Gene

KWMTBOMO03834

Pre Gene Modal

BGIBMGA010090

Annotation

PREDICTED:_fibroblast_growth_factor_receptor_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr7(+):3514790-3621947      View in EpiBrowser

Full name

Fibroblast growth factor receptor      

Location in the cell

Cytoplasmic   Reliability : 2.258 Nuclear   Reliability : 1.744

CDS

ATGGTGGAGTGGTTTAAAGATGGCCAGGCTCTGGATGGAGTCTCCAAGAGGATAACACAACAAAGGCAATGGTTAAGAATAAAAGGATTTAGAGCGAAAGACGCTGGTGTTTACTCGTGCCAAAACGAAGAAGATAAGTTCAAGGAAATGGCTGTCACGATCAAGCACAAGATTGGACAAGATCAAGATAATTTAGAAGAATATCAAGCAGATGTGGATATAGACAGGCCAATGCCAGAAATACTATCGCAACACCAAGCTGTTTCGCTACACGAAAATAACAAATTTGAAGAAAATACGACTGAAATAAAACGATTAGCAAGAACAATGAAATTAAAAGAAATCGATCCAAAAGATGAGGATCCTGATGATAAAAGTGAAAAGGATCATCCCGTTTACGGACACGTGGATGAAACTAAAAAGAAATACCCTCCCAAATTCAAACATCCATCAAAAATGTACACTATGGAAATGAAGCCTGCTGGCAGCTCTGTCAGATTTAAATGTCCTGCTGAAGGGAATCCCACGCCAAATATTACGTGGTACAAAAACAAAAGTAATCCAATACAAAGGACATACTTCCAGCCTAGCTACGCTAAATGGGCGATAAATTTAGATGAACTTACCAAAGCAGATAACGGAAATTACACTTGCGTTGTTTGCAATGAACTGGGTTGCATTGAGCACACTGTTGTGTTACACATACAAGAGCGCCTATACGCGAAGCCAGTTCTCACGCAAGGCGCAGTCAATCAAACTCGGATCGTAGGAGAGACGGCAAGATTCTCTTGCGATTTCCTCTCGGACATGCATCCGTATCTCTACTGGATGTATTTCTCGAAGGATGATTACGTCTATAGCGATGCCATCGATAGCGACGGCTCTGTTCTAGACTTAAATGACACGAGCAAATTCGTAACGAGCGATGATCCGTTTGACAAGTTGGAGCAGTTGACTTTGTACAACGTGACAAAAGAAGACGAAGGCTGGTACGTCTGCGTCGCTCTAAACACACTCGGCAATACAACCGCGAAAGGATACCTTACTGTTCTTGAATCTCCTCCGGAATTAGAGATACCGGATCACGGCAAGCACACGCTTCTAATCAACATACTGACCGCGGTACTGGGGGCTATGTTCTTCGTGGCCGCCATTATAGTGGTGATGGTCTTCAAGAAGCTAAAGCGAGAGAAGTTGAAGAAACAACTGGCAATAGAGACCGCGAGAGCTGTTATCGTTACGCACTGGACGAAGAAGGTTACAGTCGAGAAGCCACAGATGAACGGGTCTCCTAATACTACTGGAGAAGCTCTGCTGATGCCAGTCGTCAAAATCGAGAAGCAGAAACTGTCACAAGTACAGAATAATACATCGGACTCGATGATGATGTCGGAATACGAACTCCCAATGGACATAGACTGGGAAGTTCCCAGGGAATCGTTGTCGTTGGGAAAAGTCCTCGGCGAAGGGGAGTTCGGGAAGGTGGTGAAGGCTGAGTGCATCGGCATCCTGAAGCCGGGCTTGCAGTCCGTTGTTGCGGTCAAGATGTTGAAAGAGGGTCACACGGATGCTGAAATGATGGCTTTGGTGTCGGAAATGGAGATGATGAAGATGATAGGGAAACACGTAAACATAATCAACTTGTTGGGATGCTGCACGCAGGACGGACCTCTTTATGTCATAGTCGAGTACGCACCAAATGGAAACCTGAGGGAATTCCTGAGGAATCACAGACCCGGGAATAGGTACGAGTCACCAAACGAAGATTTGAAAGAAAAGAAGACGCTGACACAAAAAGATCTTGTATCTTTCTCCTATCAAGTGGCCAGAGGAATGGAGTATTTGGCTTCGAGACGATGCATCCATCGCGACTTGGCTGCTCGTAACGTGCTCGTGTCGGACGACTGCGTCCTCAAGATCGCCGACTTTGGTCTCGCTAAAGACGTCCACAGCAACGACTACTACAGGAAGAAGACAGAAGGGAGACTTCCCGTCCGGTGGATGGCGCCGGAGTCCTTGTACCACAAAGTGTTCACAACGCAGACCGACGTTTGGTCGTTTGGCGTGTTGCTATGGGAGATAATGACGCTGGGAGGCACCCCCTACCCCACCGTCCCCGGCCAGTACATGTACCAGCACCTCAGCGCCGGACACCGCATGGAGAAGCCGCCGTGCTGCAGTCTCGAGATTTACATGTTAATGCGCGAATGCTGGTCGTTTTCACCCGGCGACCGGCCGTCCTTCACCGAGCTGGTGGAGGATCTGGACAAGATTCTTACGGTCACAGCCAACCAGGAGTACCTGGACCTAGGCCTGCCACAGTTAGACACACCTCCTTCAAGTTACGACGGCTCCGGTGACGAAAGCGACGCTGAATTTCCATTTATAAAATAA

