Gene

KWMTBOMO03522  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA006246

Annotation

PREDICTED:_NADP-dependent_malic_enzyme_[Bombyx_mori]

Location

Bomo_Chr6(+):10418965-10435883      View in EpiBrowser

Full name

Malic enzyme      

Location in the cell

Mitochondrial   Reliability : 1.299

CDS

ATGGAGGCCTGTGTACAGAGATACGGACAGAACACTCTGCTCCAATTTGAGGATTTCGCCCTTCCGAATGCCGGTCGGCTCCTGAAGAAATACCGCAATAAATACTGCACGTTCAACGACGACATCCAAGGTACGGCCAGCGTTGCCGTCGCCGGTCTGATGGCGGCCGTCAGGGTCACGAGGAGGAAGCTCAGTGAGAACATTTACCTTTTCCTCGGTGCTGGATCTGCAGCGAACGGCATCGCGAACTTGACTGTGGCCGCCATGATGGCGGACGGACTCTCCGAGAGGCAGGCCCGCGAGAGAGTGTACATGTTCGACGTCGACGGACTATTGTCCACTCGACGTGAAGGAGGGGTTCCGGAGCACGCCAAGGCCTTCGGGAAGGATATCGAACCGGAGAAAGACTTCGAGGCCTGCGTTGCCAAGATCAAGCCTAGCTGTCTTATTGGTTGTTCAACGGTGGGCGGCGCTTTCACGCCCAATGTATTGAAGCAAATGGCGATGAACACCGAGCGACCCGTCATATTCGCACTCTCGAATCCGACCAGTAAAGCTGAGTGCACAGCCCAAGACGCCTACGACCATACGGAAGGTCGTTGCATATTCGCGTCCGGCTCCCCGTTCCCGCCGGTGATGTACAGCGGCCGGGAGTACCGCCCGGGACAGGGCAACAACGCCTACATCTTCCCCGGTGTGGCGCTCGGCGTCATCGCCACGGCCACGCATCACATCTCCGAGAATATGTTCCTGACGGCGGCCAGGACTTTGGCGAACTACGTAAGCGAGTCGGATCTATCCATCGGTCGCATTTATCCGTCGCTGGCTGAAGTGAAAGAAGTGTCCGTCGCTATCGCCATCGAAGTCGCTAAGACCGCATACGACGAAGGTCTTGCCTCAGTGTATCCAGAGCCTCGCGATCTACCGAAGCACGTACAAAACCAAATGTACAGCTATTATTACGAATCTGCAATGCCGGTGACCTGGGATTGGAAGCCCGAGGAGAAGTTCAACGTTAGACCCATCCAACCTGTACCGAAGAACATTTAA

Protein

MEACVQRYGQNTLLQFEDFALPNAGRLLKKYRNKYCTFNDDIQGTASVAVAGLMAAVRVTRRKLSENIYLFLGAGSAANGIANLTVAAMMADGLSERQARERVYMFDVDGLLSTRREGGVPEHAKAFGKDIEPEKDFEACVAKIKPSCLIGCSTVGGAFTPNVLKQMAMNTERPVIFALSNPTSKAECTAQDAYDHTEGRCIFASGSPFPPVMYSGREYRPGQGNNAYIFPGVALGVIATATHHISENMFLTAARTLANYVSESDLSIGRIYPSLAEVKEVSVAIAIEVAKTAYDEGLASVYPEPRDLPKHVQNQMYSYYYESAMPVTWDWKPEEKFNVRPIQPVPKNI

Similarity

Belongs to the malic enzymes family.

