Silkworm Genome Informatics Database

Gene

KWMTBOMO03604

Pre Gene Modal

BGIBMGA006322

Annotation

PREDICTED:_soluble_guanylate_cyclase_89Db-like_[Bombyx_mori]

Location

Bomo_Chr6(+):13368211-13397142 View in EpiBrowser

Full name

Angiotensin-converting enzyme

Location in the cell

Mitochondrial Reliability : 1.78

CDS

ATGTACGGTTGGCTGTTGGAAAGCGTACAACATTTCATTGTGGAGGAATGTGGGGAAGAAATATGGGAAACGATTCTAAGGGAGGCAGGTGCCAGAAACACAGTCTTCAGTGCGACACAGCAATACCCAGACGCCCTGATGCTCCGACTAGCCAGCGCTTTAGCTCGTCTCCTCTCAAAAGACCCCAACAGCCCTGTACCGTCCCGGCCAGCGAGTCCAGTACCAAAGAAACCATCTTTCAAATCCAAGCCCAGCTGGAGAAGCGCATCAGTCCACGCAGACAATAGACCACAGACCTTCAAATGTCCCTTCACAGCCACAAACGTATTGACAGCTGTCACTAAGAAAGAAATTAATGCTTACACGTCTACTGAAGAGATTCGACCAATGACAATGTCAACTGACCGCATAAATATGGAAAAGGGAATAGAAGTGGTCAGAAAGGAGTTGCAGAGGCGCAGTTTGGGGATCAAATTAGAAGCGGTGCATGCAGAGAAGAGTAAGGAAACCCCTGAAGAATCTATTCCAGAATGTGAGCAAGCGGAGAGTCAGAACGCCGCCTCGGAACCCACATCCCCTGAGCACGAGAATATGAAAAACTCCATGTCCAAGCCAACAAGGAAGACTAGTTGTACCGTAGCATTGGATGTATACCGGCGGCGAGGGTCAGGAGCTCCGGGAAGGCAAAGACTGAACAGCATCAGCCTCATTTCGTGCGAGAAACTAAACGCCATGAAAGAGAAATTTGCCACACCGGAAAAGGTGATGCACTTCTTCGGCAGGTGCTTTGTGAAATTCTTCAGCAATTACGGCTACGACACTATGATACGTGCGACCGGTCGATACTTCTGCACATTCCTGCAGTCCGTGGACAACATCCATCAGCGTATGCGGTACACTTTTCCGAGGATGCGGTCTCCGAGCATGCAGCTCACGAGGGCTCACAGGCACGGAGCTGAACTCGTATACAGCAGTGGAAGGACCGGCTTTACGCATTACCTGATGGGCCAGCTCTACGAGATAGCCGAGGACATCTTCTCATTGAAGTTGAAAGTTTCCATCATGAAAGAGAGCATGGAGGGAACATACTATAATGCGGTTCTGAGATTGGAGTTCGACAATAGTGATTACGTACAATCGTTGATGTTCCGCAAGAACATAGCGTGTCCTCTACCATCGGTGCCGGCTTCGCTACTGCTGCAATTGTTTCCGTTTGGAGTACTGCTTGACCGAAGAATGAAAATCTTAATGGCCGGCGAAAAATTGGTAGCTGCTTGGGGCGGACCGTATAATCGTATTGAAAAATCGTCAATCGTCGAAGTTCTACGCCTGAGGAAACCAAAAGTTTCGTTTACTTGGGATAAGGTGGTCTGTATGCAGACAATGATCTTCGAACTGGAGTTGGTGCGTTGGCGTGCGAAGTCCACGAGTGAGGCGAGACGAGGGTCTCAGGGTGCCCGTTCCATATTATTAAGGGGACCCATTTATCTACTCGAAGAAATTGACGCCCTCATCTTCTTATGCAGTCCCATCTTCAATGATCTAGAGGAAATCCGGCAAGCAGGTCTATACGTCGCCGATATGAACGGACATGGACTCTCTAAGGAGATGCTCCTAAACGGTTGGCAGCATCTCTCCAGACTAGAACTACTGTTCGAGAAAGCGGAGACCCGATGTTCGTCTTTGGAGAAATCCTGTAGACTACTGGACCAGTGGAAGAAGAGAGGCGATCAGCTGTTATACTCCATGATACCGAAGGGAATTGCTGATCATTTGAGAGCAGGACGAGATCCGATGGCTGCTTGTCAAGCGTTCGAATCTGTGACGATAATATTCTGCGGAGTCCAGGTAGCAGAGGCGGGGACTCGTGCCGACGTCATGCAGACCGTCGCTTATATTAACGATGTGTATTCGAGGATCGACCGGCTCCTTGATACTCATCGAGTTTATAAGTAA

Protein

MYGWLLESVQHFIVEECGEEIWETILREAGARNTVFSATQQYPDALMLRLASALARLLSKDPNSPVPSRPASPVPKKPSFKSKPSWRSASVHADNRPQTFKCPFTATNVLTAVTKKEINAYTSTEEIRPMTMSTDRINMEKGIEVVRKELQRRSLGIKLEAVHAEKSKETPEESIPECEQAESQNAASEPTSPEHENMKNSMSKPTRKTSCTVALDVYRRRGSGAPGRQRLNSISLISCEKLNAMKEKFATPEKVMHFFGRCFVKFFSNYGYDTMIRATGRYFCTFLQSVDNIHQRMRYTFPRMRSPSMQLTRAHRHGAELVYSSGRTGFTHYLMGQLYEIAEDIFSLKLKVSIMKESMEGTYYNAVLRLEFDNSDYVQSLMFRKNIACPLPSVPASLLLQLFPFGVLLDRRMKILMAGEKLVAAWGGPYNRIEKSSIVEVLRLRKPKVSFTWDKVVCMQTMIFELELVRWRAKSTSEARRGSQGARSILLRGPIYLLEEIDALIFLCSPIFNDLEEIRQAGLYVADMNGHGLSKEMLLNGWQHLSRLELLFEKAETRCSSLEKSCRLLDQWKKRGDQLLYSMIPKGIADHLRAGRDPMAACQAFESVTIIFCGVQVAEAGTRADVMQTVAYINDVYSRIDRLLDTHRVYK

Cofactor

Zn(2+)

Similarity

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Belongs to the peptidase M2 family.

Uniprot

A0A2A4JT61 A0A194QG06 A0A194R7H4 A0A212F4L0 A0A067QN87 A0A182QSP8 + More
A0A182N9U0 A0A182HAF3 Q16G04 Q16KE1 W5JJI0 A0A084WT83 A0A336KLM2 A0A0P5NIZ5 A0A164QJM2 A0A0P6C694 A0A0P6I5V8

EC Number

3.4.-.-

Pubmed

26354079 22118469 24845553 26483478 17510324 20920257 + More
23761445 24438588

EMBL

NWSH01000685 PCG74804.1 KQ459249 KPJ02381.1 KQ460647 KPJ13190.1 + More
AGBW02010349 OWR48660.1 KK853216 KDR09774.1 AXCN02001200 JXUM01031343 KQ560918 KXJ80357.1 CH478352 EAT33174.1 CH477963 EAT34765.1 ADMH02001350 ETN62919.1 ATLV01026865 ATLV01026866 KE525420 KFB53427.1 UFQS01000244 UFQT01000244 SSX01940.1 SSX22317.1 GDIQ01141663 JAL10063.1 LRGB01002384 KZS07815.1 GDIP01008416 JAM95299.1 GDIQ01009113 JAN85624.1

Proteomes

UP000218220 UP000053268 UP000053240 UP000007151 UP000027135 UP000075886 + More
UP000075884 UP000069940 UP000249989 UP000008820 UP000000673 UP000030765 UP000076858

Pfam

PF07701   HNOBA        + More
PF00211   Guanylate_cyc
PF07700   HNOB
PF01401   Peptidase_M2
PF07690   MFS_1

Interpro

IPR038158   H-NOX_domain_sf        + More
IPR011645   HNOB_dom_associated
IPR029787   Nucleotide_cyclase
IPR001054   A/G_cyclase
IPR011644   Heme_NO-bd
IPR024096   NO_sig/Golgi_transp_ligand-bd
IPR018297   A/G_cyclase_CS
IPR020846   MFS_dom
IPR036259   MFS_trans_sf
IPR011701   MFS
IPR001548   Peptidase_M2

SUPFAM

SSF55073   SSF55073        + More
SSF111126   SSF111126
SSF103473   SSF103473

Gene 3D

3.30.70.1230 3.90.1520.10

CDD

cd06461 M2_ACE
cd06174 MFS

ProteinModelPortal

A0A2A4JT61 A0A194QG06 A0A194R7H4 A0A212F4L0 A0A067QN87 A0A182QSP8 + More
A0A182N9U0 A0A182HAF3 Q16G04 Q16KE1 W5JJI0 A0A084WT83 A0A336KLM2 A0A0P5NIZ5 A0A164QJM2 A0A0P6C694 A0A0P6I5V8

PDB

5MNW E-value=4.07072e-10, Score=157

KEGG

101746281 K01769 guanylate cyclase, other [EC:4.6.1.2] | (RefSeq) soluble guanylate cyclase 89Db-like

GO

GO:0004383 GO:0020037 GO:0035556 GO:0000166 GO:0055085 GO:0016021 GO:0008237 GO:0004180 GO:0046872 GO:0008241 GO:0006182 GO:0009190 GO:0016849 GO:0051103 GO:0005524 GO:0008270 GO:0042555 GO:0048384

PANTHER

PTHR10514

Length:

651

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.62479

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00477

outside

1 - 651

Pi

31.191095

Theta

36.598402

Tajima's D

-0.519817

CLR

1.681201

CSRT

0.23958802059897

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics