Gene

KWMTBOMO03772  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA010023

Annotation

PREDICTED:_trypsin-like_serine_protease_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr7(-):1402581-1406757      View in EpiBrowser

Location in the cell

Extracellular   Reliability : 2.996

CDS

ATGGCCTACCTCGCTTTTACCCTAACCTTGCTCGCAGCAGCTAGCTGCATCTCAGCCAACAACCTTGGCACTAGAGTGCCTATCAGTGACCGCCCCAGTTTGGCTCAAGTTGAAGTCGCCCTGGGCAACGTTTGGATCCAGCAGTGTGCTGGTGCCGTACTCACCAACTTCCATATCCTGTCTGTTGCCACTTGTTTCTCTGGAGCCTTCTACCGGCCCGATACTCGTCGTATTCGTCTCGGTTCTGACATACGAAATGAAGGCGGCTTGATCGTGAATGTGTTACTTGCCAATAACCATCACTCATTCGATCCCACGAATATGGCCAGCGATATTTCCGTTGTCCGTCTTAGTTCAGCAATCACCCTTGGTGGTAATATACAACAAGCCTCAGTCATCCTTCAAGGAGTACATGTGCCCCCTCGCTTAAGCGTCGAGCTCATCGGTTGGGGAAACACTCCGCAAGGAGGTGCAGTTACCGACGATAACCTATACGGTCTGAGCCTCACCACAGTAGACCGATACACCTGTAGGAGCAAATACGAAGACAGGGAAGTTACCAATACAATGCTTTGCTTTGGCTTACCCAGGGAGGGCGGTCGTGACTTTTTTACCCGTGACGTTGGTGCTCCCGTTTTCTATCAGAACGCTTTGATCAGTCTAATATCCTTCGGGGAATCTGATGCTAATAACGAGTACCCTCTGGTCGGTACCGGCATCAGCGATTACACGAACTGGATTATCGAAAACGCTGCTTCATAA

Protein

MAYLAFTLTLLAAASCISANNLGTRVPISDRPSLAQVEVALGNVWIQQCAGAVLTNFHILSVATCFSGAFYRPDTRRIRLGSDIRNEGGLIVNVLLANNHHSFDPTNMASDISVVRLSSAITLGGNIQQASVILQGVHVPPRLSVELIGWGNTPQGGAVTDDNLYGLSLTTVDRYTCRSKYEDREVTNTMLCFGLPREGGRDFFTRDVGAPVFYQNALISLISFGESDANNEYPLVGTGISDYTNWIIENAAS

Similarity

Belongs to the peptidase S1 family.

Uniprot

G8GBC4   H9JKH3   Q1HPT9   H9JKL1   H9JKL2   A0A1B1LTR2   + More
A0A2W1BN83   A0A2A4JTK1   A0A2H1W3R1   A0A2H1VGN5   C9W8I5   A0A0L7L5I1   E0W9N5   A0A1B0RHN8   O18439   A0A0M4M544   A0A2W1BN80   A0A2H1VGQ8   A0A2H1W591   A9P3S4   A0A2H1VIA8   A0A194QET8   A0A3S2N5V1   A0A2H1VGP3   B6D1Q8   A0A2A4JTX8   A0A194QD40   B4X9A2   A0A1E1WML3   A0A2A4JTP3   A0A2W1BJP2   C9W8I6   B1NLD8   A0A2H1W3L1   A0A0M4MT18   A0A2W1BTM0   Q9U4I4   B4X9A3   A0A2A4JUR5   B4X9A4   A0A2H1VGQ2   A0A0L7L171   C9W8J1   A0A194QJ28   A0A437BTC7   A0A2H1WEE4   I7C7Q2   I7DEJ5   A0A2A4JSY0   A0A0L7KYH0   Q9U4I5   A0A212EW56   I6TEW4   A0A2H1VGM7   A0A089RSX5   A0A2A4JUT0   A0A194QDC5   A0A1E1WB94   B6CME9   A0A0N1I8C7   A0A2W1BP62   A5CG75   B1NLE4   A0A1E1W498   A0A0L7L163   Q6R560   Q56IB2   Q9NB89   Q56IB0   B6D1Q7   Q9NB81   Q56IB1   O45047   A0A194QDG3   A0A437BSH3   A0A194QD45   A0A0N1PGP3   A0A223AIS8   Q4L1L0   Q4L1L4   A0A2H1VIX1   Q4L1L5   A0A2W1BJK7   H9JKL0   A0A212FMZ9   A0A2W1BKR8   Q9NB80   Q4L1L9   G9F9K6   A0A2W1BF78   A0A437B8S1   A0A194PVB6   A0A2A4K5G7   B4X995   A0A2W1BKF9   A0A0L7L2M0   V9LL27   A0A2A4K5I4   Q4L1L3   A0A2A4K648  

Pubmed

19121390    28756777    20824821    26227816    9404008    19146482    + More
26354079    19133073    18314941    10989289    22824002    22118469    18760362    18634789    15944081    16469064    11267903    10646971    15979001    22432944   

EMBL

BABH01024734    JN120256    AER70119.1    BABH01024730    DQ443313    KM027249    + More
ABF51402.1    AIU94618.1    BABH01024727    BABH01024728    BABH01024729    KX380991    ANS56507.1    KZ150010    PZC75085.1    NWSH01000631    PCG75149.1    ODYU01006115    SOQ47673.1    ODYU01002467    SOQ39995.1    FJ205431    ACR15998.2    JTDY01002795    KOB70712.1    FJ205419    ADM35106.1    KM360185    AKH49601.1    Y12274    CAA72953.1    KR024672    ALE15214.1    PZC75084.1    SOQ39996.1    SOQ47674.1    EF104913    ABP96915.1    SOQ39994.1    KQ459167    KPJ03460.1    RSAL01000347    RVE42309.1    SOQ39998.1    EU673451    ACI45414.1    PCG75148.1    KPJ03458.1    EF531638    ABR88249.1    GDQN01011173    GDQN01002795    JAT79881.1    JAT88259.1    PCG75146.1    PZC75088.1    FJ205433    ACR15999.2    EF600053    ABU98618.1    PZC75086.1    SOQ47675.1    KR024671    ALE15213.1    PZC75083.1    AF173498    AAF24228.1    EF531639    EF531641    ABR88250.1    ABR88252.1    PCG75150.1    EF531640    ABR88251.1    SOQ39997.1    JTDY01003642    KOB69232.1    FJ205440    ACR16004.1    KPJ03461.1    RSAL01000013    RVE53439.1    ODYU01007983    SOQ51222.1    JN793548    AFO68328.1    JN793549    AFO68329.1    PCG75147.1    JTDY01004416    KOB68185.1    AF173497    AAF24227.1    AGBW02012089    OWR45697.1    JQ904129    AFM77759.1    SOQ39999.1    KM083776    AIR09757.1    PCG75152.1    KPJ03462.1    GDQN01006776    JAT84278.1    EU325549    ACB54939.1    KQ460409    KPJ14944.1    PZC75087.1    AM690450    CAM84320.1    EF600059    ABU98624.1    GDQN01009270    JAT81784.1    KOB69233.1    AY513650    AAR98919.1    AY953065    AAX62038.1    AF261973    AAF74735.1    AY953064    AY953068    AAX62037.1    AAX63384.1    EU673450    ACI45413.1    AF261981    AAF74743.1    AY953066    AAX62039.1    AF045142    AAC02220.1    KPJ03459.1    RVE53438.1    KPJ03463.1    KPJ14943.1    KX951432    KY684226    ARR75600.1    ASS33865.1    AY587155    AAT95347.1    AY587151    AAT95343.1    ODYU01002820    SOQ40778.1    AY587150    AAT95342.1    KZ150104    PZC73447.1    BABH01024725    AGBW02007649    OWR55124.1    PZC73446.1    AF261982    AAF74744.1    AY587146    AAT95361.1    JN033751    JN315765    AEW46904.1    AFK64829.1    PZC73448.1    RSAL01000115    RVE46900.1    KQ459597    KPI95070.1    NWSH01000106    PCG79485.1    EF531631    EF531633    ABR88242.1    ABR88244.1    KZ149992    PZC75529.1    JTDY01003417    KOB69586.1    JQ340915    AFP74111.1    PCG79487.1    AY587152    AAT95344.1    PCG79486.1   

Proteomes

UP000005204    UP000218220    UP000037510    UP000053268    UP000283053    UP000007151    + More
UP000053240   

PRIDE

G8GBC4    H9JKH3    Q1HPT9    H9JKL1    H9JKL2    H9JKL0    + More

Pfam

PF00089   Trypsin        + More
PF00226   DnaJ
PF07743   HSCB_C

Interpro

IPR001254   Trypsin_dom        + More
IPR009003   Peptidase_S1_PA       
IPR018114   TRYPSIN_HIS       
IPR001314   Peptidase_S1A       
IPR033116   TRYPSIN_SER       
IPR012224   Pept_S1A_FX       
IPR004640   HscB       
IPR036386   HscB_C_sf       
IPR001623   DnaJ_domain       
IPR036869   J_dom_sf       
IPR009073   HscB_oligo_C       

SUPFAM

SSF50494   SSF50494        + More
SSF46565   SSF46565       
SSF47144   SSF47144       

Gene 3D

1.10.287.110     1.20.1280.20    

CDD

cd00190  Tryp_SPc
cd06257  DnaJ

ProteinModelPortal

G8GBC4   H9JKH3   Q1HPT9   H9JKL1   H9JKL2   A0A1B1LTR2   + More
A0A2W1BN83   A0A2A4JTK1   A0A2H1W3R1   A0A2H1VGN5   C9W8I5   A0A0L7L5I1   E0W9N5   A0A1B0RHN8   O18439   A0A0M4M544   A0A2W1BN80   A0A2H1VGQ8   A0A2H1W591   A9P3S4   A0A2H1VIA8   A0A194QET8   A0A3S2N5V1   A0A2H1VGP3   B6D1Q8   A0A2A4JTX8   A0A194QD40   B4X9A2   A0A1E1WML3   A0A2A4JTP3   A0A2W1BJP2   C9W8I6   B1NLD8   A0A2H1W3L1   A0A0M4MT18   A0A2W1BTM0   Q9U4I4   B4X9A3   A0A2A4JUR5   B4X9A4   A0A2H1VGQ2   A0A0L7L171   C9W8J1   A0A194QJ28   A0A437BTC7   A0A2H1WEE4   I7C7Q2   I7DEJ5   A0A2A4JSY0   A0A0L7KYH0   Q9U4I5   A0A212EW56   I6TEW4   A0A2H1VGM7   A0A089RSX5   A0A2A4JUT0   A0A194QDC5   A0A1E1WB94   B6CME9   A0A0N1I8C7   A0A2W1BP62   A5CG75   B1NLE4   A0A1E1W498   A0A0L7L163   Q6R560   Q56IB2   Q9NB89   Q56IB0   B6D1Q7   Q9NB81   Q56IB1   O45047   A0A194QDG3   A0A437BSH3   A0A194QD45   A0A0N1PGP3   A0A223AIS8   Q4L1L0   Q4L1L4   A0A2H1VIX1   Q4L1L5   A0A2W1BJK7   H9JKL0   A0A212FMZ9   A0A2W1BKR8   Q9NB80   Q4L1L9   G9F9K6   A0A2W1BF78   A0A437B8S1   A0A194PVB6   A0A2A4K5G7   B4X995   A0A2W1BKF9   A0A0L7L2M0   V9LL27   A0A2A4K5I4   Q4L1L3   A0A2A4K648  

PDB

1FXY     E-value=1.91053e-18,     Score=225

KEGG

100862795    K01312 trypsin [EC:3.4.21.4] | (RefSeq) trypsin-like serine protease

PATHWAY

04080    Neuroactive ligand-receptor interaction - Bombyx mori (domestic silkworm)

GO

GO:0004252   GO:0005509   GO:0007596   GO:0097428   GO:0001671   GO:0051259   GO:0051087   GO:0006508   GO:0006811   GO:0016020   GO:0007155   GO:0000049   GO:0004812   GO:0043039   GO:0042555   GO:0048384  

PANTHER

PTHR14021  

SignalP

Position:   1 - 19,         Likelihood:  0.973227

 

 

Length:

253

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

9.71664999999997

Exp number, first 60 AAs:

7.11481

Total prob of N-in:

0.16855

outside

1  -  253

 

 

Pi

156.449765

Theta

115.58697

Tajima's D

-0.742359

CLR

0.274332

CSRT

0.187090645467727

Interpretation

Uncertain