Gene

KWMTBOMO03892  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA010209

Annotation

cell_differentiation_protein_RCD1_homolog_[Bombyx_mori]

Location

Bomo_Chr7(+):5961675-5962719      View in EpiBrowser

Full name

CCR4-NOT transcription complex subunit 9      

Alternative Name

Cell differentiation protein RQCD1 homolog

Location in the cell

PlasmaMembrane   Reliability : 2.732

CDS

ATGAGTCGTTTAACGCCAATCGTACAAAATATGATTAATATGAGCGCACAGCAGAGTCCGGCAAATATGCAGGCTGCCGTGGACAGGGAAAAGATATATTCCTGGATTCTAGAGCTATGCAATCCCGACACTCGTGAAAATGCGCTATTAGAACTGAGTAAAAAACGAGAAGTGGTTCCTGACTTGGCGCCAATGCTGTGGCATAGCTTCGGTACAATCGCTGCTCTCCTACAGGAAATAACCAACATATACGTGGCAATGATTCCTCCGACTTTGACTGCTCATCAGAGCAACCGTGTCTGTAATGCTTTGGCTTTGATGCAATGTGTTGCATCTCATCCAGAAACAAGATCTGCGTTTCTTCAAGCCCATGTTCCCTTGTTCCTTTACCCATTCCTCCACACTGTTTCTAAAACTAGACCTTTTGAATACCTACGTCTTACCAGTCTTGGAGTAATAGGTGCATTAGTGAAAACGGATGAGCAAGAAGTTATAACATTTCTATTGACTACCGAAATTATACCACTGTGTCTGCGCATTATGGAAAATGGATCTGAACTCTCTAAAACTGTAGCTACGTTTATCCTACAGAAAATTTTGCTTGACGACAGTGGACTTTGTTATATTTGCCAAACCTATGACAGATTTTCTCATGTTGCCATGATTTTGGGGAAAATGGTACTTTCACTAGCTAAAGATCCATCAGCTCGGTTGTTAAAGCATGTAGTAAGATGTTACCTTCGTTTATCTGACAACCCAAGAGCAAGAGAAGCTTTAAGACAATGCTTGCCAGACCAACTCCGTGATGCAACTTTTACAGCATGCCTTCAAGAAGACAATTCTACAAAGCATTGGTTGGCTCAACTCATTAAGAACTTGGAAGCACAGCCTCCTCCGGCCAGTCCAGCTCAGCAGAACATGTGA

Protein

MSRLTPIVQNMINMSAQQSPANMQAAVDREKIYSWILELCNPDTRENALLELSKKREVVPDLAPMLWHSFGTIAALLQEITNIYVAMIPPTLTAHQSNRVCNALALMQCVASHPETRSAFLQAHVPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVITFLLTTEIIPLCLRIMENGSELSKTVATFILQKILLDDSGLCYICQTYDRFSHVAMILGKMVLSLAKDPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLRDATFTACLQEDNSTKHWLAQLIKNLEAQPPPASPAQQNM

Description

Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down-regulation of MYB- and JUN-dependent transcription. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors. May play a role in cell differentiation.

Subunit

Homodimer. Component of the CCR4-NOT complex.
Homodimer. Component of the CCR4-NOT complex (By similarity).

Similarity

Belongs to the CNOT9 family.

Keywords

Activator   Complete proteome   Cytoplasm   Nucleus   Reference proteome   Repressor   RNA-mediated gene silencing   Transcription   Transcription regulation   Translation regulation  

Feature

chain  CCR4-NOT transcription complex subunit 9

Uniprot

A0A212ERZ8   S4PBB0   A0A0L7LK19   A0A2A4JZC0   I4DNJ6   A0A194RPI8   + More
A0A194Q5R5   H9JL08   D4NXP4   A0A2H1WMZ9   A0A222AIZ0   A0A3S2NHH9   A0A2J7PDY7   A0A1B6EI93   A0A1B6EIN7   A0A1B6LJZ7   E0VHW2   A0A2A3E496   A0A088AH98   A0A1B6CYZ2   A0A1B6E3Y4   A0A0J7K982   A0A195DCY9   A0A0N0BBH7   A0A195FW70   E2BD53   A0A158NS60   E2AWG5   A0A151WH26   F4WJQ1   A0A1W4W5G8   A0A232F2M2   E9IR20   A0A0P4VMN4   R4FLK5   A0A2R7VTL1   A0A0V0G8H5   A0A026X1J9   A0A023F9H4   A0A161TH70   A0A224XGR6   A0A069DR60   D6WJX4   A0A1Y1NL77   J3JWL2   A0A023EQ69   Q174K1   A0A195BC81   A0A0A9YV04   A0A1B6IXH7   A0A146LPW8   B0WBV0   A0A1Q3F885   A0A0K8TMC6   A0A1S3HMC2   A0A1S3CXA5   A0A1S3CYL7   A0A336MA08   A0A1Q3F8B8   A0A1Q3F867   A0A1L8EVQ1   Q6P819   Q6IP65   A0A091FJB6   A0A091PCG2   E9HFR5   A0A2I0UKJ1   H3BDT3   A0A091NMQ8   A0A2Y9R5U6   A0A164L5M9   A0A3Q0CQS0   A0A093E6U2   A0A093JBC6   A0A093FE01   A0A093Q7M1   A0A091U6L4   A0A091I7G3   A0A091UUS7   A0A091M981   A0A087V2K0   A0A091JNW0   A0A099ZZ37   A0A091UMR0   A0A093P5Z6   A0A091SVA7   A0A093J034   A0A091EAI7   A0A091RP85   A0A091T2F1   A0A091P204   A0A087QTT3   A0A094L647   A0A091QAC3   R0LIK7   A0A091N894   H0Z510   A0A2K5HP21   U6DA15   K9IID3  

