Gene

KWMTBOMO04163

Pre Gene Modal

BGIBMGA008672

Annotation

type_I_adipokinetic_prohormone_precursor_[Bombyx_mori]

Location

Bomo_Chr7(-):12693442-12694182      View in EpiBrowser

Full name

Adipokinetic prohormone type 2       + More
Hypertrehalosaemic prohormone      
Adipokinetic prohormone type 1      
Adipokinetic prohormone      

Location in the cell

Extracellular   Reliability : 3.856

CDS

ATGGGTCGCGCTTTGGTACTTGTGTTGATTCTGTCCGCTGCCTTGTTGGTCTGCGAAGCTCAGCTGACGTTTACTCCAGGTTGGGGCCAGGGCAAGAGATCGGAGGCCACCGACTATAGAAACGATGGATGCTCCTCTGAAGATTCCGTTTATACTATTTACAAACTGATCAAGAATGAAGCAGAGAAGTTTCTAGCGTGCCAGTCCTAA

Protein

MGRALVLVLILSAALLVCEAQLTFTPGWGQGKRSEATDYRNDGCSSEDSVYTIYKLIKNEAEKFLACQS

Description

This hormone, released from cells in the corpora cardiaca, causes release of diglycerides from the fat body and stimulation of muscles to use these diglycerides as an energy source during energy-demanding processes.

Subunit

Adipokinetic hormone precursor-related peptide (APRP) can form three type of disulfide-bond dimers: p1 (alpha-alpha), p2 (alpha-beta), and p3 (beta-beta).

Similarity

Belongs to the AKH/HRTH/RPCH family.

Keywords

Amidation   Cleavage on pair of basic residues   Direct protein sequencing   Hormone   Neuropeptide   Pyrrolidone carboxylic acid   Secreted   Signal   Flight   Disulfide bond  

Feature

peptide  Adipokinetic hormone 2
chain  Hypertrehalosaemic prohormone

Uniprot

B0LUE7   B3IUD5   A0A0S1U082   M4QFY1   A0A2H1VT60   C0HKR1   + More
A0A385H8U0   A0A1L4FNN3   Q17128   A0A0U4EI00   C0HL92   C0HL91   A0A212FKQ9   A0A2H1WI17   A0A385H8T9   A0A0C5BC69   A0A194RD19   A0A194RCE2   A0A194PWF9   F4MJ53   E2AMJ9   A8WFD9   H9JGS5   A0A0C5BEX1   A0A1Q3FTJ2   B6DE17   T1DQQ2   A0A158N7M0   C8Z3D5   B0W1A8   A0A2M3Z923   A0A2M4ANG7   A0A2M4C507   A0A0S1U0L9   P67788   N6UHE4   A0A1S3DUP8   A0A1L8DQ52   M4QEK5   A0A084VYF4   F4WLC6   A0A182FZY6   A0A2J7QLY6   A0A182J042   A0A1B0DLM1   A0A182R1D8   U5EY62   A0A182S506   A0A067RJ06   A0A345BED0   A0A182MX76   Q16NE8   A0A140F9Y3   A0A1A9YTA0   A0A1B0BHV2   A3RE77   A0A182K374   A0A182PMF7   A0A182VPI3   A0A182TPX4   A0A182LR92   A0A182XUQ9   Q27Q78   A0A182IIN3   A0A336LXR7   A0A023EB74   U3U8Q8   A0A3L8DIN6   A0A026W6Z0   A0A182NZ26   A0A140F9Y2   Q5EY02   A0A182WR25   A0A140F9Z0   A0A140F9Y5   A0A140F9Y0   A0A2M4DMR9   A0A140F9Y6   A0A1A9X5R1   A0A140F9Z1   A0A1A9URT0   A0A1B0A6U2   A0A140F9Y1   E0VV43   B8K1Y2   A0A1J1I2K1   A0A140F9Y7   P18830   P55319   A0A195BPF8   A0A140F9Y4   P18829   A0A140F9Y9   A0A140F9Y8  

Pubmed

19121390    28756777    29466015    30171635    9220026    3778476    + More
22118469    25640113    26354079    21439292    20798317    19178717    20920257    2753887    4074373    23537049    24438588    21719571    24845553    17510324    18362917    19820115    20966253    12364791    14747013    16731343    17210077    24945155    23932938    30249741    24508170    15647592    20566863    2294116    7559443    958472    8224763    2731552    2576372    2627375    1941082   

EMBL

BABH01034377    EU373445    ABY81279.1    AB298931    BAG50370.1    KT005946    + More
RSAL01000020    ALM30297.1    RVE52578.1    KC340913    KZ149929    AGH25545.1    PZC77451.1    ODYU01003991    SOQ43414.1    MH028061    AXY04230.1    KX096711    APJ36628.1    U35277    KP979739    ALX27200.1    AGBW02007996    OWR54335.1    ODYU01008799    SOQ52709.1    MH028060    AXY04229.1    KJ783477    AJM76766.1    KQ460367    KPJ15512.1    KPJ15513.1    KQ459589    KPI97662.1    FJ943774    ADB91364.1    GL440824    EFN65319.1    EU263341    AB298930    ABW97444.1    BAG50369.1    BABH01034378    KJ783476    AJM76765.1    GFDL01004125    JAV30920.1    EU934386    ACI30164.1    GAMD01002329    JAA99261.1    GGFL01015832    MBW80010.1    FN391985    CAY77163.1    DS231821    EDS44978.1    GGFM01004251    MBW25002.1    GGFK01009009    MBW42330.1    GGFJ01011276    MBW60417.1    KT005945    ALM30296.1    RVE52577.1    J04972    APGK01020368    KB740193    KB631602    ENN81145.1    ERL84541.1    MG550150    AWT50584.1    GFDF01005476    JAV08608.1    KC340912    AGH25544.1    PZC77450.1    ATLV01018364    KE525231    KFB42998.1    GL888207    EGI65089.1    NEVH01013241    PNF29558.1    AJVK01025142    AJVK01036518    AXCN02000734    GANO01002179    JAB57692.1    KT805316    KK852478    AML80834.1    KDR23008.1    MF765462    AXF48182.1    AXCM01000044    FN391987    CH477825    CAY77165.1    EAT35885.1    KT805307    AML80825.1    JXJN01014603    DQ232685    EF222289    KQ971343    ABB58740.1    ABN79649.1    EFA04704.2    DQ388479    AAAB01008984    ABD43194.1    EDO63368.1    APCN01003350    UFQS01000195    UFQT01000195    SSX01119.1    SSX21499.1    GAPW01006752    GAPW01006751    GEHC01000512    JAC06847.1    JAV47133.1    JQ082123    AB817235    AFN26934.1    BAO00932.1    QOIP01000007    RLU20186.1    KK107390    EZA51391.1    KT805306    AML80824.1    AY622321    AAV41425.1    KT805314    AML80832.1    KT805309    AML80827.1    KT805304    AML80822.1    GGFL01014651    MBW78829.1    KT805310    AML80828.1    KT805315    AML80833.1    KT805305    AML80823.1    DS235802    EEB17249.1    DQ232684    KQ971307    ABB58739.1    EFA11613.2    CVRI01000038    CRK93994.1    KT805311    AML80829.1    L08772    L08771    J05170    X86799    KQ976433    KYM87337.1    KT805308    AML80826.1    KT805313    AML80831.1    KT805312    AML80830.1   

Proteomes

UP000005204    UP000283053    UP000007151    UP000053240    UP000053268    UP000000311    + More
UP000002320    UP000019118    UP000030742    UP000079169    UP000030765    UP000007755    UP000069272    UP000235965    UP000075880    UP000092462    UP000075886    UP000075900    UP000027135    UP000075883    UP000008820    UP000092443    UP000092460    UP000007266    UP000075881    UP000075885    UP000075903    UP000075902    UP000075882    UP000076407    UP000007062    UP000075840    UP000279307    UP000053097    UP000075884    UP000075920    UP000091820    UP000078200    UP000092445    UP000009046    UP000183832    UP000078540   

PRIDE

B0LUE7    B3IUD5    A8WFD9    H9JGS5   

Pfam

PF06377   Adipokin_hormo        + More
PF04410   Gar1

Interpro

IPR010475   AKH/RPCH_hormone        + More
IPR002047   Adipokinetic_hormone_CS       
IPR009000   Transl_B-barrel_sf       
IPR040309   Naf1       
IPR038664   Gar1/Naf1_Cbf5-bd_sf       
IPR007504   H/ACA_rnp_Gar1/Naf1       

SUPFAM

SSF50447   SSF50447       

Gene 3D

2.40.10.230    

ProteinModelPortal

B0LUE7   B3IUD5   A0A0S1U082   M4QFY1   A0A2H1VT60   C0HKR1   + More
A0A385H8U0   A0A1L4FNN3   Q17128   A0A0U4EI00   C0HL92   C0HL91   A0A212FKQ9   A0A2H1WI17   A0A385H8T9   A0A0C5BC69   A0A194RD19   A0A194RCE2   A0A194PWF9   F4MJ53   E2AMJ9   A8WFD9   H9JGS5   A0A0C5BEX1   A0A1Q3FTJ2   B6DE17   T1DQQ2   A0A158N7M0   C8Z3D5   B0W1A8   A0A2M3Z923   A0A2M4ANG7   A0A2M4C507   A0A0S1U0L9   P67788   N6UHE4   A0A1S3DUP8   A0A1L8DQ52   M4QEK5   A0A084VYF4   F4WLC6   A0A182FZY6   A0A2J7QLY6   A0A182J042   A0A1B0DLM1   A0A182R1D8   U5EY62   A0A182S506   A0A067RJ06   A0A345BED0   A0A182MX76   Q16NE8   A0A140F9Y3   A0A1A9YTA0   A0A1B0BHV2   A3RE77   A0A182K374   A0A182PMF7   A0A182VPI3   A0A182TPX4   A0A182LR92   A0A182XUQ9   Q27Q78   A0A182IIN3   A0A336LXR7   A0A023EB74   U3U8Q8   A0A3L8DIN6   A0A026W6Z0   A0A182NZ26   A0A140F9Y2   Q5EY02   A0A182WR25   A0A140F9Z0   A0A140F9Y5   A0A140F9Y0   A0A2M4DMR9   A0A140F9Y6   A0A1A9X5R1   A0A140F9Z1   A0A1A9URT0   A0A1B0A6U2   A0A140F9Y1   E0VV43   B8K1Y2   A0A1J1I2K1   A0A140F9Y7   P18830   P55319   A0A195BPF8   A0A140F9Y4   P18829   A0A140F9Y9   A0A140F9Y8  

KEGG

100174839    no KO assigned | (RefSeq) AKH2; adipokinetic hormone 2

GO

GO:0005179   GO:0005576   GO:0007218   GO:0016021   GO:0007629   GO:0005732   GO:0000493   GO:0003723   GO:0042254   GO:0001522   GO:0005230   GO:0006810   GO:0042555   GO:0006260   GO:0004672   GO:0048384  

PANTHER

PTHR31633  

Subcellular location

Secreted  

SignalP

Position:   1 - 20,         Likelihood:  0.999555

 

 

Length:

69

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

17.91037

Exp number, first 60 AAs:

17.91037

Total prob of N-in:

0.80186

POSSIBLE N-term signal

sequence

inside

1  -  4

TMhelix

5  -  24

outside

25  -  69

 

 

Pi

34.198899

Theta

28.103572

Tajima's D

0.627601

CLR

1.808851

CSRT

0.557822108894555

Interpretation

Uncertain