Gene

KWMTBOMO04078  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA008620

Annotation

mitochondria-associated_granulocyte_macrophage_CSF_signaling_molecule_[Bombyx_mori]

Location

Bomo_Chr7(-):10838711-10839265      View in EpiBrowser

Full name

Mitochondrial import inner membrane translocase subunit Tim16      

Alternative Name

Protein black pearl

Location in the cell

Mitochondrial   Reliability : 2.076

CDS

ATGGCTAAATACATAGCTCAGATAATAGTTTTGGGCGCTCAGGTTGTAGGTCGAGCATTCGCACGCGCCTTGAAACAAGAAATAGCTGCATCCCAAGAGGCAGCGAAGAGGGCTGGCGGTGGACCCGAAGGAGCGCGGAGAGCTGCTGCCAATGCTTCCACAGGGTTGACTTTAGAAGAAGCAATGCAAATATTAAATATAGAAAAAGTAGACCCCGAGAAAATTAGTAAAAATTATGAACACCTTTTCGCCGTAAACGACAAATCGAAAGGAGGTTCGTTTTATTTGCAATCGAAAATCGTAAGAGCGAAGGAGAGATTAGATGCGGAACTAAAACAAACATCACCCAACTCCGAGCAGGGCCCGTCTAAAGACACTTCATGA

Protein

MAKYIAQIIVLGAQVVGRAFARALKQEIAASQEAAKRAGGGPEGARRAAANASTGLTLEEAMQILNIEKVDPEKISKNYEHLFAVNDKSKGGSFYLQSKIVRAKERLDAELKQTSPNSEQGPSKDTS

Description

Regulates ATP-dependent protein translocation into the mitochondrial matrix (By similarity). Essential for larval development.

Subunit

Probable component of the PAM complex at least composed of a mitochondrial HSP70 protein, Roe1, TIM44, blp/TIM16 and TIM14. Associates with the TIM23 complex.

Similarity

Belongs to the TIM16/PAM16 family.

Keywords

Complete proteome   Developmental protein   Membrane   Mitochondrion   Mitochondrion inner membrane   Protein transport   Reference proteome   Translocation   Transport  

Feature

chain  Mitochondrial import inner membrane translocase subunit Tim16

Uniprot

Q2F5Q0   S4PCC2   A0A212EJ07   A0A0L7L7Q8   A0A2H1WAB1   A0A1E1W1Q0   + More
A0A194RLV9   I4DL66   A0A2A4K5G0   A0A1Q3FH70   A0A084VE30   A0A182RUB3   A0A182LG89   F5HKG0   A0A182HTV6   A0A182XHJ0   A0A182URS0   A0A182TVE8   Q16MR3   A0A182MCK3   A0A182N552   A0A182XV47   A0A182IZR4   A0A182VRM9   Q1HQE3   A0A182P634   A0A067QQF4   A0A182QWE2   B0W6A1   A0A182STU3   A0A2R7WGA8   A0A023EDV0   A0A1J1IFF8   E9GW89   A0A182K0T2   A0A182H6H1   W5JA28   A0A0K8TSW1   Q1W2C1   T1E812   A0A2M3ZBX7   A0A2M4C3E7   U5ERX3   A0A2M4ATE1   A0A1B6GK48   A0A1B6K750   A0A2J7RCM3   A0A0A9ZGU4   A0A0A1WRN5   B3M396   A0A2P8YL67   T1PGG9   A0A0P4XD61   A0A0L0CEC7   A0A0P6I6L0   A0A2R5LGJ0   A0A034WRI0   A0A0K8UAH3   A0A182FSF9   A0A1A9WJH9   B4LX95   A0A2G8KH97   A0A0B8RWM1   T1H650   W8BWP5   B4NB99   B4K5Q1   Q296P2   B4GEW1   A0A0P5MFY1   A0A023F8E8   A0A0B4LH72   Q9VF08   A0A0P5JN08   A0A232F2T9   K7J2B2   E9IAJ0   A0A3B4U888   B4JT54   A0A087U3V9   B4PRI4   B4HLG1   A0A3B0JQ86   A0A069DP86   A0A1I8PSC6   A0A1A9UTN2   B4QXS7   A0A0V0G686   A0A1S3ESV7   A0A3B4Z053   H3A7H4   A0A2I4BCR9   A0A1A9YK38   A0A1B0BBV4   F6ZIB8   D3ZZV1   A0A1A6GNU7   A0A1U7R642   A0A0P4VMK5   R4G3Q0  

