SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO03626  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA006263
Annotation
PREDICTED:_T-complex_protein_1_subunit_alpha_[Amyelois_transitella]
Full name
T-complex protein 1 subunit alpha      
Alternative Name
CCT-alpha
Chaperonin containing TCP1 subunit 1
Location in the cell
Cytoplasmic   Reliability : 3.79
 

Sequence

CDS
ATGTCGACTATAGCTGCACCTTTGTCTGTAGCAGGGACAAGATCCTGCGGAGACCCAGTGAGAACACAAAATGTAATGGCAGCAGCGGCTATAGCAAACATAGTAAAGAGCTCCCTTGGGCCAGTTGGTCTGGATAAGATGCTGGTTGACGATATTGGGGATGTTACAGTCACTAACGATGGTGCCACAATATTAAAAATGCTGGAAGTGGAGCATCCTGCTGCCAAAGTCTTAGTGGAACTAGCACAGCTACAAGATGAAGAAGTTGGAGATGGTACCACATCTGTAGTCATCATTGCTGCTGAACTACTTAAGAATGCAGATGAACTAGTGAAGACCAAGATCCATCCAACAAGCATTATCTCAGGATACCGTCTCGCCTGTAAAGAAGCAGTCAAGTACATTCAGGATAACCTCACAGTAACAGTAGAGTCACTTGGCAGGCCGTCTCTGATCAACACAGCCAAAACAACCATGTCATCTAAACTAATTGGAGCTGATGCAGATTTCTTCTCGGAGATGGTTGTAGATGCTGCACAGGCAATCAAAACAATGAACCCCAGAGGAAATACTATATACCCTATCAAAGCTATTAACATTCTGAAAGCCCACGGCCGGAGTGCAAGGGAAAGTGTACTTGTCAAAGGCTATGCTCTGAACTGCACTGTAGCATCACAGGCAATGCCGAAGAAGATTCTCAATGCAAAGATCGCCTGCCTTGATTTTTCTCTGCAAAAAACTAAGATGAAATTGGGTGTTCAGGTTCTTGTGACTGATCCAGAAAAATTAGAAGCGATCCGTGCAAGAGAACTGGACATTACCAAAGAACGCTTACAGAAGATTCTCGCTACCGGCGTCAATGTTATTCTTTGCACCGGAGGCATTGATGATCTATGTTTGAAATATTTCGTTGAAGCTGGAGCAATGGGTGTCAGGAGGTGTAAGAAGGCAGATCTAAAAAGGATTGCCAAGGCTACTGGAGCTACTTTTTTGACTTCTTTGACTAATATGGATGGTGAGGAAGTATTTGAAGCTAATATGATTGGTGAAGCCGCTGAAGTGATCCAGGAACAAATCTGTGATGATCAACTTATTTTAATCAAAGGGCCGGCAGCGCGCACGGCCGCGTCGCTTATCCTGCGCGGTCCCACGGACGCGTACTGCGACGAGATGGAGCGGTCCGCGCACGACGCGCTGTGCGCCGTGCGCCGCGTGCTGGAGTCCGGCAAGCTCGTGCCCGGCGGCGGCGCGGTCGAAGCGGCACTCTCCATCTACTTGGAGAACTTTGCAACTACCCTCAGCTCCCGCGAGCAGTTGGCTATTGCAGCGTTTGCGCAGTCTCTCCTCGTGATCCCGAAGACGTTGGCGGTTAACGCGGCGCGGGACGCCACCGACCTCGTCGCCAAGCTACGAGCCTACCACAACTCATCACAAACCAAGGTGGAACACGCAAACCTCAAATGGGTAGGTCTGGATCTAACAGAAGGAACACTCCGGGACAACCTCGCAGCCGGAGTCCTCGAGCCAGCGATATCCAAGATCAAATCGTTGAAATTCGCAACAGAAGCTGCGATTACTATTCTCCGTATTGACGATATGATCAAACTCGACCCCGAACAAAGAGGCAAGAGCTATGAAGACGCTTGCAATGCCGGTGAACTGGACTAA
Protein
MSTIAAPLSVAGTRSCGDPVRTQNVMAAAAIANIVKSSLGPVGLDKMLVDDIGDVTVTNDGATILKMLEVEHPAAKVLVELAQLQDEEVGDGTTSVVIIAAELLKNADELVKTKIHPTSIISGYRLACKEAVKYIQDNLTVTVESLGRPSLINTAKTTMSSKLIGADADFFSEMVVDAAQAIKTMNPRGNTIYPIKAINILKAHGRSARESVLVKGYALNCTVASQAMPKKILNAKIACLDFSLQKTKMKLGVQVLVTDPEKLEAIRARELDITKERLQKILATGVNVILCTGGIDDLCLKYFVEAGAMGVRRCKKADLKRIAKATGATFLTSLTNMDGEEVFEANMIGEAAEVIQEQICDDQLILIKGPAARTAASLILRGPTDAYCDEMERSAHDALCAVRRVLESGKLVPGGGAVEAALSIYLENFATTLSSREQLAIAAFAQSLLVIPKTLAVNAARDATDLVAKLRAYHNSSQTKVEHANLKWVGLDLTEGTLRDNLAAGVLEPAISKIKSLKFATEAAITILRIDDMIKLDPEQRGKSYEDACNAGELD

Summary

Subunit
Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
Similarity
Belongs to the TCP-1 chaperonin family.
Keywords
ATP-binding   Chaperone   Complete proteome   Cytoplasm   Nucleotide-binding   Reference proteome  
Feature
chain  T-complex protein 1 subunit alpha
EMBL
BABH01026063    ODYU01012664    SOQ59095.1    NWSH01003141    PCG66872.1    KZ149893    + More
PZC78925.1    KQ460647    KPJ13170.1    KQ459011    KPJ04341.1    GFDL01012759    JAV22286.1    GEZM01032423    JAV84588.1    GEDC01027930    JAS09368.1    CH477573    EAT38836.1    JXUM01058052    JXUM01058053    GAPW01000783    KQ561984    JAC12815.1    KXJ76987.1    CVRI01000073    CRL07614.1    DS231872    EDS41399.1    KQ971312    EEZ98476.1    AXCN02001566    AXCM01001325    NEVH01013976    PNF28020.1    AAAB01008880    EAA08611.4    APCN01005054    GAMC01002228    JAC04328.1    LJIG01009109    KRT83738.1    GECZ01011030    JAS58739.1    KF621132    AHB33468.1    ATLV01006810    KE524386    KFB35314.1    JRES01001160    KNC24958.1    GAKP01005041    JAC53911.1    AB194475    BAE17115.1    GDHF01001955    JAI50359.1    GBXI01011616    JAD02676.1    GALX01000840    JAB67626.1    CM000070    EAL27853.1    CH479179    EDW24566.1    OUUW01000013    SPP88118.1    GGFM01002931    MBW23682.1    KA647586    AFP62215.1    NNAY01003191    OXU19832.1    GAMD01003021    JAA98569.1    GANO01001490    JAB58381.1    GGFJ01003898    MBW53039.1    GGFK01003652    MBW36973.1    ADMH02000944    ETN64609.1    CH902617    EDV44182.1    BT127458    AEE62420.1    KZ288451    PBC25575.1    CH964272    EDW85045.1    CH940656    EDW58354.1    CH954182    EDV54136.1    GFDF01004044    JAV10040.1    CM000364    EDX13936.1    AE014297    AAN13906.1    CH480815    EDW43198.1    M21159    AY118416    CM000160    EDW98012.1    CH933806    EDW16889.1    CH916373    EDV94656.1    LJIG01016411    KRT80681.1    JXJN01007683    KK852785    KDR16554.1    GDAI01000404    JAI17199.1    JXUM01042913    KQ561343    KXJ78896.1    UFQS01000609    UFQT01000609    SSX05331.1    SSX25692.1    ADTU01017356    KK107145    EZA57501.1    GAIX01004472    JAA88088.1    AGBW02010943    OWR47487.1    CCAG010014864    EZ422351    ADD18627.1    DS235088    EEB11539.1    GECU01027893    JAS79813.1    PNF28021.1    GL732550    EFX79881.1    GDIP01131700    GDIP01092293    GDIP01071546    GDIP01043251    GDIQ01077549    GDIQ01054014    LRGB01002190    JAM11422.1    JAN17188.1    KZS08616.1    GDIP01219432    JAJ03970.1    GDIP01122385    JAL81329.1    CP012526    ALC47235.1    GDIP01123844    JAL79870.1    GDIQ01046322    JAN48415.1   
Pfam
PF00118   Cpn60_TCP1
Interpro
IPR027409   GroEL-like_apical_dom_sf        + More
IPR027413   GROEL-like_equatorial_sf       
IPR002194   Chaperonin_TCP-1_CS       
IPR017998   Chaperone_TCP-1       
IPR027410   TCP-1-like_intermed_sf       
IPR002423   Cpn60/TCP-1       
IPR012715   Chap_CCT_alpha       
SUPFAM
SSF48592   SSF48592        + More
SSF54849   SSF54849       
SSF52029   SSF52029       
Gene 3D
PDB
4B2T     E-value=0,     Score=1971

Ontologies

Topology

Subcellular location
Cytoplasm  
Length:
555
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.073
Exp number, first 60 AAs:
0.01102
Total prob of N-in:
0.00106
outside
1  -  555
 
 

Population Genetic Test Statistics

Pi
18.537183
Theta
16.015021
Tajima's D
0.585042
CLR
0.165525
CSRT
0.553372331383431
Interpretation
Uncertain
Peptides ×
Source Sequence Identity Evalue
31250652 EICETIVSGIQPLQNFGLK 100.00 7e-14
28467696 IIGAAPK 95.24 8e-06
28556443 TQNVMAAAAIANIVK 100.00 4e-04
26822097 ESVIVK 100.00 0.003
26280517 GPNIDANVTK 100.00 0.003
25044914 GPSFIQIIDEIPSINRK 100.00 0.003
27102218 YFVEAGAMGVR 100.00 0.003
28467696 GPSNPSQEVPWDIIDR 100.00 0.003
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