Pubmed

22118469    23622113    26227816    22651552    26354079    19121390    + More
20566863    20798317    21347285    21719571    28648823    21282665    27129103    24508170    30249741    25474469    26334808    18362917    19820115    28004739    22516182    24945155    17510324    25401762    26823975    26369729    27762356    21292972    9215903    20360741   

EMBL

AGBW02012891    OWR44270.1    GAIX01006002    JAA86558.1    JTDY01000889    KOB75546.1    + More
NWSH01000329    PCG77365.1    AK402971    BAM19486.1    KQ460075    KPJ17936.1    KQ459582    KPI98740.1    BABH01011457    GU454861    ADD54617.1    ODYU01009759    SOQ54408.1    KY563841    ASO76347.1    RSAL01003985    RVE40203.1    NEVH01026122    PNF14545.1    GECZ01032112    JAS37657.1    GECZ01031980    JAS37789.1    GEBQ01015977    JAT24000.1    DS235172    EEB12968.1    KZ288427    PBC25901.1    GEDC01018835    JAS18463.1    GEDC01004652    JAS32646.1    LBMM01011538    KMQ86776.1    KQ980989    KYN10746.1    KQ438551    KOX67191.1    KQ981208    KYN44688.1    GL447569    EFN86361.1    ADTU01024525    ADTU01024526    GL443286    EFN62265.1    KQ983136    KYQ47117.1    GL888186    EGI65543.1    NNAY01001156    OXU24945.1    GL765043    EFZ16974.1    GDKW01002478    JAI54117.1    GAHY01002074    JAA75436.1    KK854081    PTY10864.1    GECL01001877    JAP04247.1    KK107031    QOIP01000008    EZA62127.1    RLU19286.1    RLU19625.1    GBBI01000561    JAC18151.1    GEMB01000704    JAS02432.1    GFTR01004740    JAW11686.1    GBGD01002331    JAC86558.1    KQ971342    EFA03649.1    GEZM01003813    GEZM01003812    JAV96547.1    BT127630    AEE62592.1    GAPW01002904    JAC10694.1    CH477409    EAT41504.1    KQ976528    KYM81827.1    GBHO01006747    GBRD01003236    JAG36857.1    JAG62585.1    GECU01016059    JAS91647.1    GDHC01009300    JAQ09329.1    DS231882    EDS42880.1    GFDL01011322    JAV23723.1    GDAI01002300    JAI15303.1    UFQS01000552    UFQT01000552    SSX04844.1    SSX25207.1    GFDL01011307    JAV23738.1    GFDL01011275    JAV23770.1    CM004483    CM004482    OCT61020.1    OCT63424.1    CR760361    BC061412    BC072053    KL447081    KFO69703.1    KK670975    KFQ04943.1    GL732637    EFX69422.1    KZ505705    PKU46560.1    AFYH01036142    AFYH01036143    KK837592    KFP80780.1    LRGB01003193    KZS03816.1    KL457336    KFV10166.1    KK611209    KFW12335.1    KK631483    KFV55937.1    KL670757    KFW80157.1    KK419073    KFQ86096.1    KL218243    KFP03320.1    KL410197    KFQ94719.1    KK525734    KFP68056.1    KL477547    KFO06842.1    KK502214    KFP21623.1    KL869907    KGL86403.1    KK458191    KFQ77619.1    KL225119    KFW67652.1    KK935416    KFQ46922.1    KK567526    KFW05247.1    KK718211    KFO55053.1    KK822712    KFQ40759.1    KK496958    KFQ66114.1    KK649309    KFQ00853.1    KL225902    KFM04637.1    KL277532    KFZ66823.1    KK692832    KFQ22562.1    KB743225    EOB00198.1    KL379101    KFP86038.1    ABQF01010787    HAAF01007632    CCP79456.1    GABZ01007202    JAA46323.1   

