Gene

KWMTBOMO03339

Annotation

PREDICTED:_homeobox_protein_rough-like_[Papilio_polytes]

Location

Bomo_Chr6(-):4866232-4869036      View in EpiBrowser

Full name

Homeobox protein rough      

Transcription factor

Homeobox

Location in the cell

Nuclear   Reliability : 3.666

CDS

ATGGTGGCCCGGAGACGACGAAAAGAGAGTAGACCAAGACGACAGAGGACAACATTTTCAGCACATCAAACACTGCGATTAGAACTAGAGTACGCTAGAGGAGAATATGTTGCTAGAGCAAGAAGGTGTGAGTTAGCTTCGGCATTATCGTTAAGTGAAACCCAGGTTAAAATATGGTTTCAAAACAGAAGAGCCAAAGATAAAAGGATAGAGAAAGCGCAAATCGATCAACAATACAGGAATTTAGCTGCAGCCTCCGGTCTCTTCCCCACGGTACTCGGACCACCTTACTGCACCGCACCTGTTTGTCCATGTTTACCGGGGCCACAACCTTCAAGTATAGAGAAATAG

Protein

MVARRRRKESRPRRQRTTFSAHQTLRLELEYARGEYVARARRCELASALSLSETQVKIWFQNRRAKDKRIEKAQIDQQYRNLAAASGLFPTVLGPPYCTAPVCPCLPGPQPSSIEK

Description

Required to establish the unique cell identity of photoreceptors R2 and R5 and consequently for ommatidial assembly in the developing eye imaginal disk. Repression of expression in R8 photoreceptor by senseless (sens) is an essential mechanism of R8 cell fate determination.

Keywords

Complete proteome   Developmental protein   DNA-binding   Homeobox   Nucleus   Reference proteome   Sensory transduction   Transcription   Transcription regulation   Vision  

Feature

chain  Homeobox protein rough

Uniprot

A0A2A4IU88   A0A194RB78   A0A194Q350   A0A212F4M7   A0A336LQF5   A0A1B0GES9   + More
A0A1A9W5V9   Q16E75   E9IEE7   A0A182XIB3   E2A2V9   B0W367   D6WB35   A0A158NMJ3   B4GYV9   A0A232FF53   B4PSB8   A0A0C9Q8C4   B4IC03   B4QWT1   K7JKN7   A0A182Y781   Q29BA4   A0A0L0CQH6   A7USV8   A0A182LFE3   A0A182Q4V6   N6TSE8   A0A182TTF8   P10181   B3P894   A0A1W4VL16   C7E1Y4   A0A0U2K775   K1Q149  

Pubmed

26354079    22118469    17510324    21282665    20798317    18362917    + More
19820115    21347285    17994087    28648823    17550304    20075255    25244985    15632085    26108605    12364791    14747013    17210077    20966253    23537049    2903798    10731132    12537572    2898735    1974228    11709152    17252055    26580012    22992520   

EMBL

NWSH01007731    PCG62834.1    KQ460473    KPJ14525.1    KQ459551    KPI99982.1    + More
AGBW02010347    OWR48673.1    UFQT01000111    SSX20180.1    CCAG010012581    CH478999    EAT32532.1    GL762591    EFZ21034.1    GL436217    EFN72233.1    DS231831    EDS31210.1    KQ971311    EEZ99430.2    ADTU01020387    ADTU01020388    CH479198    EDW27977.1    NNAY01000306    OXU29332.1    CM000160    EDW98580.1    GBYB01010478    JAG80245.1    CH480828    EDW45161.1    CM000364    EDX14598.1    CM000070    EAL27094.3    JRES01000062    KNC34501.1    AAAB01008859    EDO64243.2    AXCN02000061    APGK01053965    KB741239    KB632275    ENN72175.1    ERL91143.1    M23629    AE014297    BT022142    X12528    CH954182    EDV53498.1    GQ240850    ACT36592.1    KT984254    ALR88651.1    JH817886    EKC27628.1   

Proteomes

UP000218220    UP000053240    UP000053268    UP000007151    UP000092444    UP000091820    + More
UP000008820    UP000076407    UP000000311    UP000002320    UP000007266    UP000005205    UP000008744    UP000215335    UP000002282    UP000001292    UP000000304    UP000002358    UP000076408    UP000001819    UP000037069    UP000007062    UP000075882    UP000075886    UP000019118    UP000030742    UP000075902    UP000000803    UP000008711    UP000192221    UP000005408   

PRIDE

P10181   

Pfam

PF00046   Homeodomain

Interpro

IPR009057   Homeobox-like_sf        + More
IPR020479   Homeobox_metazoa       
IPR000047   HTH_motif       
IPR001356   Homeobox_dom       
IPR017970   Homeobox_CS       

SUPFAM

SSF46689   SSF46689       

CDD

cd00086  homeodomain

ProteinModelPortal

A0A2A4IU88   A0A194RB78   A0A194Q350   A0A212F4M7   A0A336LQF5   A0A1B0GES9   + More
A0A1A9W5V9   Q16E75   E9IEE7   A0A182XIB3   E2A2V9   B0W367   D6WB35   A0A158NMJ3   B4GYV9   A0A232FF53   B4PSB8   A0A0C9Q8C4   B4IC03   B4QWT1   K7JKN7   A0A182Y781   Q29BA4   A0A0L0CQH6   A7USV8   A0A182LFE3   A0A182Q4V6   N6TSE8   A0A182TTF8   P10181   B3P894   A0A1W4VL16   C7E1Y4   A0A0U2K775   K1Q149  

PDB

6ES2     E-value=1.56904e-10,     Score=152

KEGG

105842248    K09362 homeo domain only family, other | (RefSeq) homeobox protein rough

GO

GO:0006355   GO:0043565   GO:0005634   GO:0007463   GO:0042067   GO:0045944   GO:0001012   GO:0000978   GO:0003700   GO:0048054   GO:0050896   GO:0007601   GO:0003677   GO:0005515   GO:0033177   GO:0000287   GO:0003723   GO:0006270   GO:0042555   GO:0048384  

Subcellular location

Nucleus  

Length:

116

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.81899

Exp number, first 60 AAs:

0.00034

Total prob of N-in:

0.77775

inside

1  -  116

 

 

Pi

182.902299

Theta

123.158306

Tajima's D

1.523193

CLR

0

CSRT

0.794010299485026

Interpretation

Uncertain