Gene

KWMTBOMO03722  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA009992

Annotation

PREDICTED:_EH_domain-containing_protein_3_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr7(-):138690-167645      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 3.695

CDS

ATGTTTAGTTGGCTTAAGAAAGAAGGTGAAAAAGCGGAAAATATTGAAAATGTCGTGGAAGGGCTCAAGAGGATTTACAAAACTAAACTGTTGCCTCTTGAGCTGCACTACCAGTTCCACGATTTCCATTCGCCGCAGCTCGAAGATCCAGATTTCGATGCCAAACCCATGATACTTCTCGTGGGACAGTACTCCACCGGTAAAACGACATTTATCAGGTATTTGCTAGAGAGAGATTTTCCGGGCATCCGTATTGGTCCAGAGCCGACTACAGATAGATTTATAGCCGTTATGTTCGACGAAAAAGAGGGCGTAATTCCGGGTAATGCGTTAGTAGTAGATCCGAAAAAACAGTTTCGACCATTGAGTAAATTTGGTAACGCCTTCCTGAACCGATTCCAGTGTTCAACTGTCACGTCGGACGTACTACGCGGGATCTCTATCGTTGACACACCCGGTATCCTATCTGGAGAGAAACAGCGTGTAGATCGCGGGTATGACTTTACTGGAGTATTGGAATGGTTTGCTGAGCGTGTTGACCGAATCATACTTTTGTTCGATGCTCACAAACTTGATATATCAGATGAATTTAGGCGCAGTATAGAGGCATTGAGAGGACATGATGATAAGATCCGAATTGTGCTCAACAAAGCTGATATGATAGATCATCAGCAGTTGATGCGTGTTTATGGAGCTCTGATGTGGTCACTGGGAAAAGTTTTACAAACTCCTGAGGTTGCTAGAGTGTACATTGGCTCATTTTGGGATGAGCCTCTCCGGTACGATGTTAATCGTCGACTTTTTGAAGATGAAGAACAAGATTTATTTAAAGACATGCAGTCTTTGCCAAGGAATGCTGCCCTGCGTAAACTAAACGACCTTATTAAAAGAGCACGACTTGCTAAGGTTCATGCATACATAGTCAATGAGTTAAGGAAAGAGATGCCTTCAATGTTTGGTAAAGATTCAAAAAAGAAAGATCTAATCAAGAATCTTGGTCAGGTTTATGATAAAATACAAAGAGAGCAGCAAATATCACCGGGAGACTTTCCAGATATTAAAAAAATGCAAGAGACCCTGGCCAATCATGACTTCACCAAGTTTCACCCCTTGAAACCCAAGTTGCTAGAAGTAGTGGACCACATGCTGGCAACGGACATTGCACGGCTCATGGATATGATTCCACAGGAGGACATCAACATTGTCAGTGAACCTCTGATAAAGGGTGGTGCTTTCGAAGGTGTAGAAGACCAGGTCTCACCATTCGGTTACGGTCGGGGCGAGGGCGTGGACGCCGGCCACGGTGACCCGGAATGGATCTGCAGCAAGGAGAAACCGAACTACGACCGAATCTTCCAATCTCTGAACCCGATCGACGGCAAAGTGACTGGCGCCGCCGCAAAGACAGAGATGGTGAAGTCGAAGCTGCCCAACTCTGTGCTCGGCAAGATTTGGAAGCTCTCCGACATCGACAAGGACGGCTTCCTGGACGAAGAGGAGTTTGCGCTCGCGATGCATCTCATCTCGGTGAAGGTGGACGGACACGACCTGCCCACCGAGCTGCCCTCGCACCTCGTGCCGCCCTCCAAACGGAACTGA

Protein

MFSWLKKEGEKAENIENVVEGLKRIYKTKLLPLELHYQFHDFHSPQLEDPDFDAKPMILLVGQYSTGKTTFIRYLLERDFPGIRIGPEPTTDRFIAVMFDEKEGVIPGNALVVDPKKQFRPLSKFGNAFLNRFQCSTVTSDVLRGISIVDTPGILSGEKQRVDRGYDFTGVLEWFAERVDRIILLFDAHKLDISDEFRRSIEALRGHDDKIRIVLNKADMIDHQQLMRVYGALMWSLGKVLQTPEVARVYIGSFWDEPLRYDVNRRLFEDEEQDLFKDMQSLPRNAALRKLNDLIKRARLAKVHAYIVNELRKEMPSMFGKDSKKKDLIKNLGQVYDKIQREQQISPGDFPDIKKMQETLANHDFTKFHPLKPKLLEVVDHMLATDIARLMDMIPQEDINIVSEPLIKGGAFEGVEDQVSPFGYGRGEGVDAGHGDPEWICSKEKPNYDRIFQSLNPIDGKVTGAAAKTEMVKSKLPNSVLGKIWKLSDIDKDGFLDEEEFALAMHLISVKVDGHDLPTELPSHLVPPSKRN

Similarity

Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
Belongs to the histidine acid phosphatase family.

Uniprot

A0A194QEQ2   A0A220K8I4   A0A3S2NZX2   E2AZE9   A0A151WJF0   A0A0J7N331   + More
A0A195CQM0   A0A2J7R596   E2C8F3   A0A026WV74   F4WGA5   A0A195B693   A0A158NI61   A0A232EL11   E9IB79   A0A195EGP8   A0A151JXC0   Q16T24   A0A1W4WR69   A0A023ETP5   A0A154P3I4   A0A1J1IJV4   U5EMK8   A0A2A3EAJ6   V9IMV7   A0A088A395   A0A1Q3FC31   B0WNC3   A0A411G820   A0A1Y1N381   A0A0T6AXK7   A0A084W7R4   A0A1Q3FC63   A0A0M9A7H5   K7J964   B4KC47   A0A310SEK6   Q7Q7M8   A0A1Y9GKD8   A0A182VJ75   A0A182LNL6   R4G5H8   Q8T6I0   A0A182Q189   Q8IGN0   B4MBB5   B4NI15   Q299V4   A0A034W1B4   A0A0L7QXR0   R4WJU9   B3M1W0   A0A0L0CSV7   B4QS70   B4HGF8   B3P472   Q8T8W3   B4PPE1   A0A2M4CTJ3   A0A2M3Z4V5   A0A336K5Q6   T1P861   A0A1L8ECI4   A0A1B0CRC7   A0A1I8PMV3   A0A139WP92   A0A1L8ECY2   A0A2M4AEW8   A0A3B0K9Z4   A0A1W4UMX8   A0A1L8DM80   A0A0K8VR18   A0A1S4GM49   E0VWS6   A0A0A1XQJ0   W8C0Q9   A0A0A9YYD3   A0A0P4VH63   D3TMZ1   A0A1A9VS50   A0A1A9ZGE4   A0A0K8TAD0   A0A1A9XDL2   A0A0A9Z0A3   A0A2M4AFA1   A0A0A9W3E3   A0A0P6I8F2   A0A0P5B0F6   A0A0K8SCA0   E9GJ29   N6T8R1   A0A0A9YXZ4   A0A0M4ECQ3   A0A0P5ZNQ1   A0A023FLZ2   V5HPU0   A0A0P6BUH4   A0A023GL46   A0A1E1X9N6   A0A131Y206  

Pubmed

26354079    28630352    20798317    24508170    21719571    21347285    + More
28648823    21282665    17510324    24945155    28004739    24438588    20075255    17994087    12364791    20966253    10731132    12537568    12537572    12537573    12537574    15155807    16110336    17569856    17569867    26109357    26109356    15632085    25348373    23691247    26108605    17550304    25315136    18362917    19820115    20566863    25830018    24495485    25401762    27129103    20353571    26823975    21292972    23537049    25765539    28503490   

EMBL

KQ459167    KPJ03425.1    MF319687    ASJ26401.1    RSAL01000013    RVE53411.1    + More
GL444207    EFN61188.1    KQ983039    KYQ47982.1    LBMM01011006    KMQ87085.1    KQ977481    KYN02409.1    NEVH01007392    PNF36009.1    GL453666    EFN75788.1    KK107111    EZA59004.1    GL888128    EGI66872.1    KQ976579    KYM80026.1    ADTU01016304    NNAY01003689    OXU19002.1    GL762111    EFZ22199.1    KQ978957    KYN27059.1    KQ981578    KYN39752.1    CH477661    EAT37607.1    GAPW01000883    JAC12715.1    KQ434809    KZC06431.1    CVRI01000054    CRL00034.1    GANO01000984    JAB58887.1    KZ288322    PBC28216.1    JR053683    AEY61994.1    GFDL01009904    JAV25141.1    DS232010    EDS31577.1    MH366186    QBB01995.1    GEZM01013851    GEZM01013850    JAV92289.1    LJIG01022673    KRT79319.1    ATLV01021281    ATLV01021282    ATLV01021283    ATLV01021284    KE525316    KFB46258.1    GFDL01009936    JAV25109.1    KQ435719    KOX78810.1    AAZX01002217    AAZX01010953    AAZX01014300    CH933806    EDW16920.2    KQ770178    OAD52669.1    AAAB01008952    EAA10568.5    APCN01005960    APCN01005961    ACPB03000063    GAHY01000560    JAA76950.1    AE014297    AF473822    AAF54856.2    AAL85325.1    AXCN02002206    BT001695    AAN71450.1    CH940656    EDW58386.2    CH964272    EDW83665.1    CM000070    EAL27597.4    GAKP01010480    GAKP01010478    JAC48474.1    KQ414704    KOC63336.1    AK417885    BAN21100.1    CH902617    EDV42220.2    JRES01000062    KNC34489.1    CM000364    EDX13166.1    CH480815    EDW42406.1    CH954181    EDV49317.1    AY075248    AAL68115.1    AAN13552.1    CM000160    EDW97147.1    GGFL01004407    MBW68585.1    GGFM01002737    MBW23488.1    UFQS01000109    UFQT01000109    SSW99771.1    SSX20151.1    KA644851    AFP59480.1    GFDG01002368    JAV16431.1    AJWK01024616    AJWK01024617    AJWK01024618    KQ971307    KYB29743.1    GFDG01002366    JAV16433.1    GGFK01006003    MBW39324.1    OUUW01000005    SPP80378.1    GFDF01006599    JAV07485.1    GDHF01033411    GDHF01011284    JAI18903.1    JAI41030.1    DS235824    EEB17832.1    GBXI01003934    GBXI01000693    JAD10358.1    JAD13599.1    GAMC01011347    GAMC01011346    GAMC01011345    JAB95209.1    GBHO01006998    GBHO01000480    JAG36606.1    JAG43124.1    GDKW01003733    JAI52862.1    EZ422793    ADD19069.1    GBRD01015427    GBRD01003333    JAG62488.1    GBHO01041262    GBHO01005705    GBRD01003337    GBRD01003336    GDHC01016107    GDHC01006801    JAG02342.1    JAG37899.1    JAG62484.1    JAQ02522.1    JAQ11828.1    GGFK01005997    MBW39318.1    GBHO01041265    GBHO01041260    JAG02339.1    JAG02344.1    GDIQ01008070    JAN86667.1    GDIP01206076    GDIQ01192614    GDIQ01120692    LRGB01001253    JAJ17326.1    JAK59111.1    KZS13220.1    GBRD01015426    GBRD01003335    JAG50400.1    GL732547    EFX80375.1    APGK01047050    KB741077    KB632384    ENN74083.1    ERL94214.1    GBHO01006995    GBHO01005712    GBRD01003338    GBRD01001426    JAG36609.1    JAG37892.1    JAG62483.1    CP012526    ALC45466.1    GDIP01041789    JAM61926.1    GBBK01002293    JAC22189.1    GANP01006706    JAB77762.1    GDIP01014121    JAM89594.1    GBBM01000812    JAC34606.1    GFAC01003220    JAT95968.1    GEFM01002879    JAP72917.1   

Proteomes

UP000053268    UP000283053    UP000000311    UP000075809    UP000036403    UP000078542    + More
UP000235965    UP000008237    UP000053097    UP000007755    UP000078540    UP000005205    UP000215335    UP000078492    UP000078541    UP000008820    UP000192223    UP000076502    UP000183832    UP000242457    UP000005203    UP000002320    UP000030765    UP000053105    UP000002358    UP000009192    UP000007062    UP000075840    UP000075903    UP000075882    UP000015103    UP000000803    UP000075886    UP000008792    UP000007798    UP000001819    UP000053825    UP000007801    UP000037069    UP000000304    UP000001292    UP000008711    UP000002282    UP000095301    UP000092461    UP000095300    UP000007266    UP000268350    UP000192221    UP000009046    UP000078200    UP000092445    UP000092443    UP000076858    UP000000305    UP000019118    UP000030742    UP000092553   

PRIDE

Q8T6I0    Q8IGN0    Q8T8W3   

Pfam

PF16880   EHD_N        + More
PF12763   EF-hand_4
PF00350   Dynamin_N
PF18150   DUF5600
PF00328   His_Phos_2

Interpro

IPR000261   EH_dom        + More
IPR031692   EHD_N       
IPR018247   EF_Hand_1_Ca_BS       
IPR022812   Dynamin_SF       
IPR040990   DUF5600       
IPR029952   EHD4       
IPR027417   P-loop_NTPase       
IPR002048   EF_hand_dom       
IPR011992   EF-hand-dom_pair       
IPR030381   G_DYNAMIN_dom       
IPR029033   His_PPase_superfam       
IPR000560   His_Pase_clade-2       

SUPFAM

SSF52540   SSF52540        + More
SSF47473   SSF47473       
SSF53254   SSF53254       

Gene 3D

3.40.50.1240    

CDD

cd00052  EH
cd07061  HP_HAP_like

ProteinModelPortal

A0A194QEQ2   A0A220K8I4   A0A3S2NZX2   E2AZE9   A0A151WJF0   A0A0J7N331   + More
A0A195CQM0   A0A2J7R596   E2C8F3   A0A026WV74   F4WGA5   A0A195B693   A0A158NI61   A0A232EL11   E9IB79   A0A195EGP8   A0A151JXC0   Q16T24   A0A1W4WR69   A0A023ETP5   A0A154P3I4   A0A1J1IJV4   U5EMK8   A0A2A3EAJ6   V9IMV7   A0A088A395   A0A1Q3FC31   B0WNC3   A0A411G820   A0A1Y1N381   A0A0T6AXK7   A0A084W7R4   A0A1Q3FC63   A0A0M9A7H5   K7J964   B4KC47   A0A310SEK6   Q7Q7M8   A0A1Y9GKD8   A0A182VJ75   A0A182LNL6   R4G5H8   Q8T6I0   A0A182Q189   Q8IGN0   B4MBB5   B4NI15   Q299V4   A0A034W1B4   A0A0L7QXR0   R4WJU9   B3M1W0   A0A0L0CSV7   B4QS70   B4HGF8   B3P472   Q8T8W3   B4PPE1   A0A2M4CTJ3   A0A2M3Z4V5   A0A336K5Q6   T1P861   A0A1L8ECI4   A0A1B0CRC7   A0A1I8PMV3   A0A139WP92   A0A1L8ECY2   A0A2M4AEW8   A0A3B0K9Z4   A0A1W4UMX8   A0A1L8DM80   A0A0K8VR18   A0A1S4GM49   E0VWS6   A0A0A1XQJ0   W8C0Q9   A0A0A9YYD3   A0A0P4VH63   D3TMZ1   A0A1A9VS50   A0A1A9ZGE4   A0A0K8TAD0   A0A1A9XDL2   A0A0A9Z0A3   A0A2M4AFA1   A0A0A9W3E3   A0A0P6I8F2   A0A0P5B0F6   A0A0K8SCA0   E9GJ29   N6T8R1   A0A0A9YXZ4   A0A0M4ECQ3   A0A0P5ZNQ1   A0A023FLZ2   V5HPU0   A0A0P6BUH4   A0A023GL46   A0A1E1X9N6   A0A131Y206  

PDB

5MVF     E-value=0,     Score=1884

KEGG

101737204    K12483 EH domain-containing protein 1 | (RefSeq) EH domain-containing protein 3

PATHWAY

04144    Endocytosis - Bombyx mori (domestic silkworm)

GO

GO:0005525   GO:0005509   GO:0005623   GO:0032456   GO:0008587   GO:0006897   GO:0007474   GO:0007291   GO:1990255   GO:0048477   GO:0071212   GO:0042670   GO:0045466   GO:0048052   GO:0005515   GO:0005886   GO:0007155   GO:0000049   GO:0004812   GO:0043039   GO:0042555   GO:0048384  

PANTHER

PTHR11216:SF57  

Length:

532

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00304

Exp number, first 60 AAs:

0.00028

Total prob of N-in:

0.00100

outside

1  -  532

 

 

Pi

245.817492

Theta

19.910007

Tajima's D

1.013765

CLR

0.202743

CSRT

0.674666266686666

Interpretation

Uncertain