Silkworm Genome Informatics Database

Gene

KWMTBOMO04364

Pre Gene Modal

BGIBMGA005255

Annotation

PREDICTED:_tyrosine-protein_phosphatase_non-receptor_type_4_[Bombyx_mori]

Location

Bomo_Chr8(-):4439187-4459852 View in EpiBrowser

Location in the cell

Nuclear Reliability : 1.956

CDS

ATGATCGAGAGTGTTTCGAGAAGAGCTTTCAGCAGTTCGAGTGGTACATACAACGTTAGAGCTTCGGAGCTTGCGCGCGACAGGAAACTTTGTGTATTCAATGTTACAGTTCAGTTTTTGGACGATACCCAGCAGACATTTCAAATTGAGAAAAAAGCAAAGGGCAGTGTCCTGCTTCAACAAGTATTTGAACATCTCGAGTTAATAGAAAAGGATTATTTTGGATTGCAATACACTGAAAACGGCTATCCTCCGAATGCCAGTAACACGGAGATAACGCGCTGGTTGGACAGTAGTAAATCGGTCAAGAAACAGATAGGCGTCAATGCCCAGTTCTGGTTGGCCGTACGCTTCTATCCGCCCGAACCGTCACGTTTGGCCGAAGAATACACAAGGTACTTGCTCTGTCTGCAACTGAGGAAGTTGCTTCTCGATGGACGCATGGTAGCTCCGAAGAACACGGCGTTACTCCTGGCTTCGTTCACTGTTCAAGCCGAAATAGGTGACCACAACGATTCGGAACATTCTTCGGGCTACCTGTCCGAATTCCGTTTGTTGCCGAAACAGAACGCCGAGGACGAGCGTCGGATCCGCGAGCTCCACAAGATGCACAAGGGGCAGTCGCCCGCCGATGCGGACGCGAATTTCCTCGAGCACGCCAAACGCTTAGACTGCTATGGCGTCGATTGTCATCCAGCTAAAGACTACAACGGCAAAGACATATTTATTGGCGTAACGTCAATCGGTATAGTCGTATTCCAGAACAACGTACGCGTGAATACATTCTCTTGGAGTAAAATCGTCAAGATTTCCTTCAAGAAGAAGCAGTTCTTTATACAGCTAAAACGTGAACCCTCGGAGTCGTACGACACAGTTCTCGGTTTCAACATGCAGTCGAGTCGCGCCGCCAAAGCCCTCTGGCGCTGCAGCGTGGAGCGGCACGGCTTCTTCCGGTTGCGGGCGCCGCGGCGACGGCCGCTGTTCGAAGCCCTGGGCGCGCTGGCCGGGATCACTGCTCCGGCGGTGCCCCGGACAGAAACCCAGGCCTTGGAAGATGCGAGACGATCTAGATCATCGAACAGGAACTTTGTGAGACGCAGCAGCAGCCGTACCCGCGACCGCTCGTCGACCACCGCGTCGCCGAGCAGCGCGCCCGTCCCGTGCCGCGGTTCCAGGGTGACGTCACACACCGAGCCCGCGCCCCGCCCCGCCTGGACGCCCGGGGACGACGAGCCCCCCCAACCAGAACGGACCGAAGGAGACATCCTCAAGCACTTCGTCAGAATCCCTCTGACGTATGTGGACGAGTCGGAATCGTGTTCGGACGGCGAGGGGCGCGGCGCGGCGGGGGACGAGGGCGGCGGCGCGGGGGGCGGGGGCGAGGACGCGGTGTGCATACGGCTGGCGCCCGGCGCCGACGGACTGTTCGGGTTCAACGTGCGGGGGGGAGGGGCGGCGCCCGTGCTCGTGTCGCGAGTGGCGCCGCGGACACGGAAGCACCTACAGGAGGGTGACCAGGTGATATCGATAAACGGAACCGATGTCGAGGAGCTGACGCACGAGCAGGTCGTTCAACTCATCAGGACCACGAGGGGAGTGCTGACTCTGCTCGTCAAACCAAATGCAGTGTACGTGACGGCGGACAGCGCGGTGGAGGAGCCGGCCGTGTTCTTCGTGCCGATGGCGGGGCAGTACGAGGGGAACGCGCTCGAGCAGTCCATGCTGCTGCTGGGTGACGGGCTGGCGAGCGGCGCGGCGCTGCGACAGTACGAGACGCTGCTGCGGCGGCAGCCCGACGAGCCCACGGCCGCCTCGAAGCTCCCGCACAACATCAACAAGAACAGATACAAGGATATCGCACCTTACGATGCGACCCGAGTGATTCTGAACAACGGACCCACAGGAGATTACATCAACGCTTCCTACATCAACATGCCGATACCGAATTCTGATTTAGTACTGACCTACATCGCCACACAAGGTCCGTTGGCATCAACTGTGGGTGATTTCTGGCAAATGGTCTGGGAATCGGAGAGCAGTTTGATTGTCATGTTAACGGTTGTGTCCGAACGAGGGAGGGCCAAGTGCCACCAATATTGGCCCAAAGTTGGGACCACGCCGTTGAAGGCCACCAACGCACTGACCGTCCTGACGAACAGTGAACAGAATTTCGGACATTACATCAGGAGAGAAATGACTTTAAAGGAGAGCAGCGGCGCTTCTCGCAACGTGACGCAGCTGCAGTACACGGCGTGGCCGGACCACGGCGTGCCTGAAGACGCGGCCGCCTTCATATCCTTCACCCAGCTGTGCTCAAACCTCAGGAATCATAGAGCCGTGATGCCGTCGTCGACCGACGAGGCGGGTTCGGAGGAGCGCGTCGTGGAGCCGCCGATGGTGGTGCACTGCTCGGCGGGCGTGGGCCGCACCGGCGCGCTCGTGCTGGCCGAGACCGCGCTGGAGCTGCTGGCGCGCCGCCTGCCGCTGTACCCGCTCGACCTCGTGCGGGCCATGCGCGCGCAGCGACCCATGTGCATACAGAACTCGAATCAATACAAATTCGTCTGCGAGAGCATACAAGCTGCGTACGCACAAGGCTTCAAGAAAACATCGTCTGAAAGTGAATCGAATAGTAACTGA

