Gene

KWMTBOMO03508

Pre Gene Modal

BGIBMGA006540

Annotation

PREDICTED:_solute_carrier_family_46_member_3-like_[Bombyx_mori]

Location

Bomo_Chr6(+):9790350-9803032      View in EpiBrowser

Full name

Angiotensin-converting enzyme      

Location in the cell

PlasmaMembrane   Reliability : 4.94

CDS

ATGGCGATCGATAGCAAAATTTTGGAAAACAACAAGTCTGCAGATAAAATACTTAATAGCAGTGACTTAAATGGAAGTAACATAATTAGTCATAGTATTAAGAACAACAAAAAAGACGGGGAAAATGAACCCAAAGATGATTCCGAGAACTGGGAAGGGCTCGGGATTTTGCAAAAAACAAGGCGTATGATTTCTCTAATTACTGTTGAACCTATTTTGGCTTGTTACGTAATGCCATCGGTATTAGCCGCATTAGCCACACAGAATCTATATTTAGAAAAAGCTTGTCGAGTCAATCTGAGGTTTGAACACCACGTGTGTGATGCACTTACGAGACGAGAAACAACAAATTACACTTTCGAAGAAGAAGCCGTCCAAACATTAGTGGCTTCTGTAACAGGCTGGAAGACTGTTCTACAATCGTTCTTGCCTTGCTTCATATTAATATTCCTCGGAGCGTACAGTGACCGAGTTGGGCAAAGGAAATTTTGCATGCTCCTTCCAATCGTAGGGGAGTTCCTCACAAGCATCGGTCTCATTGTGAACACATACTTCTTCTACGAGTTGCCCGTTGAGGTTGCGGCCGTGACAGAAGCAATATTCCCCGCATTAACCGGAGGCTGGTTCACGATGTTTATGGGGGTGTTTAGTTACATTGGTGACGTTACGACCGAAGAACAACGGACTTTAAGGATAGGAATTGTGAATTTGTTTCATTCCGTGGGAGTACCTGTTGGGGCTGCGCTCAGCGGGATTTTAGTGAGGAAAATCGGATTATACGGTGTGTTTTCCGTTAGTGCTACTTTGTACATACTAAGCTTCATGTATGGATTCTTCAGGATCAAGGAGGTTAAAAAAATTGATCCATCTGTGAAACCACCAAAGAACTGTTGCCATTGGCTTCGTGACTTCTTCGATACAAAGTATGTCAAGGAAACATTGATGGTGGCGTTCAAGAAAGGTCCTAATAATAGAAGACTACGAGTCATAATGCTGGTCGTGGTGCTCTGTGTTATCATTGGACCCATATATGGGGAGATGTCCGTTGTGTACCTTTACACTAGATTCAGGTTTAATTGGAATGAGGTTGACTTCAGTATGTTCTCAACGTACGCTATGTGCACTTCATTACTAGGAACCCTATTTTCGGTCGGAGTCTTCAGCCACGTTATGAAGTTAGACGATGCTATAATTGGAGTGATTTCCTGCACAAGCAAAATACTAGCTGGATTCATGTACGCTTTTGCAACGAAAACATGGCATATTTACTTAGCACCTTTAATTGAAATATTCAACGGAACATCGTTCATAGCTATGAGGTCAATGATCTCGAAGTTGGTGGAAAGGGATGAGTTAGGAAAAGTGAACTCCTTCTTCGGTCTCGCCGAAGCGATGATGCCACTCATTTATGCTCCAATGTATACGACGGTCTACACGGCTACGATTAAATCTTTCCCGGGAGCTTTCTTCTTACTCGGAGGGGGTCTCACGACGCCAGCCGTTCTCATTTTTATGTGGCTCTACCTAGCGAACAAGAAGTACAGTAAACGACAAGACCCCAAGATCGAGAAGCCAATCGAGATTAAAGCCTCCGAAATGTTAGAGAAATCTGGCGTCGACAACAAAGCATACGTGGCGGACAGTGAAGCAAACAAACAGGAAAACATGGAAAAGCAACTAAATGTTCCCGAAACTTCTATAGAAAACGTCAACCAATCTCAAATCGAAATGGGATTTACTGAGAGTATGCTCTGCAACAGAAACATGATATTGGAAACATGA

