Gene

KWMTBOMO03808

Pre Gene Modal

BGIBMGA010081

Annotation

PREDICTED:_protein_tipE_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr7(+):2352724-2357873      View in EpiBrowser

Full name

Protein tipE      

Alternative Name

Temperature-induced paralytic E

Location in the cell

PlasmaMembrane   Reliability : 3.072

CDS

ATGGCCGACGAAGAGAAAATCCCTCCGACCTTTCTTGAGAAACTCCTATTCTACACAACAGCCTCCTTCGTTCTTCTTGCCACGTTCAGCCTATTCGCCTTTCTATTCTTAGTGCCATTTGTGATTGAACCAGCTTTCACTACGATATTCATGCAATTCGATCCTATAGGAGCTTTGTGTGTTACCACCCAAGTTAAACATTTGGTCGGAGCGAGCAATTGCACGTGGGCGTCCTGCAGGGAGGGCTGCACTAAAGATCTATTTGAATGCACACAAATTAGGGTCAGCTATAAACTGGGTAATTCATCTAATGTTACTGAAGAGGAAGTTGAAAATCTTATCAGAGTAGAGAGGGCTCTCAGGAATGATTACGACTATGAGAACGAGGTAGCTGCTGATAAGTCTTATCCAGATATGGGCGAGAGGGATGACTTGCCTGAACCGTATCCAACCGGGCTACAAGGGAACGACTCGGAATGGTATTTTACCGGGGCCCGTTTGTTTCCTAACGTGAAAGGTTGCGGTTATCCTCCTATATTGAACTGCACAATATTCTACGGAAAATATAGGCCTATTGGCACCAACTTCACTTGCTACTATAGCCGGGTGGATCCGGGCTTGGTTATCACCGAACTGGACATGTGGCAGAACACTCTGAACTTGGTGTACGCGATGGCCATACCAATACCGTCATTCTTTATCTCCGTCATATATTTGACGTTCGCTTACTTCAAAATTTATAATACTGAAGATGAATCCGAGCAGGCGCCTCTGAAGAGTGACGCTGAGGCTATGGCCACCGGTGACGATGAGAAACCAACGACCCCAGGGTCTGATACGTTTAGAGAAGATCTCGCATGTTTCGGTCACCAATTAAAGATGCAACTAGCCAACGATAAGCCTAAAGACGGCTTCGAGTCCAATAGTCCACCCATTTCCAATTCTGCCTCACTGTCTGGGACCAAGTCGTCATTCGTGAACGCCTAA

Protein

MADEEKIPPTFLEKLLFYTTASFVLLATFSLFAFLFLVPFVIEPAFTTIFMQFDPIGALCVTTQVKHLVGASNCTWASCREGCTKDLFECTQIRVSYKLGNSSNVTEEEVENLIRVERALRNDYDYENEVAADKSYPDMGERDDLPEPYPTGLQGNDSEWYFTGARLFPNVKGCGYPPILNCTIFYGKYRPIGTNFTCYYSRVDPGLVITELDMWQNTLNLVYAMAIPIPSFFISVIYLTFAYFKIYNTEDESEQAPLKSDAEAMATGDDEKPTTPGSDTFREDLACFGHQLKMQLANDKPKDGFESNSPPISNSASLSGTKSSFVNA

Description

Enhances para sodium channel function. Required during pupal development to rescue adult paralysis and also protects adult flies against heat-induced lethality.

Keywords

Complete proteome   Glycoprotein   Membrane   Reference proteome   Transmembrane   Transmembrane helix  

Feature

chain  Protein tipE

Uniprot

H9JKN0   A0A3S2LUB4   A0A2H1VE86   A0A2A4JVK2   A0A1C9HJF5   A0A212F9B3   + More
A0A194QEW5   A0A194RNY5   A0A0L7L9Y4   A0A2A4JUK1   U3GPB8   A0A1W4WKP3   A0A1B6DPF9   A0A2J7RPJ4   A0A310SHL1   A0A067QXZ1   A0A0Y0GW99   A0A088A7P9   A0A1Y1LN36   A0A3L8DZA7   E2BUU4   A0A158NJJ8   E9I9B6   A0A2P8XF56   E2A570   A0A2A3ENP1   A0A195F1J4   A0A151WJ86   A0A154PAU7   N6U6I2   A0A0A9XCZ5   A0A0A9XHV8   D6W8C5   T1HDH6   A0A336LZL0   A0A1B0CX46   A0A232F3B8   V9ID25   B4LB99   A0A1J1HWK3   E0VWJ9   P48613   A0A1W4W659   A0A195BFR0   B4HU17   A0A0J9RNL4   B3NG52   B4PHR2   B3M4W6   A0A1S3D2V6   A0A3B0K235   B4H7W4   Q29D71   A0A195CAH4   B4L9C6   B4J1F7   A0A1I8PYK2   A0A1I8PYM6   B4QQH2   A0A2S2NYM8   X1WP79   A0A1V0CJZ5   A0A0P5YZD7  

Pubmed

19121390    22118469    26354079    26227816    24845553    26202396    + More
28004739    30249741    20798317    21347285    21282665    29403074    23537049    25401762    26823975    18362917    19820115    28648823    17994087    18057021    20566863    7553842    10731132    12537572    12537569    22936249    17550304    15632085    23185243   

EMBL

BABH01024828    RSAL01000215    RVE44136.1    ODYU01002075    SOQ39127.1    NWSH01000549    + More
PCG75718.1    KU739069    AOO86803.1    AGBW02009597    OWR50345.1    KQ459167    KPJ03490.1    KQ460118    KPJ17731.1    JTDY01002018    KOB72313.1    PCG75717.1    KC992733    AGT98549.1    GEDC01009751    JAS27547.1    NEVH01001358    PNF42753.1    KQ761164    OAD58097.1    KK852829    KDR15345.1    KT455381    AMB38676.1    GEZM01054903    JAV73345.1    QOIP01000003    RLU25138.1    GL450757    EFN80530.1    ADTU01017981    GL761765    EFZ22843.1    PYGN01002378    PSN30612.1    GL436875    EFN71413.1    KZ288203    PBC33337.1    KQ981856    KYN34445.1    KQ983045    KYQ47891.1    KQ434849    KZC08504.1    APGK01047144    KB741077    KB632384    ENN74162.1    ERL94296.1    GBHO01026951    JAG16653.1    GBHO01026949    GBRD01002376    GDHC01019041    JAG16655.1    JAG63445.1    JAP99587.1    KQ971307    EFA10931.2    ACPB03015640    UFQS01000257    UFQT01000257    SSX02084.1    SSX22461.1    AJWK01033191    AJWK01033192    NNAY01001069    OXU25254.1    JR038322    AEY58209.1    CH940647    EDW68663.2    KRF83962.1    KRF83963.1    KRF83964.1    CVRI01000029    CRK92487.1    DS235822    EEB17755.1    U27561    AE014296    AY060317    KQ976490    KYM83420.1    CH480817    EDW50438.1    CM002912    KMY97525.1    KMY97526.1    KMY97527.1    KMY97528.1    KMY97529.1    KMY97530.1    CH954178    EDV50881.1    KQS43564.1    KQS43565.1    KQS43566.1    KQS43567.1    CM000159    EDW93371.1    KRK01140.1    KRK01141.1    KRK01142.1    KRK01143.1    KRK01144.1    CH902618    EDV40540.1    KPU78623.1    OUUW01000002    SPP77448.1    CH479219    EDW34754.1    CH379070    EAL30543.1    KRT09039.1    KRT09040.1    KQ978081    KYM97113.1    CH934399    CH933816    EDW05404.1    EDW17301.1    KRG07718.1    CH916366    EDV95848.1    CM000363    EDX09178.1    GGMR01009668    MBY22287.1    ABLF02030064    KY476317    ARA68389.1    GDIP01051261    JAM52454.1   

Proteomes

UP000005204    UP000283053    UP000218220    UP000007151    UP000053268    UP000053240    + More
UP000037510    UP000192223    UP000235965    UP000027135    UP000005203    UP000279307    UP000008237    UP000005205    UP000245037    UP000000311    UP000242457    UP000078541    UP000075809    UP000076502    UP000019118    UP000030742    UP000007266    UP000015103    UP000092461    UP000215335    UP000008792    UP000183832    UP000009046    UP000000803    UP000192221    UP000078540    UP000001292    UP000008711    UP000002282    UP000007801    UP000079169    UP000268350    UP000008744    UP000001819    UP000078542    UP000009192    UP000001070    UP000095300    UP000000304    UP000007819   

PRIDE

H9JKN0    P48613   

Pfam

PF16972   TipE        + More
PF11069   DUF2870

Interpro

IPR031578   TipE        + More
IPR021298   CFAP298       

ProteinModelPortal

H9JKN0   A0A3S2LUB4   A0A2H1VE86   A0A2A4JVK2   A0A1C9HJF5   A0A212F9B3   + More
A0A194QEW5   A0A194RNY5   A0A0L7L9Y4   A0A2A4JUK1   U3GPB8   A0A1W4WKP3   A0A1B6DPF9   A0A2J7RPJ4   A0A310SHL1   A0A067QXZ1   A0A0Y0GW99   A0A088A7P9   A0A1Y1LN36   A0A3L8DZA7   E2BUU4   A0A158NJJ8   E9I9B6   A0A2P8XF56   E2A570   A0A2A3ENP1   A0A195F1J4   A0A151WJ86   A0A154PAU7   N6U6I2   A0A0A9XCZ5   A0A0A9XHV8   D6W8C5   T1HDH6   A0A336LZL0   A0A1B0CX46   A0A232F3B8   V9ID25   B4LB99   A0A1J1HWK3   E0VWJ9   P48613   A0A1W4W659   A0A195BFR0   B4HU17   A0A0J9RNL4   B3NG52   B4PHR2   B3M4W6   A0A1S3D2V6   A0A3B0K235   B4H7W4   Q29D71   A0A195CAH4   B4L9C6   B4J1F7   A0A1I8PYK2   A0A1I8PYM6   B4QQH2   A0A2S2NYM8   X1WP79   A0A1V0CJZ5   A0A0P5YZD7  

KEGG

101737011    no KO assigned | (RefSeq) protein tipE

GO

GO:0016021   GO:0003352   GO:0017080   GO:0002028   GO:0005887   GO:0045433   GO:0034605   GO:0005248   GO:0005886   GO:0006814  

PANTHER

PTHR12335  

Subcellular location

Membrane  

Length:

328

Number of predicted TMHs:

2

Exp number of AAs in TMHs:

46.18627

Exp number, first 60 AAs:

23.23509

Total prob of N-in:

0.15481

POSSIBLE N-term signal

sequence

outside

1  -  19

TMhelix

20  -  42

inside

43  -  218

TMhelix

219  -  241

outside

242  -  328

 

 

Pi

288.582645

Theta

207.680042

Tajima's D

1.36796

CLR

0.364004

CSRT

0.758562071896405

Interpretation

Uncertain