Gene

KWMTBOMO04323

Pre Gene Modal

BGIBMGA014106

Annotation

PREDICTED:_SUZ_domain-containing_protein_1_[Amyelois_transitella]

Location

Bomo_Chr8(-):3238496-3240745      View in EpiBrowser

Full name

DNA topoisomerase 2      

Location in the cell

Nuclear   Reliability : 3.651

CDS

ATGTACATAAAACAAGGAAGAATGAAGAATCTATGGTTGTCAGTCAACATGGCGGCCCAGGATGAAGTTGACGTATGTGAAAGTTGGGAAGATATGGATGAAATTATTGGTCTGGAACAGAATATCAGGTTAAACAGTGAGAGTCCCACAGAAAACCCGCCAGCTATTTCTCTAAGGGATTGCAAGGTTACTGTTGAAGAGAACGCGTGTATCGGATCGCAGTGCATGATGCCGGAGCCTGCTATTCGCATACTAAAAAGGCCATCATCTTCTGGCAGTGGGCAGTTAAACGGAGAGAATCGTGCCCGACCGGTCAAAACTCTAGAGCAGAGGCAAAAGGAGTATGAACAGGCTCGTCTCAGGATCCTAGGCGAGGCTCGGAGTCCTGAAGATATTATTGATGATAAACTCACCAGGCTACAAGACAAATTACAAGCAAATAATCTTAATGACAGTCAATCAAATAATAAGAAAAATGGTGAAAACGCTAAAAGTAAAGAACGTAAAGTGTTATCTCGGCTTCCACCTGGAGCTACCCCAGCTGGAGTATTTCCATCTCCACCTCCACGAGGAGTGCTTGTTATCCGTACCCCTCGTGGCCCTGATGGCACCAAAGAATATGAGTATACAAGTACAATACTAAAGTTAGTGGTGTTCCAGACTGCAGTCACCTACAGTGATGGTCCGTGCTTAGCTGCAGAGTTTTAG

Protein

MYIKQGRMKNLWLSVNMAAQDEVDVCESWEDMDEIIGLEQNIRLNSESPTENPPAISLRDCKVTVEENACIGSQCMMPEPAIRILKRPSSSGSGQLNGENRARPVKTLEQRQKEYEQARLRILGEARSPEDIIDDKLTRLQDKLQANNLNDSQSNNKKNGENAKSKERKVLSRLPPGATPAGVFPSPPPRGVLVIRTPRGPDGTKEYEYTSTILKLVVFQTAVTYSDGPCLAAEF

Description

Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.

Catalytic Activity

ATP-dependent breakage, passage and rejoining of double-stranded DNA.

Subunit

Homodimer.

Similarity

Belongs to the type II topoisomerase family.

Uniprot

H9JX41   A0A2H1VBC8   A0A212FCL8   A0A194Q042   A0A3S2LUJ4   A0A0L7LSR5   + More
A0A194RGT8   E0VUS4   A0A2R7WKH0   A0A1W4WPI5   A0A195FM17   A0A026WAA4   A0A1B6LC63   A0A158NF31   A0A151WHV4   A0A1B6H831   A0A3L8DFS9   A0A195E936   A0A195C449   T1I0J3   R4G482   A0A1B6CJC6   E2AE13   A0A087T041   E2C9Y6   A0A1B0D8G1   A0A226E541   A0A0N8CDS3   A0A0N8C719   C4WUF4   A0A0P6CJX5   A0A0P5D4S7   A0A0P4XAX6   A0A2S2P4D7   A0A2I4BDK2   A0A3M7STJ7   A0A087YJB5   A0A3B3UK18  

EC Number

5.6.2.3

Pubmed

19121390    22118469    26354079    26227816    20566863    24508170    + More
21347285    30249741    20798317    30375419   

EMBL

BABH01032045    ODYU01001403    SOQ37534.1    AGBW02009166    OWR51482.1    KQ459583    + More
KPI98663.1    RSAL01000190    RVE44697.1    JTDY01000162    KOB78505.1    KQ460211    KPJ16540.1    DS235793    EEB17130.1    KK854989    PTY20136.1    KQ981490    KYN41371.1    KK107295    EZA52980.1    GEBQ01018727    JAT21250.1    ADTU01013722    KQ983106    KYQ47398.1    GECU01036831    JAS70875.1    QOIP01000009    RLU18759.1    KQ979479    KYN21344.1    KQ978287    KYM95629.1    ACPB03022822    GAHY01001585    JAA75925.1    GEDC01023778    JAS13520.1    GL438827    EFN68246.1    KK112761    KFM58480.1    GL453916    EFN75223.1    AJVK01027392    LNIX01000007    OXA51626.1    GDIP01141663    LRGB01000642    JAL62051.1    KZS17301.1    GDIQ01108507    GDIP01050725    JAL43219.1    JAM52990.1    ABLF02030628    AK341041    BAH71524.1    GDIQ01090213    JAN04524.1    GDIP01161208    JAJ62194.1    GDIP01245263    JAI78138.1    GGMR01011625    MBY24244.1    REGN01000788    RNA39113.1    AYCK01022333   

Proteomes

UP000005204    UP000007151    UP000053268    UP000283053    UP000037510    UP000053240    + More
UP000009046    UP000192223    UP000078541    UP000053097    UP000005205    UP000075809    UP000279307    UP000078492    UP000078542    UP000015103    UP000000311    UP000054359    UP000008237    UP000092462    UP000198287    UP000076858    UP000007819    UP000192220    UP000276133    UP000028760    UP000261500   

PRIDE

H9JX41   

Pfam

PF12901   SUZ-C        + More
PF12752   SUZ
PF00204   DNA_gyraseB
PF00521   DNA_topoisoIV
PF16898   TOPRIM_C
PF02518   HATPase_c
PF01751   Toprim

Interpro

IPR024771   SUZ        + More
IPR039228   SZRD1       
IPR024642   SUZ-C       
IPR014721   Ribosomal_S5_D2-typ_fold_subgr       
IPR006171   TOPRIM_domain       
IPR013506   Topo_IIA_bsu_dom2       
IPR002205   Topo_IIA_A/C       
IPR013759   Topo_IIA_B_C       
IPR013758   Topo_IIA_A/C_ab       
IPR018522   TopoIIA_CS       
IPR034157   TOPRIM_TopoII       
IPR036890   HATPase_C_sf       
IPR013760   Topo_IIA-like_dom_sf       
IPR003594   HATPase_C       
IPR020568   Ribosomal_S5_D2-typ_fold       
IPR013757   Topo_IIA_A_a_sf       
IPR001241   Topo_IIA       
IPR031660   TOPRIM_C       

SUPFAM

SSF55874   SSF55874        + More
SSF54211   SSF54211       
SSF56719   SSF56719       

Gene 3D

1.10.268.10     3.30.230.10     3.30.565.10     3.40.50.670     3.90.199.10    

CDD

cd00075  HATPase_c
cd03365  TOPRIM_TopoIIA

ProteinModelPortal

H9JX41   A0A2H1VBC8   A0A212FCL8   A0A194Q042   A0A3S2LUJ4   A0A0L7LSR5   + More
A0A194RGT8   E0VUS4   A0A2R7WKH0   A0A1W4WPI5   A0A195FM17   A0A026WAA4   A0A1B6LC63   A0A158NF31   A0A151WHV4   A0A1B6H831   A0A3L8DFS9   A0A195E936   A0A195C449   T1I0J3   R4G482   A0A1B6CJC6   E2AE13   A0A087T041   E2C9Y6   A0A1B0D8G1   A0A226E541   A0A0N8CDS3   A0A0N8C719   C4WUF4   A0A0P6CJX5   A0A0P5D4S7   A0A0P4XAX6   A0A2S2P4D7   A0A2I4BDK2   A0A3M7STJ7   A0A087YJB5   A0A3B3UK18  

KEGG

101736521    no KO assigned | (RefSeq) SUZ domain-containing protein 1

GO

GO:0003677   GO:0003916   GO:0005524  

PANTHER

PTHR31796  

Length:

235

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0187

Exp number, first 60 AAs:

0

Total prob of N-in:

0.28266

outside

1  -  235

 

 

Pi

311.187238

Theta

224.156807

Tajima's D

1.222622

CLR

0.491087

CSRT

0.719814009299535

Interpretation

Uncertain