Gene

KWMTBOMO04177

Pre Gene Modal

BGIBMGA008665

Annotation

Chymotrypsinogen_B_[Operophtera_brumata]

Location

Bomo_Chr7(-):12914038-12915211      View in EpiBrowser

Full name

Protein masquerade      

Location in the cell

Extracellular   Reliability : 2.087

CDS

ATGCTTTTTCCAGCGGGTCCGATCCCTCTGAGGGTACGCGAGGCTGAAATCCCGATAGTAAGTGACGCCGAGTGCATCCGTAAAGTGAACGCAGTCACCGAGAAGATTTTCATCCTCCCCGCGAGTTCCTTCTGCGCGGGGGGGGAGGAAGGAAACGACGCCTGTCAGGGTGATGGTGGAGGACCACTAGTGTGTCAAGACGACGGGTTCTACGAGCTGGCGGGGCTGGTGTCCTGGGGCTTCGGCTGCGGCCGCAGGGACGTACCAGGGGTCTACGTTAAGGTCTCCGCCTTCATAGGGTGGATCAATCAGATAATATCCGTCAACAATAACAATAACAACATAGACTGA

Protein

MLFPAGPIPLRVREAEIPIVSDAECIRKVNAVTEKIFILPASSFCAGGEEGNDACQGDGGGPLVCQDDGFYELAGLVSWGFGCGRRDVPGVYVKVSAFIGWINQIISVNNNNNNID

Description

In embryogenesis, has a role in somatic muscle attachment and in the development of axonal pathways probably by stabilizing cell-matrix adhesion and/or by acting as a competitive antagonist of serine proteases.

Similarity

Belongs to the peptidase S1 family.
Belongs to the peptidase S1 family. CLIP subfamily.

Keywords

Alternative splicing   Cell projection   Complete proteome   Developmental protein   Disulfide bond   Glycoprotein   Reference proteome   Repeat   Secreted   Serine protease homolog   Signal  

Feature

chain  Protein masquerade
splice variant  In isoform C.

Uniprot

A0A1B6FVP8   A0A232FI05   K7J2Z9   A0A0M9ABM3   H9JGL8   A0A0L7LBM5   + More
A0A0J7K5T0   A0A0L0CDQ7   A0A154PPQ2   A0A224XZ37   A0A034V031   A0A0L7RHX1   A0A0K8V7H3   A0A158NB79   A0A0A1XE51   A0A1A9YIH3   N6T8S3   A0A1I8Q9G9   W8BLB7   A0A1B0AKS2   U4UJF9   A0A067R6E8   A0A1A9WLK0   F4X698   A0A1A9UG58   A0A151IDY9   A0A1A9ZKD4   A0A1B0FDP0   B4HU10   A0A0A9VWZ3   A0A151X314   A0A1I8MPY4   A0A212F547   A0A182G1N0   B0WB60   Q17J66   T1GEJ5   A0A084W000   A0A182IWB1   W5JCQ1   A0A182KA83   A0A182FQS9   X1XHE5   A0A195FTP4   A0A182RNX5   A0A182XHQ6   A0A182W001   A0A182UMY6   A0A182LGH9   A0A182HTN2   A0A182LRX7   Q7QCV2   A0A182Y447   A0A182SKQ3   A0A1S3DSP4   A0A0M3QWE9   A0A151JCB9   A0A182TUV2   A0A2H8TX95   E9J5F6   E2BTC3   A0A336MLD1   A0A182Q6P9   I4DMM2   A0A182P272   E0VIF7   A0A336M1M4   A0A1W4W872   E1ZUU6   A0A182N776   A0A3B0JXJ3   A0A2J7R1K2   A0A3B0JPM7   B4LB91   Q9VZH2-2   Q9VZH2   B3NG45   B4QQG6   B4PHQ5   B4J1F0   B4L9D3   A0A1J1HYT9   A0A2W1BQR2   A0A0J9RP82   A0A3L8DLM6   Q29D77   B4N3K3   A0A026WTF4   B4H7V6   A0A146L7U5   A0A1V1G575   B3M4V9   A0A1S3DWF4   A0A2H8TJX9   A0A194Q2L6   T1HZE5   A0A2A4K3W1   A0A2S2R3Z0   A0A1W4X873   A0A2P8Z9E4  

