Gene

KWMTBOMO04050

Pre Gene Modal

BGIBMGA010288

Annotation

UDP-glucosyltransferase_precursor_[Bombyx_mori]

Location

Bomo_Chr7(+):9729581-9741241      View in EpiBrowser

Full name

UDP-glucuronosyltransferase      

Location in the cell

Cytoplasmic   Reliability : 1.025

CDS

ATGATGCCGTTGTGGATCCTAGTTGTTCTTCTAACTTTCTCATACAGCGGGGCACATAAAATACTTGTGGTATTTCCACTACCGGAGCAGAGTCACGGTATCCTGGGAGCTAGATTCGTAAGGCACTTGCTGAACTATGGACACGAGGTAACATATATAACACCCTTTATCGAAAAGTATACGCATCCGAATCAACAACAGGTGGATGTGAGCCGTAACTTAAAGTTAATTCCAGAAAATCCAGTGAACTTAAGTTCATTGATAAGTAAAGAGGTCTCCGCACCAGGATTTACGGAAACAATGAATTTCATGAATTTGGTGGCGGTACAGACGCTGGAAAACGAAAACGTCCAAAAACTTCTGAAAAACCCAAATCTCGAATTCGATTTGGTTATACTCGAATGGAATTTTAGTGAACTGTTAGCGGGAATTGCCGCAGTATTCGATGTACCTTACATATGGGTGTCCAACTTGGAACCTCATTGGTTGATAGCACGATTGGCGGGAGAAAGTTTCAACCCTATATTCAATAGCAATATCCTATCGCCATATATCCCACCACTAAATCTGTATCAACGCGTAGAGGAGCTTTGGACGCAAATTACTTTTCATTTCCACATGTATTGGTATAACGACAGAATACAAAGAAATGATTATGAAAGATTCTTTGGAGATATCATTCGTATGAAAGGCCGAGAGTCTCCGTTGTTTGAGGAACTCAAACGCAACGGATCGTTCGTGTTAGGTAATTCGCATCTGGCCTTAGGACATGAAATGAGGTTTCCGAACAACTACAAGAACGTTGGAGGGTACCACGTTGATGAGGAGGTTAAGCCCTTGTCACCAAAATTAGAAAAACTGATGAATAACGCTGCAGATGGCGTCATTTACTTCAGTATGGGATCGAAGCTTAAAAGTGAAGATTTACCAGTCGACATCAAGAAAGGCCTCATGAAAATGTTTGGTGAATTAAAACAGACTGTGTTGTGGAAGCTCGATGATAAATCTATCGATCCTCCAAGTAATGTGCATATTTTTAAGCGAGTACCTCAACAGAGCTTGCTTGCACATTCAAAGTGCGTTCTTTTTATCACCCACGGCGGCATTCTCTCTACGATCGAAGCTGTACATTACGGGGTTCCAATCATTGGGATACCGGCGTACGGCGATCAATTCCTCAACATAGAAAGACTTGTAAGGAAGGATCAGGCTAAGCGAGTTGATCTATCACACTCTTTAGTTGCTGACCTGAAGTATGCTATTGACGAACTTCTAAATACGAAACGGTACAACGACACAGCAAAGAACAACTCCTTTATTTTTACTCATCGTACCGTAAACGCTGGTGCCGAGATAGTTCACTGGGTTGAGCACGTGATCCTCACTAAGGGCGCCAAGTATCTCAGGACCGAGAATCTGGATCTACATTGGTATCAAAAACTATATTTGGACTTAGGCATCGTTATTGCTGACATCGATAAGCATTTGAACACATTTGAACAAACTTTCGACTTAATGGGACAAGTGAAACGTATGAAATGA

Protein

MMPLWILVVLLTFSYSGAHKILVVFPLPEQSHGILGARFVRHLLNYGHEVTYITPFIEKYTHPNQQQVDVSRNLKLIPENPVNLSSLISKEVSAPGFTETMNFMNLVAVQTLENENVQKLLKNPNLEFDLVILEWNFSELLAGIAAVFDVPYIWVSNLEPHWLIARLAGESFNPIFNSNILSPYIPPLNLYQRVEELWTQITFHFHMYWYNDRIQRNDYERFFGDIIRMKGRESPLFEELKRNGSFVLGNSHLALGHEMRFPNNYKNVGGYHVDEEVKPLSPKLEKLMNNAADGVIYFSMGSKLKSEDLPVDIKKGLMKMFGELKQTVLWKLDDKSIDPPSNVHIFKRVPQQSLLAHSKCVLFITHGGILSTIEAVHYGVPIIGIPAYGDQFLNIERLVRKDQAKRVDLSHSLVADLKYAIDELLNTKRYNDTAKNNSFIFTHRTVNAGAEIVHWVEHVILTKGAKYLRTENLDLHWYQKLYLDLGIVIADIDKHLNTFEQTFDLMGQVKRMK

Catalytic Activity

glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + H(+) + UDP

Similarity

Belongs to the UDP-glycosyltransferase family.

Feature

chain  UDP-glucuronosyltransferase

Uniprot

D6RUU9   G9LPV0   G9LPU8   D6RUU6   A0A2H1VVH6   G9LPU6   + More
A0A2H1WNF9   A0A191T2G6   A0A2A4K2B6   G9LPU7   D6RUV0   A0A191T2J8   A0A2H4WB58   A0A2W1BVZ0   A0A2W1BXG7   G9LPQ0   G9LPQ1   A0A140EA36   A0A3S2LD93   D6RUU7   H9JL88   A0A2W1BQS6   A0A024AGG4   G9LPQ7   A0A191T2K2   A0A2A4K0I8   G9LPQ3   A0A024AHN0   A0A191T1M8   A0A3S2LTQ3   A0A2H4WB67   A0A194Q0G5   A0A024AH17   D0PWZ6   A0A2W1BQJ5   A0A191T1M6   A0A2H1V1W5   A0A2A4J419   A0A1L8D6H0   A0A194RKA9   Q8WPG4   A0A1L8D6R9   G9LPU0   A0A194Q5Q0   A0A2A4J6T0   A0A194RKU4   A0A2H1X1Y8   D6RUU8   A0A140EA37   G9LPQ6   D6RUV1   A0A191T1N5   A0A191T1M1   A0A0N1IN21   I4DN89   A0A0L7L1M9   A0A2H1W225   A0A191T1M3   G9LPU4   G9LPU3   A0A194R8C7   A0A3S2P0K8   D6RUV2   I4DR17   A0A2W1BX32   G9LPQ5   A0A2W1BSQ4   A0A2H4WB53   A0A191T2G9   A0A2A4J325   A0A3S2TLE9   A0A212FKT5   A0A3S2NJP8   A0A191T1P1   A0A194Q1C7   G9LPQ2   A0A2H1WQL3   A0A2H4WB78   G9LPU1   A0A024AG04   A0A2A4J0B4   H9JKP9   G9LPU2   A0A1L8D6E4   G9LPQ4   A0A2H1W5E5   A0A194RDA8   A0A191T2K0   A0A212FD09   A0A2H1VVH4   A0A0L7L448   A0A2W1BQJ6   A0A1L8D6G3   A0A212ERW0   A0A194Q4F3   A0A0N1INW2  

EC Number

2.4.1.17

Pubmed

20534444    22155036    29027758    28756777    26873292    19121390    + More
24698447    26354079    11846783    22651552    26227816    22118469   

EMBL

AB539966    BAJ08156.1    JQ070257    AEW43173.1    JQ070255    AEW43171.1    + More
AB539963    BAJ08153.1    ODYU01004685    SOQ44830.1    JQ070253    AEW43169.1    ODYU01009829    SOQ54516.1    KU680295    ANI22001.1    NWSH01000282    PCG77782.1    JQ070254    AEW43170.1    AB539967    BAJ08157.1    KU680294    ANI22000.1    KY202932    AUC64276.1    KZ149930    PZC77367.1    PZC77366.1    JQ070207    AEW43123.1    JQ070208    AEW43124.1    KU214507    AMK97473.1    RSAL01000210    RVE44216.1    JQ070252    AB539964    AEW43168.1    BAJ08154.1    BABH01011785    BABH01011786    BABH01011787    PZC77368.1    KF777115    AHY99686.1    JQ070214    AEW43130.1    KU680304    ANI22010.1    PCG77781.1    JQ070210    AEW43126.1    KF777113    AHY99684.1    KU680303    ANI22009.1    RVE44215.1    KY202937    AUC64281.1    KQ459582    KPI98793.1    KF777116    AHY99687.1    FJ373022    ACQ66003.1    PZC77369.1    KU680302    ANI22008.1    ODYU01000116    SOQ34342.1    NWSH01003535    PCG66153.1    GEYN01000076    JAV02053.1    KQ460075    KPJ17977.1    AF324465    AAL55994.1    GEYN01000085    JAV02044.1    JQ070247    AEW43163.1    KPI98725.1    NWSH01002698    PCG67661.1    KPJ17950.1    ODYU01012744    SOQ59206.1    AB539965    BAJ08155.1    KU214508    AMK97474.1    JQ070213    AEW43129.1    JQ070258    AB539968    AEW43174.1    BAJ08158.1    KU680296    ANI22002.1    KU680297    ANI22003.1    KQ459356    KPJ01283.1    AK402777    BAM19379.1    JTDY01003683    KOB69154.1    ODYU01005852    SOQ47145.1    KU680298    ANI22004.1    JQ070251    AEW43167.1    JQ070250    AEW43166.1    KQ460597    KPJ13897.1    RSAL01000067    RVE49310.1    JQ070256    AB539969    AEW43172.1    BAJ08159.1    AK404892    BAM20357.1    PZC77370.1    JQ070212    AEW43128.1    PZC77371.1    KY202925    AUC64269.1    KU680300    ANI22006.1    NWSH01003818    PCG65793.1    RVE49311.1    AGBW02007992    OWR54346.1    RVE49308.1    KU680301    ANI22007.1    KPI98794.1    JQ070209    AEW43125.1    ODYU01010264    SOQ55252.1    KY202946    AUC64290.1    JQ070248    AEW43164.1    KF777114    AHY99685.1    NWSH01003979    PCG65597.1    JQ070249    AEW43165.1    GEYN01000100    JAV02029.1    JQ070211    AEW43127.1    ODYU01006413    SOQ48233.1    KPJ13896.1    KU680299    ANI22005.1    AGBW02009118    OWR51610.1    SOQ44829.1    JTDY01003050    KOB70242.1    PZC77372.1    GEYN01000087    JAV02042.1    AGBW02012922    OWR44215.1    KQ459472    KPJ00229.1    KQ460784    KPJ12207.1   