Protein

MVEWFKDGQALDGVSKRITQQRQWLRIKGFRAKDAGVYSCQNEEDKFKEMAVTIKHKIGQDQDNLEEYQADVDIDRPMPEILSQHQAVSLHENNKFEENTTEIKRLARTMKLKEIDPKDEDPDDKSEKDHPVYGHVDETKKKYPPKFKHPSKMYTMEMKPAGSSVRFKCPAEGNPTPNITWYKNKSNPIQRTYFQPSYAKWAINLDELTKADNGNYTCVVCNELGCIEHTVVLHIQERLYAKPVLTQGAVNQTRIVGETARFSCDFLSDMHPYLYWMYFSKDDYVYSDAIDSDGSVLDLNDTSKFVTSDDPFDKLEQLTLYNVTKEDEGWYVCVALNTLGNTTAKGYLTVLESPPELEIPDHGKHTLLINILTAVLGAMFFVAAIIVVMVFKKLKREKLKKQLAIETARAVIVTHWTKKVTVEKPQMNGSPNTTGEALLMPVVKIEKQKLSQVQNNTSDSMMMSEYELPMDIDWEVPRESLSLGKVLGEGEFGKVVKAECIGILKPGLQSVVAVKMLKEGHTDAEMMALVSEMEMMKMIGKHVNIINLLGCCTQDGPLYVIVEYAPNGNLREFLRNHRPGNRYESPNEDLKEKKTLTQKDLVSFSYQVARGMEYLASRRCIHRDLAARNVLVSDDCVLKIADFGLAKDVHSNDYYRKKTEGRLPVRWMAPESLYHKVFTTQTDVWSFGVLLWEIMTLGGTPYPTVPGQYMYQHLSAGHRMEKPPCCSLEIYMLMRECWSFSPGDRPSFTELVEDLDKILTVTANQEYLDLGLPQLDTPPSSYDGSGDESDAEFPFIK

Catalytic Activity

ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein]

Similarity

Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
Belongs to the protein kinase superfamily. Tyr protein kinase family.

