEGG

101743048    K17968 TRIAP1/MDM35 family protein | (RefSeq) TP53-regulated inhibitor of apoptosis 1-like

GO

GO:0016592   GO:0006357   GO:0003712  

Subcellular location

Nucleus  

Length:

82

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0

Exp number, first 60 AAs:

0

Total prob of N-in:

0.32659

outside

1  -  82

 

 

Pi

177.484449

Theta

158.925235

Tajima's D

0.383527

CLR

41.256297

CSRT

0.479126043697815

Interpretation

Uncertain