Gene

KWMTBOMO03454

Pre Gene Modal

BGIBMGA006519

Annotation

PREDICTED:_LOW_QUALITY_PROTEIN:_peroxidase-like_[Bombyx_mori]

Location

Bomo_Chr6(+):8281453-8310287      View in EpiBrowser

Full name

Peroxidase      

Alternative Name

Chorion peroxidase

Location in the cell

Extracellular   Reliability : 1.766

CDS

ATGGCCACGTCTGCTGTTTGGCTCACGCTGGCGCTGACCGGCGCTATACAGTGTGTGCATATAACTGTAAGGAATCCGCGGCAGATATTTATTCAGCATTCGAATCCCGCTCAGACGCCTCTCCGTATCTCAGGCGCAGGGGCGAGGTTTGTAAAGGTGGCTTCTGTCAATCAACCCGCCGATAGACTTCCAGTTTTCGGCTATGGCTTCCAAGATCCTGTCAAAGTTCCAACACTTCAAATCAAAAGTTTCAGCAATCCACCACCACCGCTTGGGTCAGGAGAGGATCCTGCGACCCAGACCTGTGGACTCTCGCCGCCTTTTTGCACCAAATCGAAATACAGATCCATTGATGGGTCTTGCAATAACTTGCTAAGACCTGTATGGGGAATGCCACAAACGCCATACGGCCGATTGGTCCCTTACAATTATGGTGATGGTGTAAGCGCGTGGCCAATATCACGTTCAGGAAATCCTCTGCCGAATCCTCGTGACATAAGTCTCCGGCTCTTCCCCGATCGGCAGTTGATCGATCCAATATGGAACCTTAACGCTCAGCAGTGGGGTCAAATTATAACTCACGATATGTCACTGACCGCCGGCATTGCGCAGAGCCATGCTGATAGGATTACGTGCTGCGATAATAATGGTCTTCTCGCATTGGATGCTACAACCAACCCATTCTGCGCTCCTATATTGGTACCACCGAACGATCCTGTACATTCCCCCCAAGGTACTCAATGTATGAACTTTGTGAGGACCACTTCAACTAGGGACAGAGGTTGTACACCTCCGAATGCACCTGCTGAACCGTTAACGACTGTGACTGCTTACATGGATCTTTCTTTGGTCTACGGAAGCAGTGCTGGTCAAGCAAATCCCATTAGAGCAGGAGCTGGTGGAAGATTGCTAACCATTCTGAGGAAGGGTCAAGAATGGCCTCCCCAGGATCCCAATGTCACGTTAACTTGCGAGTCTGCAAAATCACCCAATGAACCTTGTTACTTAGCCGGTGACATCAGAGTGAATCAGAATCCTCAACTGACGGTGCTGCAGATAATTCTTCTTCGCGAACATAACCGCATCGCCGACACGCTTAGTCGACTCAATCCTCATTGGGACGACGAGACCCTGTTCCAGGAAGCAAGACGAATACATATTGCCGAAATACAGCACATCAATTACTACGAATACCTTCCTATTTTCCTTGGTTTCGAAAACATGGTGAAAAACAAGTTAATCTACCCCGGAGCACATGGTTATGTAAACGATTATAATCCAAACGTTGATCCCACGATCTTAGATGAGCACGCTACTGCCGCTTTCAGACATTTCCATACGTTGATCCGAGGTTATTTAAAGTTAATATCGGAACGTCGTGAACTCGTCGGGGCGGTTCGTATGAGCGACTGGTTCAACAGACCCTTGCTATTGGAAATCAACGACTCCTTCAACAACTTGGCAAGAGGCCTTACTGTTCAGGAACAAGGCTTCAGCGATCAATTTTGGGACACGGAAATTACACAGTTCATGTTTAAGTGA