Feature

chain  Fibroblast growth factor receptor

Uniprot

Q1JUB8   A0A2A4J3S4   Q1JUB7   A0A1U9WTL1   A0A2A4J273   A0A2H1WDQ4   + More
H9JKN9   A0A194QZK6   A0A194QDK7   A0A3S2LYN7   A0A212ESE0   A0A3L8E314   A0A0L7QMK7   A0A1W4XDH0   D6W6I2   A0A158NVU7   A0A0J7NYR0   A0A1W4X2U0   A0A195C7D7   A0A195BB67   A0A1B6K6L4   A0A1Y1KI53   F4WMU2   A0A0M9A011   A0A1Y1KD17   A0A026WLD5   A0A1B6C942   A0A224XJ43   A0A023F2X0   A0A0C9PZY2   A0A0C9QAF7   A0A2H8TF21   J9JQ68   A0A146M4S1   A0A1B6CPE6   A0A2S2PR88   A0A2S2Q3V2   A0A0U3IZJ2   E0VYK9   T1HVZ3   A0A154PKK4   A0A1J1J6U3   A0A182QYK6   A0A1J1J525   B0WJF5   A0A151J504   A0A1I8JVZ3   A0A182LC51   A0A088A4F4   A0A1S4GGZ1   Q5TTJ6   A0A182U4Y9   A0A2C9GQG7   A0A182UVU8   E9INR0   A0A195EWL7   A0A232EMX8   A0A151WPX0   A0A182LZD6   W5JVS5   A0A1I8JW45   A0A3F2YSE5   A0A1S4GGY3   F5HKZ1   Q17J18   E2A9R7   A0A182H093   A0A084VKS5   A0A067RG01   E9FS22   A0A0P6DKL4   A0A0P6ENA3   A0A0P5HSF2   A0A0P5VR39   A0A0P6AQB5   Q17BM1   A0A0P5DHL5   A0A0P5WVM3   A0A164YGT7   A0A0P6DJA9   A0A0P5U328   A0A1L8DJF7   A0A1L8DJG4   A0A0L0CAR6   A0A0K8VZG5   A0A034VJE0   A0A0A1WV42   A0A0P5CL91   A0A1I8M3C9   A0A1I8NXE3   A0A0P5TI12   A0A1I8M2A8   A0A0N8CJ71   A0A1L8DJR7   A0A131Z5C6   B4LZ96   A0A224YMV3   A0A147BNF1  

EC Number

2.7.10.1

Pubmed

16699027    19121390    26354079    22118469    30249741    18362917    + More
19820115    21347285    28004739    21719571    24508170    25474469    26823975    20566863    20966253    12364791    21282665    28648823    20920257    23761445    17510324    20798317    26483478    24438588    24845553    21292972    26108605    25348373    25830018    25315136    26830274    17994087    18057021    28797301    29652888   