Protein

MAIDSKILENNKSADKILNSSDLNGSNIISHSIKNNKKDGENEPKDDSENWEGLGILQKTRRMISLITVEPILACYVMPSVLAALATQNLYLEKACRVNLRFEHHVCDALTRRETTNYTFEEEAVQTLVASVTGWKTVLQSFLPCFILIFLGAYSDRVGQRKFCMLLPIVGEFLTSIGLIVNTYFFYELPVEVAAVTEAIFPALTGGWFTMFMGVFSYIGDVTTEEQRTLRIGIVNLFHSVGVPVGAALSGILVRKIGLYGVFSVSATLYILSFMYGFFRIKEVKKIDPSVKPPKNCCHWLRDFFDTKYVKETLMVAFKKGPNNRRLRVIMLVVVLCVIIGPIYGEMSVVYLYTRFRFNWNEVDFSMFSTYAMCTSLLGTLFSVGVFSHVMKLDDAIIGVISCTSKILAGFMYAFATKTWHIYLAPLIEIFNGTSFIAMRSMISKLVERDELGKVNSFFGLAEAMMPLIYAPMYTTVYTATIKSFPGAFFLLGGGLTTPAVLIFMWLYLANKKYSKRQDPKIEKPIEIKASEMLEKSGVDNKAYVADSEANKQENMEKQLNVPETSIENVNQSQIEMGFTESMLCNRNMILET

Cofactor

Zn(2+)

Similarity

Belongs to the peptidase M2 family.
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Uniprot

H9JAJ5   A0A2W1BZD6   A0A2H1W938   A0A194QAI0   A0A212EJ99   A0A1W4WW74   + More
A0A1B6LYH9   A0A182QCE8   A0A2M4BIX1   A0A2M4BIV5   A0A182N9U1   A0A067RJA9   A0A182PQS5   Q16W79   A0A2M4CTY3   Q5TSW5   A0A2C9H8S5   A0A182VHT3   A0A182J2E5   A0A2M4CUE3   A0A2M4CUE7   A0A2M4CSN5   A0A146LMI6   A0A2M3Z330   A0A1B6CY04   A0A2M3Z363   A0A2M4AAV7   A0A1Y1KH29   A0A182MSS2   A0A1J1HPT6   A0A1Q3FLC7   A0A1Q3FLB8   A0A069DVE7   B0WAI1   A0A023F3V3   A0A1I8M3Q0   A0A1I8PUY1   A0A1B6HTG8   J9KB87   D2A535   A0A0A1XR69   W8C3P0   A0A034W601   A0A0K8WKB4   U4URR0   A0A1B0FMN2   A0A0L0C7Q4   A0A026WMI6   A0A1A9WCM0   A0A1W4VHL4   F4WT02   A0A1A9XH14   B4PW63   B4L4F7   A0A1A9VRP7   A0A195AZB4   A0A0M4FAI8   A0A1B0ANC8   B3N1F7   A0A158NYI1   Q9VY22   B4R4V6   B3NUZ2   A0A151ITA2   A0A195F6C4   B4NPQ3   K7J2K2   A0A195CVZ7   A0A151WHP4   B4M2P7   A0A154PAY0   A0A3B0K378   Q29H91   E2A659   B4JJN3   B4GY42   E2BSZ7   Q6NPA2   A0A212FAJ8   A0A1A9ZI85   A0A182RDY9   A0A2H8TM94   E9IUT7   A0A182W3L5   A0A2A3EDD3   A0A0M8ZQJ4   A0A1L8DDP9   A0A088ANF5   A0A084WT83   A0A212FAK5   A0A0L7RGJ1   A0A194REM1   A0A2A4IY18   A0A182F8Z6   A0A194PXP8   A0A194RE89   J9KB15   A0A182K2U1  

EC Number

3.4.-.-

Pubmed

19121390    28756777    26354079    22118469    24845553    17510324    + More
12364791    14747013    17210077    26823975    28004739    26334808    25474469    25315136    18362917    19820115    25830018    24495485    25348373    23537049    26108605    24508170    30249741    21719571    17994087    17550304    21347285    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    20075255    15632085    20798317    21282665    24438588   