Pubmed

28648823    20075255    19121390    26227816    26108605    25348373    + More
21347285    25830018    23537049    24495485    24845553    21719571    17994087    25401762    25315136    22118469    26483478    17510324    24438588    20920257    23761445    20966253    12364791    14747013    17210077    25244985    21282665    20798317    22651552    20566863    7851790    10731132    12537572    12537569    8817456    17550304    28756777    22936249    30249741    15632085    24508170    26823975    28410430    26354079    29403074   

EMBL

GECZ01015483    JAS54286.1    NNAY01000174    OXU30312.1    KQ435710    KOX79829.1    + More
BABH01034397    JTDY01001818    KOB72795.1    LBMM01013296    KMQ85717.1    JRES01000645    KNC29624.1    KQ435007    KZC13414.1    GFTR01003115    JAW13311.1    GAKP01022346    JAC36606.1    KQ414588    KOC70455.1    GDHF01017432    JAI34882.1    ADTU01010489    ADTU01010490    GBXI01005554    JAD08738.1    APGK01047061    APGK01047062    KB741077    ENN74098.1    GAMC01006983    GAMC01006982    JAB99572.1    JXJN01027882    KB632384    ERL94229.1    KK852669    KDR18860.1    GL888797    EGI58028.1    KQ977901    KYM98880.1    CCAG010020298    CH480817    EDW50431.1    GBHO01043450    JAG00154.1    KQ982577    KYQ54640.1    AGBW02010265    OWR48843.1    JXUM01137384    KQ568570    KXJ68952.1    DS231877    EDS42125.1    CH477234    EAT46741.2    CAQQ02391959    ATLV01019061    KE525259    KFB43544.1    ADMH02001605    ETN61856.1    ABLF02016015    KQ981272    KYN43833.1    APCN01000570    AXCM01001634    AAAB01008859    EAA08096.5    CP012525    ALC44029.1    KQ979060    KYN23168.1    GFXV01006337    MBW18142.1    GL768153    EFZ11946.1    GL450389    EFN81044.1    UFQT01001460    SSX30655.1    AXCN02000328    AK402540    BAM19162.1    DS235199    EEB13163.1    UFQT01000280    SSX22733.1    GL434297    EFN75038.1    OUUW01000002    SPP77441.1    NEVH01008206    PNF34708.1    SPP77440.1    CH940647    EDW68655.2    U18130    AE014296    AY052044    BT001597    AAC46512.1    AAF47850.1    AAK93468.1    AAN71352.1    CH954178    EDV50874.1    CM000363    EDX09172.1    CM000159    EDW93364.2    CH916366    EDV95841.1    CH933816    EDW17308.2    CVRI01000029    CRK92492.1    KZ149929    PZC77439.1    CM002912    KMY97517.1    QOIP01000006    RLU21281.1    CH379070    EAL30537.3    CH964095    EDW79208.2    KK107128    EZA58384.1    CH479219    EDW34746.1    GDHC01015333    JAQ03296.1    FX985333    BAX07346.1    CH902618    EDV40533.2    GFXV01001783    MBW13588.1    KQ459589    KPI97650.1    ACPB03014181    NWSH01000158    PCG78951.1    GGMS01015558    MBY84761.1    PYGN01000139    PSN53112.1   

Proteomes

UP000215335    UP000002358    UP000053105    UP000005204    UP000037510    UP000036403    + More
UP000037069    UP000076502    UP000053825    UP000005205    UP000092443    UP000019118    UP000095300    UP000092460    UP000030742    UP000027135    UP000091820    UP000007755    UP000078200    UP000078542    UP000092445    UP000092444    UP000001292    UP000075809    UP000095301    UP000007151    UP000069940    UP000249989    UP000002320    UP000008820    UP000015102    UP000030765    UP000075880    UP000000673    UP000075881    UP000069272    UP000007819    UP000078541    UP000075900    UP000076407    UP000075920    UP000075903    UP000075882    UP000075840    UP000075883    UP000007062    UP000076408    UP000075901    UP000079169    UP000092553    UP000078492    UP000075902    UP000008237    UP000075886    UP000075885    UP000009046    UP000192221    UP000000311    UP000075884    UP000268350    UP000235965    UP000008792    UP000000803    UP000008711    UP000000304    UP000002282    UP000001070    UP000009192    UP000183832    UP000279307    UP000001819    UP000007798    UP000053097    UP000008744    UP000007801    UP000053268    UP000015103    UP000218220    UP000192223    UP000245037   