Protein

MIESVSRRAFSSSSGTYNVRASELARDRKLCVFNVTVQFLDDTQQTFQIEKKAKGSVLLQQVFEHLELIEKDYFGLQYTENGYPPNASNTEITRWLDSSKSVKKQIGVNAQFWLAVRFYPPEPSRLAEEYTRYLLCLQLRKLLLDGRMVAPKNTALLLASFTVQAEIGDHNDSEHSSGYLSEFRLLPKQNAEDERRIRELHKMHKGQSPADADANFLEHAKRLDCYGVDCHPAKDYNGKDIFIGVTSIGIVVFQNNVRVNTFSWSKIVKISFKKKQFFIQLKREPSESYDTVLGFNMQSSRAAKALWRCSVERHGFFRLRAPRRRPLFEALGALAGITAPAVPRTETQALEDARRSRSSNRNFVRRSSSRTRDRSSTTASPSSAPVPCRGSRVTSHTEPAPRPAWTPGDDEPPQPERTEGDILKHFVRIPLTYVDESESCSDGEGRGAAGDEGGGAGGGGEDAVCIRLAPGADGLFGFNVRGGGAAPVLVSRVAPRTRKHLQEGDQVISINGTDVEELTHEQVVQLIRTTRGVLTLLVKPNAVYVTADSAVEEPAVFFVPMAGQYEGNALEQSMLLLGDGLASGAALRQYETLLRRQPDEPTAASKLPHNINKNRYKDIAPYDATRVILNNGPTGDYINASYINMPIPNSDLVLTYIATQGPLASTVGDFWQMVWESESSLIVMLTVVSERGRAKCHQYWPKVGTTPLKATNALTVLTNSEQNFGHYIRREMTLKESSGASRNVTQLQYTAWPDHGVPEDAAAFISFTQLCSNLRNHRAVMPSSTDEAGSEERVVEPPMVVHCSAGVGRTGALVLAETALELLARRLPLYPLDLVRAMRAQRPMCIQNSNQYKFVCESIQAAYAQGFKKTSSESESNSN

