Gene

KWMTBOMO04429

Pre Gene Modal

BGIBMGA005390

Annotation

PREDICTED:_protein_hairy_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr8(-):6545218-6559422      View in EpiBrowser

Full name

Protein hairy      

Transcription factor

bHLH

Location in the cell

Nuclear   Reliability : 3.993

CDS

ATGGTGACTGGTATCGCTGGCAGCCCTCAACAGGGCGTATCCAACCCTGTCGTGGTGATGAACGCTGTCAATAATTCAGGACAAAATGATCAGAAAAAATCAAGTGATAATAGAAGGAGTAACAAGCCAATTATGGAGAAGAGACGTCGGGCGCGCATCAACAACTGTCTCAACGAGTTGAAAGCGCTGATCTTAGACGCGATGAAAAAAGATCCAGCTAGACATTCGAAGCTCGAAAAAGCCGACATATTAGAAATGACAGTGAAGCATCTAGAAGGTCTACGGTCAGAGGGTGCCGTTTCACCGGACAAGTTCCGGGCCGGCTATAGACAGTGCGTCACAGAGGTGGCAAAGTTCCAAGGCATGGAGCCTGCATTGCGGAGAAGGCTCGTCAGGCATTTGGAAACCTGCGTTAATAGCACTTCTGGAACAAGGCCTGCAAGTGCACCCACACCGCCTTCGGATACAGACGACCCCGGCAACCAACATTCCACAATTTTCATTGCTGCGGGTCCCGGTTCCGGTGTGCGTTTGCTGCCAACACGTCTCTCTAACGGCGATATAGCTTTAGTGTTGCCCGCGGGTGTGACGACTAGCGCTATAGGGGGGCTACCCAACTTAGTGCCGCTGTCACCAAGAGATGCATCGTCTTCAACATCAGAACAGAGATGCTACTCGCCCGAGAGTTCTGGTTGGGGAACACCCCCTCCTTCCTCGGAGGATGCAGCACCTTTAGCATTAGTCACGAGAAAGCAGCCAGAAGAAAAACCCTGGAGGCCGTGGTGA

Protein

MVTGIAGSPQQGVSNPVVVMNAVNNSGQNDQKKSSDNRRSNKPIMEKRRRARINNCLNELKALILDAMKKDPARHSKLEKADILEMTVKHLEGLRSEGAVSPDKFRAGYRQCVTEVAKFQGMEPALRRRLVRHLETCVNSTSGTRPASAPTPPSDTDDPGNQHSTIFIAAGPGSGVRLLPTRLSNGDIALVLPAGVTTSAIGGLPNLVPLSPRDASSSTSEQRCYSPESSGWGTPPPSSEDAAPLALVTRKQPEEKPWRPW

Description

Pair-rule protein that regulates embryonic segmentation and adult bristle patterning. Transcriptional repressor of genes that require a bHLH protein for their transcription (e.g. ftz).

Subunit

Transcription repression requires formation of a complex with a corepressor protein (Groucho). Interacts with gro (via WPRW motif) and Topors.

Keywords

Complete proteome   Developmental protein   DNA-binding   Nucleus   Pair-rule protein   Polymorphism   Reference proteome   Repressor   Transcription   Transcription regulation   Ubl conjugation  

Feature

chain  Protein hairy

Uniprot

H9J798   A0A2H1WJX5   A0A2A4ISU6   A0A212EH70   A0A194Q2Q6   A0A194RCC4   + More
A0A0L7LBB9   D6X189   Q8T306   B5A7J9   A0A0F7II78   A0A0T6BBZ1   J9JVV3   A0A2H8TV71   A0A1W4XEE8   A0A336LPM3   A0A2S2R3K5   N6TQ44   A0A1J1J523   A0A1B6CL34   A0A023EQ79   A0A0C9REB0   A0A182GQD4   Q16NK4   U5EY94   A0A088A8V4   B0WDP0   A0A0L0CL81   A0A2A3EJJ6   A0A232EQZ9   A0A1Q3FI64   A0A0L7R3R9   A0A1Q3FI77   A0A067QJU3   A0A154PQ90   A0A182V0F6   B6EBG4   A0A1L8DG73   A0A1B6LLL5   A0A182X4S5   U4UEP8   A0A182N7Q8   A0A195F830   A0A182TSF6   A0A1B0C854   A0A182YNI9   A0A182I4S4   A0A182QTJ3   Q7Q509   E2C1B6   A0A182KNC7   T1DJS5   A0A195DKM5   A0A182WIC7   A0A195D7I2   K7J0Y2   A0A182PHT1   A0A182R2G0   A0A0J7L399   A0A195B2S5   A0A158NNH0   E2AUT4   A0A0M8ZTI6   A0A2H4N701   F4WQH7   A0A151WWM7   A0A2P6KEB2   A0A026VZJ9   B4PFK6   A0A1I8MJM2   B4HK14   Q95UA9   P14003   A0A1Z5KY33   A0A1W4USH5   A0A2R5LKL5  

Pubmed

19121390    22118469    26354079    26227816    18362917    19820115    + More
23537049    24945155    26483478    17510324    26108605    28648823    24845553    18927236    25244985    12364791    14747013    17210077    20798317    20966253    24330624    20075255    24599282    21347285    29084804    21719571    24508170    17994087    17550304    25315136    12242230    22936249    2479541    10731132    12537572    12537569    8001118    8649374    14871887    28528879   

EMBL

BABH01013618    ODYU01009153    SOQ53381.1    NWSH01008432    PCG62556.1    AGBW02014942    + More
OWR40837.1    KQ459589    KPI97690.1    KQ460397    KPJ15252.1    JTDY01001861    KOB72695.1    KQ971372    EFA10592.1    AJ457831    CAD29886.1    EU819553    ACF32779.1    KP147918    AKG92755.1    LJIG01002123    KRT84817.1    ABLF02018666    ABLF02018669    GFXV01005896    MBW17701.1    UFQT01000102    SSX20026.1    GGMS01015376    MBY84579.1    APGK01059138    KB741292    ENN70436.1    CVRI01000067    CRL06566.1    GEDC01023223    JAS14075.1    GAPW01002383    JAC11215.1    GBYB01011502    JAG81269.1    JXUM01080431    KQ563185    KXJ74312.1    CH477820    CH477344    EAT35935.1    EAT43027.1    GANO01000434    JAB59437.1    DS231899    EDS44739.1    JRES01000247    KNC33001.1    KZ288230    PBC31644.1    NNAY01002676    OXU20799.1    GFDL01007807    JAV27238.1    KQ414661    KOC65540.1    GFDL01007800    JAV27245.1    KK853387    KDR07936.1    KQ435036    KZC14071.1    FJ222592    ACI32659.1    GFDF01008709    JAV05375.1    GEBQ01015528    JAT24449.1    KB632056    ERL88375.1    KQ981744    KYN36214.1    AJWK01000187    APCN01002346    AXCN02000583    AAAB01008960    EAA11851.3    GL451914    EFN78278.1    GALA01000086    JAA94766.1    KQ980765    KYN13401.1    KQ976749    KYN08812.1    KC190514    AGF87125.1    LBMM01000869    KMQ97327.1    KQ976641    KYM78778.1    ADTU01021585    GL442888    EFN62809.1    KQ435855    KOX70647.1    MG437058    ATU89130.1    GL888273    EGI63577.1    KQ982691    KYQ52248.1    MWRG01014375    PRD24654.1    KK107535    EZA49218.1    CM000159    EDW93132.1    CH480815    EDW40750.1    AY055843    CM000363    CM002912    AAL17777.1    EDX09748.1    KMY98457.1    X15904    X15905    AY055833    AY055834    AY055835    AY055836    AY055837    AY055838    AY055839    AY055840    AY055841    AY055842    AE014296    AY119633    GFJQ02006938    JAW00032.1    GGLE01005849    MBY09975.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053268    UP000053240    UP000037510    + More
UP000007266    UP000007819    UP000192223    UP000019118    UP000183832    UP000069940    UP000249989    UP000008820    UP000005203    UP000002320    UP000037069    UP000242457    UP000215335    UP000053825    UP000027135    UP000076502    UP000075903    UP000076407    UP000030742    UP000075884    UP000078541    UP000075902    UP000092461    UP000076408    UP000075840    UP000075886    UP000007062    UP000008237    UP000075882    UP000078492    UP000075920    UP000078542    UP000002358    UP000075885    UP000075900    UP000036403    UP000078540    UP000005205    UP000000311    UP000053105    UP000007755    UP000075809    UP000053097    UP000002282    UP000095301    UP000001292    UP000000304    UP000000803    UP000192221   

