Gene

KWMTBOMO04061

Pre Gene Modal

BGIBMGA010094

Annotation

glutathione_S-transferase_epsilon_4_[Bombyx_mori]

Location

Bomo_Chr7(-):10270337-10276200      View in EpiBrowser

Full name

Glutathione S-transferase 1      

Alternative Name

GST class-theta

Location in the cell

Cytoplasmic   Reliability : 2.947

CDS

ATGGTACTTCACGAGCTCGGAATTTATGACGTGGAACTCATTGAAGTGAATCTGCCAGAAAGGGACCATCTGAAAGAAGAATTTCTGAGGATGAATCCGCAACACACTGTTCCCACGTTAATAGACGGAGATTTCATAATATGGGACAGCCACGCCATAGTCACATATTTGGTGAACAGATATGCTAAAAATGACACATTATATCCTAAAGAGCCTAAACAAAGAGCCATTGTTGATCAGAGGTTACATTTTGATACCGGAGTGCTCTTCGCCATATTACGAGCCACTGCTGAACCGGTATTATACAACAATGAAAAGAGCTTTAAACAAGAAAATCTAGAGAAAATGGAGGCAGCCTACGAATTCGTTGAAAAATTCCTGACTTCCGATTGGCTAGCCGGAGACCAAGTTACATTAGCCGATATCTGCTGTGTATCTACAATCAGTTCCATGAACGTAATTGTCCCTATTGACAAAAAGAAGTACCCAAAAATAATTTCATGGCTACAGCGCTGTTCCGAACAAGAATTTTACAAGAAAGCCAACGAACCAGGCTTGAAGAAATTCATAGAAATGTTCAAAAATAAAATCGGCAACTAA

Protein

MVLHELGIYDVELIEVNLPERDHLKEEFLRMNPQHTVPTLIDGDFIIWDSHAIVTYLVNRYAKNDTLYPKEPKQRAIVDQRLHFDTGVLFAILRATAEPVLYNNEKSFKQENLEKMEAAYEFVEKFLTSDWLAGDQVTLADICCVSTISSMNVIVPIDKKKYPKIISWLQRCSEQEFYKKANEPGLKKFIEMFKNKIGN

Catalytic Activity

glutathione + RX = a halide anion + an S-substituted glutathione + H(+)

Subunit

Homodimer.

Similarity

Belongs to the GST superfamily.
Belongs to the GST superfamily. Theta family.

Keywords

Transferase  

Feature

chain  Glutathione S-transferase 1

Uniprot

B0LB16   H9JKP3   A0A3G1ZLB5   A0A3G1RJ81   A0A075X250   A0A0K0XRM5   + More
A0A3G1RJ71   A0A077DB43   A0A3S2LLI2   A0A0D3M5T7   A0A2A4JI76   A0A077D820   A0A075X3R8   H9JKP2   A0A3G1ZLC4   A0A1W6I4K4   C8YL89   B0LKP4   A0A212FPJ3   P46430   A0A0A7BYG1   A0A0K8TUZ9   A0A212EWF1   A0A3B0ERN2   X5D048   A0A1P8L0S2   A0A3G1ZLC3   Q86PP4   A0A194R511   I4DQ12   A0A075X2W2   A0A2H1WRP7   A0A2H1WMU8   A0A194PT45   W5JBQ5   A0A0M4RGU3   D6WCV1   A0A1A9Z7F8   A0A1I8Q311   V5I823   A0A1A9V6B1   D6WCV4   T1PFR3   T1E824   A0A1I8MAH9   A0A1A9WI52   A0A084VMZ3   A0A1B0BW26   A0A1B0GC57   A0A182G0F4   A0A2M4ARP2   A0A1P8PEV6   A0A0K8TQ48   A0A077CXF1   A0A2M4CYI6   A0A1A9X9N5   D6WCV8   D3TPR9   I4DRZ4   A0A077CUU7   A0A3B0J7I3   A0A1Y1K6Z7   A0A3B0J2X5   A0A182S4T9   V5GSL4   A0A0L0CBD3   D6WCV7   A0A077CVX3   W8C6H4   A0A1Y9H1X9   B0XGK3   A0A182INN7   B3NMS1   A0A182IKS8   A0A182PZ39   Q28YS7   D6WFC4   B4QCE3   B4NN02   A0A139WLM6   G0XSZ8   B4J4D9   G0XSZ2   A0A2M3Z2M4   A0A068B0N1   B3MBA6   B3MBA7   A0A2R4FXF5   A0A1Y9HB55   A0A1I8NXB0   A0A1Q3FRS7   D6WCV9   A0A2M3Z2N8   B4GIX6   A1ZB72   A0A2M3Z2W1   A0A1W4UG19   A0A2M3ZGK7   B3MBA2   B4HNN4  

EC Number

2.5.1.18

Pubmed

23803169    19121390    30319435    29912411    26198868    22118469    + More
7742833    26017144    20364407    26354079    22651552    20920257    23761445    18362917    19820115    25315136    24438588    27742358    26369729    20353571    28004739    26108605    24495485    17994087    15632085    22936249    22206003    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26457432   

EMBL

EF506489    AB738325    ABS56977.1    BAM76808.1    BABH01011849    MH177592    + More
AYM01164.1    MG879008    AWX68888.1    KF482964    AIH07588.1    KP938862    AKS40343.1    MG879007    AWX68887.1    KM099182    AIL29312.1    RSAL01000067    RVE49301.1    KJ468614    AIB07715.1    NWSH01001309    PCG71767.1    KM099185    AIL29315.1    KF482963    AIH07587.1    MH177591    AYM01163.1    KX500032    ARM39002.1    FJ546089    ACU09495.1    EU216542    ABY66599.1    AGBW02002757    OWR55620.1    L32091    KC966932    AHV85206.1    GCVX01000117    JAI18113.1    AGBW02011991    OWR45830.1    RBVL01000267    RKO09898.1    KF929205    AHW45903.1    KX229711    APW77572.1    MH177594    AYM01166.1    AY192575    DQ862465    AAO41719.1    ABI15774.1    KQ460685    KPJ12893.1    AK403881    BAM20002.1    KF482966    AIH07590.1    ODYU01010553    SOQ55749.1    ODYU01009688    SOQ54296.1    KQ459600    KPI94305.1    ADMH02001962    ETN60209.1    KR107238    ALF04573.1    KQ971311    EEZ98838.1    GALX01005435    JAB63031.1    EEZ99066.1    KA647509    AFP62138.1    GAMD01002577    JAA99013.1    ATLV01014635    KE524975    KFB39337.1    JXJN01021583    JXJN01021584    CCAG010018997    GGFK01010109    MBW43430.1    KU522318    APX61037.1    GDAI01001335    JAI16268.1    KJ868740    AIL23541.1    GGFL01006216    MBW70394.1    EEZ98834.1    EZ423421    ADD19697.1    AK405339    BAM20684.1    KJ868734    AIL23535.1    OUUW01000001    SPP75872.1    GEZM01090627    JAV57232.1    SPP75874.1    GALX01003869    JAB64597.1    JRES01000655    KNC29542.1    EEZ98835.1    KJ868738    AIL23539.1    GAMC01008536    JAB98019.1    DS233036    EDS27667.1    CH954179    EDV55075.1    AXCP01008582    CM000071    EAL25891.2    KQ971319    EFA00271.1    CM000362    CM002911    EDX07667.1    KMY94820.1    CH964282    EDW85741.1    KYB28850.1    HQ418410    AEJ87244.1    CH916367    EDW01621.1    HQ418404    AEJ87238.1    GGFM01002020    MBW22771.1    KJ637332    AIC76455.1    CH902619    EDV36031.1    EDV36032.1    MF034820    AVT42186.1    AXCN02000826    GFDL01004734    JAV30311.1    EEZ98833.1    GGFM01002041    MBW22792.1    CH479183    EDW36394.1    AE013599    AAF57695.1    GGFM01002108    MBW22859.1    GGFM01006872    MBW27623.1    EDV36027.1    CH480816    EDW48453.1   

Proteomes

UP000005204    UP000283053    UP000218220    UP000007151    UP000276569    UP000053240    + More
UP000053268    UP000000673    UP000007266    UP000092445    UP000095300    UP000078200    UP000095301    UP000091820    UP000030765    UP000092460    UP000092444    UP000069272    UP000092443    UP000268350    UP000075900    UP000037069    UP000075884    UP000002320    UP000075880    UP000008711    UP000075885    UP000001819    UP000000304    UP000007798    UP000001070    UP000007801    UP000075886    UP000008744    UP000000803    UP000192221    UP000001292   