Uniprot

H9J9Q3   A0A194QVQ3   A0A212F922   A0A2H1V9X6   A0A2A4JIT3   A0A194QBR2   + More
A0A2W1BWB1   A0A194QQ65   A0A194QAH0   A0A182GYQ8   A0A182H086   A0A023EXF3   A0A1S4EXR8   Q17M99   A0A0K8WJK7   B0WQC9   A0A2M4ABQ9   W5JPA9   A0A2M4ABS9   A0A2M4BHA3   A0A182RYM9   A0A1B6C7V3   A0A2M4BHC5   A0A182W1I7   A0A182XJ28   A0A182V0I8   A0A182I7T1   A0A1Q3FI86   A0A0K8WI45   A0A0K8UER4   A0A182TL51   A0A2M3Z470   A0A182R0A2   A0A2M3Z419   W8BCJ7   A0A182K1D7   W8ASH1   A0A182FPU6   A0A182YGM6   A0A182LYI4   A0A0A1WP91   A0A0A1X9J1   Q7QB64   A0A182L7C6   F5HL44   T1PDU2   T1PDX1   A0A1I8NSM9   A0A2H1V9T4   A0A182N5S8   A0A1B6DG24   A0A1B6JHS1   A0A182IQ03   A0A1B6FNU9   A0A224XNH8   A0A0P4VPB6   A0A023F4G0   U5EUA8   A0A0L0BYF3   A0A0C9R9Z4   U4UQ11   B3P850   A0A1W4UH31   A0A1W4UIU7   T1I5N5   A0A0R1E5P7   A0A0V0GBL2   A0A0P8XU46   B4PRU5   E1JIZ5   E1JIZ4   B3MT32   A0A0M5J924   A0A1A9YSV7   B4IC50   A0A034V722   Q9VB69   A0A1A9ZZ14   A0A1B0FEH5   A0A0Q9WG72   A0A0Q9WYS2   B4KAX8   A0A0K8TU30   B4LXG6   D6WC30   A0A1A9VFY1   A0A182P1Q3   B4JU20   A0A3B0JE23   A0A3B0KAI4   A0A3B0K3M4   A0A1A9W7B7   A0A0J7KN64   A0A2J7Q043   V9IAE8   V9I857   A0A2W1B8P7   A0A0A9YR05   A0A195D5H8   A0A0Q9WT09  

Pubmed

19121390    26354079    22118469    28756777    26483478    24945155    + More
17510324    20920257    23761445    24495485    25244985    25830018    12364791    14747013    17210077    20966253    25315136    27129103    25474469    26108605    23537049    17994087    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    25348373    26109357    26109356    26369729    18362917    19820115    25401762    26823975   

EMBL

BABH01034014    BABH01034015    BABH01034016    BABH01034017    KQ461181    KPJ07636.1    + More
AGBW02009653    OWR50228.1    ODYU01001426    SOQ37596.1    NWSH01001337    PCG71618.1    KQ459249    KPJ02430.1    KZ149899    PZC78631.1    KPJ07637.1    KPJ02429.1    JXUM01021496    JXUM01021497    JXUM01021498    KQ560602    KXJ81680.1    JXUM01100888    JXUM01100889    KQ564606    KXJ72035.1    GAPW01000494    JAC13104.1    CH477207    EAT47850.1    GDHF01000971    JAI51343.1    DS232039    EDS32800.1    GGFK01004902    MBW38223.1    ADMH02000944    ETN64604.1    GGFK01004916    MBW38237.1    GGFJ01003263    MBW52404.1    GEDC01027794    JAS09504.1    GGFJ01003314    MBW52455.1    APCN01002552    GFDL01007813    JAV27232.1    GDHF01001483    JAI50831.1    GDHF01027238    JAI25076.1    GGFM01002542    MBW23293.1    AXCN02001157    GGFM01002520    MBW23271.1    GAMC01019021    JAB87534.1    GAMC01019022    JAB87533.1    AXCM01000270    GBXI01013791    JAD00501.1    GBXI01006333    JAD07959.1    AAAB01008880    EAA08510.5    EGK97005.1    KA646942    AFP61571.1    KA646941    AFP61570.1    SOQ37595.1    GEDC01012664    JAS24634.1    GECU01008999    JAS98707.1    GECZ01017897    JAS51872.1    GFTR01006845    JAW09581.1    GDKW01003589    JAI53006.1    GBBI01002297    JAC16415.1    GANO01001567    JAB58304.1    JRES01001160    KNC25050.1    GBYB01009772    JAG79539.1    KB632397    ERL94598.1    CH954182    EDV53454.1    ACPB03014452    CM000160    KRK04335.1    GECL01000725    JAP05399.1    CH902623    KPU72841.1    EDW98538.1    AE014297    ACZ95043.1    ACZ95044.1    EDV30422.1    CP012526    ALC46036.1    CH480828    EDW45208.1    GAKP01020653    JAC38299.1    AY051465    AAF56674.1    AAK92889.1    CCAG010001986    CH940650    KRF83517.1    CH933806    KRG01135.1    EDW14656.1    GDAI01000138    JAI17465.1    EDW67844.1    KQ971310    EEZ99125.1    CH916374    EDV91599.1    OUUW01000005    SPP80577.1    SPP80578.1    SPP80579.1    LBMM01005231    KMQ91684.1    NEVH01020327    PNF21946.1    JR036673    AEY57309.1    JR036672    AEY57308.1    KZ150227    PZC72042.1    GBHO01011634    GBHO01009599    GDHC01004108    JAG31970.1    JAG34005.1    JAQ14521.1    KQ976870    KYN07694.1    CH964232    KRF99390.1   

Proteomes

UP000005204    UP000053240    UP000007151    UP000218220    UP000053268    UP000069940    + More
UP000249989    UP000008820    UP000002320    UP000000673    UP000075900    UP000075920    UP000076407    UP000075903    UP000075840    UP000075902    UP000075886    UP000075881    UP000069272    UP000076408    UP000075883    UP000007062    UP000075882    UP000095301    UP000095300    UP000075884    UP000075880    UP000037069    UP000030742    UP000008711    UP000192221    UP000015103    UP000002282    UP000007801    UP000000803    UP000092553    UP000092443    UP000001292    UP000092445    UP000092444    UP000008792    UP000009192    UP000007266    UP000078200    UP000075885    UP000001070    UP000268350    UP000091820    UP000036403    UP000235965    UP000078542    UP000007798   

PRIDE

H9J9Q3    E1JIZ5    E1JIZ4    Q9VB69   

Pfam

PF03949   Malic_M        + More
PF00390   malic
PF00431   CUB

Interpro

IPR037062   Malic_N_dom_sf        + More
IPR001891   Malic_OxRdtase       
IPR012302   Malic_NAD-bd       
IPR015884   Malic_enzyme_CS       
IPR012301   Malic_N_dom       
IPR036291   NAD(P)-bd_dom_sf       
IPR035914   Sperma_CUB_dom_sf       
IPR000859   CUB_dom       

SUPFAM

SSF51735   SSF51735        + More
SSF49854   SSF49854       

Gene 3D

3.40.50.10380     2.60.120.290    

CDD

cd00041  CUB

ProteinModelPortal

H9J9Q3   A0A194QVQ3   A0A212F922   A0A2H1V9X6   A0A2A4JIT3   A0A194QBR2   + More
A0A2W1BWB1   A0A194QQ65   A0A194QAH0   A0A182GYQ8   A0A182H086   A0A023EXF3   A0A1S4EXR8   Q17M99   A0A0K8WJK7   B0WQC9   A0A2M4ABQ9   W5JPA9   A0A2M4ABS9   A0A2M4BHA3   A0A182RYM9   A0A1B6C7V3   A0A2M4BHC5   A0A182W1I7   A0A182XJ28   A0A182V0I8   A0A182I7T1   A0A1Q3FI86   A0A0K8WI45   A0A0K8UER4   A0A182TL51   A0A2M3Z470   A0A182R0A2   A0A2M3Z419   W8BCJ7   A0A182K1D7   W8ASH1   A0A182FPU6   A0A182YGM6   A0A182LYI4   A0A0A1WP91   A0A0A1X9J1   Q7QB64   A0A182L7C6   F5HL44   T1PDU2   T1PDX1   A0A1I8NSM9   A0A2H1V9T4   A0A182N5S8   A0A1B6DG24   A0A1B6JHS1   A0A182IQ03   A0A1B6FNU9   A0A224XNH8   A0A0P4VPB6   A0A023F4G0   U5EUA8   A0A0L0BYF3   A0A0C9R9Z4   U4UQ11   B3P850   A0A1W4UH31   A0A1W4UIU7   T1I5N5   A0A0R1E5P7   A0A0V0GBL2   A0A0P8XU46   B4PRU5   E1JIZ5   E1JIZ4   B3MT32   A0A0M5J924   A0A1A9YSV7   B4IC50   A0A034V722   Q9VB69   A0A1A9ZZ14   A0A1B0FEH5   A0A0Q9WG72   A0A0Q9WYS2   B4KAX8   A0A0K8TU30   B4LXG6   D6WC30   A0A1A9VFY1   A0A182P1Q3   B4JU20   A0A3B0JE23   A0A3B0KAI4   A0A3B0K3M4   A0A1A9W7B7   A0A0J7KN64   A0A2J7Q043   V9IAE8   V9I857   A0A2W1B8P7   A0A0A9YR05   A0A195D5H8   A0A0Q9WT09  

PDB

1O0S     E-value=1.40776e-100,     Score=935

KEGG

101740919    K00029 malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] | (RefSeq) NADP-depe

PATHWAY

00620    Pyruvate metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01200    Carbon metabolism - Bombyx mori (domestic silkworm)

GO

GO:0004471   GO:0046872   GO:0051287   GO:0016021   GO:0005739   GO:0006090   GO:0004470   GO:0006108   GO:0004473   GO:0042593   GO:0004352   GO:0000287   GO:0003723   GO:0006270   GO:0042555   GO:0048384   GO:0055114  

Length:

349

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

24.22431

Exp number, first 60 AAs:

0.70531

Total prob of N-in:

0.94437

inside

1  -  67

TMhelix

68  -  90

outside

91  -  349

 

 

Pi

199.659644

Theta

175.473868

Tajima's D

1.19624

CLR

0.909081

CSRT

0.710114494275286

Interpretation

Uncertain