PRIDE

H9J798    P14003   

Pfam

PF07527   Hairy_orange        + More
PF00010   HLH

Interpro

IPR011598   bHLH_dom        + More
IPR036638   HLH_DNA-bd_sf       
IPR003650   Orange_dom       

SUPFAM

SSF47459   SSF47459       

Gene 3D

4.10.280.10    

CDD

cd00083  HLH

ProteinModelPortal

H9J798   A0A2H1WJX5   A0A2A4ISU6   A0A212EH70   A0A194Q2Q6   A0A194RCC4   + More
A0A0L7LBB9   D6X189   Q8T306   B5A7J9   A0A0F7II78   A0A0T6BBZ1   J9JVV3   A0A2H8TV71   A0A1W4XEE8   A0A336LPM3   A0A2S2R3K5   N6TQ44   A0A1J1J523   A0A1B6CL34   A0A023EQ79   A0A0C9REB0   A0A182GQD4   Q16NK4   U5EY94   A0A088A8V4   B0WDP0   A0A0L0CL81   A0A2A3EJJ6   A0A232EQZ9   A0A1Q3FI64   A0A0L7R3R9   A0A1Q3FI77   A0A067QJU3   A0A154PQ90   A0A182V0F6   B6EBG4   A0A1L8DG73   A0A1B6LLL5   A0A182X4S5   U4UEP8   A0A182N7Q8   A0A195F830   A0A182TSF6   A0A1B0C854   A0A182YNI9   A0A182I4S4   A0A182QTJ3   Q7Q509   E2C1B6   A0A182KNC7   T1DJS5   A0A195DKM5   A0A182WIC7   A0A195D7I2   K7J0Y2   A0A182PHT1   A0A182R2G0   A0A0J7L399   A0A195B2S5   A0A158NNH0   E2AUT4   A0A0M8ZTI6   A0A2H4N701   F4WQH7   A0A151WWM7   A0A2P6KEB2   A0A026VZJ9   B4PFK6   A0A1I8MJM2   B4HK14   Q95UA9   P14003   A0A1Z5KY33   A0A1W4USH5   A0A2R5LKL5  

PDB

2MH3     E-value=1.44327e-17,     Score=217

KEGG

101742467    K09090 hairy and enhancer of split, invertebrate | (RefSeq) protein hairy

GO

GO:0006355   GO:0046983   GO:0003677   GO:0005634   GO:0050767   GO:0030154   GO:0001227   GO:0000977   GO:0000122   GO:0009952   GO:0070888   GO:0008134   GO:0000902   GO:0001666   GO:0035239   GO:0007424   GO:0007435   GO:0007399   GO:0007431   GO:0035289   GO:0045892   GO:0035290   GO:0061024   GO:0031323   GO:0007366   GO:0000978   GO:0016491   GO:0016638   GO:0016021   GO:0004674   GO:0009058   GO:0016742   GO:0003824  

Subcellular location

Nucleus  

Length:

261

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.39256

Exp number, first 60 AAs:

0.00084

Total prob of N-in:

0.02389

outside

1  -  261

 

 

Pi

292.102508

Theta

181.928639

Tajima's D

1.885929

CLR

0.032224

CSRT

0.859157042147893

Interpretation

Uncertain