Silkworm Genome Informatics Database

Gene

KWMTBOMO04035

Pre Gene Modal

BGIBMGA010280

Annotation

PREDICTED:_tight_junction_protein_ZO-1_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr7(+):9521831-9546645 View in EpiBrowser

Location in the cell

Nuclear Reliability : 4.013

CDS

ATGTTTAAAAGTATTAAGAAGTTCGTCTTCGGCGTCGTCGCTGCATTCCTTTTAGATTGGCAGACTACTTACTATACGACCGCAGAACGCAGCACTGGCTGGGAGACGCATCGTGTGCGCTTGAACCGAGTGCAAGGATACGGCTTCGGCATTGCTGTGTCTGGAGGGAGAGACAATCCTCACTTCGCGAGTGGAGATCCCTCTATAGCAGTGTCGGATGTGTTACGCGGTGGTCCCGCTGAGGATAAACTCCAGGTGAATGACAGGATTGTCTCTGTGAACGGCGTGTCCCTTGAGAACGTGGAGTATGCGCGTGCTGTACAGGTACTGCGGGATTCGGGCGCGGCTGTGTCACTGGTGGTTCGACGGAGAGCTCCAGCGCCACCACCCACTGCTCCCACCACCATTAAACTAGCCCTCTCTAGGAATGGGAAGAAAGAAGATTTCGGAGTCGTACTTGGATGTAAATTGTATATAAAAGAGTTAACGATGAGAGCAAGAGAACAGCTGAACCAAAATGGGCAAGGCCTATGTGAGGGCGACGTCATATCGAGGATTAATAATACGCCTGTAACTGATGCTATGACACTGAAAGAGGCCAGAAAATTAGTGGAATCTTGTAAGGACAGACTGAACTTGGTCGTGACCAGAGAACTAATAAGAGAAGAAACGGTCACGAATGGGAACTATCAGAACAATTACAGTAGTTTAGATGCTCCGTCCCATAACGTGTATCCTGGGGCCGAACCGTTGTCTCCGGCGTATTCTAGCAGCGGACAGAACTTGTACGTAGCGGCGCCGGTCAGGGGCGGCTCCGGCGACGCGAGGAGAGGACCGATGTCGCACGAAGTGGAACAGCCCCCGAGACCGCCGCCACCCAGAAATGACGATTACTACAGCAGCAGAAGACAGCTGTATGAAGAAGAAGCAATGAATCAAAGGAACAAACCACCGAGTGAACCAAGATTAATAAGTTTCCAAAAAGAGGGATCAGTAGGGTTGCGACTGTGCGGTGGTAATCGATCGGGTGTCTTCGTATCGGGAGTCCAACCGACCAGCCCTGCGGCGTTGCAGGGATTGCAACCAGCCGATAAAATACTGAAGGTCAACGACATGGAAATGAAAGGTGTTACCCGTGAAGAAGCAGTGCTGTTTCTATTGAGTTTACAAGATAGGATCGACCTCATAGTCCAACATTCGCCTGATGAATACAACGCTGTGGCCAGTGGACAGATGCCGGGTGATTCATTTCACGTAAAAACTCATTTCCACTACACGGAACCGACTGATGGGGAAATGTCTTTTCGCTGCGGCGATGTCTTCCACGTCGTTGATACTTTACATAACGGCACTGTTGGAGCGTGGCAAGTTTATCGGATAGGCCGAAATAATCAAGAAGTCCAGAAAGGGACAATACCTAATAAGGCGCGTGCTGAAGAGCTAGCTACAGCACAGTTCAATGCGACGAAGAAGGAAATGTCAGGAAATGATGGAAAGAGCAATTTCTTTAGGAGGCGACGATCTACGCATAGGCGAAGCAAGAGCCTCGGAAAGGAGCATTGGGATGAAGTGGTGCTGTCTGATAGCATTAGTAAATTCCCAGCATACGAGCGTGTAGTGTTAAAACAGCCAGGCTTCATACGGCCAGTTATAGTTTTAGGAGCCGTTTCAGATATCGCCAGAGAACGGCTGCTTACTGAAAATCCTGATAAATTCTCATCACCAAAAATGGACAGCTCCTTGGAGGACAGTAAAACAAAATCGGCAGGAATAATCCGATTATCAAGCATTAGGAATATTATGGAGAGAGGGAAACACGCCCTCTTAGACATTACTCCAAATGCGGTCGACAGATTGAACTATGCACAGTTCTATCCCATCGTTATATTTTTGAAAGCCGACAACAAACATATTATCAAACAACTGAGATCGGGATTACCAAAATCAGCCCATAAATCATCGAAGAAGCTTCTAGAACAGTGCCAACATATGGAGAGAGTATGGGGACATGTTTTTACGCACACAGTAACATTGAGCGAGGCTAACCAGAACACGTGGTTCAGCAAGCTTGTAGAATTGATACAAAGGACCCAACAGCAACAGCTATGGGTGTCGGAGACAAAGCGACCGGAGCCTCTCTCCGACGACTTTTTGTTTTCAATGTCGTCGAGTACCGAGAACAGACTCTCGTATGCTTCAAGTCCTGAAAGCGATTTGGAAGTTAGTCCTCCACCCGCTCCGAGACTAGTGAAGTCTTCCTCGGATCCCTCCATAGCGACAACTCAGGATAATTTGGATCGCGACGAAGACATGAACCATATGAACGACGCCGTGCCACCTCCTTACACGCAAAGTGGCTACGGAGACAGCAAGTACGGTTTCGCTGCCAACGGCAATGGTCAGACAAATAGTCAAAATCACAGCCAAATGAGTCACAATATGGGACCCAATGACGCACCTCCGTACCAGTGCAGTCCTATGACACATTCGCCCCCGCACTCGCCATTATATGGAACAGTTCCAGAATTGCCTCCGCGTGGCGGTCCCATAACCAGACCGGCAGGAGGAGTGCTCCTACCGGCACCGCCTCCGGGACGACCGCCGCATTCACTTCGACACAACCCACCAAACAATCGTCCAAGCGCCCAAGAGCGTCTATTCGGTCCAGCCAAAGACCCCGGAAGTGATGAAAATTCAACGTACACTGCGCGTCCGACTAGCATGATCATTCAGCCCACTCAAAGCCAAGGATCCTTGGATAGGCATAGGCATCTTGGCAACCCACAGAGTTCATACGACGGCACACCCTCATACGAATACAGTTCATCGAACAATGGTGCGGGGATCGGTTCCCGGTTGCCGCCTAACGCACCGGACGATCTCAAAGTTGCACCTCCGCCTTCCATTAAAATGGAGCCGCCACCTCCACCGAACCCGGCTGCGATGGCCACACAGAGCCCGCACAGGAACTCGAACTCGCACGAACACAACTCACTGGATTATAGGGGCCCTGAGAACAATTACAGGCCCCCAGAATACAGGAGTCCACAACAGAATCGTCCGCCGCCCATGAATGGGCACAGTCCGCACGCGCCCATGCACGCCCGTGGACCTTCACTACCGAACGTACCAACTAACGACCACGCTAAATATAGCAGCGGGCGAACGAATTCGGCATCTCAAGCAGATTACAACCAAAGAGGAGCCGCTCCCGTGCCCCCGTACAAGCCTGTGCCGCCACCGAAACCCAAACACTACCGGCCCCCGGACAGCGGCATGCACCCGAGGAACGGGAGCACGGAGCCGGTCCGGCCGCCGTCCCCGGGCGCCGGTCGCGGCTCGCACTACTCGCACCAGCACTCTCTGTCGCAGCCCTCGCACCGCCCCCACAACCACAATTACCCCCAGCAAAATATGTACGGTGGTCAGATGCCGCCACAGTCGCCGCCGTACTCCGGGCCCCCATCCCACCACCGCGGCATCAACCTGCCGCATAACCCTCACCTCATCGATTTAGCAGGAAGCCGCGAGCAACGCGGCTCAGCTTTTGAACTGTACAGAAAACCTCAACACATGCACAACTTGAGTTCATCTGACGCCTTGAATACGACCGTGGAGCATGACGAAACATTCTCGCCAAAAACTAAAAAGAAACTATCCAAAAAGCCATCGTTCATTAAAAACGCCGTCCTTGAACTGTTCCGTTCTAAAACGAAAAACTCACAGAAGGTGTCACGTCAGAAGTCGCTCTGCGAAAGCGACTTGCAGCAGAGGAACCAAGCGACACAGATCACGATGCTCAGACGCGAGAAATCGGATCTCGGCGATTTCAGTACGCACATGAGAAACACGCAAATCAGAAATCAAATGTTGCAGCGTAGCAACTCCTCATCGTGCGAGAAACCTGTCTTGAAGCCGATCCTTAAAAGACAGAGTTCGTTCTGCGACGACCGCAACGGCTCGATATGTACTATACGGGATTACGACGCGAGACCTGTCCTAAAAACGCTTAGACGACAGAATTCGATGTGCGATATCGAAACAGAACCAAAAGTTACGCCATTATTGCGCAGACAAAATTCCCTAATAGAATACAATAGACGGGGTATATATGGCCAAACTAATAATTTTAACATGATAACCAAAATAGATCCCATTTACCAAAGACGGCAACAAATAAAACACGAACCATTCTATCCCACTCAACCGCTACCTCCGGAACCAGTTTACCAAAGCAAGGACCGTCTCGTCTACGATCCTATTCCTAAACCAAGGAGGACATACACTTCTCAGTACGATGCTTCATCTGAAAATCCTTACGCAAGCAGATCAGAAGTATCAGATCAAAGCTTTGAATGTCCGTACGGAAGTCGACAAACTCTACCAATGCCATTAATCGACCCTCCTTACGCTTCCAAATCTGAGTGCTTGAGAGAGAGTGCGTACGTGACAAGAAACGAAATACAGACTGAAAGTCCCTATGCTAATAAACAAGAAATTATGTCGCAATCTGAGTTCCTATGCAAAGAGGCCCCTTATGCTAGCAAGGAACAACTGTTAAAACAAAGAATTACATCTGACTGCGCGTACGCCACTAAAGAAGAAATGCTACGGCAAAGATTTTCCGAATCTCCATACAACACAAAAGACGAACTGTTTAAACAAAGAATGGAGACTGCATATATTAAGGAACCGATATATGGTAAAAGAACTTATGAACCGCCGCCTAGCACATCGTGGTCTGAAAGTTCTTACGCCGTCCGACCTGATCGTAGATTCCACACGCCGGTCGGTTGCGCAGGAAGGATAACACCCATGGGTAAATGTATGAGCGAACCACCGTATGCGACTAGATCAGAGATGATGGCAAGAATCAGTCAAACGGATTCTCCATATAGCACGAGGTCCGAAGTGAAATCTAGTGGTTCTGACAGTCAGTACAGTAGTAGGAATGAGGTATTTGATTATAGACATGACGTCAGACCAGCTTCTGCAGAGTGCACCTATGTAACTAAACAAGAGATCATGTCACAGAAAGCAGCATTTTTAGCAAACAAAGATTCTACTTATAGCGTAAAGCTAGAAGAAAAGTTAGAAATCATAAAACAAAGAAATCAAGCTAAAAAGGACATGATTTACCAAACGAGAAAGGAGGCTAATGAAAGTGATTCTGCGAAAATAAGAGAACCATTATATGTCTCAAAAAGAGAACTGAAAGAAAGCGTCATATATGAATCGCAGCAAGAAACAAAAGAAATACAACCTGAAATACAAGATAGCAGTGCTAGAAGCAGCCCTTATGAATTAAGTGATGCTAATCATTTGTCTCGTCGGGAGCCGGTCTATCAGACAAAAGACGAAGCAGAAGCCGGACTAAAAACAGATACATTCCAAGAAATTGATTTTTCGAAACTCAGATTGACCGAGTCTAGAACAGATGCGGAAAAAGAGAAGTCACTTAATTTAGAAACGAACATACTGAAAGGCGAAGCTATGTACGCCCCTCGATTGCACGGAAAAGCTGATCACATTTCTAATGCGTTAAAAGTAACTACATCACCAACTCCATATGAATCTAGTACATCTATGGAAACGCATTATGCGTCAGAATGCAGCATGAATTTCGAAAATAAACCTCAAAGCACACCCTATACATCACAAGATATGTCTGAACAATCCCCGAAACAAAATAAGATGGTTACCTTTTGCGAAAAGATAATTGAAAAAAGTCCCGAAACTAGCCAGGAAAATTCACAAAACATGTCGAACAGTCAAAATGAAACGACAATTATAAATAACCAAAATACAGTTCTGCAGACAACGCTATCAGATAGCACTGAATTTGGCAATAAAACCCAACAAATCGAACCGGACGGTCCGCATACAACATGGGGAATATTTGACAGTGAAGGTGGCGTTTTAGAAGATAGGCAATGGGGCGTATCCCTTGTAATCCCTCCCAAGGCCATTGCTCCGGGCATCAAGCAAAAGATCTACTTTACGGTGTCAGATCCACGACTCAGTCAGCGCGTGGGGGGACCACCAATCGATATGGATAACGGTGAAGCGATGCTATCCCCACTAGTGATGTGTGGTCCGCAAGGACTAGTGTTCCTCAGACCGGTCACACTCCGCCTACCGCATTGCGCTAATGCTGTTCCATCACTAGGGCTGACAATCAAAGCGACTGACACTGAAGCTCATCTAAGCACAGACTGGGATCAGATACATCTACCTGCAACGACCACTTTGAACACGGTGGCTGTGAAAGTCGACCATTTTTGA