EMBL

AB247566    BAE94421.1    NWSH01003526    PCG66164.1    AB247567    BAE94422.1    + More
KX979914    AQY56784.1    PCG66165.1    ODYU01007976    SOQ51198.1    BABH01024924    KQ460930    KPJ10719.1    KQ459167    KPJ03504.1    RSAL01000112    RVE47023.1    AGBW02012819    OWR44397.1    QOIP01000001    RLU27094.1    KQ414885    KOC59858.1    KQ971307    EFA11574.2    ADTU01027496    LBMM01000766    KMQ97540.1    KQ978231    KYM96081.1    KQ976529    KYM81796.1    GECU01035110    GECU01000609    JAS72596.1    JAT07098.1    GEZM01086524    GEZM01086520    JAV59275.1    GL888221    EGI64476.1    KQ435803    KOX73103.1    GEZM01086523    GEZM01086521    JAV59274.1    KK107159    EZA56758.1    GEDC01027449    JAS09849.1    GFTR01008377    JAW08049.1    GBBI01003323    JAC15389.1    GBYB01007123    JAG76890.1    GBYB01011428    JAG81195.1    GFXV01000874    MBW12679.1    ABLF02028955    GDHC01004210    JAQ14419.1    GEDC01021946    JAS15352.1    GGMR01019235    MBY31854.1    GGMS01003088    MBY72291.1    KT355591    ALV82510.1    DS235845    EEB18465.1    ACPB03001692    ACPB03001693    ACPB03001694    ACPB03001695    ACPB03001696    KQ434948    KZC12382.1    CVRI01000072    CRL07508.1    AXCN02000226    CRL07509.1    DS231959    EDS29129.1    KQ980079    KYN17818.1    AAAB01008879    EAL40705.4    APCN01002106    GL764397    EFZ17715.1    KQ981940    KYN32670.1    NNAY01003260    OXU19719.1    KQ982850    KYQ49949.1    AXCM01000265    ADMH02000272    ETN67170.1    EGK96952.1    CH477235    EAT46693.1    GL437918    EFN69869.1    JXUM01100898    JXUM01100899    KQ564607    KXJ72033.1    ATLV01014246    KE524949    KFB38569.1    KK852498    KDR22672.1    GL732523    EFX89956.1    GDIQ01076139    JAN18598.1    GDIQ01061499    JAN33238.1    GDIQ01223583    JAK28142.1    GDIP01096690    JAM07025.1    GDIP01026044    JAM77671.1    CH477320    EAT43645.1    GDIP01172631    JAJ50771.1    GDIP01080986    JAM22729.1    LRGB01000915    KZS15239.1    GDIQ01076138    JAN18599.1    GDIP01120683    JAL83031.1    GFDF01007475    JAV06609.1    GFDF01007476    JAV06608.1    JRES01000760    KNC28549.1    GDHF01033965    GDHF01033128    GDHF01024275    GDHF01017768    GDHF01008011    GDHF01000710    GDHF01000440    JAI18349.1    JAI19186.1    JAI28039.1    JAI34546.1    JAI44303.1    JAI51604.1    JAI51874.1    GAKP01016339    GAKP01016338    JAC42614.1    GBXI01011917    JAD02375.1    GDIP01172630    JAJ50772.1    GDIP01126478    JAL77236.1    GDIP01126479    JAL77235.1    GFDF01007469    JAV06615.1    GEDV01003236    JAP85321.1    CH940650    EDW67103.2    KRF83103.1    GFPF01007801    MAA18947.1    GEGO01003432    JAR91972.1   

Proteomes

UP000218220    UP000005204    UP000053240    UP000053268    UP000283053    UP000007151    + More
UP000279307    UP000053825    UP000192223    UP000007266    UP000005205    UP000036403    UP000078542    UP000078540    UP000007755    UP000053105    UP000053097    UP000007819    UP000009046    UP000015103    UP000076502    UP000183832    UP000075886    UP000002320    UP000078492    UP000076407    UP000075882    UP000005203    UP000007062    UP000075902    UP000075840    UP000075903    UP000078541    UP000215335    UP000075809    UP000075883    UP000000673    UP000008820    UP000000311    UP000069940    UP000249989    UP000030765    UP000027135    UP000000305    UP000076858    UP000037069    UP000095301    UP000095300    UP000008792   

PRIDE

Q1JUB8    H9JKN9   

Pfam

PF07679   I-set        + More
PF07714   Pkinase_Tyr
PF00047   ig
PF13895   Ig_2
PF12906   RINGv
PF17862   AAA_lid_3
PF03722   Hemocyanin_N
PF09262   PEX-1N
PF03723   Hemocyanin_C
PF00004   AAA

Interpro

IPR011009   Kinase-like_dom_sf        + More
IPR013098   Ig_I-set       
IPR001245   Ser-Thr/Tyr_kinase_cat_dom       
IPR003599   Ig_sub       
IPR007110   Ig-like_dom       
IPR017441   Protein_kinase_ATP_BS       
IPR013783   Ig-like_fold       
IPR003598   Ig_sub2       
IPR016248   FGF_rcpt_fam       
IPR036179   Ig-like_dom_sf       
IPR000719   Prot_kinase_dom       
IPR008266   Tyr_kinase_AS       
IPR020635   Tyr_kinase_cat_dom       
IPR013151   Immunoglobulin       
IPR013083   Znf_RING/FYVE/PHD       
IPR011016   Znf_RING-CH       
IPR001005   SANT/Myb       
IPR009057   Homeobox-like_sf       
IPR017884   SANT_dom       
IPR037020   Hemocyanin_C_sf       
IPR003959   ATPase_AAA_core       
IPR015342   PEX-N_psi_beta-barrel       
IPR027417   P-loop_NTPase       
IPR003960   ATPase_AAA_CS       
IPR005204   Hemocyanin_N       
IPR014756   Ig_E-set       
IPR041569   AAA_lid_3       
IPR003593   AAA+_ATPase       
IPR009010   Asp_de-COase-like_dom_sf       
IPR036697   Hemocyanin_N_sf       
IPR029067   CDC48_domain_2-like_sf       
IPR005203   Hemocyanin_C       
IPR013106   Ig_V-set       

