Gene

KWMTBOMO03710  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA002739

Annotation

attacin_[Bombyx_mori]

Location

Bomo_Chr6(+):16166563-16167462      View in EpiBrowser

Full name

Attacin       + More
Attacin-E      
Attacin-B      
Defense protein 3      
Attacin-A      

Alternative Name

Nuecin
Immune protein P5

Location in the cell

Extracellular   Reliability : 1.648 Mitochondrial   Reliability : 1.569

CDS

ATGTCCAAGAGTGTAGCGTTGTTGTTGTTGTGCGCGTGCTTGGCGAGCGGTAGACACGTGCCGACACGTGCGCGGAGACAAGCCGGCAGCTTCACAGTGAACTCGGATGGAACCTCCGGGGCCGCCCTGAAGGTCCCTCTCACCGGCAACGACAAGAACGTACTCAGCGCCATCGGGTCCGCCGACTTCAACGACCGCCACAAGCTCAGCGCCGCCTCCGCAGGGCTCGCTCTGGACAATATAAACGGGCACGGGCTGAGCCTGACCGGGACCCGCATTCCCGGCTTCGGGGAGCAGCTCGGCGTCGCAGGCAAGGTCAACTTGTTCCACAATAACAACCACGACCTGAGCGCCAAGGCGTTCGCGATCAGGAACTCGCCCAGCGCCATCCCCAACGCGCCCAACTTCAACACGCTGGGCGGCGGACTGGACTACATGTTCAAACAGAAGGTGGGCGCATCGCTGAGCGCGGCGCACTCTGACGTCATCAACCGGAATGACTACTCGGCCGGCGGTAAGCTGAACCTGTTCCAATCTCCGTCCAGCTCGCTCGACTTCAACGCCGGCTTCAAGAAGTTTGATACGCCTTTTTACAGATCTTCGTGGGAGCCCAATGTAGGATTCTCCTTCTCTAAATTCTTCTAA

Protein

MSKSVALLLLCACLASGRHVPTRARRQAGSFTVNSDGTSGAALKVPLTGNDKNVLSAIGSADFNDRHKLSAASAGLALDNINGHGLSLTGTRIPGFGEQLGVAGKVNLFHNNNHDLSAKAFAIRNSPSAIPNAPNFNTLGGGLDYMFKQKVGASLSAAHSDVINRNDYSAGGKLNLFQSPSSSLDFNAGFKKFDTPFYRSSWEPNVGFSFSKFF

Description

Has antibacterial activity against both Gram-positive and Gram-negative bacteria.

Miscellaneous

There are six forms of attacin that are divided into two groups: acidic (E and F) and basic (A, B, C, and D).

Similarity

Belongs to the attacin/sarcotoxin-2 family.

Keywords

Antibiotic   Antimicrobial   Cleavage on pair of basic residues   Complete proteome   Immunity   Innate immunity   Reference proteome   Secreted   Signal   Direct protein sequencing   Repeat  

Feature

chain  Attacin

Uniprot

H9IZQ4   H9IZR2   Q26431   D2XRA5   Q0VJU9   Q86M98   + More
J9XS98   P01513   Q56G50   Q95YJ3   Q95YJ2   P01512   B2CZ89   J9XUA5   Q5MGE6   Q0Q042   Q0Q039   Q4PKJ0   P50725   A1E9A9   C5MKE0   O96361   A0A0G3DN05   A0A2A4JPN6   A0A2H1WMR6   A0A2W1BU65   Q58HM7   E2DQE1   Q0Q041   A0A2H1WXU6   A0A0G3DJL6   A0A212FKX9   J9XNB4   A0A212FKY7   A0A0L7LN23   A0A3S2NA53   A0A3S2LMN4   A0A437B4Y1   A0A437B552   A0A194PIH0   D8L125   I4DJ70   A0A0N1PI64   A0A437AQV9   A0A212FNR7   A0A0G3DRX6   A0A194PIR5   I4DJH0   B2CZ90   T2C8M9   A0A437B4Y4   A0A2H1X0N7   A0A0L7LMR4   A0A0N1IEV1   A0A0L7LN30   I4DRF7   A0A212FFC0   A0A1I8NXM0   A0A1I8P7U4   B3NRL8   B4QED3   Q95UA1   Q95NP8   B4P4I4   A0A0J9RBV8   B4HRN6   Q95UA0   B4QFX9   P45884   B3MGX7  

Pubmed

19121390    7773256    8607809    12706633    14728663    2001705    + More
16453548    3840100    16453547    12110295    2406140    16023793    16857061    8890742    9818384    25993013    28756777    22118469    26227816    26354079    22651552    24155672    17994087    11606542    17550304    22936249    7742836    10767526    10731132    12537572   

EMBL

BABH01037979    S78369    AF005384    D76418    GU244351    ADB08384.1    + More
AM293325    CAL25130.1    AY232304    AAO74640.1    JX294493    AFS30775.1    X57715    X00869    M34926    AY960680    AAX58607.1    AB059394    BAB69461.1    AB059395    BAB69462.1    X17619    X00787    X62290    M34925    EU557307    ACB45562.1    JX294494    AFS30776.1    AY829840    DQ666488    ABG72692.1    DQ666491    ABG72695.1    DQ072728    AAY82587.1    U46130    EF114292    ABL63641.1    GQ120502    ACR78454.1    AF023277    AAD09288.1    KP056509    AKJ54491.1    NWSH01000918    PCG73544.1    ODYU01009732    SOQ54359.1    KZ150002    PZC75283.1    AY948540    AAX51192.1    GU111531    ADN51980.1    DQ666489    ABG72693.1    ODYU01011847    SOQ57822.1    KP056510    AKJ54492.1    AGBW02007944    OWR54405.1    JX294492    AFS30774.1    OWR54404.1    JTDY01000509    KOB76847.1    RSAL01000157    RVE45569.1    RSAL01002229    RVE40547.1    RVE45566.1    RSAL01000126    RVE45568.1    RVE46563.1    KQ459602    KPI93211.1    FJ438392    ACR82290.1    AK401338    BAM17960.1    KQ460427    KPJ14761.1    RSAL01005472    RVE40007.1    AGBW02004511    OWR55396.1    KP056511    AKJ54493.1    KPI93212.1    AK401438    BAM18060.1    EU557308    ACB45563.1    KF146178    AGV28582.1    RVE45567.1    ODYU01012449    SOQ58756.1    KOB76848.1    KPJ14762.1    JTDY01000537    KOB76749.1    AK405098    BAM20497.1    AGBW02008836    OWR52427.1    CH954179    EDV56170.2    CM000362    EDX06923.1    AY056855    AAL23641.1    AY056857    AY056861    AY056862    AY056863    AY056864    AY056865    AAL23643.1    AAL23646.1    AAL23647.1    AAL23648.1    AAL23649.1    AAL23650.1    CM000158    EDW90623.2    CM002911    KMY93476.1    CH480816    EDW47900.1    AY056856    AAL23642.1    EDX07124.1    KMY93826.1    Z46893    AF220544    AE013599    CH902619    EDV37895.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000037510    UP000283053    UP000053268    + More
UP000053240    UP000095300    UP000008711    UP000000304    UP000002282    UP000001292    UP000000803    UP000007801   

PRIDE

H9IZQ4    H9IZR2    Q26431    D2XRA5    P50725    Q95UA1    + More
Q95NP8    Q95UA0    P45884   

Pfam

PF03768   Attacin_N        + More
PF03769   Attacin_C
PF10793   Gloverin

Interpro

IPR040428   Attacin/Sarcotoxin-2        + More
IPR005520   Attacin_N       
IPR005521   Attacin_C       
IPR019729   Gloverin-like_protein       

ProteinModelPortal

H9IZQ4   H9IZR2   Q26431   D2XRA5   Q0VJU9   Q86M98   + More
J9XS98   P01513   Q56G50   Q95YJ3   Q95YJ2   P01512   B2CZ89   J9XUA5   Q5MGE6   Q0Q042   Q0Q039   Q4PKJ0   P50725   A1E9A9   C5MKE0   O96361   A0A0G3DN05   A0A2A4JPN6   A0A2H1WMR6   A0A2W1BU65   Q58HM7   E2DQE1   Q0Q041   A0A2H1WXU6   A0A0G3DJL6   A0A212FKX9   J9XNB4   A0A212FKY7   A0A0L7LN23   A0A3S2NA53   A0A3S2LMN4   A0A437B4Y1   A0A437B552   A0A194PIH0   D8L125   I4DJ70   A0A0N1PI64   A0A437AQV9   A0A212FNR7   A0A0G3DRX6   A0A194PIR5   I4DJH0   B2CZ90   T2C8M9   A0A437B4Y4   A0A2H1X0N7   A0A0L7LMR4   A0A0N1IEV1   A0A0L7LN30   I4DRF7   A0A212FFC0   A0A1I8NXM0   A0A1I8P7U4   B3NRL8   B4QED3   Q95UA1   Q95NP8   B4P4I4   A0A0J9RBV8   B4HRN6   Q95UA0   B4QFX9   P45884   B3MGX7  

KEGG

101743224    no KO assigned | (RefSeq) attacin-like

GO

GO:0019731   GO:0005615   GO:0045087   GO:0042742   GO:0005576   GO:0050829   GO:0050830   GO:0055093   GO:0006959   GO:0007156   GO:0016020   GO:0005886   GO:0007155   GO:0000049   GO:0004812   GO:0043039   GO:0042555   GO:0048384  

PANTHER

PTHR38333  

Subcellular location

Secreted  

SignalP

Position:   1 - 17,         Likelihood:  0.938825

 

 

Length:

214

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.265550000000001

Exp number, first 60 AAs:

0.26465

Total prob of N-in:

0.02045

outside

1  -  214

 

 

Pi

30.807156

Theta

28.159152

Tajima's D

0.386452

CLR

0.079314

CSRT

0.488575571221439

Interpretation

Uncertain