Gene

KWMTBOMO04345  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA005262

Annotation

PREDICTED:_4-hydroxyphenylpyruvate_dioxygenase-like_[Bombyx_mori]

Location

Bomo_Chr8(-):3998071-4009369      View in EpiBrowser

Full name

4-hydroxyphenylpyruvate dioxygenase      

Location in the cell

Cytoplasmic   Reliability : 3.542

CDS

ATGACGACTTACACGGACAAGGGCAGAAAGCCGGACGATGGTCGTTTCTTGGCTTTTGACCACGTCACGTTTTGGGTTTCGAACGCCAAACAAGCGGCCAGTTACTACGTGACGAGGTTTGGCTTCGAGCCATTGGCTTACAGCGGTCTGGAGACGGGTTCTAGACAGATTTCGTCTCATGCCGTCAGAATGAATAAGATAATCTTCGTGTTTCAAGCGCAATATGAGCCTGTGGAAACAGAATTCGTAAACGAAGTGGCAATTCATGGTGACTTCGTGAAAGACGTAGCCTTCCAAGTGGAAAACTTGGACTACATATTGGAGTATGCAAGGAAACAGGGAGCGAAGGTCGTCAAGGATCTGTGGGAAGAAAAAGATCAATACGGCGTTGTCAGAATGGCTACGTTGAAAACGTACGGCAGTAATACTCACACTCTAGTCGATCGTTCTAAATATACCGGACCATTTTTGCCGGGATACCAACTATTAGAGAAAGATCCGATCAGCAAATATTTACCCAAAGTGGAAATAAACTTTATAGATCACATTGTTGGGAACCAGCCAGAGAACGAAATGGAGGAAGCCGCTTCGTGGTACGAAAGATGCCTCCAATTCCACAGATTCTGGTCAGTTGACGACAAGCAAGTTTGCACAGAATATTCCGCTCTGCGGTCAGTTGTGATGGCGAACTGGGAGGAAACGGTCAAGGTGCCGATCAACGAGCCAGCCGCCGGGAAGAGGAAGAGTCAGATACAGGAATACGTGGAGTACCACGGCGGAGCTGGAGTTCAGCACATCGCTATCAATACAGAGGACATTATTACTGCTATCGAAAATCTACGCGAGAGAGGCGTAGAATTCCTCTCGATACCTTCAAAATACTACAACCTAATACGGGAACGTTTGAAGCAAAGTAAAGTGCGCGTGGCGGAAAGTATCGATGTTTTGGAACGCCTCAACATACTCATAGATTACGACGACGACGGTTATCTACTGCAAATCTTCACGAAGAACACTCAAGACAGACCCACGCTCTTCTTAGAGGTCATACAACGGCGGAATCACAATGGCTTCGGGGCGGGTAACTTCAAAACTCTATTCGAATCAATAGAGTTGGAACAGGAAAAACGCGGCAACTTGTGA

Protein

MTTYTDKGRKPDDGRFLAFDHVTFWVSNAKQAASYYVTRFGFEPLAYSGLETGSRQISSHAVRMNKIIFVFQAQYEPVETEFVNEVAIHGDFVKDVAFQVENLDYILEYARKQGAKVVKDLWEEKDQYGVVRMATLKTYGSNTHTLVDRSKYTGPFLPGYQLLEKDPISKYLPKVEINFIDHIVGNQPENEMEEAASWYERCLQFHRFWSVDDKQVCTEYSALRSVVMANWEETVKVPINEPAAGKRKSQIQEYVEYHGGAGVQHIAINTEDIITAIENLRERGVEFLSIPSKYYNLIRERLKQSKVRVAESIDVLERLNILIDYDDDGYLLQIFTKNTQDRPTLFLEVIQRRNHNGFGAGNFKTLFESIELEQEKRGNL

Cofactor

Fe cation

Similarity

Belongs to the 4HPPD family.

Uniprot

H9J6X0   A0A2H1W9R5   A0A2A4IS65   I4DJI5   A0A212EYA1   A0A194Q189   + More
A0A194QMV1   A0A2A4ISS0   A0A232F978   D6WZP4   K7J3E2   A0A0U2N329   A0A0N0U440   A0A2A3EPS1   A0A088ACK9   A0A1Y1L7P5   A0A154PCW7   E2BIZ1   A0A0C9RMG1   A0A2P8XHR9   E2AE27   A0A1L8E2X1   E9IWI6   A0A026WR60   A0A2J7PQ32   A0A0L0BKZ9   Q16FX9   A0A1W4WLA9   A0A1A9WH59   Q16SY0   A0A1A9V553   A0A1S4G2A6   D3TQN4   A0A158NF97   B3M9A0   A0A1I8QEL0   A0A182Q9D3   A0A3B0JAW4   A0A336MHT6   Q29DD3   A0A1B6IK83   A0A2Y9D3F6   A0A182LI36   Q7Q2T3   A0A2M4AGP9   A0A182JAR9   A0A1Q3FM07   B4LGD0   A0A067QPW8   B4IUG7   B3NIM3   A0A0J9UQ37   Q9VPF3   A0A182UNA3   W8B5L7   B4IYZ9   B4IAB1   B0WBB9   A0A1B6G1S6   B4QRZ7   W5JMN3   A0A1W4W7N0   A0A182UEF0   A0A1B6M4D0   T1E8I4   A0A0M5JBQ3   B4N6M5   B4KY40   A0A2C9JS97   A0A034W5X0   A0A0A9Y321   A0A023FAR3   A0A146LY37   A0A182MNP5   A0A195C642   A0A1I8MWB3   A0A087T5J7   A0A0P4W1F5   A0A1B2G378   N6TCJ3   J3JY23   A0A195FM03   V4A0B7   A0A210PRQ4   C3ZV79   A0A3Q1GX52   A0A0P5F559   A0A0P5XAL6   A0A3Q7X063   A0A0P5QA72   I3MUI5   A0A3P9BSL5   A0A3P8PMU8   G7PJ72   F7GF23   A0A2K6BN68   A0A0P5NZL2   A0A287AI19   A0A1A8U441   A0A3B4GR92  

Pubmed

19121390    22651552    22118469    26354079    28648823    18362917    + More
19820115    20075255    28004739    20798317    29403074    21282665    24508170    26108605    17510324    20353571    21347285    17994087    15632085    20966253    12364791    14747013    17210077    24845553    17550304    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    24495485    20920257    23761445    15562597    25348373    25401762    25474469    26823975    25315136    27129103    27476595    23537049    22516182    23254933    28812685    18563158    25186727    22002653    17431167    30723633   

EMBL

BABH01028340    BABH01028341    ODYU01007234    SOQ49835.1    NWSH01008285    PCG62625.1    + More
AK401453    BAM18075.1    AGBW02011602    OWR46441.1    KQ459580    KPI99321.1    KQ461196    KPJ06290.1    NWSH01007858    PCG62781.1    NNAY01000645    OXU27215.1    KQ971372    EFA10456.1    KR181950    ALJ76674.1    KQ435840    KOX71401.1    KZ288204    PBC33226.1    GEZM01062589    JAV69604.1    KQ434874    KZC09692.1    GL448543    EFN84336.1    GBYB01014597    JAG84364.1    PYGN01002085    PSN31547.1    GL438827    EFN68260.1    GFDF01001239    JAV12845.1    GL766526    EFZ15088.1    KK107119    EZA58527.1    NEVH01022640    PNF18444.1    JRES01001711    KNC20613.1    CH478368    EAT33142.1    CH477663    EAT37578.1    CCAG010007514    EZ423736    ADD20012.1    ADTU01013709    CH902618    EDV40084.2    AXCN02001910    OUUW01000002    SPP77142.1    UFQT01001230    SSX29585.1    CH379070    EAL30481.3    GECU01020376    JAS87330.1    AAAB01008968    EAA13250.3    GGFK01006635    MBW39956.1    GFDL01006497    JAV28548.1    CH940647    EDW70459.1    KK853076    KDR11729.1    CH891904    EDX00031.1    CH954178    EDV52519.1    CM002912    KMZ00796.1    AE014296    BT012317    AAF51601.1    AAS77442.1    GAMC01014147    JAB92408.1    CH916366    EDV97707.1    CH480826    EDW44224.1    DS231878    EDS42263.1    GECZ01013371    JAS56398.1    CM000363    EDX11243.1    ADMH02001127    ETN64019.1    GEBQ01009219    JAT30758.1    GAMD01002738    JAA98852.1    CP012525    ALC45106.1    CH964161    EDW80014.2    CH933809    EDW18742.2    GAKP01009275    JAC49677.1    GBHO01016147    JAG27457.1    GBBI01000145    JAC18567.1    GDHC01007073    JAQ11556.1    AXCM01006965    KQ978287    KYM95641.1    KK113525    KFM60386.1    GDKW01001094    JAI55501.1    KX572142    ANZ03346.1    APGK01035502    APGK01035503    KB740926    ENN78019.1    BT128147    AEE63108.1    KQ981490    KYN41356.1    KB201305    ESO97258.1    NEDP02005541    OWF39134.1    GG666687    EEN43551.1    GDIQ01267568    JAJ84156.1    GDIP01076462    GDIQ01068717    LRGB01001361    JAM27253.1    JAN26020.1    KZS12608.1    GDIQ01123049    JAL28677.1    AGTP01058528    CM001286    EHH66799.1    JSUE03008047    JSUE03008048    CM001263    EHH21273.1    GDIQ01142393    JAL09333.1    AEMK02000096    DQIR01168319    HDB23796.1    HADY01006665    HAEJ01002617    SBS43074.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053268    UP000053240    UP000215335    + More
UP000007266    UP000002358    UP000053105    UP000242457    UP000005203    UP000076502    UP000008237    UP000245037    UP000000311    UP000053097    UP000235965    UP000037069    UP000008820    UP000192223    UP000091820    UP000078200    UP000092444    UP000005205    UP000007801    UP000095300    UP000075886    UP000268350    UP000001819    UP000076407    UP000075882    UP000007062    UP000075880    UP000008792    UP000027135    UP000002282    UP000008711    UP000000803    UP000075903    UP000001070    UP000001292    UP000002320    UP000000304    UP000000673    UP000192221    UP000075902    UP000092553    UP000007798    UP000009192    UP000076420    UP000075883    UP000078542    UP000095301    UP000054359    UP000019118    UP000078541    UP000030746    UP000242188    UP000001554    UP000257200    UP000076858    UP000286642    UP000005215    UP000265160    UP000265100    UP000009130    UP000006718    UP000233120    UP000008227    UP000261460   

PRIDE

H9J6X0    A0A088ACK9    Q9VPF3   

Pfam

PF00903   Glyoxalase

Interpro

IPR004360   Glyas_Fos-R_dOase_dom        + More
IPR041735   4OHPhenylPyrv_dOase_C       
IPR029068   Glyas_Bleomycin-R_OHBP_Dase       
IPR037523   VOC       
IPR005956   4OHPhenylPyrv_dOase       
IPR041736   4OHPhenylPyrv_dOase_N       
IPR018146   Glyoxalase_1_CS       

SUPFAM

SSF54593   SSF54593       

Gene 3D

3.10.180.10    

CDD

cd07250  HPPD_C_like
cd08342  HPPD_N_like

ProteinModelPortal

H9J6X0   A0A2H1W9R5   A0A2A4IS65   I4DJI5   A0A212EYA1   A0A194Q189   + More
A0A194QMV1   A0A2A4ISS0   A0A232F978   D6WZP4   K7J3E2   A0A0U2N329   A0A0N0U440   A0A2A3EPS1   A0A088ACK9   A0A1Y1L7P5   A0A154PCW7   E2BIZ1   A0A0C9RMG1   A0A2P8XHR9   E2AE27   A0A1L8E2X1   E9IWI6   A0A026WR60   A0A2J7PQ32   A0A0L0BKZ9   Q16FX9   A0A1W4WLA9   A0A1A9WH59   Q16SY0   A0A1A9V553   A0A1S4G2A6   D3TQN4   A0A158NF97   B3M9A0   A0A1I8QEL0   A0A182Q9D3   A0A3B0JAW4   A0A336MHT6   Q29DD3   A0A1B6IK83   A0A2Y9D3F6   A0A182LI36   Q7Q2T3   A0A2M4AGP9   A0A182JAR9   A0A1Q3FM07   B4LGD0   A0A067QPW8   B4IUG7   B3NIM3   A0A0J9UQ37   Q9VPF3   A0A182UNA3   W8B5L7   B4IYZ9   B4IAB1   B0WBB9   A0A1B6G1S6   B4QRZ7   W5JMN3   A0A1W4W7N0   A0A182UEF0   A0A1B6M4D0   T1E8I4   A0A0M5JBQ3   B4N6M5   B4KY40   A0A2C9JS97   A0A034W5X0   A0A0A9Y321   A0A023FAR3   A0A146LY37   A0A182MNP5   A0A195C642   A0A1I8MWB3   A0A087T5J7   A0A0P4W1F5   A0A1B2G378   N6TCJ3   J3JY23   A0A195FM03   V4A0B7   A0A210PRQ4   C3ZV79   A0A3Q1GX52   A0A0P5F559   A0A0P5XAL6   A0A3Q7X063   A0A0P5QA72   I3MUI5   A0A3P9BSL5   A0A3P8PMU8   G7PJ72   F7GF23   A0A2K6BN68   A0A0P5NZL2   A0A287AI19   A0A1A8U441   A0A3B4GR92  

PDB

5EC3     E-value=5.86806e-134,     Score=1223

KEGG

101746796    K00457 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27] | (RefSeq) 4-hydroxyphenylpyruvate dioxyg

PATHWAY

00130    Ubiquinone and other terpenoid-quinone biosynthesis - Bombyx mori (domestic silkworm)
00350    Tyrosine metabolism - Bombyx mori (domestic silkworm)
00360    Phenylalanine metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0003868   GO:0046872   GO:0009072   GO:0000139   GO:0005789   GO:0006572   GO:0004462   GO:0051213   GO:0016701   GO:0008270   GO:0004672   GO:0005515   GO:0004674   GO:0009058   GO:0016742   GO:0003824   GO:0055114  

PANTHER

PTHR11959  

Length:

380

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0406000000000001

Exp number, first 60 AAs:

0.03857

Total prob of N-in:

0.10694

outside

1  -  380

 

 

Pi

33.799381

Theta

170.676436

Tajima's D

-1.652083

CLR

0.976969

CSRT

0.0430478476076196

Interpretation

Uncertain