Protein

MFKSIKKFVFGVVAAFLLDWQTTYYTTAERSTGWETHRVRLNRVQGYGFGIAVSGGRDNPHFASGDPSIAVSDVLRGGPAEDKLQVNDRIVSVNGVSLENVEYARAVQVLRDSGAAVSLVVRRRAPAPPPTAPTTIKLALSRNGKKEDFGVVLGCKLYIKELTMRAREQLNQNGQGLCEGDVISRINNTPVTDAMTLKEARKLVESCKDRLNLVVTRELIREETVTNGNYQNNYSSLDAPSHNVYPGAEPLSPAYSSSGQNLYVAAPVRGGSGDARRGPMSHEVEQPPRPPPPRNDDYYSSRRQLYEEEAMNQRNKPPSEPRLISFQKEGSVGLRLCGGNRSGVFVSGVQPTSPAALQGLQPADKILKVNDMEMKGVTREEAVLFLLSLQDRIDLIVQHSPDEYNAVASGQMPGDSFHVKTHFHYTEPTDGEMSFRCGDVFHVVDTLHNGTVGAWQVYRIGRNNQEVQKGTIPNKARAEELATAQFNATKKEMSGNDGKSNFFRRRRSTHRRSKSLGKEHWDEVVLSDSISKFPAYERVVLKQPGFIRPVIVLGAVSDIARERLLTENPDKFSSPKMDSSLEDSKTKSAGIIRLSSIRNIMERGKHALLDITPNAVDRLNYAQFYPIVIFLKADNKHIIKQLRSGLPKSAHKSSKKLLEQCQHMERVWGHVFTHTVTLSEANQNTWFSKLVELIQRTQQQQLWVSETKRPEPLSDDFLFSMSSSTENRLSYASSPESDLEVSPPPAPRLVKSSSDPSIATTQDNLDRDEDMNHMNDAVPPPYTQSGYGDSKYGFAANGNGQTNSQNHSQMSHNMGPNDAPPYQCSPMTHSPPHSPLYGTVPELPPRGGPITRPAGGVLLPAPPPGRPPHSLRHNPPNNRPSAQERLFGPAKDPGSDENSTYTARPTSMIIQPTQSQGSLDRHRHLGNPQSSYDGTPSYEYSSSNNGAGIGSRLPPNAPDDLKVAPPPSIKMEPPPPPNPAAMATQSPHRNSNSHEHNSLDYRGPENNYRPPEYRSPQQNRPPPMNGHSPHAPMHARGPSLPNVPTNDHAKYSSGRTNSASQADYNQRGAAPVPPYKPVPPPKPKHYRPPDSGMHPRNGSTEPVRPPSPGAGRGSHYSHQHSLSQPSHRPHNHNYPQQNMYGGQMPPQSPPYSGPPSHHRGINLPHNPHLIDLAGSREQRGSAFELYRKPQHMHNLSSSDALNTTVEHDETFSPKTKKKLSKKPSFIKNAVLELFRSKTKNSQKVSRQKSLCESDLQQRNQATQITMLRREKSDLGDFSTHMRNTQIRNQMLQRSNSSSCEKPVLKPILKRQSSFCDDRNGSICTIRDYDARPVLKTLRRQNSMCDIETEPKVTPLLRRQNSLIEYNRRGIYGQTNNFNMITKIDPIYQRRQQIKHEPFYPTQPLPPEPVYQSKDRLVYDPIPKPRRTYTSQYDASSENPYASRSEVSDQSFECPYGSRQTLPMPLIDPPYASKSECLRESAYVTRNEIQTESPYANKQEIMSQSEFLCKEAPYASKEQLLKQRITSDCAYATKEEMLRQRFSESPYNTKDELFKQRMETAYIKEPIYGKRTYEPPPSTSWSESSYAVRPDRRFHTPVGCAGRITPMGKCMSEPPYATRSEMMARISQTDSPYSTRSEVKSSGSDSQYSSRNEVFDYRHDVRPASAECTYVTKQEIMSQKAAFLANKDSTYSVKLEEKLEIIKQRNQAKKDMIYQTRKEANESDSAKIREPLYVSKRELKESVIYESQQETKEIQPEIQDSSARSSPYELSDANHLSRREPVYQTKDEAEAGLKTDTFQEIDFSKLRLTESRTDAEKEKSLNLETNILKGEAMYAPRLHGKADHISNALKVTTSPTPYESSTSMETHYASECSMNFENKPQSTPYTSQDMSEQSPKQNKMVTFCEKIIEKSPETSQENSQNMSNSQNETTIINNQNTVLQTTLSDSTEFGNKTQQIEPDGPHTTWGIFDSEGGVLEDRQWGVSLVIPPKAIAPGIKQKIYFTVSDPRLSQRVGGPPIDMDNGEAMLSPLVMCGPQGLVFLRPVTLRLPHCANAVPSLGLTIKATDTEAHLSTDWDQIHLPATTTLNTVAVKVDHF

Similarity

Belongs to the MAGUK family.

Uniprot

A0A2W1BQW4 A0A3S2PER5 A0A194RM81

Pubmed

28756777 26354079

EMBL

KZ149930 PZC77418.1 RSAL01000067 RVE49317.1 KQ459995 KPJ18539.1 + More

Proteomes

UP000283053 UP000053240

Pfam

PF07653   SH3_2        + More
PF00625   Guanylate_kin
PF00791   ZU5
PF00595   PDZ

Interpro

IPR000906   ZU5_dom        + More
IPR008145   GK/Ca_channel_bsu
IPR008144   Guanylate_kin-like_dom
IPR036034   PDZ_sf
IPR011029   DEATH-like_dom_sf
IPR001452   SH3_domain
IPR036028   SH3-like_dom_sf
IPR027417   P-loop_NTPase
IPR001478   PDZ

SUPFAM

SSF52540   SSF52540        + More
SSF50156   SSF50156
SSF47986   SSF47986
SSF50044   SSF50044

ProteinModelPortal

A0A2W1BQW4 A0A3S2PER5 A0A194RM81

PDB

3TSZ E-value=4.93888e-86, Score=817

KEGG

101738587 K05701 tight junction protein 1 | (RefSeq) tight junction protein ZO-1

GO

GO:0005923 GO:0005515 GO:0016570 GO:0016593 GO:0005524 GO:0007179 GO:0006811 GO:0006032 GO:0016021 GO:0004672 GO:0048384

Length:

2094

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.33432

Exp number, first 60 AAs:

0.32766

Total prob of N-in:

0.01693

outside

1 - 2094

Pi

241.967737

Theta

177.871258

Tajima's D

1.051586

CLR

0.442911

CSRT

0.670166491675416

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics