Gene

KWMTBOMO04414

Annotation

gustatory_receptor_68_[Bombyx_mori]

Location

Bomo_Chr8(-):6368517-6369943      View in EpiBrowser

Full name

Gustatory receptor       + More
Gustatory receptor 68a      

Location in the cell

PlasmaMembrane   Reliability : 3.766

CDS

ATGCCGTTATCGTTGAAACAACTGGAATTGATTTACATAAAGGCTTTTGAACTGAAAAGAGATATCAATAAAGCTTTTGAAGCTCCAATATTGTTGACTACAATGCAATGTTTTCACTCAATAGTAAGCGAATCACATATCATCTACCATGGTGCGGTAATGGAGCCACACATGGTACTACATTCAATAATGAATTGCTCTGTTTGGATACTATATCAGCTATTCAAATTATATATATTAGCTTCAACAGGTCATTTGCTACAGGAGAAGATACAACATTTTTCAAATCTAATACACTTCCATGGAAAAGGATTAACCGTGTATGGATTATTCCCATTGGATGGCACCTTAATGTTCAAAGTCGTTGCTTCAGCTGCGATGTACCTTATTATTTTAGTTCAGTTTGATAAAAGAAATTAA

Protein

MPLSLKQLELIYIKAFELKRDINKAFEAPILLTTMQCFHSIVSESHIIYHGAVMEPHMVLHSIMNCSVWILYQLFKLYILASTGHLLQEKIQHFSNLIHFHGKGLTVYGLFPLDGTLMFKVVASAAMYLIILVQFDKRN

Description

Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Dsx-dependent essential component of pheromone-driven courtship behavior (PubMed:12971900). Recognizes a female pheromone involved in the second step (tapping step) of the courtship display which is essential for efficient execution of the entire courtship sequence and timely mating (PubMed:12971900). Required for detection of the male sex pheromone CH503 which is transferred from males to females during mating and inhibits courtship behavior by other males (PubMed:26083710). Gr68a-expressing neurons in the male foreleg relay signals to the suboesophageal zone (SEZ) and courtship suppression is mediated by the release of the neuropeptide tachykinin from a cluster of 8-10 neurons in the SEZ (PubMed:26083710).

Similarity

Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family.
Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr21a subfamily.

Keywords

Behavior   Cell membrane   Complete proteome   Glycoprotein   Membrane   Receptor   Reference proteome   Transducer   Transmembrane   Transmembrane helix  

Feature

chain  Gustatory receptor 68a

Uniprot

F8WPI3   A0A3S2PEY1   A0A0V0J185   A0A223HD94   A0A345BF03   A0A2H1W1K2   + More
A0A0V0J2M4   A0A345BF07   A0A0V0J1G5   A0A1X9P7N0   A0A223HDH3   A0A223HDA0   A0A223HCX5   A0A0K8TVN5   A0A223HDI3   A0A0V0J1A1   A0A223HCW4   A0A223HDG2   A0A223HDA5   A0A223HDI0   A0A223HDA9   A0A0K8TUH2   A0A223HCW5   K7IUE9   A0A182UZ77   A0A1J1J099   B0WFG0   A0A3L9LWA8   A0A232FAC2   A0A1S4KKK6   A0A1S4JG72   A0A067RKK0   A0A1J1IXS9   J9HZ11   J9HSV8   J9EA72   A0A1S4FHY1   J9HSW2   Q170E5   A0A1S4FI97   J9HIL0   A0A1S4FHZ2   J9HFV3   J9HIL4   A0A1S4FI52   J9HZ06   A0A2P9JYB9   A0A1S4FHZ7   A0A182GFK6   A0A182QNT4   A0A182FRY3   A0A084W085   A5JHN2   A0A182YNA0   K7J4H3   A0A182XNX6   A0A154PGK2   B3NH01   A0A182HK22   A0A182VW97   A0A182NR18   A0A182WQQ3   A0A2R7WZH0   A5JHN3   A0A182R551   A2AXB7   A0A182FZN8   A0A067QUQ3   C9QPG7   Q9VTN0  

Pubmed

21709218    27006164    28150741    29727827    26017144    20075255    + More
28648823    24845553    17510324    26483478    24438588    17541681    25244985    17994087    10731132    12537572    11516643    12971900    22031876    26083710   