PRIDE

B0LB16    H9JKP3    H9JKP2    B0LKP4    Q86PP4    A1ZB72    + More

Pfam

PF00043   GST_C        + More
PF13417   GST_N_3
PF14497   GST_C_3
PF02798   GST_N

Interpro

IPR036282   Glutathione-S-Trfase_C_sf        + More
IPR036249   Thioredoxin-like_sf       
IPR004046   GST_C       
IPR010987   Glutathione-S-Trfase_C-like       
IPR004045   Glutathione_S-Trfase_N       
IPR040079   Glutathione_S-Trfase       

SUPFAM

SSF47616   SSF47616        + More
SSF52833   SSF52833       

ProteinModelPortal

B0LB16   H9JKP3   A0A3G1ZLB5   A0A3G1RJ81   A0A075X250   A0A0K0XRM5   + More
A0A3G1RJ71   A0A077DB43   A0A3S2LLI2   A0A0D3M5T7   A0A2A4JI76   A0A077D820   A0A075X3R8   H9JKP2   A0A3G1ZLC4   A0A1W6I4K4   C8YL89   B0LKP4   A0A212FPJ3   P46430   A0A0A7BYG1   A0A0K8TUZ9   A0A212EWF1   A0A3B0ERN2   X5D048   A0A1P8L0S2   A0A3G1ZLC3   Q86PP4   A0A194R511   I4DQ12   A0A075X2W2   A0A2H1WRP7   A0A2H1WMU8   A0A194PT45   W5JBQ5   A0A0M4RGU3   D6WCV1   A0A1A9Z7F8   A0A1I8Q311   V5I823   A0A1A9V6B1   D6WCV4   T1PFR3   T1E824   A0A1I8MAH9   A0A1A9WI52   A0A084VMZ3   A0A1B0BW26   A0A1B0GC57   A0A182G0F4   A0A2M4ARP2   A0A1P8PEV6   A0A0K8TQ48   A0A077CXF1   A0A2M4CYI6   A0A1A9X9N5   D6WCV8   D3TPR9   I4DRZ4   A0A077CUU7   A0A3B0J7I3   A0A1Y1K6Z7   A0A3B0J2X5   A0A182S4T9   V5GSL4   A0A0L0CBD3   D6WCV7   A0A077CVX3   W8C6H4   A0A1Y9H1X9   B0XGK3   A0A182INN7   B3NMS1   A0A182IKS8   A0A182PZ39   Q28YS7   D6WFC4   B4QCE3   B4NN02   A0A139WLM6   G0XSZ8   B4J4D9   G0XSZ2   A0A2M3Z2M4   A0A068B0N1   B3MBA6   B3MBA7   A0A2R4FXF5   A0A1Y9HB55   A0A1I8NXB0   A0A1Q3FRS7   D6WCV9   A0A2M3Z2N8   B4GIX6   A1ZB72   A0A2M3Z2W1   A0A1W4UG19   A0A2M3ZGK7   B3MBA2   B4HNN4  

PDB

4PNG     E-value=5.76888e-45,     Score=452

KEGG

100141440    K00799 glutathione S-transferase [EC:2.5.1.18] | (RefSeq) GSTe4, GST9, gste; glutathione S-transfera

PATHWAY

00480    Glutathione metabolism - Bombyx mori (domestic silkworm)
00980    Metabolism of xenobiotics by cytochrome P450 - Bombyx mori (domestic silkworm)
00982    Drug metabolism - cytochrome P450 - Bombyx mori (domestic silkworm)
00983    Drug metabolism - other enzymes - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0004364   GO:0016740   GO:0005737   GO:0006749   GO:0005515   GO:0016758   GO:0000166   GO:0016788   GO:0046872   GO:0006811   GO:0006032   GO:0016021   GO:0004672   GO:0048384  

Length:

199

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.26443

Exp number, first 60 AAs:

0.07517

Total prob of N-in:

0.03180

outside

1  -  199

 

 

Pi

270.791525

Theta

166.87303

Tajima's D

1.68255

CLR

0.315083

CSRT

0.828558572071396

Interpretation

Uncertain