Gene

KWMTBOMO04433

Pre Gene Modal

BGIBMGA005387

Annotation

PREDICTED:_arf-GAP_with_coiled-coil?_ANK_repeat_and_PH_domain-containing_protein_2_[Bombyx_mori]

Location

Bomo_Chr8(-):6653028-6656962      View in EpiBrowser

Full name

Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2      

Alternative Name

Centaurin-beta-2

Location in the cell

Extracellular   Reliability : 2.071 Nuclear   Reliability : 1.824

CDS

ATGGCGTGCTCGTTCCTGTTGCTGAACGGAAGCAAGCTGAACGTGCAAGATGAAGATGGGAAGACTCCCTTGCATCTCGCCACGGAAGCAGGACACACCGGACAGGTTTGCCTTCTCCTGCGGTATCGCGCCGACCAATCGATACGTGACAAGGACGGACGATCACCGCTCGACATCGCCGTGGAACACGCCAACGCCGATATTGTTACTCTGCTACGGCTGACGAAGCTGAACGAGGAGATGCGCGAGAGCGAGATGAGCTCTAACGACGACACGTACAACGAGGTGTTCCGCGACTACACGCAGCTCGCGCACTCGCACCCCGAGCGGCTCGTGCGCGCCCGCAACAACAACTGCGAACACAACAGTGAGCAGTCGACTGAATGA

Protein

MACSFLLLNGSKLNVQDEDGKTPLHLATEAGHTGQVCLLLRYRADQSIRDKDGRSPLDIAVEHANADIVTLLRLTKLNEEMRESEMSSNDDTYNEVFRDYTQLAHSHPERLVRARNNNCEHNSEQSTE

Description

GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6).

Keywords

ANK repeat   Coiled coil   Complete proteome   Endosome   GTPase activation   Membrane   Metal-binding   Reference proteome   Repeat   Zinc   Zinc-finger  

Feature

chain  Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2

Uniprot

H9J795   A0A2H1WPQ6   A0A3S2TQ84   A0A194RH36   A0A194PY68   A0A2A4J2N2   + More
A0A212EZU5   A0A1B6D8H8   A0A2P8YQI4   A0A0N0BDV5   E0W416   A0A154PSJ2   A0A0L7R3V4   A0A1B6HUA7   A0A0J7L2Q0   A0A026VW25   F4WSP8   A0A195FJ28   A0A151I1C4   A0A158NDC8   A0A151XHS4   U4TZ47   A0A1Y1L0G4   E9IVA0   A0A0C9RAI7   A0A195DIU9   A0A2A3EAS8   A0A088AQD7   N6SY22   E2C8T5   A0A1B6JJY1   A0A023F1X2   A0A1B6L5C8   A0A1B6LAQ4   T1HYS0   A0A1B6G7X6   D6X007   A0A224XK51   T1JJI0   A0A210QD91   A0A2C9L0C4   A0A2C9L030   A0A2C9L087   A0A2C9KZY6   A0A1W4XCI4   A0A087VNY6   K9KED4   A0A0B8RV23   A0A1W7RJB4   A0A0K8S2P1   T1E6H6   J3SE08   A0A0K8RZ83   A0A098LZ99   A0A091HAA6   A0A1L8DLQ1   C3ZIA5   A0A0A9YW47   A0A094LQ08   A0A3P9M1I1   A0A1B0GI65   A0A094LDS2   A0A1V4K3U3   U3F977   A0A091N3N3   A0A093QDY4   U3IB16   R0LHM2   A0A093BVZ2   A0A091QLK1   R7VPU4   A0A091PWI7   A0A091NPR4   A0A1S3DKS5   A0A146LN58   A0A2I0UNI6   A0A091VHF5   U3JXK6   A0A093IQN0   G1N552   A0A0A0AEW6   A0A091VCX5   A0A093ERC5   A0A091QAV1   H0ZFH1   A0A091GBA7   A0A087R7X0   A0A093CG13   A0A091L041   A0A2K6DUV5   A0A2K5X414   A0A2K5QWV3   A0A091TXH4   A0A3M0JSP1   Q5ZK62   A0A2K6G8X6   A0A2K6MRH3   A0A2K5I6E2   L7MLR8   A0A091J6T3  