SUPFAM

SSF56112   SSF56112        + More
SSF48726   SSF48726       
SSF46689   SSF46689       
SSF52540   SSF52540       
SSF50692   SSF50692       
SSF48050   SSF48050       
SSF54585   SSF54585       
SSF81296   SSF81296       

Gene 3D

2.60.40.10     3.30.40.10     1.20.1370.10     2.60.40.1520    

ProteinModelPortal

Q1JUB8   A0A2A4J3S4   Q1JUB7   A0A1U9WTL1   A0A2A4J273   A0A2H1WDQ4   + More
H9JKN9   A0A194QZK6   A0A194QDK7   A0A3S2LYN7   A0A212ESE0   A0A3L8E314   A0A0L7QMK7   A0A1W4XDH0   D6W6I2   A0A158NVU7   A0A0J7NYR0   A0A1W4X2U0   A0A195C7D7   A0A195BB67   A0A1B6K6L4   A0A1Y1KI53   F4WMU2   A0A0M9A011   A0A1Y1KD17   A0A026WLD5   A0A1B6C942   A0A224XJ43   A0A023F2X0   A0A0C9PZY2   A0A0C9QAF7   A0A2H8TF21   J9JQ68   A0A146M4S1   A0A1B6CPE6   A0A2S2PR88   A0A2S2Q3V2   A0A0U3IZJ2   E0VYK9   T1HVZ3   A0A154PKK4   A0A1J1J6U3   A0A182QYK6   A0A1J1J525   B0WJF5   A0A151J504   A0A1I8JVZ3   A0A182LC51   A0A088A4F4   A0A1S4GGZ1   Q5TTJ6   A0A182U4Y9   A0A2C9GQG7   A0A182UVU8   E9INR0   A0A195EWL7   A0A232EMX8   A0A151WPX0   A0A182LZD6   W5JVS5   A0A1I8JW45   A0A3F2YSE5   A0A1S4GGY3   F5HKZ1   Q17J18   E2A9R7   A0A182H093   A0A084VKS5   A0A067RG01   E9FS22   A0A0P6DKL4   A0A0P6ENA3   A0A0P5HSF2   A0A0P5VR39   A0A0P6AQB5   Q17BM1   A0A0P5DHL5   A0A0P5WVM3   A0A164YGT7   A0A0P6DJA9   A0A0P5U328   A0A1L8DJF7   A0A1L8DJG4   A0A0L0CAR6   A0A0K8VZG5   A0A034VJE0   A0A0A1WV42   A0A0P5CL91   A0A1I8M3C9   A0A1I8NXE3   A0A0P5TI12   A0A1I8M2A8   A0A0N8CJ71   A0A1L8DJR7   A0A131Z5C6   B4LZ96   A0A224YMV3   A0A147BNF1  

PDB

3GQI     E-value=4.58006e-116,     Score=1072

KEGG

732849    no KO assigned | (RefSeq) Btl; fibroblast growth factor receptor

GO

GO:0005007   GO:0008284   GO:0016021   GO:0005524   GO:0004714   GO:0005887   GO:0043235   GO:0007169   GO:0008270   GO:0005634   GO:0003677   GO:0005777   GO:0007031   GO:0005515   GO:0004713   GO:0006468   GO:0008543   GO:0004672   GO:0048384  

Subcellular location

Nucleus  

Length:

797

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

36.9403399999999

Exp number, first 60 AAs:

0

Total prob of N-in:

0.14633

outside

1  -  368

TMhelix

369  -  391

inside

392  -  797

 

 

Pi

244.355745

Theta

168.68045

Tajima's D

1.138418

CLR

0.561531

CSRT

0.697365131743413

Interpretation

Uncertain