EMBL

AB600837    BAK52800.1    RSAL01000063    RVE49494.1    GDKB01000015    JAP38481.1    + More
KY283690    AST36349.1    MG820656    AXF48827.1    ODYU01005767    SOQ46961.1    GDKB01000016    JAP38480.1    MG820660    AXF48831.1    GDKB01000018    JAP38478.1    KX084517    ARO76472.1    KY283770    AST36429.1    KY283693    AST36352.1    KY283561    AST36221.1    GCVX01000100    JAI18130.1    KY283772    AST36431.1    GDKB01000017    JAP38479.1    KY283554    KY283560    AST36214.1    AST36220.1    KY283771    AST36430.1    KY283692    AST36351.1    KY283769    AST36428.1    KY283694    AST36353.1    GCVX01000103    JAI18127.1    KY283559    AST36219.1    AAZX01005844    CVRI01000065    CRL05760.1    DS231917    EDS26197.1    KB465648    RLZ02140.1    NNAY01000540    OXU27796.1    KK852415    KDR24352.1    CVRI01000063    CRL04888.1    CH477475    EJY57725.1    EJY57718.1    EJY57721.1    EJY57723.1    EAT40327.2    EJY57719.1    EJY57722.1    EJY57724.1    EJY57720.1    KY817111    AVH87327.1    JXUM01059729    JXUM01059730    KQ562069    KXJ76746.1    AXCN02001482    ATLV01019096    KE525262    KFB43629.1    EF502095    ABQ57301.1    KQ434899    KZC10989.1    CH954178    EDV51458.1    APCN01000814    KK856124    PTY24943.1    EF502096    ABQ57302.1    AM292376    CAL23188.2    KK852927    KDR13678.1    BT100081    ACX61622.3    AE014296   

Proteomes

UP000283053    UP000002358    UP000075903    UP000183832    UP000002320    UP000215335    + More
UP000027135    UP000008820    UP000069940    UP000249989    UP000075886    UP000069272    UP000030765    UP000076408    UP000076407    UP000076502    UP000008711    UP000075840    UP000075920    UP000075884    UP000075900    UP000000803   

PRIDE

F8WPI3    Q9VTN0   

Pfam

PF08395   7tm_7

Interpro

IPR013604   7TM_chemorcpt       

ProteinModelPortal

F8WPI3   A0A3S2PEY1   A0A0V0J185   A0A223HD94   A0A345BF03   A0A2H1W1K2   + More
A0A0V0J2M4   A0A345BF07   A0A0V0J1G5   A0A1X9P7N0   A0A223HDH3   A0A223HDA0   A0A223HCX5   A0A0K8TVN5   A0A223HDI3   A0A0V0J1A1   A0A223HCW4   A0A223HDG2   A0A223HDA5   A0A223HDI0   A0A223HDA9   A0A0K8TUH2   A0A223HCW5   K7IUE9   A0A182UZ77   A0A1J1J099   B0WFG0   A0A3L9LWA8   A0A232FAC2   A0A1S4KKK6   A0A1S4JG72   A0A067RKK0   A0A1J1IXS9   J9HZ11   J9HSV8   J9EA72   A0A1S4FHY1   J9HSW2   Q170E5   A0A1S4FI97   J9HIL0   A0A1S4FHZ2   J9HFV3   J9HIL4   A0A1S4FI52   J9HZ06   A0A2P9JYB9   A0A1S4FHZ7   A0A182GFK6   A0A182QNT4   A0A182FRY3   A0A084W085   A5JHN2   A0A182YNA0   K7J4H3   A0A182XNX6   A0A154PGK2   B3NH01   A0A182HK22   A0A182VW97   A0A182NR18   A0A182WQQ3   A0A2R7WZH0   A5JHN3   A0A182R551   A2AXB7   A0A182FZN8   A0A067QUQ3   C9QPG7   Q9VTN0  

KEGG

100653406    K08471 gustatory receptor | (RefSeq) Gr68; gustatory receptor 68

GO

GO:0050909   GO:0016021   GO:0007165   GO:0005886   GO:0016544   GO:0019236   GO:0050912   GO:0008527   GO:0016020   GO:0004930   GO:0007186   GO:0004674   GO:0009058   GO:0016742   GO:0003824  

PANTHER

PTHR21143  

Subcellular location

Cell membrane  

Length:

139

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

35.38215

Exp number, first 60 AAs:

1.74558

Total prob of N-in:

0.46142

outside

1  -  109

TMhelix

110  -  132

inside

133  -  139

 

 

Pi

287.318492

Theta

219.361733

Tajima's D

0.975464

CLR

0

CSRT

0.655117244137793

Interpretation

Uncertain