Gene

KWMTBOMO04072

Annotation

hypothetical_protein_KGM_11869_[Danaus_plexippus]

Location

Bomo_Chr7(-):10662039-10671135      View in EpiBrowser

Full name

Guanylate cyclase      

Location in the cell

Extracellular   Reliability : 3.618

CDS

ATGTGGTTATCTGTGTTGCTAGTGGTGTGCGCGATCCCTTGGGGTGAATCGCAGAACTGCCGCGGGGAGAAACCTCGGCTCCGCGATTGCGATCGTCTCTGCGACAAGCAGGGCAACTGTAAGATCAAAGCTGCCCTACTTCTCCCGAAGAACATAACGTTCGGAGCGTGTATCGGTGCTGTGGAGCCAGTGTTGGAGCTGGCTATGCAGCATCCGGCGGTCCAGGATGCCTTTCCCTCGTGGGTCGGCTTCGAGTGGCAGACTTATGACGTCACAGATTGCGATGCAGCATATGCTGTCATTTCCGCCATCGACGCGTATAACGACTGCGCCCATGTCTTCCTCGGTCCCGCCTGTGATTTCGCATTAGGTGATTCTATTTGA

Protein

MWLSVLLVVCAIPWGESQNCRGEKPRLRDCDRLCDKQGNCKIKAALLLPKNITFGACIGAVEPVLELAMQHPAVQDAFPSWVGFEWQTYDVTDCDAAYAVISAIDAYNDCAHVFLGPACDFALGDSI

Catalytic Activity

GTP = 3',5'-cyclic GMP + diphosphate

Similarity

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Feature

chain  Guanylate cyclase

Uniprot

A0A2A4IZR6   A0A212FC87   A0A1E1WT37   A0A0L7LK13   A0A194PT40   A0A194RL17   + More
B4NBA5   A0A0C9QYW7   A0A2A3EEE4   A0A0A1X5Z0   A0A088AFH3   A0A151WKS9   B4LX88   A0A0C9PWJ7   A0A1W4VFG5   A0A195EDG4   A0A195F3D4   A0A0P9CAM4   B3P3W8   A0A310SF44   A0A158NDF8   A0A195B4Z8   Q9VF16   E9J769   F4W973   A0A0K8V105   W5JDF4   B4PRJ1   A0A232FFJ9   A0A151IFB5   A0A2M4CHA1   B4QXT3   B4HLG8   A0A0Q9XA14   K7J4N3   B4GEV3   Q296P8   A0A0L7QKR9   A0A026WAX4   A0A3B0KKH2   A0A154PID3   B4JT48   A0A1A9WJI8   E2B8H8   A0A182FSG2   A0A1B0BBW1   A0A1A9YK42   A0A1A9ZTC9   A0A1S4G740   E0VPJ2   A0A1B0G6S2   A0A182T9U6   A0A1B6MMP7   A0A182JED6   A0A182MJZ5   A0A1W4WJN3   A0A1W4W9J9   A0A1Y1M0M0   A0A336LM52   A0A0L8G872   D6W7W3  

EC Number

4.6.1.2

Pubmed

22118469    26227816    26354079    17994087    25830018    21347285    + More
10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    21282665    21719571    20920257    23761445    17550304    28648823    20075255    15632085    24508170    20798317    17510324    20566863    28004739    18362917    19820115   

EMBL

NWSH01004234    PCG65315.1    AGBW02009216    OWR51327.1    GDQN01000859    GDQN01000188    + More
JAT90195.1    JAT90866.1    JTDY01000846    KOB75684.1    KQ459600    KPI94300.1    KQ459995    KPJ18528.1    CH964232    EDW81069.2    GBYB01005872    JAG75639.1    KZ288287    PBC29381.1    GBXI01008204    JAD06088.1    KQ983002    KYQ48417.1    CH940650    EDW66740.2    GBYB01005873    JAG75640.1    KQ979039    KYN23265.1    KQ981855    KYN34896.1    CH902617    KPU80309.1    CH954181    EDV49074.1    KQ777939    OAD52020.1    ADTU01001012    KQ976598    KYM79571.1    AE014297    AAF55245.1    GL768421    EFZ11328.1    GL888002    EGI69255.1    GDHF01019720    JAI32594.1    ADMH02001856    ETN60844.1    CM000160    EDW97391.2    NNAY01000279    OXU29534.1    KQ977800    KYM99574.1    GGFL01000353    MBW64531.1    CM000364    EDX12757.1    CH480815    EDW41988.1    CH933806    KRG01393.1    AAZX01000467    CH479182    EDW34138.1    CM000070    EAL28409.3    KQ414940    KOC59165.1    KK107293    EZA53252.1    OUUW01000008    SPP84278.1    KQ434902    KZC11078.1    CH916373    EDV94938.1    GL446332    EFN88012.1    JXJN01011716    DS235366    EEB15298.1    CCAG010013864    GEBQ01002838    JAT37139.1    AXCM01003272    GEZM01047698    JAV76777.1    UFQT01000054    SSX19066.1    KQ423235    KOF73226.1    KQ971307    EFA11145.1   

Proteomes

UP000218220    UP000007151    UP000037510    UP000053268    UP000053240    UP000007798    + More
UP000242457    UP000005203    UP000075809    UP000008792    UP000192221    UP000078492    UP000078541    UP000007801    UP000008711    UP000005205    UP000078540    UP000000803    UP000007755    UP000000673    UP000002282    UP000215335    UP000078542    UP000000304    UP000001292    UP000009192    UP000002358    UP000008744    UP000001819    UP000053825    UP000053097    UP000268350    UP000076502    UP000001070    UP000091820    UP000008237    UP000069272    UP000092460    UP000092443    UP000092445    UP000009046    UP000092444    UP000075901    UP000075880    UP000075883    UP000192223    UP000053454    UP000007266   

PRIDE

Q9VF16   

Pfam

PF01094   ANF_receptor        + More
PF07714   Pkinase_Tyr
PF00211   Guanylate_cyc

Interpro

IPR028082   Peripla_BP_I        + More
IPR001828   ANF_lig-bd_rcpt       
IPR001170   ANPR/GUC       
IPR011009   Kinase-like_dom_sf       
IPR018297   A/G_cyclase_CS       
IPR001245   Ser-Thr/Tyr_kinase_cat_dom       
IPR029787   Nucleotide_cyclase       
IPR000719   Prot_kinase_dom       
IPR001054   A/G_cyclase       
IPR020635   Tyr_kinase_cat_dom       

SUPFAM

SSF53822   SSF53822        + More
SSF55073   SSF55073       
SSF56112   SSF56112       

Gene 3D

3.30.70.1230    

ProteinModelPortal

A0A2A4IZR6   A0A212FC87   A0A1E1WT37   A0A0L7LK13   A0A194PT40   A0A194RL17   + More
B4NBA5   A0A0C9QYW7   A0A2A3EEE4   A0A0A1X5Z0   A0A088AFH3   A0A151WKS9   B4LX88   A0A0C9PWJ7   A0A1W4VFG5   A0A195EDG4   A0A195F3D4   A0A0P9CAM4   B3P3W8   A0A310SF44   A0A158NDF8   A0A195B4Z8   Q9VF16   E9J769   F4W973   A0A0K8V105   W5JDF4   B4PRJ1   A0A232FFJ9   A0A151IFB5   A0A2M4CHA1   B4QXT3   B4HLG8   A0A0Q9XA14   K7J4N3   B4GEV3   Q296P8   A0A0L7QKR9   A0A026WAX4   A0A3B0KKH2   A0A154PID3   B4JT48   A0A1A9WJI8   E2B8H8   A0A182FSG2   A0A1B0BBW1   A0A1A9YK42   A0A1A9ZTC9   A0A1S4G740   E0VPJ2   A0A1B0G6S2   A0A182T9U6   A0A1B6MMP7   A0A182JED6   A0A182MJZ5   A0A1W4WJN3   A0A1W4W9J9   A0A1Y1M0M0   A0A336LM52   A0A0L8G872   D6W7W3  

KEGG

NA   

GO

GO:0016021   GO:0005524   GO:0035556   GO:0004383   GO:0004672   GO:0004713   GO:0007168   GO:0006182   GO:0007165   GO:0001653   GO:0005886  

SignalP

Position:   1 - 17,         Likelihood:  0.997326

 

 

Length:

127

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0750399999999999

Exp number, first 60 AAs:

0.05099

Total prob of N-in:

0.04800

outside

1  -  127

 

 

Pi

313.171678

Theta

175.025986

Tajima's D

2.775245

CLR

0.143218

CSRT

0.965551722413879

Interpretation

Uncertain