Gene

KWMTBOMO04064  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001051

Annotation

glutathione_S-transferase_epsilon_1_[Bombyx_mori]

Location

Bomo_Chr7(-):10295884-10303280      View in EpiBrowser

Full name

Glutathione S-transferase 1      

Alternative Name

GST class-theta

Location in the cell

Cytoplasmic   Reliability : 3.113

CDS

ATGGTGCTAACACTCTACAAGATGGACGCCAGTCCCCCAGTCCGCGCTGTCTACATGGTCATCGAAGCACTAAACATTCCCAACGTAAAATATGTAGACGTGGACCTCTTAGCTGAAGATCATTTGAAAGAGGAGTTCTTGAAGCTAAACCCTCAACACACCATTCCTATGCTGACAGATGACAAATTCGTCATCTGGGACAGTCATGCAATAGCTACATATTTGCTAAACAAATACGGCAAAGGCAGTTCATACTATCCCGAGGACCCAGAGAAGAGAGCCCTGATCGATATGAGATTACATTTCGACAGTGGAATATTGTATCCTGCTTTGCGAGAAAACGACGAGCCCATTTTCTTTTGGGGCGAGACCACCTTCAAGCCTCAAGGTCTGGCCAAAATAAAGTCAGCTTATGATTTCACGGAGAAGTTTCTTTCTGATTCACCGTGGATCGCAGGCGATGACGTCACTGTGGCTGATATGAGCTGTGTTGCTACAATCGGCAGTTTGGATGCGCTCTTGCCTATTAATGAGAAAGAGTATCCCAAGATAACTTCGTGGTTGAAACGCTGTTCTGAGCTAGACTTTTACCAGAGAGGAAACAACGTAAAAGGCCTATTGGAATTCAAGGCGTTACTGAAACAATACTTGAGTCGTGGAAAAGAATAA

Protein

MVLTLYKMDASPPVRAVYMVIEALNIPNVKYVDVDLLAEDHLKEEFLKLNPQHTIPMLTDDKFVIWDSHAIATYLLNKYGKGSSYYPEDPEKRALIDMRLHFDSGILYPALRENDEPIFFWGETTFKPQGLAKIKSAYDFTEKFLSDSPWIAGDDVTVADMSCVATIGSLDALLPINEKEYPKITSWLKRCSELDFYQRGNNVKGLLEFKALLKQYLSRGKE

Catalytic Activity

glutathione + RX = a halide anion + an S-substituted glutathione + H(+)

Subunit

Homodimer.

Similarity

Belongs to the GST superfamily.
Belongs to the GST superfamily. Theta family.

Keywords

Transferase  

Feature

chain  Glutathione S-transferase 1

Uniprot

Q86PP4   A0A3B0ERN2   A0A3G1ZLC3   A0A075X2W2   A0A2A4JI76   A0A0D3M5T7   + More
A0A3G1ZLC4   P46430   A0A075X3R8   A0A077DB43   A0A3G1RJ81   B0LKP4   A0A1W6I4K4   C8YL89   A0A3G1RJ71   A0A0K8TUZ9   A0A0K0XRM5   A0A0A7BYG1   A0A194R511   A0A212EWF1   A0A3S2LLI2   B0LB16   A0A2H1WMU8   A0A3G1ZLB5   H9JKP2   A0A212FPJ3   A0A075X250   A0A077D820   X5D048   A0A1P8L0S2   A0A194PT45   I4DRZ4   A0A1Y1K6Z7   H9JKP3   I4DQ12   B4J202   B4L947   B4LCA0   A0A1W4U4J0   A0A1L8EHK4   A0A1L8EHS3   A0A1Y1N675   A0A1Y1N945   B4P4E9   B4HNN1   A0A3B0JT17   A0A1A9Z7J5   B4NN03   D3TQP5   A1ZB72   B4HNN4   A0A1I8Q311   A0A0L0C9Y8   Q8MR33   B4NMZ5   B4P4F2   A0A0J9RFT5   B4L948   D6WFC4   A0A1I8P4U1   B4NN02   A0A1W4U585   D2D0D4   B4P4L9   B3NMS4   D6WCV8   B4QCE7   B4QCE3   A1ZB71   A0A1I8MAH9   A0A1A9VHV1   A0A3B0JRA5   B3NMS1   Q7JZM3   T1PG87   Q28YS6   A0A1I8MXR0   A0A3B0J7I3   A0A1I8MHG2   T1PDX5   B4P4F0   B4KM85   A0A1I8M6Z2   A0A1I8M6H7   B4GIX8   A0A1W4UG19   A0A139WLM6   B3NMS0   A0A1A9XX95   A0A0M5JBA5   A0A1Y1N4N8   B4HNN7   D6WCV7   B4HNN5   W8C6H4   Q9U796   A0A0M4RGU3   A0A0J9RFJ9   A0A1A9WI28  