Catalytic Activity

H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate

Uniprot

H9J6W3 A0A3S2LQG3 A0A212EY08 A0A0N1ID26 A0A2H1V7A6 A0A194Q7C9 + More
A0A158NJY3 A0A0C9QHK5 A0A195BIV2 D6WV44 A0A0K8S8Y4

Pubmed

19121390 22118469 26354079 21347285 18362917 19820115 + More

EMBL

BABH01028381 BABH01028382 RSAL01000030 RVE51707.1 AGBW02011632 OWR46376.1 + More
KQ459695 KPJ20419.1 ODYU01000861 SOQ36262.1 KQ459580 KPI99310.1 ADTU01018470 ADTU01018471 ADTU01018472 GBYB01010082 GBYB01010083 GBYB01014128 JAG79849.1 JAG79850.1 JAG83895.1 KQ976465 KYM84287.1 KQ971363 EFA07782.1 GBRD01016616 JAG49210.1

Proteomes

UP000005204 UP000283053 UP000007151 UP000053240 UP000053268 UP000005205 + More
UP000078540 UP000007266

PRIDE

H9J6W3

Pfam

PF00102   Y_phosphatase        + More
PF00373   FERM_M
PF09380   FERM_C
PF00595   PDZ
PF09379   FERM_N
PF08736   FA

Interpro

IPR035963   FERM_2        + More
IPR016130   Tyr_Pase_AS
IPR019749   Band_41_domain
IPR029021   Prot-tyrosine_phosphatase-like
IPR014352   FERM/acyl-CoA-bd_prot_sf
IPR003595   Tyr_Pase_cat
IPR029071   Ubiquitin-like_domsf
IPR000299   FERM_domain
IPR018980   FERM_PH-like_C
IPR000242   PTPase_domain
IPR001478   PDZ
IPR011993   PH-like_dom_sf
IPR036034   PDZ_sf
IPR019748   FERM_central
IPR019747   FERM_CS
IPR041783   PTPN3/4_FERM_C
IPR000387   TYR_PHOSPHATASE_dom
IPR018979   FERM_N
IPR014847   FERM-adjacent

SUPFAM

SSF47031   SSF47031        + More
SSF52799   SSF52799
SSF54236   SSF54236
SSF50156   SSF50156

Gene 3D

1.20.80.10 2.30.29.30 3.90.190.10

CDD

cd13189 FERM_C_PTPN4_PTPN3_like
cd14473 FERM_B-lobe

ProteinModelPortal

H9J6W3 A0A3S2LQG3 A0A212EY08 A0A0N1ID26 A0A2H1V7A6 A0A194Q7C9 + More
A0A158NJY3 A0A0C9QHK5 A0A195BIV2 D6WV44 A0A0K8S8Y4

PDB

2I75 E-value=1.07555e-65, Score=638

KEGG

101737573 K18037 tyrosine-protein phosphatase non-receptor type 4 [EC:3.1.3.48] | (RefSeq) tyrosine-protein ph

GO

GO:0005856 GO:0004725 GO:0031032 GO:0005515 GO:0016311 GO:0016791 GO:0006470 GO:0004674 GO:0009058 GO:0016742 GO:0003824

Length:

879

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0295099999999999

Exp number, first 60 AAs:

0.00019

Total prob of N-in:

0.00119

outside

1 - 879

Pi

247.717851

Theta

171.40046

Tajima's D

1.556772

CLR

0.168872

CSRT

0.7985600719964

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics