Gene

KWMTBOMO04289  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA014574

Annotation

PREDICTED:_lipase_1-like_[Bombyx_mori]

Location

Bomo_Chr8(+):1962170-1963650      View in EpiBrowser

Full name

Lipase      

Location in the cell

PlasmaMembrane   Reliability : 1.417

CDS

ATGGTATATACGAGTGCAATTTTCCACCTGGTCATGATGATACTCCTGTATCTGAGTAGTACTGGTTATTCACTCACTCCAATTGTGGAAGATCTCTTTTTGGAAAAGCTTGGAGGTGACGTGTTAAGGGAGTTTCCAAAACTAGATGAGAACGTGATCAAAATTAATGTACCAGCAGACGCTAAGCTGAACTTCAACGCTCTCGCCGCGAAATACGGGCACCCGTGCGAGGAACATTATGTCGAGTCAGAGGACGGTTATGTAACCAAGTTATTTCATTTACCGGGAGACAGGAAACGGCCGGTGCTCATGATGCACGGCCTCTTCGAATCTGCTGATACTTTTATCATCAGAGGCAACAGATCAATGGCGATATCCCTCGCGAACGCTGGCTACGACGTGTGGCTGGGAAACATGAGAGGAAACAAACATTCCCGGAGACACGTTACTCTGAATCCCGACAAAGATGCCGAATTTTGGAACTTCAGTTACCACGAAATGGCGTTGTACGATCTACCTGCGACTATCGACTACATCCTGGGTCACACCGGCCAGACACAGATCTATGGTATCGCCCATTCTCAGGGCAACAATATTTTCTTCGCAATGACAGCAATGTTGCCACAATATAACACAAAGATCAGGGTTTTGATTTCGTTAGGACCGGCAGTCCATATTGAGAATATTAAATCGCCGACGAAAATACTAGTTCAGCTGTCTCCTCTTATAAACTATCTGTTCGAAGGGATCGGCAATGAGGAAATTTTGCCGGAGGGGGAAATTCTTAGGAGCCAACTGCAAAAAGTCTGCCCCTTAGGATTGCCGGGATATGTTTTATGCGTTCAGTTGATTATATTTCAACTAGCCGGTTACAATACGGCAGAACTGGAGCAAGAATTCTTCCCGGTTGTACTCGGTCATAGCCCCAGTGGAACTTCAAGGAAAAACTTCAATCATTTAGTACAGTCGGGGAAATACAAGCGTTTTGCTTATTACGATGCCGGCGCTGAAGAAAATATCCGACTATATGGAAGAGAGGAACCTCCTTTGTACGATCTCAGCGTGGTCACCATGAAGGTGGCTATTTTTGCTGGAAACAACGACAAATTGGTCGTTCTCAAGGATACCGAGAGACTGCGAGACGAGCTGACAAATGTTGTCGAGTACAGGGTATTGGAACCGAGAAAATGGAATCACTTGGATTTCGTATGGGGGAGGAATGCCAACAAGTTTTTGTTTCCATATATTTTTGAATTGCTGCACAAATATTAG

Protein

MVYTSAIFHLVMMILLYLSSTGYSLTPIVEDLFLEKLGGDVLREFPKLDENVIKINVPADAKLNFNALAAKYGHPCEEHYVESEDGYVTKLFHLPGDRKRPVLMMHGLFESADTFIIRGNRSMAISLANAGYDVWLGNMRGNKHSRRHVTLNPDKDAEFWNFSYHEMALYDLPATIDYILGHTGQTQIYGIAHSQGNNIFFAMTAMLPQYNTKIRVLISLGPAVHIENIKSPTKILVQLSPLINYLFEGIGNEEILPEGEILRSQLQKVCPLGLPGYVLCVQLIIFQLAGYNTAELEQEFFPVVLGHSPSGTSRKNFNHLVQSGKYKRFAYYDAGAEENIRLYGREEPPLYDLSVVTMKVAIFAGNNDKLVVLKDTERLRDELTNVVEYRVLEPRKWNHLDFVWGRNANKFLFPYIFELLHKY

Similarity

Belongs to the AB hydrolase superfamily. Lipase family.

