Gene

KWMTBOMO04170  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA008725

Annotation

PREDICTED:_UTP--glucose-1-phosphate_uridylyltransferase_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr7(+):12746403-12768877      View in EpiBrowser

Full name

UTP--glucose-1-phosphate uridylyltransferase      

Location in the cell

Cytoplasmic   Reliability : 2.174 Nuclear   Reliability : 1.732

CDS

ATGAAGCCAGAAACCAACGACTCCGATAAAAAGATTCGCAGTCACCAGCGGACGCCGTCAGGGTCTCGTGACTTCAAGGAGGCCACCAAACGTGATGCCCTCGCTCGACTGGAGGTGGAGCTGGAGAAGCTCATCTCCACGGCCCCGGAAACCAGGCGTCCGCAGCTCGAGAAAGAGTTCAAAGGCTTCAAGACGCTCTTCAGCAGATTCTTGGCTGAACAGGGTCCGTCGGTAACATGGGAGAAAATCGAGAAGCTTCCAGAAGGAGCTGTAATCGATTATAACAGTCTGTCCACGCCAACGACGGACAACGTGCACCATATGCTCGACAAGTTGGTGGTGGTGAAGCTTAACGGAGGCCTGGGTACATCCATGGGCTGTAAGGGCCCCAAATCGGTGATCCAAGTCCGGAATGACCTGACCTTCCTTGATCTTACCGTACAGCAAATAGAGCACTTGAACAAGACGTATAAATGCAACGTCCCACTAGTCCTGATGAACTCCTTCAACACGGATGAAGACACCCAGAAGGTGATCAGGAAGTATAAGGGTCTGAAGCTGGACATCCACACCTTCAATCAGTCCTGCCACCCTCGTATTAACAGGGAGTCACTATTGCCCATCGCTCAGAACGGTGATGTTCAAGACGATATTGAATCCTGGTATCCACCGGGTCACGGAGACTTCTACGAGTCATTCCACAATTCCGGTCTCCTACAGAAGTTCATCAACGAGGGTCGTACCTATTGCTTCATCAGCAACATCGACAACTTAGGAGCCACCGTTGACCTCAACATCTTAAGCCTGCTCCTCAACCCGGATCCTCTGCGGCCGGTTCCGGAGTTCGTCATGGAAGTGACCGACAAAACCCGTGCCGACGTCAAGGGAGGAACCCTCATACAATACGAAGACAAATTGCGGCTTTTAGAAATCGCCCAAGTGCCCAAAGAACGCGTTGACGATTTTAAATCTGTTAGCCAATTCAAGTTTTTCAACACGAACAACCTTTGGGCCAAATTGGACGCAGTTCAGCGGGTGGTCGACCAGGGGAGCCTCAACATGGAAATCATTGTCAACAACAAGCATCTATCGGACGGTATCAATGTGATTCAACTAGAGACGGCTGTGGGGGCCGCCATGAAGTGCTTCGAGGGTGGGATCGGCGTCAACGTGCCCCGCAGCAGGTTCTTGCCGGTCAAAAAGACCTCGGACTTGCTGTTGGTCATGTCCAACCTGTACAGCTTGTCCCACGGGTCCTTAGTCATGTCCTCTCAGAGGATGTTTGCCTCGACCCCCCTCGTCAAACTAGGAGACAATCATTTCGCTAAAGTCAAAGAGTACCTGAACAGGTTCGCGACCATACCGGATCTGATCGAACTGGACCATTTGACCGTTTCTGGCGACGTGACCTTCGGAAGAGGAGTGTCTTTGAAGGGCACAGTGATCATAATCGCGAATCACGGCGACCGTATCGACATCCCATCGGGTGCGATTCTCGAAAACAAAATCGTTTCTGGAAACTTAAGGATTTTGGATCACTGA

Protein

MKPETNDSDKKIRSHQRTPSGSRDFKEATKRDALARLEVELEKLISTAPETRRPQLEKEFKGFKTLFSRFLAEQGPSVTWEKIEKLPEGAVIDYNSLSTPTTDNVHHMLDKLVVVKLNGGLGTSMGCKGPKSVIQVRNDLTFLDLTVQQIEHLNKTYKCNVPLVLMNSFNTDEDTQKVIRKYKGLKLDIHTFNQSCHPRINRESLLPIAQNGDVQDDIESWYPPGHGDFYESFHNSGLLQKFINEGRTYCFISNIDNLGATVDLNILSLLLNPDPLRPVPEFVMEVTDKTRADVKGGTLIQYEDKLRLLEIAQVPKERVDDFKSVSQFKFFNTNNLWAKLDAVQRVVDQGSLNMEIIVNNKHLSDGINVIQLETAVGAAMKCFEGGIGVNVPRSRFLPVKKTSDLLLVMSNLYSLSHGSLVMSSQRMFASTPLVKLGDNHFAKVKEYLNRFATIPDLIELDHLTVSGDVTFGRGVSLKGTVIIIANHGDRIDIPSGAILENKIVSGNLRILDH

Catalytic Activity

alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-alpha-D-glucose

Similarity

Belongs to the UDPGP type 1 family.

Uniprot

H9JGS8   A0A194RHU0   A0A194PWA7   E1U7I5   A0A2W1BUV6   A0A0S1MMM3   + More
A0A1E1W5G4   A0A2A4JRX6   A0A2A4JQ81   A0A2A4JRI8   A0A2A4JS45   A0A1E1WVB3   A0A2H1W7T1   A0A1E1W9C6   A0A1E1WHG6   A0A3S2TQR1   A0A212EPR9   A0A0T6AST8   D6WPU3   A0A2J7R1R8   A0A2J7R1S7   A0A2J7R1R4   A0A1Y1LAB2   A0A067QYU1   A0A1B6CPT6   A0A1B6CUM9   A0A1B6DXY4   A0A1Y1LF18   T1DE51   A0A023EUR8   A0A1B6F8J5   A0A1B6GT97   A0A182JBG7   A0A1Q3FLA2   A0A182GHQ7   A0A1B6EKX9   A0A182RA51   A0A182QQM1   A0A1B6FUC7   A0A1Y9H383   B0WFJ8   A0A2M4BKP7   A0A1S4FB16   A0A182YQ17   Q58I82   A0A026W0X2   A0A1Y9H2U2   A0A182JS08   A0A1Q3FLG7   T1P8F9   A0A182PRS3   A0A1L8E255   A0A1Y9IVL5   W5J6Z2   T1PNE3   A0A1Y9IZZ0   A0A182LZ51   A0A182HKF0   A0A1W4WHM5   A0A2M4A3B4   A0A2M4CX13   A0A3L8DN04   A0A182TZX8   A0A2M3ZFJ9   F5HMV1   A0A1W4W669   A0A2M4A391   A0A1Y9J0B5   A0A1I8N4L5   A0A1B0CVE3   A0A034VM77   Q7PKK3   A0A1W4WGL4   D3TMX2   A0A0K8V8C7   W8B5P2   A0A1I8N4K5   A0A034VN84   A0A182UQK7   A0A0K8V683   A0A0K8WFB0   A0A023EW50   A0A1B6M968   A0A195F1K1   A0A224XEQ3   E9J656   A0A2A3E8J6   V9ICG4   A0A0Q9WSJ1   B4IXV6   A0A0Q9XET6   A0A195B242   A0A1B6MUL7   A0A0Q9XPW8   A0A1B6LL61   A0A1I8NW79   A0A158NGD1   A0A0Q9X342   E1ZYZ4   A0A1B0A749  

EC Number

2.7.7.9

Pubmed

19121390    26354079    28756777    22118469    18362917    19820115    + More
28004739    24845553    24330624    24945155    26483478    25244985    17510324    24508170    20920257    23761445    25315136    30249741    12364791    14747013    17210077    25348373    20353571    24495485    21282665    17994087    21347285    20798317   

EMBL

BABH01034380    KQ460367    KPJ15511.1    KQ459589    KPI97661.1    FJ793042    + More
ACY69181.1    KZ149929    PZC77445.1    KR821075    ALL42062.1    GDQN01008827    JAT82227.1    NWSH01000785    PCG74223.1    PCG74225.1    PCG74224.1    PCG74222.1    GDQN01000136    JAT90918.1    ODYU01006865    SOQ49093.1    GDQN01007480    JAT83574.1    GDQN01004646    JAT86408.1    RSAL01000020    RVE52571.1    AGBW02013393    OWR43492.1    LJIG01022885    KRT78224.1    KQ971354    EFA06874.2    NEVH01008202    PNF34777.1    PNF34778.1    PNF34779.1    GEZM01061319    JAV70564.1    KK852818    KDR15697.1    GEDC01021796    JAS15502.1    GEDC01020365    JAS16933.1    GEDC01006762    JAS30536.1    GEZM01061317    JAV70565.1    GALA01001187    JAA93665.1    GAPW01000876    JAC12722.1    GECZ01023222    JAS46547.1    GECZ01004117    JAS65652.1    GFDL01006698    JAV28347.1    JXUM01064342    KQ562293    KXJ76222.1    GECZ01031181    JAS38588.1    AXCN02001509    GECZ01015942    JAS53827.1    DS231918    EDS26266.1    GGFJ01004390    MBW53531.1    AY944757    CH477349    AAX47080.1    EAT42894.1    KK107533    EZA49231.1    GFDL01006658    JAV28387.1    KA644934    AFP59563.1    GFDF01001365    JAV12719.1    ADMH02002101    ETN59168.1    KA649166    KA649590    AFP64219.1    AXCM01000640    GGFK01001928    MBW35249.1    GGFL01005688    MBW69866.1    QOIP01000006    RLU21810.1    GGFM01006573    MBW27324.1    AAAB01008987    EGK97623.1    GGFK01001869    MBW35190.1    AJWK01030438    GAKP01015373    GAKP01015367    JAC43579.1    EAA43227.3    EZ422774    ADD19050.1    GDHF01017157    JAI35157.1    GAMC01021461    JAB85094.1    GAKP01015371    GAKP01015369    GAKP01015365    GAKP01015363    JAC43587.1    GDHF01018199    GDHF01003124    JAI34115.1    JAI49190.1    GDHF01002463    JAI49851.1    GAPW01001009    JAC12589.1    GEBQ01007507    JAT32470.1    KQ981864    KYN34256.1    GFTR01006942    JAW09484.1    GL768221    EFZ11766.1    KZ288349    PBC27381.1    JR039603    AEY58775.1    CH964168    KRF99230.1    CH916366    EDV96477.1    CH933809    KRG06169.1    KQ976662    KYM78546.1    GEBQ01023084    GEBQ01000395    JAT16893.1    JAT39582.1    KRG06168.1    GEBQ01015505    JAT24472.1    ADTU01014827    ADTU01014828    KRF99232.1    GL435242    EFN73684.1   

Proteomes

UP000005204    UP000053240    UP000053268    UP000218220    UP000283053    UP000007151    + More
UP000007266    UP000235965    UP000027135    UP000075880    UP000069940    UP000249989    UP000075900    UP000075886    UP000075884    UP000002320    UP000076408    UP000008820    UP000053097    UP000075881    UP000075885    UP000075920    UP000000673    UP000095301    UP000076407    UP000075883    UP000192223    UP000279307    UP000075902    UP000007062    UP000092461    UP000075903    UP000078541    UP000242457    UP000007798    UP000001070    UP000009192    UP000078540    UP000095300    UP000005205    UP000000311    UP000092445   

PRIDE

H9JGS8   

Pfam

PF01704   UDPGP        + More
PF07776   zf-AD
PF14306   PUA_2
PF01747   ATP-sulfurylase
PF15811   SVIP