EC Number

2.5.1.18

Pubmed

20364407    30319435    7742833    29912411    26017144    26198868    + More
26354079    22118469    23803169    19121390    22651552    28004739    17994087    17550304    20353571    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26457432    26108605    22936249    18362917    19820115    26487708    25315136    15632085    24495485   

EMBL

AY192575    DQ862465    AAO41719.1    ABI15774.1    RBVL01000267    RKO09898.1    + More
MH177594    AYM01166.1    KF482966    AIH07590.1    NWSH01001309    PCG71767.1    KJ468614    AIB07715.1    MH177591    AYM01163.1    L32091    KF482963    AIH07587.1    KM099182    AIL29312.1    MG879008    AWX68888.1    EU216542    ABY66599.1    KX500032    ARM39002.1    FJ546089    ACU09495.1    MG879007    AWX68887.1    GCVX01000117    JAI18113.1    KP938862    AKS40343.1    KC966932    AHV85206.1    KQ460685    KPJ12893.1    AGBW02011991    OWR45830.1    RSAL01000067    RVE49301.1    EF506489    AB738325    ABS56977.1    BAM76808.1    ODYU01009688    SOQ54296.1    MH177592    AYM01164.1    BABH01011849    AGBW02002757    OWR55620.1    KF482964    AIH07588.1    KM099185    AIL29315.1    KF929205    AHW45903.1    KX229711    APW77572.1    KQ459600    KPI94305.1    AK405339    BAM20684.1    GEZM01090627    JAV57232.1    AK403881    BAM20002.1    CH916366    EDV95927.1    CH933816    EDW17222.1    CH940647    EDW68745.1    GFDG01000651    JAV18148.1    GFDG01000650    JAV18149.1    GEZM01012401    JAV92958.1    GEZM01013073    JAV92776.1    CM000158    EDW91635.1    CH480816    EDW48450.1    OUUW01000001    SPP75871.1    CH964282    EDW85742.1    EZ423747    ADD20023.1    AE013599    AAF57695.1    EDW48453.1    JRES01000678    KNC29243.1    AY122149    AAM52661.1    EDW85734.1    EDW91638.1    CM002911    KMY94817.1    EDW17223.2    KQ971319    EFA00271.1    EDW85741.1    FJ233082    ACO83224.1    EDW91642.1    CH954179    EDV55078.1    KQ971311    EEZ98834.1    CM000362    EDX07671.1    KMY94824.1    EDX07667.1    KMY94820.1    AAF57696.1    SPP75876.1    EDV55075.1    AY071166    AAL48788.2    KA646898    AFP61527.1    CM000071    EAL25890.1    SPP75872.1    KA646899    AFP61528.1    EDW91636.1    CH933808    EDW08749.1    CH479183    EDW36396.1    KYB28850.1    EDV55074.1    CP012525    ALC44418.1    GEZM01013079    JAV92769.1    EDW48456.1    EEZ98835.1    EDW48454.1    GAMC01008536    JAB98019.1    AF147205    AAD54937.1    KR107238    ALF04573.1    KMY94823.1   

Proteomes

UP000276569    UP000218220    UP000053240    UP000007151    UP000283053    UP000005204    + More
UP000053268    UP000001070    UP000009192    UP000008792    UP000192221    UP000002282    UP000001292    UP000268350    UP000092445    UP000007798    UP000000803    UP000095300    UP000037069    UP000007266    UP000008711    UP000000304    UP000095301    UP000078200    UP000001819    UP000008744    UP000092443    UP000092553    UP000091820   

PRIDE

Q86PP4    B0LKP4    B0LB16    H9JKP2    H9JKP3    A1ZB72    + More
Q8MR33    A1ZB71    Q7JZM3   

Pfam

PF00043   GST_C        + More
PF13417   GST_N_3
PF14497   GST_C_3

Interpro

IPR036282   Glutathione-S-Trfase_C_sf        + More
IPR036249   Thioredoxin-like_sf       
IPR004046   GST_C       
IPR010987   Glutathione-S-Trfase_C-like       
IPR004045   Glutathione_S-Trfase_N       
IPR040079   Glutathione_S-Trfase       

SUPFAM

SSF47616   SSF47616        + More
SSF52833   SSF52833       

ProteinModelPortal

Q86PP4   A0A3B0ERN2   A0A3G1ZLC3   A0A075X2W2   A0A2A4JI76   A0A0D3M5T7   + More
A0A3G1ZLC4   P46430   A0A075X3R8   A0A077DB43   A0A3G1RJ81   B0LKP4   A0A1W6I4K4   C8YL89   A0A3G1RJ71   A0A0K8TUZ9   A0A0K0XRM5   A0A0A7BYG1   A0A194R511   A0A212EWF1   A0A3S2LLI2   B0LB16   A0A2H1WMU8   A0A3G1ZLB5   H9JKP2   A0A212FPJ3   A0A075X250   A0A077D820   X5D048   A0A1P8L0S2   A0A194PT45   I4DRZ4   A0A1Y1K6Z7   H9JKP3   I4DQ12   B4J202   B4L947   B4LCA0   A0A1W4U4J0   A0A1L8EHK4   A0A1L8EHS3   A0A1Y1N675   A0A1Y1N945   B4P4E9   B4HNN1   A0A3B0JT17   A0A1A9Z7J5   B4NN03   D3TQP5   A1ZB72   B4HNN4   A0A1I8Q311   A0A0L0C9Y8   Q8MR33   B4NMZ5   B4P4F2   A0A0J9RFT5   B4L948   D6WFC4   A0A1I8P4U1   B4NN02   A0A1W4U585   D2D0D4   B4P4L9   B3NMS4   D6WCV8   B4QCE7   B4QCE3   A1ZB71   A0A1I8MAH9   A0A1A9VHV1   A0A3B0JRA5   B3NMS1   Q7JZM3   T1PG87   Q28YS6   A0A1I8MXR0   A0A3B0J7I3   A0A1I8MHG2   T1PDX5   B4P4F0   B4KM85   A0A1I8M6Z2   A0A1I8M6H7   B4GIX8   A0A1W4UG19   A0A139WLM6   B3NMS0   A0A1A9XX95   A0A0M5JBA5   A0A1Y1N4N8   B4HNN7   D6WCV7   B4HNN5   W8C6H4   Q9U796   A0A0M4RGU3   A0A0J9RFJ9   A0A1A9WI28  

PDB

4PNG     E-value=9.4997e-49,     Score=485

KEGG

692684    K00799 glutathione S-transferase [EC:2.5.1.18] | (RefSeq) GSTe1, GST1; glutathione S-transferase eps

PATHWAY

00480    Glutathione metabolism - Bombyx mori (domestic silkworm)
00980    Metabolism of xenobiotics by cytochrome P450 - Bombyx mori (domestic silkworm)
00982    Drug metabolism - cytochrome P450 - Bombyx mori (domestic silkworm)
00983    Drug metabolism - other enzymes - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016740   GO:0004364   GO:0006749   GO:0005737   GO:0005515   GO:0016758   GO:0000166   GO:0016788   GO:0046872   GO:0006811   GO:0006032   GO:0016021   GO:0004672   GO:0048384  

Length:

222

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00513

Exp number, first 60 AAs:

0.00282

Total prob of N-in:

0.07351

outside

1  -  222

 

 

Pi

220.742089

Theta

166.181458

Tajima's D

1.045313

CLR

0.059696

CSRT

0.671566421678916

Interpretation

Uncertain