Gene

KWMTBOMO04415

Annotation

PREDICTED:_malate_dehydrogenase?_mitochondrial-like_[Bombyx_mori]

Location

Bomo_Chr8(+):6371604-6372668      View in EpiBrowser

Full name

Malate dehydrogenase      

Location in the cell

Extracellular   Reliability : 2.198

CDS

ATGGAAAATTATAGTACTGGCCCGGCCGGTATGAAAGTCACTATTTGTGGAGCAGCCGGCGCTACAGGTCAACCTTTAGCGCTGCTACTAAAACAATGTCCGTTATTAGATGAAATAGCGCTTTACGATATAACTGCAACGTGCGGCTACGGTATGGAATTAAGTCACGTAGACACAAAGTGTAAGGTGTCATCGTTTTCTGGACGACATATGCTGTGCGACGCTTTAAAGGTTTTTAATTCCTACCTATGTTGA

Protein

MENYSTGPAGMKVTICGAAGATGQPLALLLKQCPLLDEIALYDITATCGYGMELSHVDTKCKVSSFSGRHMLCDALKVFNSYLC

Catalytic Activity

(S)-malate + NAD(+) = H(+) + NADH + oxaloacetate

Similarity

Belongs to the LDH/MDH superfamily.
Belongs to the heat shock protein 70 family.

Uniprot

A0A194PWC6   A0A212EI10   A0A194RH50   A0A2H1W1J4   E0VBN9   N6TM90   + More
J3JWU1   A0A2P8XRP9   A0A1Y1NL29   A0A1Y3AQX6   B3NZ92   B4QUH7   A0A1W4U941   B4PL86   B4IB85   Q9VEB1   B4NG95   A0A1B6DR34   A0A1B6CAU2   B3MTR2   A0A3M7QEX4   A0A1B6CEJ0   D6X178   E0VRQ6   A0A1A9X227   B4K7H4   A0A0M4EPV2   A0A383VW84   V5GPU7   A0A0V1P134   A0A2J7Q6U6   A0A0V1IF51   A0A0L0BXC1   A0A0V1BNH0   A0A0V0ZVE0   A0A0V0TUX3   A0A0V1BNJ5   A0A0V1DAN4   A0A0V1EX99   A0A0V1KCA1   A0A0V0YL88   A0A0V0YLK2   A0A0V0YL10   A0A0V1G0H6   A0A0V1KC83   A0A0V1G029   A0A0V1KC67   A0A0V0YKI9   A0A0V1EXG2   A0A0V1G0E3   A0A0V1EXL8   A0A0V1KC70   A0A0V1IEL0   A0A0V1EXT1   A0A0V0VHF4   A0A226DK24   A0A0V0TUZ8   A0A0V0ZVX5   A0A0V0SKB4   A0A0V1BML4   A0A0V0SKA3   A0A0V0ZUY2   A0A0V0W3Y7   A0A0V0VHE0   A0A0V0TV03   A0A0V0VHD9   A0A0V1BNV3   A0A0V1DAC4   A0A0V0ZVB3   A0A1Y3F315   A0A0V0TV16   A0A0V1DB44   A0A0V0VHE2   A0A0V1LTZ1   A0A0V0SJZ7   A0A0V0W475   A0A0V1P0S1   A0A0V1LU59   A0A0V1DAU6   A0A0V0ZW94   A0A0V0TW63   A0A0V0W449   A0A0V1BMZ1   C3UTD0   A0A132AM33   A0A0V0VIF2   A0A1A9X226   A0A1L8EI00   A0A0V1ME18   A0A0V1MER6   A0A0V1ME95   A0A0V1ME08   I1BQQ7  

EC Number

1.1.1.37

Pubmed

26354079    22118469    20566863    23537049    22516182    29403074    + More
28004739    17994087    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    30375419    18362917    19820115    26108605    19364528    26555130    19578406   

EMBL

KQ459589    KPI97681.1    AGBW02014758    OWR41100.1    KQ460397    KPJ15261.1    + More
ODYU01005767    SOQ46960.1    DS235033    EEB10795.1    APGK01029451    KB740735    ENN79133.1    BT127709    AEE62671.1    PYGN01001465    PSN34678.1    GEZM01002090    JAV97375.1    MUJZ01063727    OTF70849.1    CH954181    EDV48634.1    CM000364    EDX12477.1    CM000160    EDW95868.1    CH480827    EDW44643.1    AE014297    AY119152    BT029274    AAF55516.1    AAM51012.1    ABK30911.1    CH964251    EDW83312.1    GEDC01009168    JAS28130.1    GEDC01026681    JAS10617.1    CH902623    EDV30193.1    REGN01006372    RNA09752.1    GEDC01025457    JAS11841.1    KQ971372    EFA10587.1    DS235494    EEB16062.1    CH933806    EDW15318.1    CP012526    ALC47877.1    FNXT01000908    SZX69170.1    GALX01004849    JAB63617.1    JYDM01000063    KRZ89858.1    NEVH01017450    PNF24298.1    JYDS01000213    KRZ21234.1    JRES01001197    KNC24655.1    JYDH01000025    KRY38486.1    JYDQ01000078    KRY16429.1    JYDJ01000134    KRX42826.1    KRY38487.1    JYDI01000020    KRY58599.1    JYDR01000004    KRY78477.1    JYDV01000004    KRZ44858.1    JYDU01000006    KRY00849.1    KRY00851.1    KRY00848.1    JYDT01000012    KRY91634.1    KRY78483.1    KRZ44863.1    KRY91632.1    KRY78479.1    KRZ44859.1    KRY00850.1    KRZ21232.1    KRY78478.1    KRZ44862.1    KRY91633.1    KRY78480.1    KRY78476.1    KRZ44864.1    KRZ21233.1    KRY78481.1    KRZ44860.1    JYDN01000035    KRX62955.1    LNIX01000017    OXA45539.1    KRX42825.1    KRY16428.1    JYDL01000004    KRX27084.1    KRY38485.1    KRX27083.1    KRY16427.1    JYDK01000282    KRX70484.1    KRX62958.1    KRX42827.1    KRX62959.1    KRY38488.1    KRY58601.1    KRY16431.1    LVZM01000034    OUC50069.1    KRX42824.1    KRY58600.1    KRX62956.1    JYDW01000004    KRZ63002.1    KRX27085.1    KRX70487.1    KRZ89860.1    KRZ63003.1    KRY58602.1    KRY16430.1    KRX42823.1    KRX70488.1    KRY38489.1    FJ654718    ACP18839.1    JXLN01018606    KPM12024.1    KRX62957.1    GFDG01000570    JAV18229.1    JYDO01000126    KRZ69869.1    KRZ69870.1    KRZ69871.1    KRZ69868.1    CH476733    EIE78537.1   

Proteomes

UP000053268    UP000007151    UP000053240    UP000009046    UP000019118    UP000245037    + More
UP000008711    UP000000304    UP000192221    UP000002282    UP000001292    UP000000803    UP000007798    UP000007801    UP000276133    UP000007266    UP000091820    UP000009192    UP000092553    UP000256970    UP000054924    UP000235965    UP000054805    UP000037069    UP000054776    UP000054783    UP000055048    UP000054653    UP000054632    UP000054826    UP000054815    UP000054995    UP000054681    UP000198287    UP000054630    UP000054673    UP000243006    UP000054721    UP000054843    UP000009138   

PRIDE

Q9VEB1    B3MTR2   

Pfam

PF02866   Ldh_1_C        + More
PF00056   Ldh_1_N
PF00572   Ribosomal_L13
PF00012   HSP70

Interpro

IPR001236   Lactate/malate_DH_N        + More
IPR036291   NAD(P)-bd_dom_sf       
IPR022383   Lactate/malate_DH_C       
IPR015955   Lactate_DH/Glyco_Ohase_4_C       
IPR001557   L-lactate/malate_DH       
IPR010097   Malate_DH_type1       
IPR001252   Malate_DH_AS       
IPR036899   Ribosomal_L13_sf       
IPR005822   Ribosomal_L13       
IPR013126   Hsp_70_fam       
IPR029047   HSP70_peptide-bd_sf       
IPR029048   HSP70_C_sf       
IPR018181   Heat_shock_70_CS       

