Gene

KWMTBOMO03961  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA002349

Annotation

hydroxypyruvate_isomerase_[Bombyx_mori]

Location

Bomo_Chr7(+):7033974-7039798      View in EpiBrowser

Full name

Putative hydroxypyruvate isomerase      

Location in the cell

Cytoplasmic   Reliability : 2.825

CDS

ATGAAATTCTGTGCTAATCTGTCTTTTATGTTTGCTGAAGCTTCTTCCATTTTGGAACGATATGCTTTGGCTAAAGACGCTGGATTTAAGGCTGTAGAATCGGGTTTCCCTTTTGGTTTTAGCTTAGAACAAGTAAGAAATGCAAAACAAAGCGCCGGCTTACAACAAATCGCGATTAACTTAAAAACAGGAGACACGACCAAAGGTGAAGTTGGCGTAACTTCTGTTCCGGGTAAAGAAGACGAATTTAAAACAAATTTGAATACGACAATCGAATATGCGAAGGCCTTGGACGCGAAAAAAATTCACATAATGGCTGGTAAAGTGGAAAATCCAACTCCGAAACATTGGGAGACGTTTGAGAAAAATTTGCTATATGCTGTTGACGTCCTAAAAGGAGAGAATATCCAAGGACTAATCGAACCAATCAACCAGTATTCTATGCCCAAATATTTCTTGAGTGATTATGGAAGAGCTGTGGACATTATTAAACGTATTGACAGTCCAAATTTGAGATTGATGTTGGACATTTTTCATCTTCAGCAAATCGCTGGCGACATTACTCATAATATTACGAAACTATTGCCATACATTGGACATGTGCAAATAGCTCAGGTTCCGAATCGTAACGAACCGGACACGCCCGGAGAGATAAACTACAAGTACGTTCTAGAACACTTGGCTAAGAGCGGATACGATGAATGGGTTGGACTCGAATATAAAGCCATCGGAAACACGAAGGATGGTTTGACTTGGATCAACAATTATGGTTACAGTCTTTGA

Protein

MKFCANLSFMFAEASSILERYALAKDAGFKAVESGFPFGFSLEQVRNAKQSAGLQQIAINLKTGDTTKGEVGVTSVPGKEDEFKTNLNTTIEYAKALDAKKIHIMAGKVENPTPKHWETFEKNLLYAVDVLKGENIQGLIEPINQYSMPKYFLSDYGRAVDIIKRIDSPNLRLMLDIFHLQQIAGDITHNITKLLPYIGHVQIAQVPNRNEPDTPGEINYKYVLEHLAKSGYDEWVGLEYKAIGNTKDGLTWINNYGYSL

Description

Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).

Catalytic Activity

3-hydroxypyruvate = 2-hydroxy-3-oxopropanoate

Similarity

Belongs to the hyi family.

Feature

chain  Putative hydroxypyruvate isomerase

Uniprot

B0FPE7   Q1HPN3   A0A2W1BW00   A0A2A4JA73   S4PWU6   A0A2H1WL43   + More
A0A194QZP4   A0A212EJE8   A0A194Q7I8   D6WIB1   A0A1W5LU60   K7J2Z2   A0A154PHV7   A0A0L7QR20   A0A0M9A4V4   N6TSU0   J3JX49   A0A1W4XH11   A0A151J0J0   A0A2A3E8J8   E2A926   E9IF08   F4WMG6   A0A195CQM7   E2B5T9   A0A067R4J4   A0A158NAD0   A0A195EV60   A0A151X1P1   A0A0L7L782   A0A1L8E1U7   A0A2P8ZFY1   A0A240SY40   A0A1Y1MDC6   A0A1Y1M9E1   A0A1L8E286   A0A026WK64   A0A1B6E6M1   A0A2H8TJK5   E0VPP2   A0A2S2PRW5   A0A1B6I7L9   A0A1B6MSK2   A0A0K8TT12   J9K1C7   A0A1Q3FN95   V4A3V5   A0A2J7RMD3   A0A023EM82   A0A2R7X748   A0A2S2QTB2   A0A182H1L1   Q17J21   A0A1S4F0V8   A0A2M4AQB3   A0A2M4AQF0   U5EY56   T1J8Z1   A0A2M4BWR0   A0A2M3ZIA6   A0A182MEL4   A0A2M4BWS6   A0A2M3ZA22   A0A2M4BWY8   W5JRY8   B0WJE5   A0A1C7CZV0   A0A182SH35   A0A182XVN3   A0A0L0BPT2   A0A182IWD0   A0A182WQS4   A0A182NZ85   A0A182PZ91   A0A182XUU3   Q7QBM0   A0A182II67   A0A131XCP2   E9FR18   A0A182TED1   A0A182G067   A0A182S505   A0A182VDF0   A0A1D2NE02   A0A0A9XPZ8   A0A084VJT8   A0A0P5U891   A0A0P6FYY8   A0A0P5QDK5   A0A0N8CPL1   A0A0N7ZT43   A0A0P5S606   A0A0P5UBJ0   A0A0P5EQT8   A0A0P5EMF3   A0A0P5PM69   A0A0P5IBX6   V5HC18   A0A336MKW6   A0A182QS99  