Pubmed

19121390    23622113    22118469    26227816    26354079    22651552    + More
24438588    20966253    12364791    14747013    17210077    17510324    25244985    17204158    24845553    24945155    21292972    26483478    20920257    23761445    26369729    25401762    26823975    25830018    17994087    29403074    25315136    26108605    25348373    29023486    25476704    24495485    15632085    25474469    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    11179663    12537569    28648823    20075255    21282665    17550304    26334808    9215903    18464734    15057822    15632090    27129103   

EMBL

BABH01039421    DQ311373    ABD36317.1    GAIX01004251    JAA88309.1    AGBW02014538    + More
OWR41483.1    JTDY01002448    KOB71400.1    ODYU01007344    SOQ50025.1    GDQN01010137    JAT80917.1    KQ459995    KPJ18532.1    AK402034    KQ459600    BAM18656.1    KPI94295.1    NWSH01000139    PCG79154.1    GFDL01008161    JAV26884.1    ATLV01012223    KE524773    KFB36224.1    AAAB01008859    EGK96712.1    APCN01000586    CH477852    EAT35624.1    AXCM01004558    DQ440501    ABF18534.1    KK853575    KDR06593.1    AXCN02000174    DS231847    EDS36448.1    KK854784    PTY18692.1    GAPW01005825    JAC07773.1    CVRI01000048    CRK98997.1    GL732569    EFX76312.1    JXUM01027103    KQ560779    KXJ80926.1    ADMH02001856    ETN60846.1    GDAI01000387    JAI17216.1    DQ445506    GEBQ01018296    ABD98744.1    JAT21681.1    GAMD01002597    JAA98993.1    GGFM01005303    MBW26054.1    GGFJ01010638    MBW59779.1    GANO01002632    JAB57239.1    GGFK01010716    MBW44037.1    GECZ01006945    JAS62824.1    GECU01011760    GECU01000424    JAS95946.1    JAT07283.1    NEVH01005885    PNF38570.1    GBHO01022904    GBHO01000776    GBRD01003674    GDHC01019580    JAG20700.1    JAG42828.1    JAG62147.1    JAP99048.1    GBXI01012795    JAD01497.1    CH902617    EDV43557.1    PYGN01000517    PSN44991.1    KA647902    AFP62531.1    GDIP01245898    GDIQ01053134    JAI77503.1    JAN41603.1    JRES01000623    KNC29829.1    GDIQ01025782    JAN68955.1    GGLE01004452    MBY08578.1    GAKP01002162    JAC56790.1    GDHF01028637    JAI23677.1    CH940650    EDW66747.1    MRZV01000584    PIK47366.1    GBSH01002909    JAG66118.1    GAMC01002898    JAC03658.1    CH964232    EDW81063.1    CH933806    EDW15113.1    CM000070    EAL28415.1    CH479182    EDW34146.1    GDIQ01156191    JAK95534.1    GBBI01001132    JAC17580.1    AE014297    KX531789    AHN57348.1    ANY27599.1    AJ278732    AY071034    GDIQ01202575    JAK49150.1    NNAY01001181    OXU24829.1    AAZX01001589    GL762022    EFZ22410.1    CH916373    EDV94944.1    KK118034    KFM72048.1    CM000160    EDW97384.1    KRK03717.1    CH480815    EDW41981.1    OUUW01000008    SPP84285.1    GBGD01003462    JAC85427.1    CM000364    EDX12751.1    GECL01002598    JAP03526.1    AFYH01179811    AFYH01179812    AFYH01179813    AFYH01179814    AFYH01179815    JXJN01011707    AABR07029167    CH474017    EDL96294.1    LZPO01087157    OBS67037.1    GDKW01002909    JAI53686.1    ACPB03008412    GAHY01002030    JAA75480.1   