PRIDE

H9JGL8    Q9VZH2   

Pfam

PF00089   Trypsin        + More
PF18398   CLIP_SPH_mas

Interpro

IPR009003   Peptidase_S1_PA        + More
IPR001314   Peptidase_S1A       
IPR001254   Trypsin_dom       
IPR018114   TRYPSIN_HIS       
IPR040479   CLIP_SPH_mas       

SUPFAM

SSF50494   SSF50494       

CDD

cd00190  Tryp_SPc

ProteinModelPortal

A0A1B6FVP8   A0A232FI05   K7J2Z9   A0A0M9ABM3   H9JGL8   A0A0L7LBM5   + More
A0A0J7K5T0   A0A0L0CDQ7   A0A154PPQ2   A0A224XZ37   A0A034V031   A0A0L7RHX1   A0A0K8V7H3   A0A158NB79   A0A0A1XE51   A0A1A9YIH3   N6T8S3   A0A1I8Q9G9   W8BLB7   A0A1B0AKS2   U4UJF9   A0A067R6E8   A0A1A9WLK0   F4X698   A0A1A9UG58   A0A151IDY9   A0A1A9ZKD4   A0A1B0FDP0   B4HU10   A0A0A9VWZ3   A0A151X314   A0A1I8MPY4   A0A212F547   A0A182G1N0   B0WB60   Q17J66   T1GEJ5   A0A084W000   A0A182IWB1   W5JCQ1   A0A182KA83   A0A182FQS9   X1XHE5   A0A195FTP4   A0A182RNX5   A0A182XHQ6   A0A182W001   A0A182UMY6   A0A182LGH9   A0A182HTN2   A0A182LRX7   Q7QCV2   A0A182Y447   A0A182SKQ3   A0A1S3DSP4   A0A0M3QWE9   A0A151JCB9   A0A182TUV2   A0A2H8TX95   E9J5F6   E2BTC3   A0A336MLD1   A0A182Q6P9   I4DMM2   A0A182P272   E0VIF7   A0A336M1M4   A0A1W4W872   E1ZUU6   A0A182N776   A0A3B0JXJ3   A0A2J7R1K2   A0A3B0JPM7   B4LB91   Q9VZH2-2   Q9VZH2   B3NG45   B4QQG6   B4PHQ5   B4J1F0   B4L9D3   A0A1J1HYT9   A0A2W1BQR2   A0A0J9RP82   A0A3L8DLM6   Q29D77   B4N3K3   A0A026WTF4   B4H7V6   A0A146L7U5   A0A1V1G575   B3M4V9   A0A1S3DWF4   A0A2H8TJX9   A0A194Q2L6   T1HZE5   A0A2A4K3W1   A0A2S2R3Z0   A0A1W4X873   A0A2P8Z9E4  

PDB

5GVT     E-value=6.91052e-19,     Score=224

KEGG

101736440    no KO assigned | (RefSeq) serine proteinase stubble

GO

GO:0004252   GO:0007422   GO:0061564   GO:0010976   GO:0016203   GO:0043025   GO:0005737   GO:0106030   GO:0005615   GO:0005886   GO:0007417   GO:0030424   GO:0006508   GO:0007018   GO:0008017   GO:0016021   GO:0042555   GO:0006260   GO:0004672   GO:0048384  

Subcellular location

Secreted   Localizes to vesicle-like structures in epidermal cells.   With evidence from 11 publications.
Cell projection   Localizes to vesicle-like structures in epidermal cells.   With evidence from 11 publications.
Axon   Localizes to vesicle-like structures in epidermal cells.   With evidence from 11 publications.

Length:

116

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.22705

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00939

outside

1  -  116

 

 

Pi

142.564487

Theta

126.604935

Tajima's D

-0.501236

CLR

0

CSRT

0.246687665616719

Interpretation

Uncertain