SUPFAM

SSF56327   SSF56327        + More
SSF51735   SSF51735       
SSF52161   SSF52161       
SSF100934   SSF100934       
SSF100920   SSF100920       

Gene 3D

3.90.110.10     3.90.1180.10     1.20.1270.10     2.60.34.10    

CDD

cd00392  Ribosomal_L13

ProteinModelPortal

A0A194PWC6   A0A212EI10   A0A194RH50   A0A2H1W1J4   E0VBN9   N6TM90   + More
J3JWU1   A0A2P8XRP9   A0A1Y1NL29   A0A1Y3AQX6   B3NZ92   B4QUH7   A0A1W4U941   B4PL86   B4IB85   Q9VEB1   B4NG95   A0A1B6DR34   A0A1B6CAU2   B3MTR2   A0A3M7QEX4   A0A1B6CEJ0   D6X178   E0VRQ6   A0A1A9X227   B4K7H4   A0A0M4EPV2   A0A383VW84   V5GPU7   A0A0V1P134   A0A2J7Q6U6   A0A0V1IF51   A0A0L0BXC1   A0A0V1BNH0   A0A0V0ZVE0   A0A0V0TUX3   A0A0V1BNJ5   A0A0V1DAN4   A0A0V1EX99   A0A0V1KCA1   A0A0V0YL88   A0A0V0YLK2   A0A0V0YL10   A0A0V1G0H6   A0A0V1KC83   A0A0V1G029   A0A0V1KC67   A0A0V0YKI9   A0A0V1EXG2   A0A0V1G0E3   A0A0V1EXL8   A0A0V1KC70   A0A0V1IEL0   A0A0V1EXT1   A0A0V0VHF4   A0A226DK24   A0A0V0TUZ8   A0A0V0ZVX5   A0A0V0SKB4   A0A0V1BML4   A0A0V0SKA3   A0A0V0ZUY2   A0A0V0W3Y7   A0A0V0VHE0   A0A0V0TV03   A0A0V0VHD9   A0A0V1BNV3   A0A0V1DAC4   A0A0V0ZVB3   A0A1Y3F315   A0A0V0TV16   A0A0V1DB44   A0A0V0VHE2   A0A0V1LTZ1   A0A0V0SJZ7   A0A0V0W475   A0A0V1P0S1   A0A0V1LU59   A0A0V1DAU6   A0A0V0ZW94   A0A0V0TW63   A0A0V0W449   A0A0V1BMZ1   C3UTD0   A0A132AM33   A0A0V0VIF2   A0A1A9X226   A0A1L8EI00   A0A0V1ME18   A0A0V1MER6   A0A0V1ME95   A0A0V1ME08   I1BQQ7  

PDB

4WLV     E-value=0.000422923,     Score=96

KEGG

101741175    K00026 malate dehydrogenase [EC:1.1.1.37] | (RefSeq) malate dehydrogenase, mitochondrial-like

GO

GO:0016616   GO:0005975   GO:0006099   GO:0030060   GO:0019752   GO:0006108   GO:0005739   GO:0006919   GO:0035209   GO:0035096   GO:0035071   GO:0043068   GO:0016615   GO:0043067   GO:0005759   GO:0055114   GO:0035070   GO:0005737   GO:0016491   GO:0016021   GO:0006412   GO:0003735   GO:0005840   GO:0005524   GO:0050909   GO:0016020   GO:0004930   GO:0007186   GO:0004674   GO:0009058   GO:0016742   GO:0003824  

PANTHER

PTHR19375  

Length:

84

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.73811

Exp number, first 60 AAs:

0.73758

Total prob of N-in:

0.22196

outside

1  -  84

 

 

Pi

228.58513

Theta

152.092365

Tajima's D

1.561439

CLR

0

CSRT

0.804909754512274

Interpretation

Uncertain