EMBL

BABH01009475    BABH01009476    BABH01009477    KZ149899    PZC78617.1    ODYU01007104    + More
SOQ49580.1    KQ459249    KPJ02439.1    AGBW02014503    OWR41557.1    GEBQ01011235    JAT28742.1    AXCN02001200    GGFJ01003792    MBW52933.1    GGFJ01003793    MBW52934.1    KK852651    KDR19441.1    CH477573    EAT38831.1    GGFL01004110    MBW68288.1    AAAB01008898    EAL40562.4    GGFL01004788    MBW68966.1    GGFL01004789    MBW68967.1    GGFL01004111    MBW68289.1    GDHC01010234    JAQ08395.1    GGFM01002176    MBW22927.1    GEDC01018946    GEDC01008979    JAS18352.1    JAS28319.1    GGFM01002194    MBW22945.1    GGFK01004578    MBW37899.1    GEZM01088643    GEZM01088642    JAV58047.1    AXCM01000458    CVRI01000006    CRK88225.1    GFDL01006731    JAV28314.1    GFDL01006678    JAV28367.1    GBGD01001034    JAC87855.1    DS231872    EDS41404.1    GBBI01002626    JAC16086.1    GECU01029729    JAS77977.1    ABLF02035671    KQ971361    EFA05308.1    GBXI01016992    GBXI01013508    GBXI01006853    GBXI01003332    GBXI01000927    JAC97299.1    JAD00784.1    JAD07439.1    JAD10960.1    JAD13365.1    GAMC01005989    JAC00567.1    GAKP01009377    JAC49575.1    GDHF01032155    GDHF01019937    GDHF01013697    GDHF01000723    JAI20159.1    JAI32377.1    JAI38617.1    JAI51591.1    KB632410    ERL95208.1    CCAG010001068    JRES01000902    KNC27439.1    KK107151    QOIP01000003    EZA57287.1    RLU24717.1    GL888331    EGI62615.1    CM000162    EDX01694.1    KRK06299.1    CH933810    EDW07435.1    KQ976701    KYM77299.1    CP012528    ALC49420.1    JXJN01000793    CH902654    EDV33596.1    ADTU01003883    AE014298    BT133123    AAF48383.1    AEY64291.1    CM000366    EDX17913.1    CH954180    EDV47090.1    KQ981029    KYN10190.1    KQ981768    KYN35936.1    CH964291    EDW86493.1    KQ977220    KYN04851.1    KQ983114    KYQ47337.1    CH940651    EDW65951.1    KQ434864    KZC08967.1    OUUW01000015    SPP88717.1    CH379064    EAL31867.2    GL437108    EFN71118.1    CH916370    EDV99785.1    CH479196    EDW27669.1    GL450313    EFN81185.1    BT011024    AAR30184.1    AGBW02009461    OWR50762.1    GFXV01003482    MBW15287.1    GL766050    EFZ15659.1    KZ288292    PBC29176.1    KQ436008    KOX67603.1    GFDF01009508    JAV04576.1    ATLV01026865    ATLV01026866    KE525420    KFB53427.1    OWR50760.1    KQ414596    KOC69980.1    KQ460323    KPJ15909.1    NWSH01004603    PCG64857.1    KQ459586    KPI98097.1    KPJ15907.1    ABLF02027891    ABLF02027892   

Proteomes

UP000005204    UP000053268    UP000007151    UP000192223    UP000075886    UP000075884    + More
UP000027135    UP000075885    UP000008820    UP000007062    UP000076407    UP000075903    UP000075880    UP000075883    UP000183832    UP000002320    UP000095301    UP000095300    UP000007819    UP000007266    UP000030742    UP000092444    UP000037069    UP000053097    UP000279307    UP000091820    UP000192221    UP000007755    UP000092443    UP000002282    UP000009192    UP000078200    UP000078540    UP000092553    UP000092460    UP000007801    UP000005205    UP000000803    UP000000304    UP000008711    UP000078492    UP000078541    UP000007798    UP000002358    UP000078542    UP000075809    UP000008792    UP000076502    UP000268350    UP000001819    UP000000311    UP000001070    UP000008744    UP000008237    UP000092445    UP000075900    UP000075920    UP000242457    UP000053105    UP000005203    UP000030765    UP000053825    UP000053240    UP000218220    UP000069272    UP000075881   

PRIDE

H9JAJ5    Q9VY22    Q6NPA2   

Pfam

PF07690   MFS_1        + More
PF01401   Peptidase_M2
PF07701   HNOBA
PF00211   Guanylate_cyc
PF07700   HNOB

Interpro

IPR020846   MFS_dom        + More
IPR011701   MFS       
IPR036259   MFS_trans_sf       
IPR001548   Peptidase_M2       
IPR018297   A/G_cyclase_CS       
IPR038158   H-NOX_domain_sf       
IPR024096   NO_sig/Golgi_transp_ligand-bd       
IPR011645   HNOB_dom_associated       
IPR029787   Nucleotide_cyclase       
IPR001054   A/G_cyclase       
IPR011644   Heme_NO-bd       

SUPFAM

SSF103473   SSF103473        + More
SSF55073   SSF55073       
SSF111126   SSF111126       

Gene 3D

3.30.70.1230     3.90.1520.10    

CDD

cd06174  MFS
cd06461  M2_ACE

ProteinModelPortal

H9JAJ5   A0A2W1BZD6   A0A2H1W938   A0A194QAI0   A0A212EJ99   A0A1W4WW74   + More
A0A1B6LYH9   A0A182QCE8   A0A2M4BIX1   A0A2M4BIV5   A0A182N9U1   A0A067RJA9   A0A182PQS5   Q16W79   A0A2M4CTY3   Q5TSW5   A0A2C9H8S5   A0A182VHT3   A0A182J2E5   A0A2M4CUE3   A0A2M4CUE7   A0A2M4CSN5   A0A146LMI6   A0A2M3Z330   A0A1B6CY04   A0A2M3Z363   A0A2M4AAV7   A0A1Y1KH29   A0A182MSS2   A0A1J1HPT6   A0A1Q3FLC7   A0A1Q3FLB8   A0A069DVE7   B0WAI1   A0A023F3V3   A0A1I8M3Q0   A0A1I8PUY1   A0A1B6HTG8   J9KB87   D2A535   A0A0A1XR69   W8C3P0   A0A034W601   A0A0K8WKB4   U4URR0   A0A1B0FMN2   A0A0L0C7Q4   A0A026WMI6   A0A1A9WCM0   A0A1W4VHL4   F4WT02   A0A1A9XH14   B4PW63   B4L4F7   A0A1A9VRP7   A0A195AZB4   A0A0M4FAI8   A0A1B0ANC8   B3N1F7   A0A158NYI1   Q9VY22   B4R4V6   B3NUZ2   A0A151ITA2   A0A195F6C4   B4NPQ3   K7J2K2   A0A195CVZ7   A0A151WHP4   B4M2P7   A0A154PAY0   A0A3B0K378   Q29H91   E2A659   B4JJN3   B4GY42   E2BSZ7   Q6NPA2   A0A212FAJ8   A0A1A9ZI85   A0A182RDY9   A0A2H8TM94   E9IUT7   A0A182W3L5   A0A2A3EDD3   A0A0M8ZQJ4   A0A1L8DDP9   A0A088ANF5   A0A084WT83   A0A212FAK5   A0A0L7RGJ1   A0A194REM1   A0A2A4IY18   A0A182F8Z6   A0A194PXP8   A0A194RE89   J9KB15   A0A182K2U1  

KEGG

101735706    K20840 MFS transporter, PCFT/HCP family, solute carrier family 46, member 3 | (RefSeq) solute carrie

GO

GO:0055085   GO:0016021   GO:0004180   GO:0008237   GO:0008241   GO:0046872   GO:0020037   GO:0000166   GO:0035556   GO:0004383   GO:0003676   GO:0008270   GO:0016020   GO:0004352   GO:0000287   GO:0003723   GO:0006270   GO:0042555   GO:0048384  

PANTHER

PTHR10514  

Length:

593

Number of predicted TMHs:

12

Exp number of AAs in TMHs:

261.57919

Exp number, first 60 AAs:

0.00027

Total prob of N-in:

0.97800

inside

1  -  63

TMhelix

64  -  86

outside

87  -  136

TMhelix

137  -  154

inside

155  -  162

TMhelix

163  -  185

outside

186  -  199

TMhelix

200  -  219

inside

220  -  231

TMhelix

232  -  254

outside

255  -  258

TMhelix

259  -  281

inside

282  -  329

TMhelix

330  -  352

outside

353  -  366

TMhelix

367  -  389

inside

390  -  395

TMhelix

396  -  415

outside

416  -  419

TMhelix

420  -  442

inside

443  -  454

TMhelix

455  -  477

outside

478  -  486

TMhelix

487  -  509

inside

510  -  593

 

 

Pi

218.193463

Theta

205.439465

Tajima's D

0.183235

CLR

0.237641

CSRT

0.418979051047448

Interpretation

Uncertain