EC Number

5.3.1.22

Pubmed

19121390    28756777    23622113    26354079    22118469    18362917    + More
19820115    20075255    23537049    22516182    20798317    21282665    21719571    24845553    21347285    26227816    29403074    28004739    24508170    30249741    20566863    26369729    23254933    24945155    26483478    17510324    20920257    23761445    20966253    25244985    26108605    12364791    14747013    17210077    28049606    21292972    27289101    25401762    26823975    24438588    25765539   

EMBL

BABH01042651    BABH01042652    EU344910    ABY57912.1    DQ443369    ABF51458.1    + More
KZ149930    PZC77377.1    NWSH01002306    PCG68568.1    GAIX01006173    JAA86387.1    ODYU01009402    SOQ53800.1    KQ460930    KPJ10754.1    AGBW02014474    OWR41623.1    KQ459579    KPI99370.1    KQ971321    EFA01436.1    KX034168    ANO53998.1    KQ434896    KZC10780.1    KQ414786    KOC60941.1    KQ435747    KOX76506.1    APGK01020350    KB740193    ENN81103.1    BT127817    KB631669    AEE62779.1    ERL85217.1    KQ980629    KYN14970.1    KZ288325    PBC28030.1    GL437711    EFN70011.1    GL762758    EFZ20816.1    GL888217    EGI64577.1    KQ977440    KYN02782.1    GL445887    EFN88908.1    KK852708    KDR18001.1    ADTU01010240    KQ981954    KYN32150.1    KQ982585    KYQ54205.1    JTDY01002463    KOB71362.1    GFDF01001393    JAV12691.1    PYGN01000070    PSN55402.1    AJWK01033290    GEZM01036957    JAV82315.1    GEZM01036958    JAV82314.1    GFDF01001392    JAV12692.1    KK107167    QOIP01000010    EZA56442.1    RLU17501.1    GEDC01019636    GEDC01003761    JAS17662.1    JAS33537.1    GFXV01002500    MBW14305.1    DS235366    EEB15348.1    GGMR01019593    MBY32212.1    GECU01032502    GECU01024797    GECU01019776    GECU01008714    JAS75204.1    JAS82909.1    JAS87930.1    JAS98992.1    GEBQ01001056    JAT38921.1    GDAI01000106    JAI17497.1    ABLF02038908    GFDL01005980    JAV29065.1    KB202567    ESO89670.1    NEVH01002562    PNF41988.1    GAPW01003180    JAC10418.1    KK857027    PTY26715.1    GGMS01011784    MBY80987.1    JXUM01103672    KQ564823    KXJ71701.1    CH477235    EAT46690.1    GGFK01009650    MBW42971.1    GGFK01009621    MBW42942.1    GANO01000584    JAB59287.1    JH431968    GGFJ01008384    MBW57525.1    GGFM01007502    MBW28253.1    AXCM01005162    GGFJ01008385    MBW57526.1    GGFM01004537    MBW25288.1    GGFJ01008383    MBW57524.1    ADMH02000272    ETN67172.1    DS231959    EDS29119.1    JRES01001565    KNC22016.1    AAAB01008879    EAA08468.5    APCN01002105    GEFH01004711    JAP63870.1    GL732523    EFX90267.1    LJIJ01000071    ODN03490.1    GBHO01021913    GDHC01014855    JAG21691.1    JAQ03774.1    ATLV01013869    KE524905    KFB38232.1    GDIP01116658    JAL87056.1    GDIQ01042287    JAN52450.1    GDIQ01136949    JAL14777.1    GDIP01111359    JAL92355.1    GDIP01215193    JAJ08209.1    GDIQ01098309    JAL53417.1    GDIP01119005    GDIP01119004    JAL84710.1    GDIQ01266442    GDIQ01139403    GDIQ01098310    JAJ85282.1    GDIQ01270586    GDIQ01267725    JAJ83999.1    GDIQ01136950    JAL14776.1    GDIQ01214620    JAK37105.1    GANP01009574    JAB74894.1    UFQS01001354    UFQT01001354    SSX10485.1    SSX30171.1    AXCN02000300   

Proteomes

UP000005204    UP000218220    UP000053240    UP000007151    UP000053268    UP000007266    + More
UP000002358    UP000076502    UP000053825    UP000053105    UP000019118    UP000030742    UP000192223    UP000078492    UP000242457    UP000000311    UP000007755    UP000078542    UP000008237    UP000027135    UP000005205    UP000078541    UP000075809    UP000037510    UP000245037    UP000092461    UP000053097    UP000279307    UP000009046    UP000007819    UP000030746    UP000235965    UP000069940    UP000249989    UP000008820    UP000075883    UP000000673    UP000002320    UP000075882    UP000075901    UP000076408    UP000037069    UP000075880    UP000075920    UP000075884    UP000075885    UP000076407    UP000007062    UP000075840    UP000000305    UP000075902    UP000069272    UP000075900    UP000075903    UP000094527    UP000030765    UP000075886   

PRIDE

B0FPE7    Q1HPN3   

Pfam

PF01261   AP_endonuc_2

Interpro

IPR026040   HyI-like        + More
IPR013022   Xyl_isomerase-like_TIM-brl       
IPR036237   Xyl_isomerase-like_sf       
IPR006189   CHASE_dom       

SUPFAM

SSF51658   SSF51658       

ProteinModelPortal

B0FPE7   Q1HPN3   A0A2W1BW00   A0A2A4JA73   S4PWU6   A0A2H1WL43   + More
A0A194QZP4   A0A212EJE8   A0A194Q7I8   D6WIB1   A0A1W5LU60   K7J2Z2   A0A154PHV7   A0A0L7QR20   A0A0M9A4V4   N6TSU0   J3JX49   A0A1W4XH11   A0A151J0J0   A0A2A3E8J8   E2A926   E9IF08   F4WMG6   A0A195CQM7   E2B5T9   A0A067R4J4   A0A158NAD0   A0A195EV60   A0A151X1P1   A0A0L7L782   A0A1L8E1U7   A0A2P8ZFY1   A0A240SY40   A0A1Y1MDC6   A0A1Y1M9E1   A0A1L8E286   A0A026WK64   A0A1B6E6M1   A0A2H8TJK5   E0VPP2   A0A2S2PRW5   A0A1B6I7L9   A0A1B6MSK2   A0A0K8TT12   J9K1C7   A0A1Q3FN95   V4A3V5   A0A2J7RMD3   A0A023EM82   A0A2R7X748   A0A2S2QTB2   A0A182H1L1   Q17J21   A0A1S4F0V8   A0A2M4AQB3   A0A2M4AQF0   U5EY56   T1J8Z1   A0A2M4BWR0   A0A2M3ZIA6   A0A182MEL4   A0A2M4BWS6   A0A2M3ZA22   A0A2M4BWY8   W5JRY8   B0WJE5   A0A1C7CZV0   A0A182SH35   A0A182XVN3   A0A0L0BPT2   A0A182IWD0   A0A182WQS4   A0A182NZ85   A0A182PZ91   A0A182XUU3   Q7QBM0   A0A182II67   A0A131XCP2   E9FR18   A0A182TED1   A0A182G067   A0A182S505   A0A182VDF0   A0A1D2NE02   A0A0A9XPZ8   A0A084VJT8   A0A0P5U891   A0A0P6FYY8   A0A0P5QDK5   A0A0N8CPL1   A0A0N7ZT43   A0A0P5S606   A0A0P5UBJ0   A0A0P5EQT8   A0A0P5EMF3   A0A0P5PM69   A0A0P5IBX6   V5HC18   A0A336MKW6   A0A182QS99  

PDB

3NGF     E-value=8.11842e-52,     Score=513

KEGG

733011    K01816 hydroxypyruvate isomerase [EC:5.3.1.22] | (RefSeq) Hyi; hydroxypyruvate isomerase

PATHWAY

00630    Glyoxylate and dicarboxylate metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0008903   GO:0016857   GO:0016853  

Length:

260

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00506999999999999

Exp number, first 60 AAs:

0.00429999999999999

Total prob of N-in:

0.02354

outside

1  -  260

 

 

Pi

238.472375

Theta

179.896629

Tajima's D

1.379971

CLR

5.686351

CSRT

0.75991200439978

Interpretation

Uncertain