Feature

chain  Lipase

Uniprot

H9JYF4   H9JT83   H9JYF5   H9JSY7   A0A194Q1A5   A0A0L7L277   + More
A0A0N1IGF0   A0A2H1VHX0   A0A0L7KQV5   A0A1E1WS39   A0A2W1BHX8   H9JXK1   H9JSY6   A0A212F2S9   A0A194QRY3   H9JXH3   A0A0L7L5K9   I4DP30   A0A212F0W8   H9JSY5   A0A194Q1X8   A0A212FGM8   H9JSX2   A0A212F2S4   S4PBS0   A0A0P4WII3   A0A2A4JBG8   V5I953   A0A1D2MRG2   A0A2J7QW32   A0A151X254   A0A0M4ENQ4   A0A226E1Q5   E2B370   A0A182H3N2   B4KKR5   B4KKR4   A0A067QLF8   A0A1Y9H2R7   A0A2H1WUD0   W5JF51   B4KKR3   A0A195E3Z0   B0W6G8   A0A1D2MVM7   A0A195FK23   A0A182QF27   A0A067R0F9   A0A0J9R159   A0A0K8UT86   B4JE82   A0A2J7QRG7   A0A1Y9J0S8   B4KKS1   A0A0L7KXY5   A0A151IQS0   B4HWR7   A0A195AVW7   A0A2A4JCC5   A0A182FR70   A0A182KX99   Q7QH37   A0A1I8JTB8   A0A2A4J9X8   A0A2H1VT20   A0A158P269   Q9VKT9   A0A182SY57   A0A194R2Y3   A0A0J9TKN6   Q9VKT2   Q8T3X7   B4LUK3   M9PCU5   A0A194QDF4   B0W6G4   A0A0N1PFF0   B3N5D9   A0A2J7PUL3   A0A0T6BEX7   B3MJK2   X1WSL9   B4MWP6   A0A067QXT1   A0A182UTW8   A0A182LC36   M9MRM3   A0A182TUN5   B4P0R7   A0A1A9UTK2   A0A1W4UT02   Q16MC6   B3N5D0   Q16F27   A0A226EG24   B4HWS6   F5HKY3   A0A1B6C389   B4MWP4   A0A0Q5WBH0  

Pubmed

19121390    26354079    26227816    28756777    22118469    22651552    + More
23622113    27289101    20798317    26483478    17994087    24845553    20920257    23761445    18057021    22936249    20966253    12364791    14747013    17210077    21347285    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304    17510324   

EMBL

BABH01043411    BABH01034815    BABH01038893    BABH01038894    KQ459580    KPI99336.1    + More
JTDY01008561    JTDY01003454    KOB64514.1    KOB69530.1    KQ460480    KPJ14361.1    ODYU01002476    SOQ40012.1    JTDY01007194    KOB65389.1    GDQN01001224    JAT89830.1    KZ150080    PZC73881.1    BABH01032765    BABH01038896    AGBW02010690    OWR48036.1    KQ461196    KPJ06301.1    BABH01032763    JTDY01002846    KOB70611.1    AK403268    BAM19670.1    AGBW02011015    OWR47367.1    KPI99333.1    AGBW02008642    OWR52889.1    BABH01038949    OWR48034.1    GAIX01002709    JAA89851.1    GDRN01044880    JAI66895.1    NWSH01002215    PCG68894.1    GALX01003535    JAB64931.1    LJIJ01000666    ODM95481.1    NEVH01009768    PNF32784.1    KQ982580    KYQ54458.1    CP012523    ALC38095.1    LNIX01000009    OXA50396.1    GL445305    EFN89852.1    JXUM01107700    KQ565165    KXJ71265.1    CH933807    EDW12729.2    EDW12728.1    KK853197    KDR09957.1    ODYU01011128    SOQ56675.1    ADMH02001587    ETN61958.1    EDW12727.1    KRG03395.1    KQ979657    KYN19900.1    DS231848    EDS36642.1    LJIJ01000475    ODM97066.1    KQ981523    KYN40354.1    AXCN02000090    KK852827    KDR15388.1    CM002910    KMY89574.1    GDHF01022533    JAI29781.1    CH916368    EDW03602.1    NEVH01011896    PNF31184.1    EDW12735.1    JTDY01004649    KOB67911.1    KQ976755    KYN08590.1    CH480818    EDW52462.1    KQ976731    KYM76202.1    NWSH01002126    PCG69082.1    AAAB01008820    EAA05393.4    APCN01002227    PCG68895.1    ODYU01004246    SOQ43916.1    ADTU01007002    AE014134    AY089586    AAF52971.1    AAL90324.1    KQ460855    KPJ11879.1    KMY89575.1    AAF52978.1    AGB92892.1    AY089450    AAL90188.1    CH940649    EDW64189.1    AGB92891.1    KQ459193    KPJ03000.1    EDS36638.1    KQ461072    KPJ09861.1    CH954177    EDV59018.1    NEVH01021196    PNF20013.1    LJIG01001091    KRT85849.1    CH902620    EDV32370.2    ABLF02039332    CH963857    EDW76535.2    KK853131    KDR10945.1    ADV37035.1    CM000157    EDW87962.1    CH477866    EAT35491.1    EDV59009.1    CH478517    EAT32843.1    LNIX01000004    OXA56097.1    EDW52471.1    AAAB01008879    EGK96944.1    GEDC01029317    GEDC01024313    GEDC01024096    GEDC01020251    JAS07981.1    JAS12985.1    JAS13202.1    JAS17047.1    EDW76533.1    KQS70596.1   

Proteomes

UP000005204    UP000053268    UP000037510    UP000053240    UP000007151    UP000218220    + More
UP000094527    UP000235965    UP000075809    UP000092553    UP000198287    UP000008237    UP000069940    UP000249989    UP000009192    UP000027135    UP000075884    UP000000673    UP000078492    UP000002320    UP000078541    UP000075886    UP000001070    UP000076407    UP000078542    UP000001292    UP000078540    UP000069272    UP000075882    UP000007062    UP000075840    UP000005205    UP000000803    UP000075901    UP000008792    UP000008711    UP000007801    UP000007819    UP000007798    UP000075903    UP000075902    UP000002282    UP000078200    UP000192221    UP000008820   

PRIDE

H9JYF4    H9JT83    H9JYF5    H9JSY7    H9JXK1    H9JSY6    + More
H9JXH3    H9JSY5    H9JSX2    Q9VKT9    Q9VKT2    Q8T3X7    M9PCU5    M9MRM3   

Pfam

PF00561   Abhydrolase_1        + More
PF04083   Abhydro_lipase
PF12146   Hydrolase_4

Interpro

IPR025483   Lipase_euk        + More
IPR000073   AB_hydrolase_1       
IPR029058   AB_hydrolase       
IPR006693   AB_hydrolase_lipase       
IPR022742   Hydrolase_4       

SUPFAM

SSF53474   SSF53474       

Gene 3D

3.40.50.1820    

ProteinModelPortal

H9JYF4   H9JT83   H9JYF5   H9JSY7   A0A194Q1A5   A0A0L7L277   + More
A0A0N1IGF0   A0A2H1VHX0   A0A0L7KQV5   A0A1E1WS39   A0A2W1BHX8   H9JXK1   H9JSY6   A0A212F2S9   A0A194QRY3   H9JXH3   A0A0L7L5K9   I4DP30   A0A212F0W8   H9JSY5   A0A194Q1X8   A0A212FGM8   H9JSX2   A0A212F2S4   S4PBS0   A0A0P4WII3   A0A2A4JBG8   V5I953   A0A1D2MRG2   A0A2J7QW32   A0A151X254   A0A0M4ENQ4   A0A226E1Q5   E2B370   A0A182H3N2   B4KKR5   B4KKR4   A0A067QLF8   A0A1Y9H2R7   A0A2H1WUD0   W5JF51   B4KKR3   A0A195E3Z0   B0W6G8   A0A1D2MVM7   A0A195FK23   A0A182QF27   A0A067R0F9   A0A0J9R159   A0A0K8UT86   B4JE82   A0A2J7QRG7   A0A1Y9J0S8   B4KKS1   A0A0L7KXY5   A0A151IQS0   B4HWR7   A0A195AVW7   A0A2A4JCC5   A0A182FR70   A0A182KX99   Q7QH37   A0A1I8JTB8   A0A2A4J9X8   A0A2H1VT20   A0A158P269   Q9VKT9   A0A182SY57   A0A194R2Y3   A0A0J9TKN6   Q9VKT2   Q8T3X7   B4LUK3   M9PCU5   A0A194QDF4   B0W6G4   A0A0N1PFF0   B3N5D9   A0A2J7PUL3   A0A0T6BEX7   B3MJK2   X1WSL9   B4MWP6   A0A067QXT1   A0A182UTW8   A0A182LC36   M9MRM3   A0A182TUN5   B4P0R7   A0A1A9UTK2   A0A1W4UT02   Q16MC6   B3N5D0   Q16F27   A0A226EG24   B4HWS6   F5HKY3   A0A1B6C389   B4MWP4   A0A0Q5WBH0  

PDB

1K8Q     E-value=1.62745e-53,     Score=530

KEGG

101743711    K01052 lysosomal acid lipase/cholesteryl ester hydrolase [EC:3.1.1.13] | (RefSeq) lipase 1-like

GO

GO:0016042   GO:0016788   GO:0016021   GO:0006629   GO:0016298   GO:0044255   GO:0006506   GO:0005524   GO:0016459   GO:0042555   GO:0006260   GO:0004672   GO:0048384  

SignalP

Position:   1 - 24,         Likelihood:  0.903686

 

 

Length:

423

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

22.72943

Exp number, first 60 AAs:

22.39304

Total prob of N-in:

0.98770

POSSIBLE N-term signal

sequence

inside

1  -  6

TMhelix

7  -  29

outside

30  -  423

 

 

Pi

246.569812

Theta

162.936175

Tajima's D

1.845436

CLR

0.189791

CSRT

0.857607119644018

Interpretation

Uncertain