Gene

KWMTBOMO03623  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA006265

Annotation

PREDICTED:_thioredoxin_domain-containing_protein_5_[Bombyx_mori]

Location

Bomo_Chr6(-):13709710-13714957      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.554 Extracellular   Reliability : 1.091 PlasmaMembrane   Reliability : 1.123

CDS

ATGAAGATATTACCATATCTATTTGTATTTCCGTATCTTGTAGCTCCTGAACAGAGTTCTGTTTACGAATACAATCCCAGTAATTTCAAATTCCAGATCGAAGAAATGGATGGAAACTTTATTATGTTTTACGCGCCATGGTGTAGACATTGCACAGAATTTTATCCGATATGGTCAGAATTGGCAGAGCTGGTTAATACCAAGGACTCCAAATTTGCCATTGCCCAAGTTGACTGCACAGTGCATGCTAAGCTTTGTCATGAAAATGAAATAACAGGTTATCCAACATTATTTTATTTCCACAAAAATACATTTACACCAGTTGAATACAAAGGAACAAGGGACTTACCATCATTGACATTGTTTCTGAGCGAAGCCTTCTCTGTCAAAACAGAGGGCAAACAATCAAAACAACCAAATGAAGTTAAAACATACAGCGGCATGTCCTATCTGAATGACCTGAATATTGAGAAGTTTGTGTCAAAAGGACAGCATTTCATCATGTTTTTTGTACCTTGGTGTCGTGCATCTCAGAGGATGGCACCGATTTGGGCAGACTTAGCAGTACATTACGCTCACAACAACTACATAAAAATTGGAAAAGTTAATTGTATGGATAATGAGATAACATGCGAAAATTTTGAAGTCAAACAGTACCCCTATTTACTCTGGATTGTTAATGGAAAAATTATGGGTGCTTCGAATGGGGAAAACTTAGACGATTTGAAAGCATTTGTTGAAAAAATGTTGCTTTCTGAAAATCACGATCCAGAGAAATTTCTAAGAAAAAAGAAAGCACTTCCTGTGGCCAGGATATCTGAGGAGACATTCGAAACTTTTCTGCAAAATGACTTAGTTTTTATTAATTATTTTGCGCCATGGTGCGCACATTGTATGCAGTTAAGCCCATTATGGATTAAATTAGGGGAAAAGTTCCAAAACGAGACAAGAGTATTGATAGCAGATGTTGACTGTGTGCAGAGTAAACCTATTTGTGAAACAGAAAAGATTAATGGACTACCCACATTAATATTGTACAGACATAAGAAAATAGTAAGTGTAGAACATGGTGGTAGACCTCTTGATAGTCTGATTGGACTCATCACAGAGCATTTACAAGATTCAGCCAGTACAGATCCAGAAGACAAGACAAATGAGGACATATTTTTGTCAAAAGCCAAAGACGAATTGTAA

Protein

MKILPYLFVFPYLVAPEQSSVYEYNPSNFKFQIEEMDGNFIMFYAPWCRHCTEFYPIWSELAELVNTKDSKFAIAQVDCTVHAKLCHENEITGYPTLFYFHKNTFTPVEYKGTRDLPSLTLFLSEAFSVKTEGKQSKQPNEVKTYSGMSYLNDLNIEKFVSKGQHFIMFFVPWCRASQRMAPIWADLAVHYAHNNYIKIGKVNCMDNEITCENFEVKQYPYLLWIVNGKIMGASNGENLDDLKAFVEKMLLSENHDPEKFLRKKKALPVARISEETFETFLQNDLVFINYFAPWCAHCMQLSPLWIKLGEKFQNETRVLIADVDCVQSKPICETEKINGLPTLILYRHKKIVSVEHGGRPLDSLIGLITEHLQDSASTDPEDKTNEDIFLSKAKDEL

Similarity

Belongs to the protein disulfide isomerase family.

