Gene

KWMTBOMO04047

Pre Gene Modal

BGIBMGA010286

Annotation

PREDICTED:_UDP-glucosyltransferase_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr7(+):9671921-9692709      View in EpiBrowser

Full name

UDP-glucuronosyltransferase      

Location in the cell

Peroxisomal   Reliability : 1.101 PlasmaMembrane   Reliability : 1.288

CDS

ATGTTCAAGCTCACATTCCTGGTCTGCTGTATCCTGGCTACTCAATCCGTTTCTGATGCCTATAAAATCCTGGTGGTGTTCCCTATGCCCGGCAAAAGCCACAGTATCCTGGGGTACAGTGTCGTGAAGCATCTCCTAAAAGCTGGTCATGAGGTGACATATGTAACTCCTTTCGTTGAGGACAATCACCACCCGAACCTGACTCAAGTTGATGTTAGCAGCAATATGCGTTTGATACCTAAGGGCGGATTAGACTTGAAGAGAGTTCTAGACAAAGAGGTAAACGTAATAGACAACGGGTTTATGTTTTATTTCATGAAACAAATACAGGAAGCTACTCTGGAGCATGAGCAAGTTAAAAAGTTGCTCGAGGACCCGAATAAGACCTTCGATATTGTTATCGTTGAGTGGATGTATTGCGAATTGGGTGCTAGTTATGCTGCGGTATTCGACGTTCCACTTATATGGTTGTCGACCATGGAGCCTCACTGGTTGGTGACGAGGCTCATCGATGGGAATCTAAATCCAGCCTACAACGGGGATTCTATGTCTTCCAGTATTCCTCCATTTACGTTCTTGCAAAGAGTCAAGGAACTCTGGATTCAAATTCACACTAGTTTTATATTGCTCAATGATGATCAAGAGAGATCGTACGACAGATTAGTGAGGCCACTCATTGAAAAAAAAGGTAGGAAGGCGCCTTCGTTTGAGGATTTGAAGTTCAATGCTTCTTTAGTACTCGGAAATTCGCATGTATCTTTGGGAGAAGCAACCGGAACTCCGCAGAGCTACAAACCCATCGCTGGATACCATATAGAAGAAGTTGTGAAACCTTTACCAGCTGACCTCAAAGAGATAATGGAAAACGCAAAGCACGGTGTCATCTATTTCAGTATGGGATCAAATTTGAAGAGTACAGAAATGCCAGATGAGATGAAGCAGAATCTTGTAAAAATGTTCGGTGAATTGAAACAGACTATTATCTGGAAGTTTGAAGAAGACTTCCCGAATCTCCCGAAAAACGTCCACATCGTAAATTGGGCACCACAACCAAGTATTTTATCTCATCCTAATTGCGTGTTATTCATCACACACGGAGGTCTACTTTCAACGACCGAAAGCGTACATTTTGGAGTGCCAATTGTGGGAATACCAGTTTTTGGTGATCAATTTATCAATGTCCAAAGGGCTGTTAAAAGGGGATTCGCGAAGAAAGTTGATTTCTCGTACTCAATGGTCGGAGAACTTAAGGTCGCTATTCAAGAAATTTTAAGTGACTCCAGCTACAGAACCAGAATTAAGGAGCTATCGTTGATATATCACGATCGTCCGGTGTCTCCTGGTGCCGAGCTGGTGCATTGGGTTGAGCACGTGGCCAGGACAAGAGGAGCTCTCCATCTGCGCTCACCAGCACTGCACGTGCCTTTCTACCAGAAGTTGTACTTAGATCTATTGGCCGTTGTATTAATAATTTCGCTAATCTTTTATAGAAAAATTTGTTTGATAAAAAATCTTTTACTGTCATTTTTTCAAACAAATGAAATCAAGAAGAAAAAGAAGAGGAATTAA

Protein

MFKLTFLVCCILATQSVSDAYKILVVFPMPGKSHSILGYSVVKHLLKAGHEVTYVTPFVEDNHHPNLTQVDVSSNMRLIPKGGLDLKRVLDKEVNVIDNGFMFYFMKQIQEATLEHEQVKKLLEDPNKTFDIVIVEWMYCELGASYAAVFDVPLIWLSTMEPHWLVTRLIDGNLNPAYNGDSMSSSIPPFTFLQRVKELWIQIHTSFILLNDDQERSYDRLVRPLIEKKGRKAPSFEDLKFNASLVLGNSHVSLGEATGTPQSYKPIAGYHIEEVVKPLPADLKEIMENAKHGVIYFSMGSNLKSTEMPDEMKQNLVKMFGELKQTIIWKFEEDFPNLPKNVHIVNWAPQPSILSHPNCVLFITHGGLLSTTESVHFGVPIVGIPVFGDQFINVQRAVKRGFAKKVDFSYSMVGELKVAIQEILSDSSYRTRIKELSLIYHDRPVSPGAELVHWVEHVARTRGALHLRSPALHVPFYQKLYLDLLAVVLIISLIFYRKICLIKNLLLSFFQTNEIKKKKKRN

Catalytic Activity

glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + H(+) + UDP

Similarity

Belongs to the UDP-glycosyltransferase family.

Feature

chain  UDP-glucuronosyltransferase

Uniprot

G9LPU8   D6RUU6   G9LPU6   D6RUU7   A0A2H1VVH6   A0A2W1BQS6   + More
A0A2A4K0I8   A0A024AGG4   A0A2H1WNF9   G9LPQ7   A0A2A4K2B6   G9LPU7   D6RUV0   H9JL88   A0A191T2J8   A0A2W1BXG7   G9LPQ0   A0A191T2G6   A0A2W1BVZ0   Q8WPG4   A0A191T1M8   A0A140EA36   A0A3S2LD93   G9LPQ1   G9LPU0   A0A2H4WB58   A0A024AH17   A0A191T2K2   A0A2H4WB67   A0A0L7L1M9   A0A024AHN0   A0A191T1N5   A0A1L8D6H0   D6RUU8   A0A2H1X1Y8   G9LPQ3   A0A2H1W225   A0A3S2LTQ3   D0PWZ6   A0A1L8D6R9   A0A2W1BQJ5   A0A2A4J419   A0A191T1M6   A0A191T1M1   A0A194RKU4   A0A2H1V1W5   G9LPQ6   A0A140EA37   A0A194Q0G5   D6RUV2   A0A194Q5Q0   A0A194RKA9   G9LPV0   D6RUU9   A0A2A4J6T0   A0A191T1M3   G9LPU3   G9LPQ5   A0A2W1BX32   A0A2W1BSQ4   I4DN89   A0A3S2NJP8   A0A0N1IN21   A0A191T2G9   A0A194R8C7   A0A3S2P0K8   A0A2A4J325   G9LPU4   A0A212FKT5   A0A2H1WQL3   A0A191T1P1   I4DR17   A0A2H4WB78   H9JKP9   A0A3S2TLE9   A0A1L8D6E4   G9LPQ2   A0A2H4WB53   A0A024AG04   A0A191T2K0   D6RUV1   A0A2A4J0B4   A0A2H1VVH4   A0A194RDA8   A0A194Q1C7   G9LPU2   G9LPQ4   A0A212FD09   A0A2H1W5E5   G9LPU1   A0A2W1BQJ6   A0A0L7L448   A0A212ERW0   A0A1L8D6G3  

EC Number

2.4.1.17

Pubmed

22155036    20534444    28756777    24698447    19121390    11846783    + More
26873292    29027758    26227816    26354079    22651552    22118469   

EMBL

JQ070255    AEW43171.1    AB539963    BAJ08153.1    JQ070253    AEW43169.1    + More
JQ070252    AB539964    AEW43168.1    BAJ08154.1    ODYU01004685    SOQ44830.1    KZ149930    PZC77368.1    NWSH01000282    PCG77781.1    KF777115    AHY99686.1    ODYU01009829    SOQ54516.1    JQ070214    AEW43130.1    PCG77782.1    JQ070254    AEW43170.1    AB539967    BAJ08157.1    BABH01011785    BABH01011786    BABH01011787    KU680294    ANI22000.1    PZC77366.1    JQ070207    AEW43123.1    KU680295    ANI22001.1    PZC77367.1    AF324465    AAL55994.1    KU680303    ANI22009.1    KU214507    AMK97473.1    RSAL01000210    RVE44216.1    JQ070208    AEW43124.1    JQ070247    AEW43163.1    KY202932    AUC64276.1    KF777116    AHY99687.1    KU680304    ANI22010.1    KY202937    AUC64281.1    JTDY01003683    KOB69154.1    KF777113    AHY99684.1    KU680296    ANI22002.1    GEYN01000076    JAV02053.1    AB539965    BAJ08155.1    ODYU01012744    SOQ59206.1    JQ070210    AEW43126.1    ODYU01005852    SOQ47145.1    RVE44215.1    FJ373022    ACQ66003.1    GEYN01000085    JAV02044.1    PZC77369.1    NWSH01003535    PCG66153.1    KU680302    ANI22008.1    KU680297    ANI22003.1    KQ460075    KPJ17950.1    ODYU01000116    SOQ34342.1    JQ070213    AEW43129.1    KU214508    AMK97474.1    KQ459582    KPI98793.1    JQ070256    AB539969    AEW43172.1    BAJ08159.1    KPI98725.1    KPJ17977.1    JQ070257    AEW43173.1    AB539966    BAJ08156.1    NWSH01002698    PCG67661.1    KU680298    ANI22004.1    JQ070250    AEW43166.1    JQ070212    AEW43128.1    PZC77370.1    PZC77371.1    AK402777    BAM19379.1    RSAL01000067    RVE49308.1    KQ459356    KPJ01283.1    KU680300    ANI22006.1    KQ460597    KPJ13897.1    RVE49310.1    NWSH01003818    PCG65793.1    JQ070251    AEW43167.1    AGBW02007992    OWR54346.1    ODYU01010264    SOQ55252.1    KU680301    ANI22007.1    AK404892    BAM20357.1    KY202946    AUC64290.1    RVE49311.1    GEYN01000100    JAV02029.1    JQ070209    AEW43125.1    KY202925    AUC64269.1    KF777114    AHY99685.1    KU680299    ANI22005.1    JQ070258    AB539968    AEW43174.1    BAJ08158.1    NWSH01003979    PCG65597.1    SOQ44829.1    KPJ13896.1    KPI98794.1    JQ070249    AEW43165.1    JQ070211    AEW43127.1    AGBW02009118    OWR51610.1    ODYU01006413    SOQ48233.1    JQ070248    AEW43164.1    PZC77372.1    JTDY01003050    KOB70242.1    AGBW02012922    OWR44215.1    GEYN01000087    JAV02042.1   