Pubmed

19121390    26354079    22118469    29403074    20566863    24508170    + More
30249741    21719571    21347285    23537049    28004739    21282665    20798317    25474469    18362917    19820115    28812685    15562597    25476704    26358130    25727380    23758969    23025625    18563158    25401762    17554307    23915248    23749191    23371554    26823975    20838655    20360741    15642098    25576852   

EMBL

BABH01013628    ODYU01010125    SOQ55018.1    RSAL01000025    RVE52140.1    KQ460397    + More
KPJ15246.1    KQ459589    KPI97694.1    NWSH01003543    PCG66129.1    AGBW02011227    OWR47002.1    GEDC01015317    JAS21981.1    PYGN01000431    PSN46505.1    KQ435855    KOX70664.1    DS235886    EEB20372.1    KQ435036    KZC14080.1    KQ414661    KOC65557.1    GECU01032828    GECU01029454    JAS74878.1    JAS78252.1    LBMM01001089    KMQ96943.1    KK107737    QOIP01000013    EZA47962.1    RLU15490.1    GL888326    EGI62791.1    KQ981560    KYN39989.1    KQ976599    KYM79511.1    ADTU01012601    KQ982130    KYQ59838.1    KB631874    ERL86864.1    GEZM01068131    JAV67159.1    GL766194    EFZ15490.1    GBYB01013474    JAG83241.1    KQ980800    KYN12813.1    KZ288317    PBC28296.1    APGK01052697    KB741213    ENN72674.1    GL453694    EFN75652.1    GECU01008110    JAS99596.1    GBBI01003170    JAC15542.1    GEBQ01021045    JAT18932.1    GEBQ01019188    JAT20789.1    ACPB03018499    GECZ01011213    JAS58556.1    KQ971372    EFA10505.1    GFTR01007903    JAW08523.1    JH430738    NEDP02004099    OWF46700.1    KL500354    KFO14328.1    JL640610    AEQ00849.1    GBSH01000333    JAG68691.1    GDAY02000193    JAV51220.1    GBKD01000179    JAG47439.1    GAAZ01000205    JAA97738.1    JU173920    GBEX01000268    AFJ49446.1    JAI14292.1    GBKC01000280    JAG45790.1    GBSI01001206    JAC95290.1    KL504548    KFO84358.1    GFDF01006691    JAV07393.1    GG666627    EEN47630.1    GBHO01009824    GBHO01009823    JAG33780.1    JAG33781.1    KL361522    KFZ65739.1    AJWK01011394    AJWK01011395    AJWK01011396    AJWK01011397    AJWK01011398    KL266572    KFZ62129.1    LSYS01004732    OPJ79064.1    GAEP01000159    JAB54662.1    KK841653    KFP84036.1    KL418819    KFW87138.1    ADON01036965    ADON01036966    KB742711    EOB05194.1    KL228588    KFV04132.1    KK701382    KFQ27486.1    KB375824    EMC80821.1    KK666488    KFQ11701.1    KL391390    KFP91733.1    GDHC01010407    JAQ08222.1    KZ505674    PKU47615.1    KK431148    KFQ89048.1    AGTO01010284    KK592435    KFW01029.1    KL871360    KGL91988.1    KL410876    KFR00620.1    KK369788    KFV42953.1    KK690858    KFQ16588.1    ABQF01023637    KL448052    KFO79655.1    KL226192    KFM09574.1    KL458979    KFV11267.1    KK761107    KFP44955.1    AQIA01037269    AQIA01037270    AQIA01037271    AQIA01037272    AQIA01037273    AQIA01037274    AQIA01037275    AQIA01037276    KK466670    KFQ82250.1    QRBI01000134    RMC02114.1    AJ720222    CAG31881.1    GACK01000801    JAA64233.1    KK501618    KFP16709.1   

Proteomes

UP000005204    UP000283053    UP000053240    UP000053268    UP000218220    UP000007151    + More
UP000245037    UP000053105    UP000009046    UP000076502    UP000053825    UP000036403    UP000053097    UP000279307    UP000007755    UP000078541    UP000078540    UP000005205    UP000075809    UP000030742    UP000078492    UP000242457    UP000005203    UP000019118    UP000008237    UP000015103    UP000007266    UP000242188    UP000076420    UP000192223    UP000001554    UP000265180    UP000092461    UP000190648    UP000016666    UP000079169    UP000016665    UP000001645    UP000053858    UP000053283    UP000007754    UP000053760    UP000053286    UP000233120    UP000233100    UP000233040    UP000269221    UP000000539    UP000233160    UP000233180    UP000233080    UP000053119   

PRIDE

H9J795    Q5ZK62   

Pfam

PF12796   Ank_2        + More
PF01412   ArfGap
PF00169   PH
PF03151   TPT
PF07522   DRMBL

Interpro

IPR002110   Ankyrin_rpt        + More
IPR020683   Ankyrin_rpt-contain_dom       
IPR036770   Ankyrin_rpt-contain_sf       
IPR038508   ArfGAP_dom_sf       
IPR001164   ArfGAP_dom       
IPR027267   AH/BAR_dom_sf       
IPR037278   ARFGAP/RecO       
IPR011993   PH-like_dom_sf       
IPR001849   PH_domain       
IPR038584   L33_sf       
IPR004853   Sugar_P_trans_dom       
IPR036866   RibonucZ/Hydroxyglut_hydro       
IPR011084   DRMBL       

SUPFAM

SSF48403   SSF48403        + More
SSF57863   SSF57863       
SSF103657   SSF103657       
SSF56281   SSF56281       

Gene 3D

1.25.40.20     1.20.1270.60     2.30.29.30     3.30.40.160     2.20.28.120     3.60.15.10    

CDD

cd00204  ANK

ProteinModelPortal

H9J795   A0A2H1WPQ6   A0A3S2TQ84   A0A194RH36   A0A194PY68   A0A2A4J2N2   + More
A0A212EZU5   A0A1B6D8H8   A0A2P8YQI4   A0A0N0BDV5   E0W416   A0A154PSJ2   A0A0L7R3V4   A0A1B6HUA7   A0A0J7L2Q0   A0A026VW25   F4WSP8   A0A195FJ28   A0A151I1C4   A0A158NDC8   A0A151XHS4   U4TZ47   A0A1Y1L0G4   E9IVA0   A0A0C9RAI7   A0A195DIU9   A0A2A3EAS8   A0A088AQD7   N6SY22   E2C8T5   A0A1B6JJY1   A0A023F1X2   A0A1B6L5C8   A0A1B6LAQ4   T1HYS0   A0A1B6G7X6   D6X007   A0A224XK51   T1JJI0   A0A210QD91   A0A2C9L0C4   A0A2C9L030   A0A2C9L087   A0A2C9KZY6   A0A1W4XCI4   A0A087VNY6   K9KED4   A0A0B8RV23   A0A1W7RJB4   A0A0K8S2P1   T1E6H6   J3SE08   A0A0K8RZ83   A0A098LZ99   A0A091HAA6   A0A1L8DLQ1   C3ZIA5   A0A0A9YW47   A0A094LQ08   A0A3P9M1I1   A0A1B0GI65   A0A094LDS2   A0A1V4K3U3   U3F977   A0A091N3N3   A0A093QDY4   U3IB16   R0LHM2   A0A093BVZ2   A0A091QLK1   R7VPU4   A0A091PWI7   A0A091NPR4   A0A1S3DKS5   A0A146LN58   A0A2I0UNI6   A0A091VHF5   U3JXK6   A0A093IQN0   G1N552   A0A0A0AEW6   A0A091VCX5   A0A093ERC5   A0A091QAV1   H0ZFH1   A0A091GBA7   A0A087R7X0   A0A093CG13   A0A091L041   A0A2K6DUV5   A0A2K5X414   A0A2K5QWV3   A0A091TXH4   A0A3M0JSP1   Q5ZK62   A0A2K6G8X6   A0A2K6MRH3   A0A2K5I6E2   L7MLR8   A0A091J6T3  

PDB

6IF3     E-value=4.0823e-25,     Score=278

KEGG

101742418    K12489 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein | (RefSeq) arf-GAP with

GO

GO:0046872   GO:0005096   GO:0016021   GO:0080025   GO:0017137   GO:1990090   GO:0032456   GO:0010008   GO:0005515   GO:0003677   GO:0006355   GO:0016491   GO:0016638   GO:0004674   GO:0009058   GO:0016742   GO:0003824  

Subcellular location

Endosome membrane  

Length:

128

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00356

Exp number, first 60 AAs:

0.00356

Total prob of N-in:

0.02900

outside

1  -  128

 

 

Pi

242.409375

Theta

202.076902

Tajima's D

0.804774

CLR

0

CSRT

0.603969801509925

Interpretation

Possibly Positive selection