Uniprot

H9J9S2   A0A2A4J559   A0A2W1BV46   A0A194QFL9   A0A194R5S9   A0A0L7LQY7   + More
A0A212ER45   A0A224XI07   V5GI69   T1HXQ3   A0A0K8SP98   A0A0A9XS29   A0A1W4WW63   D6WD23   A0A088AID6   E2B7N7   A0A0C9RKX2   A0A1B0CZI9   A0A2R7W1M4   A0A195FWA3   A0A1Y1K2X5   A0A151WV88   F4WNH5   F5B4Q2   A0A0P4WIM3   A0A293MWJ0   B7PHA0   A0A1S3DB21   E9FY51   A0A1L8DU05   A0A220XIQ9   U5ER38   A0A0P4ZYN5   A0A158NXZ4   A0A1B6DFB0   A0A0P5BIV9   A0A067QSV0   A0A0P5BPG9   A0A0P5WTL7   A0A0P5ZTP5   A0A0P5KFW1   A0A0P6CVG8   A0A0P6E4V3   A0A0P5ZLB6   A0A0P5TR08   A0A0P5CTX2   A0A0P5XH58   A0A0P5BPG7   A0A0T6B8U2   A0A1Q3F9P0   A0A2A3EJY6   A0A0P5B5Q6   A0A0P4WMZ7   Q17I04   A0A1S4F1W0   A0A164M4U4   A0A0P5SYM4   A0A0P5FJD1   A0A023ESN4   A0A2J7QRB2   A0A0P5DBJ1   A0A2R5LFZ4   A0A1L8EID4   B3MQD1   A0A0L0BRP8   A0A1I8PHM3   Q1HR90   U4UU64   A0A1L8EEK6   N6TSU7   A0A1A9VRC5   A0A0P5ZUX1   A0A0P5CYL0   A0A1A9XDU9   A0A1B0B8G6   A0A023F8J0   R4G5U7   A0A023EQD7   A0A2T7PG55   A0A0L7QVY2   A0A1B0A064   A0A0M4EUS3   J3JWJ1   E0VDX9   A0A0P5VHN2   A0A0P5VI97   V4AG03   A0A195ECZ0   A0A1W4VZU0   B3NU99   A0A1A9WCI7   A0A3B0K196   B4NDP8   Q29JA8   A0A151IM81   A0A1I8NGE4   B4R365   A0A1J1ICW5   A0A1J1I965  

Pubmed

19121390    28756777    26354079    26227816    22118469    25401762    + More
18362917    19820115    20798317    28004739    21719571    21292972    21347285    24845553    17510324    24945155    17994087    26108605    17204158    23537049    25474469    22516182    20566863    23254933    15632085    25315136   

