Gene

KWMTBOMO04116

Annotation

PREDICTED:_uncharacterized_protein_LOC105841576_isoform_X3_[Bombyx_mori]

Location

Bomo_Chr7(-):11746865-11747629      View in EpiBrowser

Full name

Transcription elongation factor spt6      

Location in the cell

Nuclear   Reliability : 2.203

CDS

ATGAGTGAGGATAAGCGTGAACGCAGTCCTAATTGGCTGTCGTCTGAAAAGGAACTTCTGTTGAGCCTAGTTAAATTTCATTTTAATATTATAGAAAAAAAAAAAACTGATGGAATGACTATAAAATCAAAATTAGCTCAGTGGCAAATTATTGCAGACCAGTACAGTAGTCTAACAAGCCACTGCTTTCGCACAGCAGAAAACCTAAAAGCCCAGTGGGAGAGTATGAAAAAGGTATCTAGAAAAGATGCAGCAAATAATAGGAGACATATGATTCAAACAGGAGTTGGATCCCCTATACCTCCCTTCAGCAGATCTTATGCCTAA

Protein

MSEDKRERSPNWLSSEKELLLSLVKFHFNIIEKKKTDGMTIKSKLAQWQIIADQYSSLTSHCFRTAENLKAQWESMKKVSRKDAANNRRHMIQTGVGSPIPPFSRSYA

Description

Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII).

Similarity

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
Belongs to the SPT6 family.

Uniprot

A0A2A4J6K5   A0A2P8Z2G3   A0A2P8XY57   E1ZZ26   A0A146LEA5   A0A151WIR4   + More
U4TYE9   A0A1Y1M9S1   A0A0A9X2W7   A0A146LYD6   A0A034WVI1   J9KJS7   A0A151IKX4   A0A0A9WAW2   A0A2A4ISV6   A0A1I8Q2D2   A0A2P8YD17   A0A1I8Q2E3   K1PK06   A0A2P8ZDU7   X1WKB7   E2AZH6   J9KQ47   A0A0L0BU16   A0A2P8ZCD3   E2BQ58   N6UWE6   J9M2M0   A0A3S2PJN2   A0A1Y1L814   A0A0T6BBT5   A0A151ICL3   J9L796   A0A1Y1KEI1   A0A151IJ96   A0A2H1VD05   N6TYS3   U4UHS3   A0A0A9WJX7   A0A1Y1KF23   A0A151J7U4   A0A2H1WJI6   J9KQ93   A0A194PCD7   J9JYM4   X1X5R7   A0A1Y1KC08   X1X4K4   D6WYB3   A0A151IG11   A0A2P8YV85   A0A2P8Y1Y6   A0A2W1BHL8   A0A1B6KKS9   J9M2S8   A0A2S2P4J3   J9KPC5   A0A293MPP4   A0A2P8Y9Q8   A0A0N1PGN5   A0A2S2PCE4   N6UKV0   J9L5Q5   A0A151I920   A0A2P8XX05  

Pubmed

29403074    20798317    26823975    23537049    28004739    25401762    + More
25348373    22992520    26108605    26354079    18362917    19820115    28756777   

EMBL

NWSH01003045    PCG67053.1    PYGN01000225    PSN50687.1    PYGN01001175    PSN36916.1    + More
GL435281    EFN73545.1    GDHC01013789    JAQ04840.1    KQ983082    KYQ47716.1    KB631844    ERL86664.1    GEZM01036744    JAV82403.1    GBHO01029598    JAG14006.1    GDHC01007259    JAQ11370.1    GAKP01000767    JAC58185.1    ABLF02013863    KQ977156    KYN05248.1    GBHO01039991    JAG03613.1    NWSH01007929    PCG62749.1    PYGN01000695    PSN42126.1    JH819173    EKC21958.1    PYGN01000086    PSN54683.1    ABLF02063305    GL444220    EFN61163.1    ABLF02016037    ABLF02016039    ABLF02016042    ABLF02016045    ABLF02016048    ABLF02028150    ABLF02028154    ABLF02035674    ABLF02048192    ABLF02051718    JRES01001461    KNC22709.1    PYGN01000106    PSN54158.1    GL449698    EFN82177.1    APGK01005471    KB736254    ENN83232.1    ABLF02003707    RSAL01000013    RVE53390.1    GEZM01063891    GEZM01063890    JAV68931.1    LJIG01002150    KRT84790.1    KQ978039    KYM97815.1    ABLF02007025    ABLF02035483    ABLF02060628    GEZM01088688    JAV58015.1    KQ977392    KYN03087.1    ODYU01001704    SOQ38282.1    APGK01049518    APGK01049519    KB741156    ENN73506.1    KB632169    ERL89425.1    GBHO01035525    JAG08079.1    GEZM01088687    JAV58016.1    KQ979672    KYN19878.1    ODYU01009057    SOQ53198.1    ABLF02036739    KQ459606    KPI90951.1    ABLF02011552    ABLF02033619    GEZM01088685    JAV58018.1    ABLF02033610    ABLF02059298    KQ971356    EFA09122.1    KQ977745    KYN00156.1    PYGN01000340    PSN48164.1    PYGN01001035    PSN38266.1    KZ150042    PZC74542.1    GEBQ01027927    JAT12050.1    ABLF02011053    GGMR01011721    MBY24340.1    ABLF02034348    GFWV01017160    MAA41888.1    PYGN01000772    PSN40997.1    KQ460556    KPJ13978.1    GGMR01014445    MBY27064.1    APGK01019740    APGK01019741    APGK01019742    KB740121    ENN81301.1    ABLF02017542    KQ978321    KYM95145.1    PYGN01001221    PSN36541.1   

Proteomes

UP000218220    UP000245037    UP000000311    UP000075809    UP000030742    UP000007819    + More
UP000078542    UP000095300    UP000005408    UP000037069    UP000008237    UP000019118    UP000283053    UP000078492    UP000053268    UP000007266    UP000053240   

Pfam

PF13873   Myb_DNA-bind_5        + More
PF10551   MULE
PF00225   Kinesin
PF13931   Microtub_bind
PF17674   HHH_9
PF14633   SH2_2
PF14639   YqgF
PF14641   HTH_44
PF14632   SPT6_acidic
PF14635   HHH_7
PF00575   S1

Interpro

IPR028002   Myb_DNA-bind_5        + More
IPR017877   Myb-like_dom       
IPR026753   NAIF1       
IPR001005   SANT/Myb       
IPR016187   CTDL_fold       
IPR026709   Msantd3       
IPR013083   Znf_RING/FYVE/PHD       
IPR001841   Znf_RING       
IPR018289   MULE_transposase_dom       
IPR011990   TPR-like_helical_dom_sf       
IPR026811   CIZ1       
IPR019734   TPR_repeat       
IPR013026   TPR-contain_dom       
IPR036961   Kinesin_motor_dom_sf       
IPR001752   Kinesin_motor_dom       
IPR027640   Kinesin-like_fam       
IPR019821   Kinesin_motor_CS       
IPR027417   P-loop_NTPase       
IPR025901   Kinesin-assoc_MT-bd_dom       
IPR042066   Spt6_death-like       
IPR035420   Spt6_SH2       
IPR036860   SH2_dom_sf       
IPR012340   NA-bd_OB-fold       
IPR017072   TF_Spt6       
IPR023319   Tex-like_HTH_dom_sf       
IPR032706   Spt6_HHH       
IPR010994   RuvA_2-like       
IPR012337   RNaseH-like_sf       
IPR035019   Spt6_SH2_N       
IPR028231   Spt6_YqgF       
IPR028083   Spt6_acidic_N_dom       
IPR003029   S1_domain       
IPR023323   Tex-like_dom_sf       
IPR037027   YqgF/RNaseH-like_dom_sf       
IPR035018   Spt6_SH2_C       
IPR041692   HHH_9       
IPR028088   Spt6_HTH_DNA-bd_dom       
IPR006641   YqgF/RNaseH-like_dom       
IPR022967   S1_dom       

SUPFAM

SSF56436   SSF56436        + More
SSF48452   SSF48452       
SSF52540   SSF52540       
SSF55550   SSF55550       
SSF50249   SSF50249       
SSF53098   SSF53098       
SSF47781   SSF47781       

Gene 3D

3.30.40.10     1.25.40.10     3.40.850.10     1.10.10.2740     1.10.10.650     1.10.3500.10     3.30.420.140     3.30.505.10    

CDD

cd00167  SANT
cd09928  SH2_Cterm_SPT6_like
cd09918  SH2_Nterm_SPT6_like

ProteinModelPortal

A0A2A4J6K5   A0A2P8Z2G3   A0A2P8XY57   E1ZZ26   A0A146LEA5   A0A151WIR4   + More
U4TYE9   A0A1Y1M9S1   A0A0A9X2W7   A0A146LYD6   A0A034WVI1   J9KJS7   A0A151IKX4   A0A0A9WAW2   A0A2A4ISV6   A0A1I8Q2D2   A0A2P8YD17   A0A1I8Q2E3   K1PK06   A0A2P8ZDU7   X1WKB7   E2AZH6   J9KQ47   A0A0L0BU16   A0A2P8ZCD3   E2BQ58   N6UWE6   J9M2M0   A0A3S2PJN2   A0A1Y1L814   A0A0T6BBT5   A0A151ICL3   J9L796   A0A1Y1KEI1   A0A151IJ96   A0A2H1VD05   N6TYS3   U4UHS3   A0A0A9WJX7   A0A1Y1KF23   A0A151J7U4   A0A2H1WJI6   J9KQ93   A0A194PCD7   J9JYM4   X1X5R7   A0A1Y1KC08   X1X4K4   D6WYB3   A0A151IG11   A0A2P8YV85   A0A2P8Y1Y6   A0A2W1BHL8   A0A1B6KKS9   J9M2S8   A0A2S2P4J3   J9KPC5   A0A293MPP4   A0A2P8Y9Q8   A0A0N1PGN5   A0A2S2PCE4   N6UKV0   J9L5Q5   A0A151I920   A0A2P8XX05  

KEGG

101742283    no KO assigned | (RefSeq) uncharacterized LOC101742283

GO

GO:0005634   GO:0006915   GO:0016021   GO:0003677   GO:0007018   GO:0008017   GO:0005524   GO:0003777   GO:0006139   GO:0032968   GO:0003746   GO:0003676   GO:0008270   GO:0004190   GO:0006508   GO:0042555   GO:0006260   GO:0004672   GO:0048384  

PANTHER

PTHR23098   PTHR21632   PTHR15491   PTHR24115   PTHR10145  

Subcellular location

Nucleus  

Length:

108

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00381

Exp number, first 60 AAs:

0.00236

Total prob of N-in:

0.41174

outside

1  -  108

 

 

Pi

122.521988

Theta

128.892862

Tajima's D

-0.156123

CLR

415.279984

CSRT

0.331533423328834

Interpretation

Uncertain