Gene
KWMTBOMO03795
Pre Gene Modal
BGIBMGA010076
Annotation
tachykinin_precursor_[Bombyx_mori]
Full name
Tachykinins
Alternative Name
dTk
AmTRP
Tachykinin-related peptide
AmTRP
Tachykinin-related peptide
Location in the cell
Cytoplasmic Reliability : 1.414 Nuclear Reliability : 1.987
Sequence
CDS
ATGGGGACCTACAGAGCCTGTTTAGTACTACTGATTCTGCAAGTCATCTCCATCGCGACGGCTCAGGAAATGATAAAACGTATCCCCCAGGGTTTCTTGGGAATGCGCGGGAAGAAACACGAAGACGACAGCTCCGAGCAGTACTACAAGCGAAAGCCCCAGTTCTTCGTCGGAGTCAAGGGCAAGAAGAACTTCTACGACTACCTGGAAAACCCTGACGGATACTTCAAAAGGGCTCCGCTAGGCTTCACAGGTGTCAGAGGCAAAAAAGAGGACATGTCTTCCGAATACCAGTACTATCCATACGAAGCATTGAAGCGCGATGGGTCTTTGATAGGCCAAATCGAATATACCTCCGCGGAGCACATCAACGACGGCCAATACCCGATTCTCAATGATATCTTGAACGAGTATTTACAGAAGCTCGAGCGTCAAGAAACGAACAGCGATACCAACGAGACAGAAGAACAACGGATCACGAACGAAGTGGAGAAACGCGCTGCGAACATGCACCAGTTTTACGGCGTGCGAGGGAAGAAATCTGTCGACAACAAAAGACCATACGACTTGAGCATCCGCGGGAAATTCATCGGGGTCCGCGGCAAGAAGGACGTAAAGAACAGCAACGGTAAAGAAATCAAGTTTCTACTGAGCCGCCCGTTCCCGAAGAGGAGGGGGCAGATGGGATTCTTCGGGATGCGCGGCAAGAAGTGGATTGATGTATCGAGCCCTGAGATGGAGATCCCTAACTAA
Protein
MGTYRACLVLLILQVISIATAQEMIKRIPQGFLGMRGKKHEDDSSEQYYKRKPQFFVGVKGKKNFYDYLENPDGYFKRAPLGFTGVRGKKEDMSSEYQYYPYEALKRDGSLIGQIEYTSAEHINDGQYPILNDILNEYLQKLERQETNSDTNETEEQRITNEVEKRAANMHQFYGVRGKKSVDNKRPYDLSIRGKFIGVRGKKDVKNSNGKEIKFLLSRPFPKRRGQMGFFGMRGKKWIDVSSPEMEIPN
Summary
Description
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Stimulates gut muscle contractions (PubMed:10801863). Required for the response to the male sex pheromone CH503 which is transferred from males to females during mating and inhibits courtship behavior by other males (PubMed:26083710). The Gr68a gustatory receptor is required for detection of the pheromone and Gr68a-expressing neurons in the male foreleg relay signals to the suboesophageal zone (SEZ) which leads to courtship suppression through release of tachykinin from a cluster of 8-10 neurons in the SEZ (PubMed:26083710).
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Associated with sex-specific or age/division of labor-selective behavior and/or physiology of honeybees.
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Stimulates gut muscle contractions (PubMed:10801863). Required for the response to the male sex pheromone CH503 which is transferred from males to females during mating and inhibits courtship behavior by other males (PubMed:26083710). The Gr68a gustatory receptor is required for detection of the pheromone and Gr68a-expressing neurons in the male foreleg relay signals to the suboesophageal zone (SEZ) which leads to courtship suppression through release of tachykinin from a cluster of 8-10 neurons in the SEZ (PubMed:26083710).
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Associated with sex-specific or age/division of labor-selective behavior and/or physiology of honeybees.
Similarity
Belongs to the tachykinin family.
Keywords
Amidation
Cleavage on pair of basic residues
Direct protein sequencing
Neuropeptide
Secreted
Signal
Complete proteome
Reference proteome
Behavior
Neurotransmitter
Feature
peptide Tachykinin-related peptide 1
Uniprot
B3IUD3
H9JKM5
M4QCG2
C0HKW2
A0A0S1U0D6
A0A385H907
+ More
A0A3S2PA71 A0A2H1WBK7 A0A1E1WRL7 A0A411EVR5 A0A0L7KWR7 A0A194RJL3 A0A212EKY3 A0A194QJ49 D6WWT8 A0A139WD40 A0A1Y1NGA9 A0A139WD30 A0A151IDB2 K7IYE7 Q4G307 A0A151WED9 A0A232EYK0 F4WJJ0 E2AIS8 A0A026VYK5 A0A3L8DZ37 A0A195FGQ0 A0A195BDR0 A0A1I8MB65 A0A1I8MB66 Q4G308 I2HB50 U4U5I7 A0A143WDS4 A0A2P8YTC7 A0A151J3Y5 E9J6D6 A0A158NBI4 A0A336LSE9 A0A1J1IGC0 A0A1L8DPL4 A0A336LTG1 A0A336LPQ6 A0A1L8DQE4 A0A0L7RI45 A0A224XNR7 B4NA52 V9ILA2 A0A2A3EK73 C6K794 A0A1Y1DBG8 A0A2K8JMB2 A0A0C9R9M3 A0A2U9PFT0 A0A3Q0JJI7 B4K5M0 A0A067R6E3 Q9VGE8 B4QTI3 A0A0C9RQT7 B4HHI6 Q868G6 A0A034WCZ9 A0A0B4KFT7 B4LWG8 A0A1B6D9J8 W8AP88 U3U907 A0A088ACT0 A0A1Q1MKF7 A0A3S8RK58 A0A1B6MAP8 B4JT74
A0A3S2PA71 A0A2H1WBK7 A0A1E1WRL7 A0A411EVR5 A0A0L7KWR7 A0A194RJL3 A0A212EKY3 A0A194QJ49 D6WWT8 A0A139WD40 A0A1Y1NGA9 A0A139WD30 A0A151IDB2 K7IYE7 Q4G307 A0A151WED9 A0A232EYK0 F4WJJ0 E2AIS8 A0A026VYK5 A0A3L8DZ37 A0A195FGQ0 A0A195BDR0 A0A1I8MB65 A0A1I8MB66 Q4G308 I2HB50 U4U5I7 A0A143WDS4 A0A2P8YTC7 A0A151J3Y5 E9J6D6 A0A158NBI4 A0A336LSE9 A0A1J1IGC0 A0A1L8DPL4 A0A336LTG1 A0A336LPQ6 A0A1L8DQE4 A0A0L7RI45 A0A224XNR7 B4NA52 V9ILA2 A0A2A3EK73 C6K794 A0A1Y1DBG8 A0A2K8JMB2 A0A0C9R9M3 A0A2U9PFT0 A0A3Q0JJI7 B4K5M0 A0A067R6E3 Q9VGE8 B4QTI3 A0A0C9RQT7 B4HHI6 Q868G6 A0A034WCZ9 A0A0B4KFT7 B4LWG8 A0A1B6D9J8 W8AP88 U3U907 A0A088ACT0 A0A1Q1MKF7 A0A3S8RK58 A0A1B6MAP8 B4JT74
Pubmed
19121390
29466015
30171635
26227816
26354079
22118469
+ More
18362917 19820115 28004739 20075255 15978042 28648823 21719571 20798317 25641051 24508170 30249741 25315136 22448224 23537049 26706852 29403074 21282665 21347285 17994087 20958806 24845553 10801863 10731132 12537572 12537569 21214272 26083710 12752663 17068263 25348373 12537568 12537573 12537574 16110336 17569856 17569867 24495485 23932938 27923683 30467353
18362917 19820115 28004739 20075255 15978042 28648823 21719571 20798317 25641051 24508170 30249741 25315136 22448224 23537049 26706852 29403074 21282665 21347285 17994087 20958806 24845553 10801863 10731132 12537572 12537569 21214272 26083710 12752663 17068263 25348373 12537568 12537573 12537574 16110336 17569856 17569867 24495485 23932938 27923683 30467353
EMBL
AB298929
BAG50368.1
BABH01024789
KC340939
AGH25571.1
KT005994
+ More
ALM30345.1 MH028130 AXY04299.1 RSAL01000151 RVE45744.1 ODYU01007564 SOQ50440.1 GDQN01009384 GDQN01001578 JAT81670.1 JAT89476.1 MH347492 QBA82177.1 JTDY01004992 KOB67499.1 KQ460118 KPJ17742.1 AGBW02014179 OWR42135.1 KQ459167 KPJ03481.1 KQ971361 EFA09176.2 KYB25860.1 GEZM01006654 JAV95665.1 KYB25859.1 KQ977978 KYM98394.1 AY766012 AAX11212.1 KQ983238 KYQ46238.1 NNAY01001570 OXU23566.1 GL888184 EGI65606.1 GL439874 EFN66667.1 KK107574 EZA48740.1 QOIP01000002 RLU25704.1 KQ981606 KYN39568.1 KQ976509 KYM82693.1 AY766011 AAX11211.2 BK008420 DAA35084.1 KB632155 ERL89164.1 LN901334 CUT08829.1 PYGN01000372 PSN47497.1 KQ980230 KYN17141.1 GL768245 EFZ11618.1 ADTU01000331 ADTU01000332 ADTU01000333 ADTU01000334 ADTU01000335 UFQT01000100 SSX19911.1 CVRI01000048 CRK98588.1 GFDF01005688 JAV08396.1 SSX19909.1 SSX19910.1 GFDF01005477 JAV08607.1 KQ414590 KOC70401.1 GFTR01003692 JAW12734.1 CH964232 EDW80695.2 JR050386 AEY61261.1 KZ288234 PBC31431.1 ACPB03026326 GQ162785 ACS45389.1 LC271567 BAX90007.1 KY031198 ATU82949.1 GBYB01009622 JAG79389.1 MG550189 AWT50623.1 CH933806 EDW14057.1 KK852669 KDR18855.1 AF248040 AE014297 AY071179 BT044493 AAF54735.1 AAF89172.1 AAL48801.1 CM000364 EDX13288.1 GBYB01009621 JAG79388.1 CH480815 EDW42525.1 AB073995 AB073996 AB073997 AB073998 BAC76402.1 GAKP01005496 JAC53456.1 AGB95875.1 CH940650 EDW66605.1 GEDC01014935 JAS22363.1 GAMC01020237 JAB86318.1 AB817282 BAO00979.1 KX671125 AQM36730.1 MH311659 AZK31369.1 GEBQ01006964 JAT33013.1 CH916373 EDV94964.1
ALM30345.1 MH028130 AXY04299.1 RSAL01000151 RVE45744.1 ODYU01007564 SOQ50440.1 GDQN01009384 GDQN01001578 JAT81670.1 JAT89476.1 MH347492 QBA82177.1 JTDY01004992 KOB67499.1 KQ460118 KPJ17742.1 AGBW02014179 OWR42135.1 KQ459167 KPJ03481.1 KQ971361 EFA09176.2 KYB25860.1 GEZM01006654 JAV95665.1 KYB25859.1 KQ977978 KYM98394.1 AY766012 AAX11212.1 KQ983238 KYQ46238.1 NNAY01001570 OXU23566.1 GL888184 EGI65606.1 GL439874 EFN66667.1 KK107574 EZA48740.1 QOIP01000002 RLU25704.1 KQ981606 KYN39568.1 KQ976509 KYM82693.1 AY766011 AAX11211.2 BK008420 DAA35084.1 KB632155 ERL89164.1 LN901334 CUT08829.1 PYGN01000372 PSN47497.1 KQ980230 KYN17141.1 GL768245 EFZ11618.1 ADTU01000331 ADTU01000332 ADTU01000333 ADTU01000334 ADTU01000335 UFQT01000100 SSX19911.1 CVRI01000048 CRK98588.1 GFDF01005688 JAV08396.1 SSX19909.1 SSX19910.1 GFDF01005477 JAV08607.1 KQ414590 KOC70401.1 GFTR01003692 JAW12734.1 CH964232 EDW80695.2 JR050386 AEY61261.1 KZ288234 PBC31431.1 ACPB03026326 GQ162785 ACS45389.1 LC271567 BAX90007.1 KY031198 ATU82949.1 GBYB01009622 JAG79389.1 MG550189 AWT50623.1 CH933806 EDW14057.1 KK852669 KDR18855.1 AF248040 AE014297 AY071179 BT044493 AAF54735.1 AAF89172.1 AAL48801.1 CM000364 EDX13288.1 GBYB01009621 JAG79388.1 CH480815 EDW42525.1 AB073995 AB073996 AB073997 AB073998 BAC76402.1 GAKP01005496 JAC53456.1 AGB95875.1 CH940650 EDW66605.1 GEDC01014935 JAS22363.1 GAMC01020237 JAB86318.1 AB817282 BAO00979.1 KX671125 AQM36730.1 MH311659 AZK31369.1 GEBQ01006964 JAT33013.1 CH916373 EDV94964.1
Proteomes
UP000005204
UP000283053
UP000037510
UP000053240
UP000007151
UP000053268
+ More
UP000007266 UP000078542 UP000002358 UP000075809 UP000215335 UP000007755 UP000000311 UP000053097 UP000279307 UP000078541 UP000078540 UP000095301 UP000030742 UP000245037 UP000078492 UP000005205 UP000183832 UP000053825 UP000007798 UP000242457 UP000015103 UP000079169 UP000009192 UP000027135 UP000000803 UP000000304 UP000001292 UP000005203 UP000008792 UP000001070
UP000007266 UP000078542 UP000002358 UP000075809 UP000215335 UP000007755 UP000000311 UP000053097 UP000279307 UP000078541 UP000078540 UP000095301 UP000030742 UP000245037 UP000078492 UP000005205 UP000183832 UP000053825 UP000007798 UP000242457 UP000015103 UP000079169 UP000009192 UP000027135 UP000000803 UP000000304 UP000001292 UP000005203 UP000008792 UP000001070
Pfam
PF00201 UDPGT
Interpro
IPR002213
UDP_glucos_trans
ProteinModelPortal
B3IUD3
H9JKM5
M4QCG2
C0HKW2
A0A0S1U0D6
A0A385H907
+ More
A0A3S2PA71 A0A2H1WBK7 A0A1E1WRL7 A0A411EVR5 A0A0L7KWR7 A0A194RJL3 A0A212EKY3 A0A194QJ49 D6WWT8 A0A139WD40 A0A1Y1NGA9 A0A139WD30 A0A151IDB2 K7IYE7 Q4G307 A0A151WED9 A0A232EYK0 F4WJJ0 E2AIS8 A0A026VYK5 A0A3L8DZ37 A0A195FGQ0 A0A195BDR0 A0A1I8MB65 A0A1I8MB66 Q4G308 I2HB50 U4U5I7 A0A143WDS4 A0A2P8YTC7 A0A151J3Y5 E9J6D6 A0A158NBI4 A0A336LSE9 A0A1J1IGC0 A0A1L8DPL4 A0A336LTG1 A0A336LPQ6 A0A1L8DQE4 A0A0L7RI45 A0A224XNR7 B4NA52 V9ILA2 A0A2A3EK73 C6K794 A0A1Y1DBG8 A0A2K8JMB2 A0A0C9R9M3 A0A2U9PFT0 A0A3Q0JJI7 B4K5M0 A0A067R6E3 Q9VGE8 B4QTI3 A0A0C9RQT7 B4HHI6 Q868G6 A0A034WCZ9 A0A0B4KFT7 B4LWG8 A0A1B6D9J8 W8AP88 U3U907 A0A088ACT0 A0A1Q1MKF7 A0A3S8RK58 A0A1B6MAP8 B4JT74
A0A3S2PA71 A0A2H1WBK7 A0A1E1WRL7 A0A411EVR5 A0A0L7KWR7 A0A194RJL3 A0A212EKY3 A0A194QJ49 D6WWT8 A0A139WD40 A0A1Y1NGA9 A0A139WD30 A0A151IDB2 K7IYE7 Q4G307 A0A151WED9 A0A232EYK0 F4WJJ0 E2AIS8 A0A026VYK5 A0A3L8DZ37 A0A195FGQ0 A0A195BDR0 A0A1I8MB65 A0A1I8MB66 Q4G308 I2HB50 U4U5I7 A0A143WDS4 A0A2P8YTC7 A0A151J3Y5 E9J6D6 A0A158NBI4 A0A336LSE9 A0A1J1IGC0 A0A1L8DPL4 A0A336LTG1 A0A336LPQ6 A0A1L8DQE4 A0A0L7RI45 A0A224XNR7 B4NA52 V9ILA2 A0A2A3EK73 C6K794 A0A1Y1DBG8 A0A2K8JMB2 A0A0C9R9M3 A0A2U9PFT0 A0A3Q0JJI7 B4K5M0 A0A067R6E3 Q9VGE8 B4QTI3 A0A0C9RQT7 B4HHI6 Q868G6 A0A034WCZ9 A0A0B4KFT7 B4LWG8 A0A1B6D9J8 W8AP88 U3U907 A0A088ACT0 A0A1Q1MKF7 A0A3S8RK58 A0A1B6MAP8 B4JT74
Ontologies
GO
Topology
Subcellular location
Secreted
SignalP
Position: 1 - 21,
Likelihood: 0.994963
Length:
250
Number of predicted TMHs:
1
Exp number of AAs in TMHs:
13.74773
Exp number, first 60 AAs:
13.74773
Total prob of N-in:
0.73086
POSSIBLE N-term signal
sequence
inside
1 - 6
TMhelix
7 - 25
outside
26 - 250
Population Genetic Test Statistics
Pi
207.749216
Theta
165.649768
Tajima's D
1.164327
CLR
0.168131
CSRT
0.705914704264787
Interpretation
Uncertain