EMBL

BABH01026061    BABH01026062    BABH01026063    NWSH01003141    PCG66876.1    KZ149893    + More
PZC78928.1    KQ459011    KPJ04338.1    KQ460647    KPJ13173.1    JTDY01000294    KOB77845.1    AGBW02013152    OWR43931.1    GFTR01005742    JAW10684.1    GALX01004717    JAB63749.1    ACPB03021026    GBRD01010781    JAG55043.1    GBHO01020850    JAG22754.1    KQ971311    EEZ99095.1    GL446193    EFN88315.1    GBYB01008830    JAG78597.1    AJVK01020820    KK854227    PTY13338.1    KQ981215    KYN44597.1    GEZM01098817    JAV53736.1    KQ982706    KYQ51850.1    GL888237    EGI64168.1    HQ630061    AEE36485.1    GDRN01070603    GDRN01070602    JAI63841.1    GFWV01018787    MAA43515.1    ABJB010253034    ABJB010429163    ABJB010654407    ABJB010897971    ABJB011140338    DS711754    EEC05972.1    GL732527    EFX87477.1    GFDF01004152    JAV09932.1    MF278684    ASL04990.1    GANO01002981    JAB56890.1    GDIP01206344    JAJ17058.1    ADTU01002818    GEDC01012917    JAS24381.1    GDIP01189243    JAJ34159.1    KK853582    KDR06511.1    GDIP01181741    JAJ41661.1    GDIP01082653    JAM21062.1    GDIP01051119    GDIP01039964    JAM63751.1    GDIQ01210412    JAK41313.1    GDIQ01086808    JAN07929.1    GDIP01252576    GDIQ01068923    JAI70825.1    JAN25814.1    GDIP01147750    GDIP01045722    JAM57993.1    GDIP01158899    GDIP01140754    GDIQ01068922    JAL62960.1    JAN25815.1    GDIP01166589    JAJ56813.1    GDIP01084507    JAM19208.1    GDIP01181740    JAJ41662.1    LJIG01009148    KRT83659.1    GFDL01010741    JAV24304.1    KZ288222    PBC32037.1    GDIP01189246    JAJ34156.1    GDIP01254580    JAI68821.1    CH477244    EAT46272.1    LRGB01003089    KZS04728.1    GDIP01133601    JAL70113.1    GDIQ01253760    JAJ97964.1    GAPW01001802    JAC11796.1    NEVH01011914    PNF31129.1    GDIP01163749    JAJ59653.1    GGLE01004308    MBY08434.1    GFDG01000385    JAV18414.1    CH902621    EDV44557.1    JRES01001467    KNC22673.1    DQ440204    ABF18237.1    KI209717    KI210120    KI210134    ERL96078.1    ERL96160.1    ERL96167.1    GFDG01001678    JAV17121.1    APGK01053332    KB741223    ENN72350.1    GDIP01038713    JAM65002.1    GDIP01163748    JAJ59654.1    JXJN01009934    GBBI01001052    JAC17660.1    GAHY01000210    JAA77300.1    GAPW01001801    JAC11797.1    PZQS01000004    PVD32417.1    KQ414721    KOC62772.1    CP012528    ALC48885.1    BT127609    AEE62571.1    DS235088    EEB11585.1    GDIP01099800    JAM03915.1    GDIP01099801    JAM03914.1    KB201864    ESO94095.1    KQ979074    KYN22709.1    CH954180    EDV46014.1    OUUW01000003    SPP78791.1    CH964239    EDW81870.1    CH379063    EAL32393.1    KQ977063    KYN06001.1    CM000366    EDX17667.1    CVRI01000044    CRK96814.1    CRK96813.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000037510    UP000007151    + More
UP000015103    UP000192223    UP000007266    UP000005203    UP000008237    UP000092462    UP000078541    UP000075809    UP000007755    UP000001555    UP000079169    UP000000305    UP000005205    UP000027135    UP000242457    UP000008820    UP000076858    UP000235965    UP000007801    UP000037069    UP000095300    UP000030742    UP000019118    UP000078200    UP000092443    UP000092460    UP000245119    UP000053825    UP000092445    UP000092553    UP000009046    UP000030746    UP000078492    UP000192221    UP000008711    UP000091820    UP000268350    UP000007798    UP000001819    UP000078542    UP000095301    UP000000304    UP000183832   

PRIDE

H9J9S2    A0A088AID6    B7PHA0   

Pfam

PF00085   Thioredoxin        + More
PF00782   DSPc
PF00383   dCMP_cyt_deam_1
PF08766   DEK_C

Interpro

IPR036249   Thioredoxin-like_sf        + More
IPR013766   Thioredoxin_domain       
IPR017937   Thioredoxin_CS       
IPR005788   Disulphide_isomerase       
IPR020103   PsdUridine_synth_cat_dom_sf       
IPR016193   Cytidine_deaminase-like       
IPR002125   CMP_dCMP_dom       
IPR029021   Prot-tyrosine_phosphatase-like       
IPR016130   Tyr_Pase_AS       
IPR000387   TYR_PHOSPHATASE_dom       
IPR000340   Dual-sp_phosphatase_cat-dom       
IPR014876   DEK_C       
IPR020422   TYR_PHOSPHATASE_DUAL_dom       

SUPFAM

SSF52833   SSF52833        + More
SSF55120   SSF55120       
SSF53927   SSF53927       
SSF52799   SSF52799       

Gene 3D

3.90.190.10    

CDD

cd00127  DSPc

ProteinModelPortal

H9J9S2   A0A2A4J559   A0A2W1BV46   A0A194QFL9   A0A194R5S9   A0A0L7LQY7   + More
A0A212ER45   A0A224XI07   V5GI69   T1HXQ3   A0A0K8SP98   A0A0A9XS29   A0A1W4WW63   D6WD23   A0A088AID6   E2B7N7   A0A0C9RKX2   A0A1B0CZI9   A0A2R7W1M4   A0A195FWA3   A0A1Y1K2X5   A0A151WV88   F4WNH5   F5B4Q2   A0A0P4WIM3   A0A293MWJ0   B7PHA0   A0A1S3DB21   E9FY51   A0A1L8DU05   A0A220XIQ9   U5ER38   A0A0P4ZYN5   A0A158NXZ4   A0A1B6DFB0   A0A0P5BIV9   A0A067QSV0   A0A0P5BPG9   A0A0P5WTL7   A0A0P5ZTP5   A0A0P5KFW1   A0A0P6CVG8   A0A0P6E4V3   A0A0P5ZLB6   A0A0P5TR08   A0A0P5CTX2   A0A0P5XH58   A0A0P5BPG7   A0A0T6B8U2   A0A1Q3F9P0   A0A2A3EJY6   A0A0P5B5Q6   A0A0P4WMZ7   Q17I04   A0A1S4F1W0   A0A164M4U4   A0A0P5SYM4   A0A0P5FJD1   A0A023ESN4   A0A2J7QRB2   A0A0P5DBJ1   A0A2R5LFZ4   A0A1L8EID4   B3MQD1   A0A0L0BRP8   A0A1I8PHM3   Q1HR90   U4UU64   A0A1L8EEK6   N6TSU7   A0A1A9VRC5   A0A0P5ZUX1   A0A0P5CYL0   A0A1A9XDU9   A0A1B0B8G6   A0A023F8J0   R4G5U7   A0A023EQD7   A0A2T7PG55   A0A0L7QVY2   A0A1B0A064   A0A0M4EUS3   J3JWJ1   E0VDX9   A0A0P5VHN2   A0A0P5VI97   V4AG03   A0A195ECZ0   A0A1W4VZU0   B3NU99   A0A1A9WCI7   A0A3B0K196   B4NDP8   Q29JA8   A0A151IM81   A0A1I8NGE4   B4R365   A0A1J1ICW5   A0A1J1I965  

PDB

2DIZ     E-value=1.57524e-17,     Score=219

KEGG

101735315    K13984 thioredoxin domain-containing protein 5 | (RefSeq) thioredoxin domain-containing protein 5

PATHWAY

04141    Protein processing in endoplasmic reticulum - Bombyx mori (domestic silkworm)

GO

GO:0005623   GO:0045454   GO:0016853   GO:0043277   GO:0003756   GO:0016021   GO:0001522   GO:0003723   GO:0009982   GO:2000427   GO:0005783   GO:0008138   GO:0004725   GO:0008270   GO:0046872   GO:0022857   GO:0005215   GO:0051103   GO:0005524   GO:0042555   GO:0048384  

SignalP

Position:   1 - 16,         Likelihood:  0.864212

 

 

Length:

397

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.03082

Exp number, first 60 AAs:

0.00362

Total prob of N-in:

0.00117

outside

1  -  397

 

 

Pi

18.373807

Theta

23.357917

Tajima's D

-0.521207

CLR

10.305241

CSRT

0.234888255587221

Interpretation

Uncertain