Gene

KWMTBOMO03545

Pre Gene Modal

BGIBMGA006234

Annotation

PREDICTED:_angiotensin-converting_enzyme-like_[Bombyx_mori]

Location

Bomo_Chr6(-):11507954-11524384      View in EpiBrowser

Full name

Angiotensin-converting enzyme      

Location in the cell

Cytoplasmic   Reliability : 1.679 Nuclear   Reliability : 1.387

CDS

ATGGGGACGTTCACTCTCCCCGTTTTCTTCTTACTACTTGCGTCGTGTCCTACTCTTCGAGGAACGTCTTCAAGTGACGACGATCGAAGATGGCTGGTTTCTATGATAGACCTGGTCGAAATGGACTACGTAGATCATTGCGAGCAAAGATCCAGTGCCGCTTGGAGTGAGCTCACTGGCAGCAGCAAAGGACTACATCTAAAGTTGGAACGAGACAAATCGTTTGGCCTATTTTCTCAACATCAAACAACGGAAGTGAAGAACACCCTTACCGCTCACGCTTTAGCCCCGGACGACAATATCCTGAGACGCAAAGTTAAGCTTCTGTTGCAACCTGGCGACACGCTTATGGAAAGTGAACAGTGGATTCGGCTCGTAACATTCGGGGACACGGCTCTGCACAAGATTCGCACAGCTACGAACTACGATTGTGGCACCAGTACAAACTGCACTTTACGAGAGTTACACTATAACTTGGCAAGGCAGCAAGATGAGGAGACACTGCGTCGTATGAAGATATCTTGGGAGAAGAACCTACCAAATATGACTGATTACCTTGAGCATATTCTGCCGTTGCTAAGAAACGCTTCGAAACAGAACAACTACAACACTCTTGAAGACTATTGGGACGAGCTTGTTGAATACGAAGGTGCAACTCTCAAAGCCAGGGAATTATGGGGCAAAATTAATCCTTTGTACACAAAACTACATAAGTACGTGGCCTTGAAGCTTAAGGGATTGGACGCCATTGGGAAGCCCTTGCCTGTTCATTTATTTAGGTCGCTCACAGGAGAAGATTGGTCTAACTTAATAGAGAGCCTATTACCAAAACACGCGGGAATTTATCAGAAAGTTCACGCAAATCTACAATTGAAGGACCTCGGAGGGTTGAAAGCGTTCAAGCAAGCAGCTAAACTAATTACAGCTCTGAACTTTGGCGAAATGAATCCTGAAGTTTTCTCTGAATCAATATTTAATAGCACCTGTCCAACAACATTGGTGGACTGGTGTCAGCCTAATAAAATGAGGGCCGTCACCTGCAAGGATGTTAGTTTAGCAAATTACATAGAAGCCCATGAAGCCGTAATGAAGATAAAGTATAAGCAAATTATCAATTTGCACAGTAACAATACTTACATTCTGAGAGAAGCCCCGCGATATTCCGCCATCTATGAAGCTATACCAGGATTTACGTCCCTCCTGTCCCTAAATCCCCATGCTTTACACAGAGCCGGTCTGTTCCCGATCGAAATATTTAATTACAATCAAAATTTTCATCGGTTAGTCTTGCAACTGATCACGGCGCTTAGGGATCTGCCAAAATTAAATTTCTATTTGGCTGCAGATGAATGGAGACTGAACGTCCTCATGGGATCAATTCCATATGCAAAAATTCCCCGAAGCTGGAGTGATTTCCGCTCCAATTTTTCTCTTATCGAATCATCTGATTCGGACTTCCTCGGAGATCCCTATATGGTTTTCAATAAACCATTTATCGGAAAATTTCTCGGAATCATTCTAAAGTATCAAATATACTTATCTTTTGCTGACGAACTTATGTCCGATGATGACGATCTTATTCAATACGTTTCCCAACACAATGACCGATTAGTTGACATAATGATGCAAGGATACAGTACAAGCTGGCCTGAAATGATAAGTGATGTGTTGGGGAAACGAGAAAATAGTCTGGAATATACAGGAATAACAGACTATTATAGACTCTTAGATGAATATCTAGACAACCAACTGGAACCTTCCGCTGATAACGAAGAACCATATGATTACTTGGAAGTTGAAGACTTCGATGTGGAGCCTGAAGTTAATGAAATACCCACGATACCAGAAACGACTGAATTACCTCAAAAAGTGGAAACACATGAAGATTTAAGTGAAAACGTAATAAACACGGGTGATGACATTAACTCAAAATTCGGTATTGAAACTTCTACTGTAGGCGTTTTGGAGATCAAAAACCCCGTTGTAGCTAAGGACCAAAACAAGGATGTAGCTCCTAAAGAAGCTTCCTACAATTTGTATTGGTGGATAGGAATCGGTGTAGCTATAGCTGTAGTTGTGATATTAATAGCTATTATTGCGAGGAAGCGTCAGAGCCACAGAAAGCAGCTGGAGAGGCAACGTAGAACGACCGCCTGA

Protein

MGTFTLPVFFLLLASCPTLRGTSSSDDDRRWLVSMIDLVEMDYVDHCEQRSSAAWSELTGSSKGLHLKLERDKSFGLFSQHQTTEVKNTLTAHALAPDDNILRRKVKLLLQPGDTLMESEQWIRLVTFGDTALHKIRTATNYDCGTSTNCTLRELHYNLARQQDEETLRRMKISWEKNLPNMTDYLEHILPLLRNASKQNNYNTLEDYWDELVEYEGATLKARELWGKINPLYTKLHKYVALKLKGLDAIGKPLPVHLFRSLTGEDWSNLIESLLPKHAGIYQKVHANLQLKDLGGLKAFKQAAKLITALNFGEMNPEVFSESIFNSTCPTTLVDWCQPNKMRAVTCKDVSLANYIEAHEAVMKIKYKQIINLHSNNTYILREAPRYSAIYEAIPGFTSLLSLNPHALHRAGLFPIEIFNYNQNFHRLVLQLITALRDLPKLNFYLAADEWRLNVLMGSIPYAKIPRSWSDFRSNFSLIESSDSDFLGDPYMVFNKPFIGKFLGIILKYQIYLSFADELMSDDDDLIQYVSQHNDRLVDIMMQGYSTSWPEMISDVLGKRENSLEYTGITDYYRLLDEYLDNQLEPSADNEEPYDYLEVEDFDVEPEVNEIPTIPETTELPQKVETHEDLSENVINTGDDINSKFGIETSTVGVLEIKNPVVAKDQNKDVAPKEASYNLYWWIGIGVAIAVVVILIAIIARKRQSHRKQLERQRRTTA

Cofactor

Zn(2+)

Similarity

Belongs to the peptidase M2 family.

Feature

chain  Angiotensin-converting enzyme

Uniprot

A0A2A4K6X2   A0A2H1WRX9   A0A1E1WU53   A0A1E1W9B7   A0A212FJ71   A0A194QVR2   + More
A0A194QBQ0   A0A067R7H1   E2BSZ8   E2AQI4   A0A158NYF9   A0A026WDG4   D2A565   V5G3L2   A0A154PCH7   V5GKK7   F4WT47   K7JH20   A0A195AYH8   A0A2A3EBR2   A0A195F5X1   A0A0L7RGM3   A0A088ANF6   A0A232EWV7   A0A1B6KA09   A0A0T6B9N2   A0A1B6GNU4   A0A0N0BBH5   A0A2S2PXK3   A0A2K9Y420   A0A182R3U4   A0A2H8TCU4   A0A2M4BDM0   Q7Q1J9   A0A2M4BCK2   A0A2M4BCM7   A0A0K8T5T2   A0A2M3ZE07   A0A2M3Z1D4   A0A023F3X6   A0A1J1IC50   K7IXA0   A0A1Y1NHL6   A0A1B6DUB7   A0A084WU13   A0A150RLJ5   A0A3Q0IXC2   A0A0C9RBF0   A0A395JP68   A0A0P5NKM2   A0A150R9S0   A0A0P5FWE4   A0A154PMJ3   A0A2S2PBL3   A0A0P5YQN8   A0A0P5W4G4   A0A026VXF5   A0A3L8DDW7   A0A0N7ZQD9   A0A0P5CWD0   A0A158P0W6   A0A151WW54  

EC Number

3.4.-.-

Pubmed

22118469    26354079    24845553    20798317    21347285    24508170    + More
18362917    19820115    21719571    20075255    28648823    12364791    26823975    25474469    28004739    24438588    30249741   

EMBL

NWSH01000069    PCG79987.1    ODYU01010594    SOQ55813.1    GDQN01000475    JAT90579.1    + More
GDQN01007490    JAT83564.1    AGBW02008316    OWR53760.1    KQ461181    KPJ07651.1    KQ459249    KPJ02415.1    KK852651    KDR19443.1    GL450313    EFN81186.1    GL441773    EFN64293.1    ADTU01003791    KK107295    EZA53089.1    KQ971361    EFA05125.1    GALX01003856    JAB64610.1    KQ434864    KZC08968.1    GALX01003857    JAB64609.1    GL888331    EGI62660.1    KQ976701    KYM77246.1    KZ288292    PBC29175.1    KQ981768    KYN35985.1    KQ414596    KOC69979.1    NNAY01001817    OXU22830.1    GEBQ01031706    GEBQ01013511    JAT08271.1    JAT26466.1    LJIG01002990    KRT83950.1    GECZ01014580    GECZ01005674    JAS55189.1    JAS64095.1    KQ436008    KOX67604.1    GGMS01000887    MBY70090.1    KY612467    AUW14597.1    GFXV01000118    MBW11923.1    GGFJ01001966    MBW51107.1    AAAB01008980    EAA14517.3    GGFJ01001638    MBW50779.1    GGFJ01001639    MBW50780.1    GBRD01005048    GBRD01005045    GDHC01019599    GDHC01011567    JAG60776.1    JAP99029.1    JAQ07062.1    GGFM01005960    MBW26711.1    GGFM01001578    MBW22329.1    GBBI01002586    JAC16126.1    CVRI01000044    CRK96558.1    AAZX01008641    AAZX01009269    GEZM01002421    JAV97269.1    GEDC01008045    JAS29253.1    ATLV01026973    ATLV01026974    ATLV01026975    ATLV01026976    ATLV01026977    ATLV01026978    ATLV01026979    ATLV01026980    ATLV01026981    ATLV01026982    KE525421    KFB53707.1    JEMC01003508    JEMD01001356    KYF80826.1    KYF97647.1    GBYB01013809    JAG83576.1    QNRT01000001    RBP53297.1    GDIQ01140929    JAL10797.1    JEMB01002955    KYF76982.1    GDIQ01254826    JAJ96898.1    KQ434980    KZC13072.1    GGMR01013687    MBY26306.1    GDIP01055046    JAM48669.1    GDIP01091235    LRGB01001253    JAM12480.1    KZS13268.1    KK107622    EZA48457.1    QOIP01000009    RLU18657.1    GDIP01222825    JAJ00577.1    GDIP01164551    JAJ58851.1    ADTU01005878    ADTU01005879    ADTU01005880    ADTU01005881    ADTU01005882    KQ982691    KYQ52124.1   

Proteomes

UP000218220    UP000007151    UP000053240    UP000053268    UP000027135    UP000008237    + More
UP000000311    UP000005205    UP000053097    UP000007266    UP000076502    UP000007755    UP000002358    UP000078540    UP000242457    UP000078541    UP000053825    UP000005203    UP000215335    UP000053105    UP000075900    UP000007062    UP000183832    UP000030765    UP000075518    UP000079169    UP000253083    UP000076858    UP000279307    UP000075809   

Pfam

PF01401   Peptidase_M2        + More
PF08190   PIH1

Interpro

IPR001548   Peptidase_M2        + More
IPR012981   PIH1_N       
IPR008979   Galactose-bd-like_sf       
IPR011989   ARM-like       

SUPFAM

SSF49785   SSF49785       

Gene 3D

1.25.10.10    

CDD

cd06461  M2_ACE

ProteinModelPortal

A0A2A4K6X2   A0A2H1WRX9   A0A1E1WU53   A0A1E1W9B7   A0A212FJ71   A0A194QVR2   + More
A0A194QBQ0   A0A067R7H1   E2BSZ8   E2AQI4   A0A158NYF9   A0A026WDG4   D2A565   V5G3L2   A0A154PCH7   V5GKK7   F4WT47   K7JH20   A0A195AYH8   A0A2A3EBR2   A0A195F5X1   A0A0L7RGM3   A0A088ANF6   A0A232EWV7   A0A1B6KA09   A0A0T6B9N2   A0A1B6GNU4   A0A0N0BBH5   A0A2S2PXK3   A0A2K9Y420   A0A182R3U4   A0A2H8TCU4   A0A2M4BDM0   Q7Q1J9   A0A2M4BCK2   A0A2M4BCM7   A0A0K8T5T2   A0A2M3ZE07   A0A2M3Z1D4   A0A023F3X6   A0A1J1IC50   K7IXA0   A0A1Y1NHL6   A0A1B6DUB7   A0A084WU13   A0A150RLJ5   A0A3Q0IXC2   A0A0C9RBF0   A0A395JP68   A0A0P5NKM2   A0A150R9S0   A0A0P5FWE4   A0A154PMJ3   A0A2S2PBL3   A0A0P5YQN8   A0A0P5W4G4   A0A026VXF5   A0A3L8DDW7   A0A0N7ZQD9   A0A0P5CWD0   A0A158P0W6   A0A151WW54  

PDB

6H5W     E-value=4.60857e-17,     Score=218

KEGG

101742492    K01283 peptidyl-dipeptidase A [EC:3.4.15.1] | (RefSeq) angiotensin-converting enzyme-like

GO

GO:0008237   GO:0016021   GO:0008241   GO:0004180   GO:0046872   GO:0005886   GO:0008238   GO:0005615   GO:0008239   GO:0016020   GO:0006508   GO:0051103   GO:0005524   GO:0008270   GO:0042555   GO:0048384  

PANTHER

PTHR10514  

SignalP

Position:   1 - 21,         Likelihood:  0.973825

 

 

Length:

718

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

22.08615

Exp number, first 60 AAs:

0.02124

Total prob of N-in:

0.00110

outside

1  -  677

TMhelix

678  -  700

inside

701  -  718

 

 

Pi

264.00916

Theta

179.010688

Tajima's D

1.484527

CLR

0.207667

CSRT

0.782660866956652

Interpretation

Uncertain