Gene

KWMTBOMO03521  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA006246

Annotation

PREDICTED:_NADP-dependent_malic_enzyme_[Bombyx_mori]

Location

Bomo_Chr6(+):10403415-10415728      View in EpiBrowser

Full name

Malic enzyme      

Location in the cell

Mitochondrial   Reliability : 1.339

CDS

ATGTTTTCCAGTGTGTCCAGATCGTTATTATGTTGCACAAACGCAATAGGTCCAAACAGGGCCCTGGCGTACATCCTAACAAAGAACTCGATCCTCGAACCTTCCTCGATACAATGTCGGGATTACCACGAAGTAACCGGCAATATCATTTGCCCGAATGTTGTCCGAGGCATCGACCACCTTAGAGATCCTCGCCTTAATAAAGGTCTCGCGTTTACTTTAGAAGAACGTCAGGCTCTCGGCATTCACGGTCTTTTGGCGGCCAAATTCAAAAGTCAAGAAGAACAGCTGGACATTTGCAGGATATCAGTGGACAGATACGAGGACAATCTGAACAAATATCTCTACCTCGTCGAGTTACAGGATCGAAACGAGAAACTGTTCTTTAGACTTCTAGCCGAGAACGTCGAGAAGTATTTACCGATAGTGTACACTCCGACCGTTGGTCTGGCCTGTCAGAGGTTCGGCCTCATATACCGAAGGCCGAGAGGTCTCTTCGTGACTATCAACGACAAAGGCCACGTGTTTAACATCATAAAAAATTGGCCAGAACCTGATGTCCGAGCGATCGTTTTCACCGATGGCGAGAGAATATTGGGCTTGGGTGATCTCGGAGCGTACGGTATGGGGATTCCAGTGGGAAAGCTGTCGCTTTACACAGCTCTGGCTGGGATTAAGCCACACCAATGCTTACCGATTACGCTGGACGTCGGAACGGACAATCAGGTAAAACTTGAAACCATGGCCTAA

Protein

MFSSVSRSLLCCTNAIGPNRALAYILTKNSILEPSSIQCRDYHEVTGNIICPNVVRGIDHLRDPRLNKGLAFTLEERQALGIHGLLAAKFKSQEEQLDICRISVDRYEDNLNKYLYLVELQDRNEKLFFRLLAENVEKYLPIVYTPTVGLACQRFGLIYRRPRGLFVTINDKGHVFNIIKNWPEPDVRAIVFTDGERILGLGDLGAYGMGIPVGKLSLYTALAGIKPHQCLPITLDVGTDNQVKLETMA

Similarity

Belongs to the malic enzymes family.
Belongs to the peptidase C19 family.

Uniprot

H9J9Q3   A0A2W1C0I7   A0A194QBR2   A0A2A4JIT3   A0A2H1V9X6   A0A194QVQ3   + More
A0A212F922   A0A182SMD5   A0A2J7Q031   F5HL44   A0A182XJ28   A0A182V0I8   A0A182I7T1   A0A1B6LG77   A0A182P1Q3   A0A182LYI4   T1E996   A0A067QF27   A0A182TL51   A0A182YGM6   A0A182W1I7   A0A182IQ03   A0A182K1D7   T1PDX1   A0A182RYM9   T1PDU2   A0A182R0A2   A0A182N5S8   A0A2M4ABQ9   A0A2M4ABS9   W5JPA9   A0A182FPU6   A0A1L8E0R1   A0A0K8TU30   A0A2H8TEF4   A0A1S4EXR8   A0A1B6H4G2   Q17M99   A0A2M4BHA3   A0A2M4BHC5   A0A182H086   A0A182GYQ8   A0A2M3Z470   A0A1I8NSM9   A0A2M3Z419   U5EUA8   D6WC30   B0WQC9   A0A336MLA2   A0A1B6DG24   A0A1B6C744   A0A023EXF3   A0A1Q3FI86   A0A1B0DBG6   A0A2P8XVF2   V5GLS7   A0A1B6K6A7   A0A0A9XJW4   J9K007   A0A2H8TYS0   A0A2S2NBL0   A0A0L0BYF3   B4PRU5   T1I5N5   B4IC50   A0A0R1E5P7   A0A2S2Q9I8   A0A023F4G0   A0A0V0GBL2   A0A1W4UIU7   H9J9Q4   A0A2J7Q043   B4KAX8   A0A3B0KAI4   A0A0Q9WYS2   A0A1W4UH31   B4NBE9   A0A0P4VX09   A0A0M5J924   A0A1J1I538   A0A3B0K3M4   A0A0Q9WT09   A0A3B0JE23   B4G2G6   B4JU20   B4LXG6   A0A0P4W311   A0A0Q9WG72   Q9U1J0   A0A1B0B2N3   B3P850   Q9VB69   A0A0P4W9N3   E1JIZ4   E1JIZ5   W8BCJ7   A0A1A9YSV7   A0A1B0FEH5   Q29AC6   A0A1A9ZZ14  

Pubmed

19121390    28756777    26354079    22118469    12364791    14747013    + More
17210077    24845553    25244985    25315136    20920257    23761445    26369729    17510324    26483478    18362917    19820115    24945155    29403074    25401762    26823975    26108605    17994087    17550304    25474469    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    24495485    15632085   

EMBL

BABH01034014    BABH01034015    BABH01034016    BABH01034017    KZ149899    PZC78630.1    + More
KQ459249    KPJ02430.1    NWSH01001337    PCG71618.1    ODYU01001426    SOQ37596.1    KQ461181    KPJ07636.1    AGBW02009653    OWR50228.1    NEVH01020327    PNF21947.1    AAAB01008880    EGK97005.1    APCN01002552    GEBQ01017403    JAT22574.1    AXCM01000270    GAMD01002043    JAA99547.1    KK853743    KDQ87031.1    KA646941    AFP61570.1    KA646942    AFP61571.1    AXCN02001157    GGFK01004902    MBW38223.1    GGFK01004916    MBW38237.1    ADMH02000944    ETN64604.1    GFDF01001848    JAV12236.1    GDAI01000138    JAI17465.1    GFXV01000666    MBW12471.1    GECZ01000197    JAS69572.1    CH477207    EAT47850.1    GGFJ01003263    MBW52404.1    GGFJ01003314    MBW52455.1    JXUM01100888    JXUM01100889    KQ564606    KXJ72035.1    JXUM01021496    JXUM01021497    JXUM01021498    KQ560602    KXJ81680.1    GGFM01002542    MBW23293.1    GGFM01002520    MBW23271.1    GANO01001567    JAB58304.1    KQ971310    EEZ99125.1    DS232039    EDS32800.1    UFQS01001564    UFQT01001564    SSX11469.1    SSX31036.1    GEDC01012664    JAS24634.1    GEDC01028213    JAS09085.1    GAPW01000494    JAC13104.1    GFDL01007813    JAV27232.1    AJVK01029972    PYGN01001288    PSN35985.1    GALX01003447    JAB65019.1    GECU01000718    JAT06989.1    GBHO01023663    GBRD01005565    GDHC01002619    JAG19941.1    JAG60256.1    JAQ16010.1    ABLF02026860    ABLF02026861    GFXV01007658    MBW19463.1    GGMR01001713    MBY14332.1    JRES01001160    KNC25050.1    CM000160    EDW98538.1    ACPB03014452    CH480828    EDW45208.1    KRK04335.1    GGMS01005184    MBY74387.1    GBBI01002297    JAC16415.1    GECL01000725    JAP05399.1    BABH01034018    PNF21946.1    CH933806    EDW14656.1    OUUW01000005    SPP80578.1    KRG01135.1    CH964232    EDW81113.1    GDRN01107055    JAI57478.1    CP012526    ALC46036.1    CVRI01000041    CRK95392.1    SPP80579.1    KRF99390.1    SPP80577.1    CH479179    EDW24011.1    CH916374    EDV91599.1    CH940650    EDW67844.1    GDRN01107058    JAI57477.1    KRF83517.1    AJ251546    CAB64263.1    JXJN01007685    CH954182    EDV53454.1    AE014297    AY051465    AAF56674.1    AAK92889.1    GDRN01107060    JAI57476.1    ACZ95044.1    ACZ95043.1    GAMC01019021    JAB87534.1    CCAG010001986    CM000070    EAL27424.3   

Proteomes

UP000005204    UP000053268    UP000218220    UP000053240    UP000007151    UP000075901    + More
UP000235965    UP000007062    UP000076407    UP000075903    UP000075840    UP000075885    UP000075883    UP000027135    UP000075902    UP000076408    UP000075920    UP000075880    UP000075881    UP000095301    UP000075900    UP000075886    UP000075884    UP000000673    UP000069272    UP000008820    UP000069940    UP000249989    UP000095300    UP000007266    UP000002320    UP000092462    UP000245037    UP000007819    UP000037069    UP000002282    UP000015103    UP000001292    UP000192221    UP000009192    UP000268350    UP000007798    UP000092553    UP000183832    UP000008744    UP000001070    UP000008792    UP000092460    UP000008711    UP000000803    UP000092443    UP000092444    UP000001819    UP000092445   

PRIDE

H9J9Q3    H9J9Q4    Q9U1J0    Q9VB69    E1JIZ4    E1JIZ5    + More

Pfam

PF03949   Malic_M        + More
PF00390   malic
PF00431   CUB
PF00443   UCH
PF01074   Glyco_hydro_38N
PF07748   Glyco_hydro_38C
PF09261   Alpha-mann_mid