Proteomes

UP000007151    UP000037510    UP000218220    UP000053240    UP000053268    UP000005204    + More
UP000283053    UP000235965    UP000009046    UP000242457    UP000005203    UP000036403    UP000078492    UP000053105    UP000078541    UP000008237    UP000005205    UP000000311    UP000075809    UP000007755    UP000192223    UP000215335    UP000053097    UP000279307    UP000007266    UP000008820    UP000078540    UP000002320    UP000085678    UP000079169    UP000186698    UP000008143    UP000053760    UP000000305    UP000008672    UP000248480    UP000076858    UP000189706    UP000053258    UP000054308    UP000053283    UP000053119    UP000053858    UP000054081    UP000052976    UP000053286    UP000007754    UP000233080   

PRIDE

H9JL08    D4NXP4    Q6IP65   

Interpro

IPR016024   ARM-type_fold        + More
IPR011989   ARM-like       
IPR007216   CNOT9       

SUPFAM

SSF48371   SSF48371       

Gene 3D

1.25.10.10    

ProteinModelPortal

A0A212ERZ8   S4PBB0   A0A0L7LK19   A0A2A4JZC0   I4DNJ6   A0A194RPI8   + More
A0A194Q5R5   H9JL08   D4NXP4   A0A2H1WMZ9   A0A222AIZ0   A0A3S2NHH9   A0A2J7PDY7   A0A1B6EI93   A0A1B6EIN7   A0A1B6LJZ7   E0VHW2   A0A2A3E496   A0A088AH98   A0A1B6CYZ2   A0A1B6E3Y4   A0A0J7K982   A0A195DCY9   A0A0N0BBH7   A0A195FW70   E2BD53   A0A158NS60   E2AWG5   A0A151WH26   F4WJQ1   A0A1W4W5G8   A0A232F2M2   E9IR20   A0A0P4VMN4   R4FLK5   A0A2R7VTL1   A0A0V0G8H5   A0A026X1J9   A0A023F9H4   A0A161TH70   A0A224XGR6   A0A069DR60   D6WJX4   A0A1Y1NL77   J3JWL2   A0A023EQ69   Q174K1   A0A195BC81   A0A0A9YV04   A0A1B6IXH7   A0A146LPW8   B0WBV0   A0A1Q3F885   A0A0K8TMC6   A0A1S3HMC2   A0A1S3CXA5   A0A1S3CYL7   A0A336MA08   A0A1Q3F8B8   A0A1Q3F867   A0A1L8EVQ1   Q6P819   Q6IP65   A0A091FJB6   A0A091PCG2   E9HFR5   A0A2I0UKJ1   H3BDT3   A0A091NMQ8   A0A2Y9R5U6   A0A164L5M9   A0A3Q0CQS0   A0A093E6U2   A0A093JBC6   A0A093FE01   A0A093Q7M1   A0A091U6L4   A0A091I7G3   A0A091UUS7   A0A091M981   A0A087V2K0   A0A091JNW0   A0A099ZZ37   A0A091UMR0   A0A093P5Z6   A0A091SVA7   A0A093J034   A0A091EAI7   A0A091RP85   A0A091T2F1   A0A091P204   A0A087QTT3   A0A094L647   A0A091QAC3   R0LIK7   A0A091N894   H0Z510   A0A2K5HP21   U6DA15   K9IID3  

PDB

4CT6     E-value=8.00519e-131,     Score=1195

KEGG

100384888    K12606 CCR4-NOT transcription complex subunit 9 | (RefSeq) rcd1; cell differentiation protein RCD1 h

PATHWAY

03018    RNA degradation - Bombyx mori (domestic silkworm)

GO

GO:0006402   GO:0030014   GO:0000932   GO:0017148   GO:0030015   GO:0005634   GO:2000327   GO:0033147   GO:0031047   GO:0006417   GO:0033138   GO:0045742   GO:0019904   GO:0042803   GO:0019221   GO:0005154   GO:0019900   GO:0005488   GO:0008270   GO:0031515   GO:0006412   GO:0007219   GO:0007275   GO:0016021   GO:0004672   GO:0048384  

PANTHER

PTHR12262:SF0  

Subcellular location

Nucleus  
Cytoplasm  
P-body  

Length:

307

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.458919999999999

Exp number, first 60 AAs:

0.00128

Total prob of N-in:

0.04570

outside

1  -  307

 

 

Pi

138.205203

Theta

129.440259

Tajima's D

0.308598

CLR

4.617438

CSRT

0.458977051147443

Interpretation

Uncertain