Protein

MATSAVWLTLALTGAIQCVHITVRNPRQIFIQHSNPAQTPLRISGAGARFVKVASVNQPADRLPVFGYGFQDPVKVPTLQIKSFSNPPPPLGSGEDPATQTCGLSPPFCTKSKYRSIDGSCNNLLRPVWGMPQTPYGRLVPYNYGDGVSAWPISRSGNPLPNPRDISLRLFPDRQLIDPIWNLNAQQWGQIITHDMSLTAGIAQSHADRITCCDNNGLLALDATTNPFCAPILVPPNDPVHSPQGTQCMNFVRTTSTRDRGCTPPNAPAEPLTTVTAYMDLSLVYGSSAGQANPIRAGAGGRLLTILRKGQEWPPQDPNVTLTCESAKSPNEPCYLAGDIRVNQNPQLTVLQIILLREHNRIADTLSRLNPHWDDETLFQEARRIHIAEIQHINYYEYLPIFLGFENMVKNKLIYPGAHGYVNDYNPNVDPTILDEHATAAFRHFHTLIRGYLKLISERRELVGAVRMSDWFNRPLLLEINDSFNNLARGLTVQEQGFSDQFWDTEITQFMFK

Description

Involved in the chorion hardening process, through protein cross-linking mediated by the formation of di- and tri-tyrosine bonds.

Catalytic Activity

2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O

Cofactor

heme b

Similarity

Belongs to the peroxidase family. XPO subfamily.

Keywords

Complete proteome   Disulfide bond   Glycoprotein   Heme   Hydrogen peroxide   Iron   Metal-binding   Oxidoreductase   Peroxidase   Reference proteome   Secreted   Signal  

Feature

chain  Peroxidase

Uniprot

H9JAH4   A0A2A4JJ63   A0A346D9R6   A0A194PXJ3   A0A088MG66   A0A2H1W2P7   + More
A0A194PVX4   A0A194RNM9   A0A194RTJ6   A0A194PVR2   A0A194RPW2   A0A1W4WMG7   H9JAH5   Q177U0   Q16E76   D6WCM3   A0A182G7N2   A0A182IZD9   A0A0L7LVA3   A0A182FTE8   O96645   A0A084V9X6   A0A1Y9HDW6   A0A182PRL2   Q7QDZ3   B0WM28   A0A182MPT8   W5JNS3   B0XE84   A0A182WXU8   A0A182TM70   A0A182I5W9   A0A182KV49   A0A1Y9IWB3   A0A182VL61   A0A182Q218   A0A1Y9H2I7   A0A336MK45   A0A182KBY5   A0A336MHC5   A0A2A3EU99   A0A088AE09   A0A1J1J076   A0A0M4F792   B4M5J8   B4KC82   A0A182Y6T5   A0A1A9W584   A0A0Q9WVU0   B4NJ86   A0A310SND6   A0A2H8TD85   A0A146L6F1   A0A232F2X4   A0A1B6F7C3   N6UAQ6   W8C2M9   K7IYZ3   B4JHE0   A0A0L0CRA6   A0A0A9ZAS3   A0A146M0F8   A0A1B6MDD3   X1WIY8   A0A0A1WQI6   T1I7W3   A0A1I8NQ77   A0A0L7R2K3   A0A0B4KHM9   E1JIN0   Q01603   A0A1W4VTT3   B5DWL8   A0A1I8NQ80   B4G4K4   A0A3B0JQG5   T1PI65   B4QWD4   A0A1B0FFQ7   B3DMS3   B3M2B4   B3P3J1   A0A034WQE0   A0A034WLG7   I1T1H0   B4PM93   A0A154PJR6   A0A0K8VYA7   A0A194PWT3   A0A1A9Y5Z1   A0A0N0BI50   A0A067RJX3   A0A3L8DTW7   E2BCE2   A0A1B0CR56   A0A2J7RAM0   A0A0C9QVC3   A0A2P8XQD7  

EC Number

1.11.1.7

Pubmed

19121390    26354079    25191834    17510324    18362917    19820115    + More
26483478    26227816    11222958    24438588    12364791    20920257    23761445    20966253    17994087    25244985    26823975    28648823    23537049    24495485    20075255    26108605    25401762    25830018    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    1482687    15979004    14709175    15632085    25315136    25348373    17550304    24845553    30249741    20798317    29403074   

EMBL

BABH01009338    BABH01009339    BABH01009340    NWSH01001238    PCG72011.1    MH606240    + More
AXM43807.1    KQ459589    KPI97479.1    KJ995807    AIN39490.1    ODYU01005682    SOQ46784.1    KPI97477.1    KQ459896    KPJ19443.1    KPJ19441.1    KPI97476.1    KPJ19444.1    BABH01009341    CH477371    EAT42428.1    CH478998    EAT32533.1    KQ971317    EEZ99172.1    JXUM01046680    KQ561486    KXJ78429.1    JTDY01000019    KOB79392.1    AF098717    AAC97504.1    ATLV01000829    ATLV01000830    KE523910    KFB34770.1    AAAB01008848    EAA07042.4    DS231994    EDS30856.1    AXCM01004244    ADMH02000540    ETN66032.1    DS232811    EDS45917.1    APCN01003535    AXCN02001762    UFQT01001180    SSX29359.1    SSX29360.1    KZ288187    PBC34719.1    CVRI01000064    CRL05204.1    CP012526    ALC47695.1    CH940652    EDW58924.2    CH933806    EDW13691.2    CH964272    KRF99908.1    EDW83879.1    KQ760645    OAD59676.1    GFXV01000266    MBW12071.1    GDHC01016379    JAQ02250.1    NNAY01001189    OXU24803.1    GECZ01023621    JAS46148.1    APGK01042097    APGK01042098    KB741002    KB631984    ENN75712.1    ERL87705.1    GAMC01010556    JAB95999.1    CH916369    EDV93847.1    JRES01000032    KNC34772.1    GBHO01004699    JAG38905.1    GDHC01005325    JAQ13304.1    GEBQ01006041    JAT33936.1    ABLF02037950    ABLF02037951    GBXI01013522    JAD00770.1    ACPB03011632    KQ414666    KOC65001.1    AE014297    AGB96034.1    ACZ94929.1    X68131    AY541497    BK002598    CM000070    EDY68158.2    CH479179    EDW25175.1    OUUW01000007    SPP83193.1    KA648374    AFP63003.1    CM000364    EDX12625.1    CCAG010018629    BT032711    ACD81725.1    CH902617    EDV42305.1    CH954181    EDV48771.1    GAKP01002543    GAKP01002542    JAC56410.1    GAKP01002541    JAC56411.1    JN003585    AEJ88361.1    CM000160    EDW96959.1    KQ434938    KZC12037.1    GDHF01011408    GDHF01008719    JAI40906.1    JAI43595.1    KPI97478.1    KQ435733    KOX77231.1    KK852427    KDR24107.1    QOIP01000004    RLU23752.1    GL447257    EFN86678.1    AJWK01024414    NEVH01006567    PNF37876.1    GBYB01007679    JAG77446.1    PYGN01001533    PSN34226.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000192223    UP000008820    + More
UP000007266    UP000069940    UP000249989    UP000075880    UP000037510    UP000069272    UP000030765    UP000075900    UP000075885    UP000007062    UP000002320    UP000075883    UP000000673    UP000076407    UP000075902    UP000075840    UP000075882    UP000075920    UP000075903    UP000075886    UP000075884    UP000075881    UP000242457    UP000005203    UP000183832    UP000092553    UP000008792    UP000009192    UP000076408    UP000091820    UP000007798    UP000215335    UP000019118    UP000030742    UP000002358    UP000001070    UP000037069    UP000007819    UP000015103    UP000095300    UP000053825    UP000000803    UP000192221    UP000001819    UP000008744    UP000268350    UP000095301    UP000000304    UP000092444    UP000007801    UP000008711    UP000002282    UP000076502    UP000092443    UP000053105    UP000027135    UP000279307    UP000008237    UP000092461    UP000235965    UP000245037   

PRIDE

H9JAH4    H9JAH5    Q01603   

Pfam

PF03098   An_peroxidase        + More
PF00012   HSP70
PF01404   Ephrin_lbd
PF14575   EphA2_TM
PF00041   fn3
PF07647   SAM_2

Interpro

IPR037120   Haem_peroxidase_sf_animal        + More
IPR019791   Haem_peroxidase_animal       
IPR029585   Pxd-like       
IPR010255   Haem_peroxidase_sf       
IPR013126   Hsp_70_fam       
IPR011641   Tyr-kin_ephrin_A/B_rcpt-like       
IPR008979   Galactose-bd-like_sf       
IPR001426   Tyr_kinase_rcpt_V_CS       
IPR003961   FN3_dom       
IPR027936   Eph_TM       
IPR009030   Growth_fac_rcpt_cys_sf       
IPR013783   Ig-like_fold       
IPR013761   SAM/pointed_sf       
IPR001090   Ephrin_rcpt_lig-bd_dom       
IPR036116   FN3_sf       
IPR001660   SAM       

SUPFAM

SSF48113   SSF48113        + More
SSF49785   SSF49785       
SSF47769   SSF47769       
SSF49265   SSF49265       
SSF57184   SSF57184       

Gene 3D

1.10.640.10     1.10.150.50     2.60.40.10    

CDD

cd00063  FN3

ProteinModelPortal

H9JAH4   A0A2A4JJ63   A0A346D9R6   A0A194PXJ3   A0A088MG66   A0A2H1W2P7   + More
A0A194PVX4   A0A194RNM9   A0A194RTJ6   A0A194PVR2   A0A194RPW2   A0A1W4WMG7   H9JAH5   Q177U0   Q16E76   D6WCM3   A0A182G7N2   A0A182IZD9   A0A0L7LVA3   A0A182FTE8   O96645   A0A084V9X6   A0A1Y9HDW6   A0A182PRL2   Q7QDZ3   B0WM28   A0A182MPT8   W5JNS3   B0XE84   A0A182WXU8   A0A182TM70   A0A182I5W9   A0A182KV49   A0A1Y9IWB3   A0A182VL61   A0A182Q218   A0A1Y9H2I7   A0A336MK45   A0A182KBY5   A0A336MHC5   A0A2A3EU99   A0A088AE09   A0A1J1J076   A0A0M4F792   B4M5J8   B4KC82   A0A182Y6T5   A0A1A9W584   A0A0Q9WVU0   B4NJ86   A0A310SND6   A0A2H8TD85   A0A146L6F1   A0A232F2X4   A0A1B6F7C3   N6UAQ6   W8C2M9   K7IYZ3   B4JHE0   A0A0L0CRA6   A0A0A9ZAS3   A0A146M0F8   A0A1B6MDD3   X1WIY8   A0A0A1WQI6   T1I7W3   A0A1I8NQ77   A0A0L7R2K3   A0A0B4KHM9   E1JIN0   Q01603   A0A1W4VTT3   B5DWL8   A0A1I8NQ80   B4G4K4   A0A3B0JQG5   T1PI65   B4QWD4   A0A1B0FFQ7   B3DMS3   B3M2B4   B3P3J1   A0A034WQE0   A0A034WLG7   I1T1H0   B4PM93   A0A154PJR6   A0A0K8VYA7   A0A194PWT3   A0A1A9Y5Z1   A0A0N0BI50   A0A067RJX3   A0A3L8DTW7   E2BCE2   A0A1B0CR56   A0A2J7RAM0   A0A0C9QVC3   A0A2P8XQD7  

PDB

5MFA     E-value=8.89092e-40,     Score=412

KEGG

101746811    K19511 peroxidase [EC:1.11.1.7] | (RefSeq) peroxidase-like

GO

GO:0042600   GO:0020037   GO:0004601   GO:0006979   GO:0016021   GO:0005003   GO:0005524   GO:0046872   GO:0007306   GO:0005576   GO:0042744   GO:0016491   GO:0004352   GO:0000287   GO:0003723   GO:0006270   GO:0042555   GO:0048384   GO:0055114  

PANTHER

PTHR11475:SF86  

Subcellular location

Secreted  

SignalP

Position:   1 - 18,         Likelihood:  0.744611

 

 

Length:

513

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

3.01833000000001

Exp number, first 60 AAs:

3.01387

Total prob of N-in:

0.14952

outside

1  -  513

 

 

Pi

192.009633

Theta

168.598814

Tajima's D

0.473905

CLR

0.289529

CSRT

0.503474826258687

Interpretation

Uncertain