Interpro

IPR037062   Malic_N_dom_sf        + More
IPR001891   Malic_OxRdtase       
IPR012302   Malic_NAD-bd       
IPR015884   Malic_enzyme_CS       
IPR012301   Malic_N_dom       
IPR036291   NAD(P)-bd_dom_sf       
IPR035914   Sperma_CUB_dom_sf       
IPR000859   CUB_dom       
IPR016024   ARM-type_fold       
IPR015341   Glyco_hydro_38_cen       
IPR011013   Gal_mutarotase_sf_dom       
IPR000602   Glyco_hydro_38_N       
IPR011330   Glyco_hydro/deAcase_b/a-brl       
IPR028889   USP_dom       
IPR037094   Glyco_hydro_38_cen_sf       
IPR027291   Glyco_hydro_38_N_sf       
IPR028995   Glyco_hydro_57/38_cen_sf       
IPR038765   Papain-like_cys_pep_sf       
IPR018200   USP_CS       
IPR011989   ARM-like       
IPR013780   Glyco_hydro_b       
IPR011682   Glyco_hydro_38_C       
IPR001394   Peptidase_C19_UCH       

SUPFAM

SSF51735   SSF51735        + More
SSF49854   SSF49854       
SSF48371   SSF48371       
SSF74650   SSF74650       
SSF54001   SSF54001       
SSF88713   SSF88713       
SSF88688   SSF88688       

Gene 3D

3.40.50.10380     2.60.120.290     1.20.1270.50     1.25.10.10     2.60.40.1180     3.20.110.10    

CDD

cd00041  CUB

ProteinModelPortal

H9J9Q3   A0A2W1C0I7   A0A194QBR2   A0A2A4JIT3   A0A2H1V9X6   A0A194QVQ3   + More
A0A212F922   A0A182SMD5   A0A2J7Q031   F5HL44   A0A182XJ28   A0A182V0I8   A0A182I7T1   A0A1B6LG77   A0A182P1Q3   A0A182LYI4   T1E996   A0A067QF27   A0A182TL51   A0A182YGM6   A0A182W1I7   A0A182IQ03   A0A182K1D7   T1PDX1   A0A182RYM9   T1PDU2   A0A182R0A2   A0A182N5S8   A0A2M4ABQ9   A0A2M4ABS9   W5JPA9   A0A182FPU6   A0A1L8E0R1   A0A0K8TU30   A0A2H8TEF4   A0A1S4EXR8   A0A1B6H4G2   Q17M99   A0A2M4BHA3   A0A2M4BHC5   A0A182H086   A0A182GYQ8   A0A2M3Z470   A0A1I8NSM9   A0A2M3Z419   U5EUA8   D6WC30   B0WQC9   A0A336MLA2   A0A1B6DG24   A0A1B6C744   A0A023EXF3   A0A1Q3FI86   A0A1B0DBG6   A0A2P8XVF2   V5GLS7   A0A1B6K6A7   A0A0A9XJW4   J9K007   A0A2H8TYS0   A0A2S2NBL0   A0A0L0BYF3   B4PRU5   T1I5N5   B4IC50   A0A0R1E5P7   A0A2S2Q9I8   A0A023F4G0   A0A0V0GBL2   A0A1W4UIU7   H9J9Q4   A0A2J7Q043   B4KAX8   A0A3B0KAI4   A0A0Q9WYS2   A0A1W4UH31   B4NBE9   A0A0P4VX09   A0A0M5J924   A0A1J1I538   A0A3B0K3M4   A0A0Q9WT09   A0A3B0JE23   B4G2G6   B4JU20   B4LXG6   A0A0P4W311   A0A0Q9WG72   Q9U1J0   A0A1B0B2N3   B3P850   Q9VB69   A0A0P4W9N3   E1JIZ4   E1JIZ5   W8BCJ7   A0A1A9YSV7   A0A1B0FEH5   Q29AC6   A0A1A9ZZ14  

PDB

1GQ2     E-value=1.09102e-71,     Score=684

KEGG

101740919    K00029 malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] | (RefSeq) NADP-depe

GO

GO:0004471   GO:0046872   GO:0051287   GO:0016021   GO:0005739   GO:0006090   GO:0004470   GO:0006108   GO:0004473   GO:0042593   GO:0030246   GO:0004559   GO:0006511   GO:0006013   GO:0016579   GO:0036459   GO:0016020   GO:0004352   GO:0000287   GO:0003723   GO:0006270   GO:0042555   GO:0048384   GO:0055114  

Length:

249

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.3319

Exp number, first 60 AAs:

0.00534

Total prob of N-in:

0.01463

outside

1  -  249

 

 

Pi

169.951239

Theta

17.659563

Tajima's D

-0.639652

CLR

1.657539

CSRT

0.212739363031848

Interpretation

Uncertain