Proteomes

UP000005204    UP000007151    UP000037510    UP000053240    UP000053268    UP000218220    + More
UP000030765    UP000075900    UP000075882    UP000007062    UP000075840    UP000076407    UP000075903    UP000075902    UP000008820    UP000075883    UP000075884    UP000076408    UP000075880    UP000075920    UP000075885    UP000027135    UP000075886    UP000002320    UP000075901    UP000183832    UP000000305    UP000075881    UP000069940    UP000249989    UP000000673    UP000235965    UP000007801    UP000245037    UP000095301    UP000037069    UP000069272    UP000091820    UP000008792    UP000230750    UP000015102    UP000007798    UP000009192    UP000001819    UP000008744    UP000000803    UP000215335    UP000002358    UP000261420    UP000001070    UP000054359    UP000002282    UP000001292    UP000268350    UP000095300    UP000078200    UP000000304    UP000081671    UP000261360    UP000008672    UP000192220    UP000092443    UP000092460    UP000002279    UP000002494    UP000092124    UP000189706    UP000015103   

PRIDE

Q2F5Q0    Q9VF08    D3ZZV1   

Pfam

PF15052   TMEM169

Interpro

IPR036869   J_dom_sf        + More
IPR005341   Tim16       
IPR029386   TMEM169       

Gene 3D

1.10.287.110    

ProteinModelPortal

Q2F5Q0   S4PCC2   A0A212EJ07   A0A0L7L7Q8   A0A2H1WAB1   A0A1E1W1Q0   + More
A0A194RLV9   I4DL66   A0A2A4K5G0   A0A1Q3FH70   A0A084VE30   A0A182RUB3   A0A182LG89   F5HKG0   A0A182HTV6   A0A182XHJ0   A0A182URS0   A0A182TVE8   Q16MR3   A0A182MCK3   A0A182N552   A0A182XV47   A0A182IZR4   A0A182VRM9   Q1HQE3   A0A182P634   A0A067QQF4   A0A182QWE2   B0W6A1   A0A182STU3   A0A2R7WGA8   A0A023EDV0   A0A1J1IFF8   E9GW89   A0A182K0T2   A0A182H6H1   W5JA28   A0A0K8TSW1   Q1W2C1   T1E812   A0A2M3ZBX7   A0A2M4C3E7   U5ERX3   A0A2M4ATE1   A0A1B6GK48   A0A1B6K750   A0A2J7RCM3   A0A0A9ZGU4   A0A0A1WRN5   B3M396   A0A2P8YL67   T1PGG9   A0A0P4XD61   A0A0L0CEC7   A0A0P6I6L0   A0A2R5LGJ0   A0A034WRI0   A0A0K8UAH3   A0A182FSF9   A0A1A9WJH9   B4LX95   A0A2G8KH97   A0A0B8RWM1   T1H650   W8BWP5   B4NB99   B4K5Q1   Q296P2   B4GEW1   A0A0P5MFY1   A0A023F8E8   A0A0B4LH72   Q9VF08   A0A0P5JN08   A0A232F2T9   K7J2B2   E9IAJ0   A0A3B4U888   B4JT54   A0A087U3V9   B4PRI4   B4HLG1   A0A3B0JQ86   A0A069DP86   A0A1I8PSC6   A0A1A9UTN2   B4QXS7   A0A0V0G686   A0A1S3ESV7   A0A3B4Z053   H3A7H4   A0A2I4BCR9   A0A1A9YK38   A0A1B0BBV4   F6ZIB8   D3ZZV1   A0A1A6GNU7   A0A1U7R642   A0A0P4VMK5   R4G3Q0  

PDB

2GUZ     E-value=4.30651e-10,     Score=148

KEGG

692951    K17805 mitochondrial import inner membrane translocase subunit TIM16 | (RefSeq) mitochondria-associa

GO

GO:0005744   GO:0030150   GO:0008566   GO:0002168   GO:0016021   GO:0031314   GO:0001405   GO:0032780   GO:0001503   GO:0043066   GO:0090201   GO:1902511  

PANTHER

PTHR12388   PTHR31777  

Subcellular location

Mitochondrion inner membrane  

Length:

127

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.99922

Exp number, first 60 AAs:

0.99922

Total prob of N-in:

0.31184

outside

1  -  127

 

 

Pi

182.809554

Theta

194.393468

Tajima's D

-0.175787

CLR

43.479142

CSRT

0.322133893305335

Interpretation

Uncertain