Proteomes

UP000218220    UP000283053    UP000005204    UP000053268    UP000053240    UP000037510    + More
UP000007151   

PRIDE

D6RUU9    G9LPV0    G9LPU8    D6RUU6    G9LPU6    G9LPU7    + More
D6RUV0    D6RUU7    H9JL88    D0PWZ6    Q8WPG4    G9LPU0    D6RUU8    D6RUV1    G9LPU4    G9LPU3    D6RUV2    G9LPU1    H9JKP9    G9LPU2   

Pfam

PF00201   UDPGT

Interpro

IPR002213   UDP_glucos_trans        + More
IPR035595   UDP_glycos_trans_CS       

ProteinModelPortal

D6RUU9   G9LPV0   G9LPU8   D6RUU6   A0A2H1VVH6   G9LPU6   + More
A0A2H1WNF9   A0A191T2G6   A0A2A4K2B6   G9LPU7   D6RUV0   A0A191T2J8   A0A2H4WB58   A0A2W1BVZ0   A0A2W1BXG7   G9LPQ0   G9LPQ1   A0A140EA36   A0A3S2LD93   D6RUU7   H9JL88   A0A2W1BQS6   A0A024AGG4   G9LPQ7   A0A191T2K2   A0A2A4K0I8   G9LPQ3   A0A024AHN0   A0A191T1M8   A0A3S2LTQ3   A0A2H4WB67   A0A194Q0G5   A0A024AH17   D0PWZ6   A0A2W1BQJ5   A0A191T1M6   A0A2H1V1W5   A0A2A4J419   A0A1L8D6H0   A0A194RKA9   Q8WPG4   A0A1L8D6R9   G9LPU0   A0A194Q5Q0   A0A2A4J6T0   A0A194RKU4   A0A2H1X1Y8   D6RUU8   A0A140EA37   G9LPQ6   D6RUV1   A0A191T1N5   A0A191T1M1   A0A0N1IN21   I4DN89   A0A0L7L1M9   A0A2H1W225   A0A191T1M3   G9LPU4   G9LPU3   A0A194R8C7   A0A3S2P0K8   D6RUV2   I4DR17   A0A2W1BX32   G9LPQ5   A0A2W1BSQ4   A0A2H4WB53   A0A191T2G9   A0A2A4J325   A0A3S2TLE9   A0A212FKT5   A0A3S2NJP8   A0A191T1P1   A0A194Q1C7   G9LPQ2   A0A2H1WQL3   A0A2H4WB78   G9LPU1   A0A024AG04   A0A2A4J0B4   H9JKP9   G9LPU2   A0A1L8D6E4   G9LPQ4   A0A2H1W5E5   A0A194RDA8   A0A191T2K0   A0A212FD09   A0A2H1VVH4   A0A0L7L448   A0A2W1BQJ6   A0A1L8D6G3   A0A212ERW0   A0A194Q4F3   A0A0N1INW2  

PDB

2O6L     E-value=8.44017e-18,     Score=223

KEGG

100500763    K00699 glucuronosyltransferase [EC:2.4.1.17] | (RefSeq) UGT10288, UGT40P1; UDP-glucosyltransferase

PATHWAY

00040    Pentose and glucuronate interconversions - Bombyx mori (domestic silkworm)
00053    Ascorbate and aldarate metabolism - Bombyx mori (domestic silkworm)
00830    Retinol metabolism - Bombyx mori (domestic silkworm)
00860    Porphyrin and chlorophyll metabolism - Bombyx mori (domestic silkworm)
00980    Metabolism of xenobiotics by cytochrome P450 - Bombyx mori (domestic silkworm)
00982    Drug metabolism - cytochrome P450 - Bombyx mori (domestic silkworm)
00983    Drug metabolism - other enzymes - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016021   GO:0016758   GO:0015020   GO:0016740   GO:0008152   GO:0006355   GO:0005524   GO:0007179   GO:0006811   GO:0006032   GO:0004672   GO:0048384  

Subcellular location

Membrane  

SignalP

Position:   1 - 18,         Likelihood:  0.983474

 

 

Length:

513

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

9.29016999999996

Exp number, first 60 AAs:

8.97040999999999

Total prob of N-in:

0.39176

outside

1  -  513

 

 

Pi

176.827973

Theta

141.494739

Tajima's D

1.218066

CLR

0.070585

CSRT

0.71656417179141

Interpretation

Uncertain