Interpro

IPR016267   UDPGP_trans        + More
IPR002618   UDPGP_fam       
IPR029044   Nucleotide-diphossugar_trans       
IPR002891   APS_kinase       
IPR027417   P-loop_NTPase       
IPR025980   ATP-Sase_PUA-like_dom       
IPR002650   Sulphate_adenylyltransferase       
IPR012934   Znf_AD       
IPR031632   SVIP       
IPR024951   Sulfurylase_cat_dom       
IPR015947   PUA-like_sf       
IPR014729   Rossmann-like_a/b/a_fold       

SUPFAM

SSF53448   SSF53448        + More
SSF52540   SSF52540       
SSF88697   SSF88697       

Gene 3D

3.90.550.10     3.40.50.620    

CDD

cd00897  UGPase_euk
cd00517  ATPS
cd02027  APSK

ProteinModelPortal

H9JGS8   A0A194RHU0   A0A194PWA7   E1U7I5   A0A2W1BUV6   A0A0S1MMM3   + More
A0A1E1W5G4   A0A2A4JRX6   A0A2A4JQ81   A0A2A4JRI8   A0A2A4JS45   A0A1E1WVB3   A0A2H1W7T1   A0A1E1W9C6   A0A1E1WHG6   A0A3S2TQR1   A0A212EPR9   A0A0T6AST8   D6WPU3   A0A2J7R1R8   A0A2J7R1S7   A0A2J7R1R4   A0A1Y1LAB2   A0A067QYU1   A0A1B6CPT6   A0A1B6CUM9   A0A1B6DXY4   A0A1Y1LF18   T1DE51   A0A023EUR8   A0A1B6F8J5   A0A1B6GT97   A0A182JBG7   A0A1Q3FLA2   A0A182GHQ7   A0A1B6EKX9   A0A182RA51   A0A182QQM1   A0A1B6FUC7   A0A1Y9H383   B0WFJ8   A0A2M4BKP7   A0A1S4FB16   A0A182YQ17   Q58I82   A0A026W0X2   A0A1Y9H2U2   A0A182JS08   A0A1Q3FLG7   T1P8F9   A0A182PRS3   A0A1L8E255   A0A1Y9IVL5   W5J6Z2   T1PNE3   A0A1Y9IZZ0   A0A182LZ51   A0A182HKF0   A0A1W4WHM5   A0A2M4A3B4   A0A2M4CX13   A0A3L8DN04   A0A182TZX8   A0A2M3ZFJ9   F5HMV1   A0A1W4W669   A0A2M4A391   A0A1Y9J0B5   A0A1I8N4L5   A0A1B0CVE3   A0A034VM77   Q7PKK3   A0A1W4WGL4   D3TMX2   A0A0K8V8C7   W8B5P2   A0A1I8N4K5   A0A034VN84   A0A182UQK7   A0A0K8V683   A0A0K8WFB0   A0A023EW50   A0A1B6M968   A0A195F1K1   A0A224XEQ3   E9J656   A0A2A3E8J6   V9ICG4   A0A0Q9WSJ1   B4IXV6   A0A0Q9XET6   A0A195B242   A0A1B6MUL7   A0A0Q9XPW8   A0A1B6LL61   A0A1I8NW79   A0A158NGD1   A0A0Q9X342   E1ZYZ4   A0A1B0A749  

PDB

4R7P     E-value=0,     Score=1658

KEGG

101744836    K00963 UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] | (RefSeq) UTP--glucose-1-phosphate

PATHWAY

00040    Pentose and glucuronate interconversions - Bombyx mori (domestic silkworm)
00052    Galactose metabolism - Bombyx mori (domestic silkworm)
00500    Starch and sucrose metabolism - Bombyx mori (domestic silkworm)
00520    Amino sugar and nucleotide sugar metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0006011   GO:0003983   GO:0016021   GO:0005977   GO:0005737   GO:0008270   GO:0005524   GO:0000103   GO:0005634   GO:0004781   GO:0004020   GO:0008152   GO:0007264   GO:0042555   GO:0006260   GO:0004672   GO:0048384   GO:0070569  

Length:

513

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0358200000000001

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00599

outside

1  -  513

 

 

Pi

267.831313

Theta

171.254329

Tajima's D

1.830963

CLR

0.044444

CSRT

0.851757412129393

Interpretation

Uncertain