Gene

KWMTBOMO03408

Pre Gene Modal

BGIBMGA006501

Annotation

PREDICTED:_uncharacterized_protein_LOC101743946_[Bombyx_mori]

Location

Bomo_Chr6(+):7078512-7081350      View in EpiBrowser

Full name

Mediator of RNA polymerase II transcription subunit 17      

Alternative Name

Mediator complex subunit 17

Location in the cell

Cytoplasmic   Reliability : 2.171

CDS

ATGTTCGAAACGCATTCTTTGACGGTTTTACCTTGTTCAAAAGAGAAAAAAACGGAAATTCACTACGGCATACTAACTGGTTCCTTCAATATGTATGATACTAAATTCGGTGGACGATCTAGAGGTAGACAAGCGATTACAATGAGCGTAATGGCCTACTGCTTGGCTTTTCATTATCATCCAAAACAATGGACCATGAAGCTTGTGGATAATTTAGTTAATGCCGGAGATCAATGGTACATTCAATGCTTAGAAAAGGTTCATGATCATTCTGCTGTGCAAGGAATGTGCGAAGTTTTGCAGTTCGGTAAGAAACAAACGCTTCTGCTAAACGGGAGAAGAATGCAAGTTTTGCTCGGCGAACCTGAAATTGTGGGGTACACGATGTCGTTAGACCCTACTGTTTATAATTTATGTAGAGGATTGAAAGTGTTTTTCAAAGAAAACCGTGCGGGCCTATTACTATCGAGGGTGTTGAAAGTTGTCGTCTGGAAAGATAAAGTATGCTATTACATATTTGATCCTGCTGGTAGAGATTCGCGAGCGTTCTCGAACTTCGCTAATGGAGCTGCTGCTCTTATAAATGTGAAAAATTTGGAAGCAGTAGCTGAAGTTCTTTTATCTCGTAGTGTACTAGACGACCAAAAGTACGTTTTGGCACCAGTTAAAGTTTTGAGAATGGTTGATGAAACCTGTGATGAAGATTTTGAATCTGATAAAGAACTTACTCAAACCGAAAAAGCTGTGATGGGATATAGAATACTTAATGAGAATTGTGCTATTGTTAACGCTACGATGCACTTGGGCGATCGGTGTTTTGAAGACGCTAAGTTTCGCCAAGCAATGCCGATAGCTATTATAGCAATGACCTACGCCAAAATTTCACCTCCGAATACATGGTTTACGAAAACATTGGACAAGATTTTACGATTAGGCAGCAAATTATACGTCGACTGTGCGCATCCGAAAACTTTAGTTGATTTAACAATTGACAATATACCGAATGTAATTAATGTCGGACCGTATGCGTGTGAAATCATTATATACAGAGAAAGAATTAAGGGCCAATTATTCACTACGAAAGAATGTTTATTTAACATCAAAACCGGTTTAGAAGATTTCTTCACTCATGAATATAATAGTGGAATACTAGAATTCAACAGTTATTGGCTGGGTGTTTGGAGGCAAAAAGATATGTTTTACTTATTCGATCCGTATCCGAGAACTAACGATGGTCTGCGGTCCGTTAATATTGGACGGGCTTGTTGTTGGATGCTTCTAAACACGGACACTATGGCGGATGTTTTCACAAAAAACTGGAATTATTTACCGGTTACAACTCAATTTTTTATTCATGCATTTAAAGTACTAAAATTAAAGAAAACAGAACCTAAGGCGCTACTACTTTGTACTTTAAGCGATGAACAATTACCGGGAACAAAAGTTAAAAGGAAGGTTTTACCGGTGAGTCAGGCGCACGGTGACGGTAGAGAAATAATACATGATGTTCTTCCACTAGAAGAATACGATGAGAAGGTTCCTGGAATACAAGCTATCGACGAGGAACGAATGGGTGACATTATTTCTCTAGTTGATAGTATCCAAGAAGACTATGTACCACCAATACCCTTAAAGTACAAAAATAAGGAACCAGAACCACTAGAAGCGAAAATTGAACTACCGCCAATTCACAAGAACTAG

Protein

MFETHSLTVLPCSKEKKTEIHYGILTGSFNMYDTKFGGRSRGRQAITMSVMAYCLAFHYHPKQWTMKLVDNLVNAGDQWYIQCLEKVHDHSAVQGMCEVLQFGKKQTLLLNGRRMQVLLGEPEIVGYTMSLDPTVYNLCRGLKVFFKENRAGLLLSRVLKVVVWKDKVCYYIFDPAGRDSRAFSNFANGAAALINVKNLEAVAEVLLSRSVLDDQKYVLAPVKVLRMVDETCDEDFESDKELTQTEKAVMGYRILNENCAIVNATMHLGDRCFEDAKFRQAMPIAIIAMTYAKISPPNTWFTKTLDKILRLGSKLYVDCAHPKTLVDLTIDNIPNVINVGPYACEIIIYRERIKGQLFTTKECLFNIKTGLEDFFTHEYNSGILEFNSYWLGVWRQKDMFYLFDPYPRTNDGLRSVNIGRACCWMLLNTDTMADVFTKNWNYLPVTTQFFIHAFKVLKLKKTEPKALLLCTLSDEQLPGTKVKRKVLPVSQAHGDGREIIHDVLPLEEYDEKVPGIQAIDEERMGDIISLVDSIQEDYVPPIPLKYKNKEPEPLEAKIELPPIHKN

Description

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Subunit

Component of the Mediator complex.

Similarity

Belongs to the Mediator complex subunit 17 family.
Belongs to the CD36 family.

Uniprot

A0A2A4JUW2   A0A194Q314   H9JAF6   A0A2H1V3K3   A0A194RPG6   U4UMF4   + More
N6TTE9   D2A3U8   E9J142   A0A0J7KY81   A0A195D4J2   F4X1W9   A0A195AZK9   A0A158NHM5   A0A0L7QQ13   A0A151X8G2   A0A3L8DH48   A0A026VX20   E2AMP4   A0A154PEP4   A0A0M8ZVQ3   A0A088AK98   A0A195EF44   A0A2A3EHH4   E2BXJ4   A0A195FVX9   A0A310SK39   K7JQK6   A0A232FIS3   A0A151XD23   A0A195DXV3   A0A1W4WHQ5   A0A1W4WSJ8   E2AM14   A0A195B7L8   A0A158NH87   A0A088AN91   A0A195FFJ7   A0A026WBK8   A0A3L8D8P5   A0A0J7NVE0   A0A2A3ECY6   D2A3U7   F4WZS6   K7J606   A0A151IID7   A0A1B0BRH5   U4URV6   A0A0M8ZN51   A0A1W4URZ4   A0A154PD72   A0A1A9XHP3   B4QRJ1   E9IUN7   B4HUE5   B3M3R4   A0A139WFY1   A0A139WFW1   A0A0K8UN95   Q961F4   A0A3B0JW13   Q9VRK6   B4PGE0   A0A0K8VTM6   A0A034VX85   B4IUC8   A0A034V5I3   A0A1B0AA95   A0A0K8UTE4   B4PIS4   A0A0A1XG16   A0A0L0BV69   N6SVA9   B4MM24   B4LFR0   A0A0A1XLB4   B4K1C3  

Pubmed

26354079    19121390    23537049    18362917    19820115    21282665    + More
21719571    21347285    30249741    24508170    20798317    20075255    28648823    17994087    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304    25348373    25830018    26108605   

EMBL

NWSH01000532    PCG75827.1    KQ459551    KPI99931.1    BABH01009250    BABH01009251    + More
ODYU01000517    SOQ35418.1    KQ459896    KPJ19402.1    KB632413    ERL95264.1    APGK01055245    APGK01055246    KB741261    ENN71636.1    KQ971348    EFA05571.2    GL767553    EFZ13454.1    LBMM01002130    KMQ95239.1    KQ976870    KYN07820.1    GL888555    EGI59556.1    KQ976694    KYM77641.1    ADTU01015621    KQ414792    KOC60728.1    KQ982409    KYQ56652.1    QOIP01000008    RLU19747.1    KK107672    EZA48180.1    GL440840    EFN65312.1    KQ434889    KZC10322.1    KQ435827    KOX71917.1    KQ979039    KYN23427.1    KZ288248    PBC31167.1    GL451265    EFN79563.1    KQ981208    KYN44810.1    KQ762196    OAD56142.1    NNAY01000160    OXU30430.1    KQ982294    KYQ58253.1    KQ980107    KYN17735.1    GL440703    EFN65534.1    KQ976574    KYM80189.1    ADTU01015272    KQ981625    KYN39158.1    KK107341    EZA52429.1    QOIP01000012    RLU16308.1    LBMM01001416    KMQ96360.1    KZ288292    PBC29152.1    EFA04883.1    GL888480    EGI60351.1    KQ977492    KYN02313.1    JXJN01019107    ERL95263.1    KQ436008    KOX67625.1    KQ434878    KZC09802.1    CM000363    CM002912    EDX09302.1    KMY97727.1    GL766012    EFZ15716.1    CH480817    EDW50566.1    CH902618    EDV40357.1    KYB26890.1    KYB26888.1    GDHF01024504    JAI27810.1    AY051621    AAK93045.1    OUUW01000002    SPP76911.1    AE014296    BT044431    AAF50789.1    ACH92496.1    CM000159    EDW95299.1    GDHF01010095    JAI42219.1    GAKP01012809    JAC46143.1    CH891852    EDW99991.2    GAKP01021550    JAC37402.1    GDHF01022468    JAI29846.1    EDW93494.1    GBXI01004437    JAD09855.1    JRES01001294    KNC23868.1    ENN71634.1    CH963847    EDW73033.2    CH940647    EDW69287.1    GBXI01002133    JAD12159.1    CH917051    EDV90390.1   

Proteomes

UP000218220    UP000053268    UP000005204    UP000053240    UP000030742    UP000019118    + More
UP000007266    UP000036403    UP000078542    UP000007755    UP000078540    UP000005205    UP000053825    UP000075809    UP000279307    UP000053097    UP000000311    UP000076502    UP000053105    UP000005203    UP000078492    UP000242457    UP000008237    UP000078541    UP000002358    UP000215335    UP000192223    UP000092460    UP000192221    UP000092443    UP000000304    UP000001292    UP000007801    UP000268350    UP000000803    UP000002282    UP000092445    UP000037069    UP000007798    UP000008792    UP000001070   

PRIDE

H9JAF6    Q961F4    Q9VRK6   

Pfam

PF10156   Med17        + More
PF04843   Herpes_teg_N
PF01130   CD36

Interpro

IPR019313   Mediator_Med17        + More
IPR006928   Herpes_teg_USP       
IPR038765   Papain-like_cys_pep_sf       
IPR002159   CD36_fam       

SUPFAM

SSF54001   SSF54001       

ProteinModelPortal

A0A2A4JUW2   A0A194Q314   H9JAF6   A0A2H1V3K3   A0A194RPG6   U4UMF4   + More
N6TTE9   D2A3U8   E9J142   A0A0J7KY81   A0A195D4J2   F4X1W9   A0A195AZK9   A0A158NHM5   A0A0L7QQ13   A0A151X8G2   A0A3L8DH48   A0A026VX20   E2AMP4   A0A154PEP4   A0A0M8ZVQ3   A0A088AK98   A0A195EF44   A0A2A3EHH4   E2BXJ4   A0A195FVX9   A0A310SK39   K7JQK6   A0A232FIS3   A0A151XD23   A0A195DXV3   A0A1W4WHQ5   A0A1W4WSJ8   E2AM14   A0A195B7L8   A0A158NH87   A0A088AN91   A0A195FFJ7   A0A026WBK8   A0A3L8D8P5   A0A0J7NVE0   A0A2A3ECY6   D2A3U7   F4WZS6   K7J606   A0A151IID7   A0A1B0BRH5   U4URV6   A0A0M8ZN51   A0A1W4URZ4   A0A154PD72   A0A1A9XHP3   B4QRJ1   E9IUN7   B4HUE5   B3M3R4   A0A139WFY1   A0A139WFW1   A0A0K8UN95   Q961F4   A0A3B0JW13   Q9VRK6   B4PGE0   A0A0K8VTM6   A0A034VX85   B4IUC8   A0A034V5I3   A0A1B0AA95   A0A0K8UTE4   B4PIS4   A0A0A1XG16   A0A0L0BV69   N6SVA9   B4MM24   B4LFR0   A0A0A1XLB4   B4K1C3  

KEGG

101743946    no KO assigned | (RefSeq) uncharacterized LOC101743946

GO

GO:0003712   GO:0006357   GO:0016592   GO:0016021  

PANTHER

PTHR11923  

Subcellular location

Nucleus  

Length:

566

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.1024

Exp number, first 60 AAs:

0.08311

Total prob of N-in:

0.00463

outside

1  -  566

 

 

Pi

164.249437

Theta

183.97911

Tajima's D

-0.549301

CLR

0.679401

CSRT

0.229138543072846

Interpretation

Uncertain