Proteomes

UP000218220    UP000005204    UP000283053    UP000037510    UP000053240    UP000053268    + More
UP000007151   

PRIDE

G9LPU8    D6RUU6    G9LPU6    D6RUU7    G9LPU7    D6RUV0    + More
H9JL88    Q8WPG4    G9LPU0    D6RUU8    D0PWZ6    D6RUV2    G9LPV0    D6RUU9    G9LPU3    G9LPU4    H9JKP9    D6RUV1    G9LPU2    G9LPU1   

Pfam

PF00201   UDPGT

Interpro

IPR035595   UDP_glycos_trans_CS        + More
IPR002213   UDP_glucos_trans       

ProteinModelPortal

G9LPU8   D6RUU6   G9LPU6   D6RUU7   A0A2H1VVH6   A0A2W1BQS6   + More
A0A2A4K0I8   A0A024AGG4   A0A2H1WNF9   G9LPQ7   A0A2A4K2B6   G9LPU7   D6RUV0   H9JL88   A0A191T2J8   A0A2W1BXG7   G9LPQ0   A0A191T2G6   A0A2W1BVZ0   Q8WPG4   A0A191T1M8   A0A140EA36   A0A3S2LD93   G9LPQ1   G9LPU0   A0A2H4WB58   A0A024AH17   A0A191T2K2   A0A2H4WB67   A0A0L7L1M9   A0A024AHN0   A0A191T1N5   A0A1L8D6H0   D6RUU8   A0A2H1X1Y8   G9LPQ3   A0A2H1W225   A0A3S2LTQ3   D0PWZ6   A0A1L8D6R9   A0A2W1BQJ5   A0A2A4J419   A0A191T1M6   A0A191T1M1   A0A194RKU4   A0A2H1V1W5   G9LPQ6   A0A140EA37   A0A194Q0G5   D6RUV2   A0A194Q5Q0   A0A194RKA9   G9LPV0   D6RUU9   A0A2A4J6T0   A0A191T1M3   G9LPU3   G9LPQ5   A0A2W1BX32   A0A2W1BSQ4   I4DN89   A0A3S2NJP8   A0A0N1IN21   A0A191T2G9   A0A194R8C7   A0A3S2P0K8   A0A2A4J325   G9LPU4   A0A212FKT5   A0A2H1WQL3   A0A191T1P1   I4DR17   A0A2H4WB78   H9JKP9   A0A3S2TLE9   A0A1L8D6E4   G9LPQ2   A0A2H4WB53   A0A024AG04   A0A191T2K0   D6RUV1   A0A2A4J0B4   A0A2H1VVH4   A0A194RDA8   A0A194Q1C7   G9LPU2   G9LPQ4   A0A212FD09   A0A2H1W5E5   G9LPU1   A0A2W1BQJ6   A0A0L7L448   A0A212ERW0   A0A1L8D6G3  

PDB

2O6L     E-value=1.2326e-25,     Score=290

KEGG

100500754    K00699 glucuronosyltransferase [EC:2.4.1.17] | (RefSeq) UGT10286, UGT40K1; UDP-glucosyltransferase

PATHWAY

00040    Pentose and glucuronate interconversions - Bombyx mori (domestic silkworm)
00053    Ascorbate and aldarate metabolism - Bombyx mori (domestic silkworm)
00830    Retinol metabolism - Bombyx mori (domestic silkworm)
00860    Porphyrin and chlorophyll metabolism - Bombyx mori (domestic silkworm)
00980    Metabolism of xenobiotics by cytochrome P450 - Bombyx mori (domestic silkworm)
00982    Drug metabolism - cytochrome P450 - Bombyx mori (domestic silkworm)
00983    Drug metabolism - other enzymes - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0015020   GO:0016021   GO:0016758   GO:0016740   GO:0008152   GO:0006355   GO:0005524   GO:0007179   GO:0006811   GO:0006032   GO:0004672   GO:0048384  

Subcellular location

Membrane  

SignalP

Position:   1 - 20,         Likelihood:  0.993325

 

 

Length:

522

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

22.52149

Exp number, first 60 AAs:

0.61798

Total prob of N-in:

0.03002

outside

1  -  473

TMhelix

474  -  496

inside

497  -  522

 

 

Pi

25.273633

Theta

23.402756

Tajima's D

0.698552

CLR

120.424005

CSRT

0.581270936453177

Interpretation

Uncertain