Gene

KWMTBOMO03319  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA006411

Annotation

PREDICTED:_vacuolar_protein_sorting-associated_protein_16_homolog_[Plutella_xylostella]

Location

Bomo_Chr6(-):4199732-4213810      View in EpiBrowser

Full name

Vacuolar protein sorting-associated protein 16 homolog      

Location in the cell

Cytoplasmic   Reliability : 2.098

CDS

ATGTCGGCTCTACTAACAGCTGATTGGTTCCAACTGGACACATATTATCGAAAATTTGATCTCTACACAATGAACTGGATGATGGACGAAGGTTTAGAGAATATGATAGTTAGCGGTGCACCGTATGGTGGCCCAATGGCAGTAGTGAGAGACCGTAAACAATTTGTTCAAATAAAAACCACCACTAAACCTGTTATAACAATCTACAACTGCTCAGGAAATGTTATATCAAAGATATTGTGGAACAGTGGTGTCCTACTACATATCGGATGGTCTGATGGGGAACAGCTACTTTGTATTCAAGAAAGCGGTGATGTCCTTATTTATGACATGTTTGGAGCTTACCAGAAAACTTTCAATATGGGCCAAGAAGTCAGAGATACAAAAGTTTGTAAAGCTCAATTGTTTCCAAATCCTCATGGTATAGGACTAGCTGTTATCACTACAACTAATAGAATGTTCCTTGTGAGTAATGTTTCTGAACCAAAAGCTCGACCGGTTCCTGATATACCAAGAGCCAATGAACCGATATCATGCTGGTGCGCTGTAAACTCTAGTTTTATAGTGTGTCGAGATAAAGAGATTTATAAATGCCAACTAGGTGAATCCAGGGCCATTCTTTTGCGTCCAGAAATCAAGAACCCCTACACACAGATCCTATCTATCGTGGCTTCACAGAATGGCAAGCACATTGCGTTCTTTACCGACTCTGGTTTCCTATGGATTGGATCTTCCGATTTGAGGAATAATTACTGCGAGTTAGATACGGATTATATTAAACAACCCAAAGAATTCATGTGGTGCGGTTCCCAAGCTGTGGCCGCACACTGGGACGACACTTTGTGCATGTACGGTACTAAAGGCAATAGTGTTGCGTATCCATACGATGGACCCTTCCACTTAATTCAGGAGATGGACTGCATACGTATTGTATCAGAAATGACCCATGAACTCGTGCAAAAGGTGCCTTTTGTTGTTGAGAAAATATTCCGGATCAATAGCACGGCGCCCGGCTCGTACCTAGTTGAAGCTTCTAAGCAATTTCAGAAACGCAGTCACCGAGCTGACGAGTACATCCGGCTGGTGAAGCCCGACCTGTCCGCCGCCGTCGCGGACTGCATCGAGGCAGCCGCCTTCGAGTTCAGTCCGGACGTGCAGAAAATGTTGATCCGGGCCGCGCAGTTCGGGAAATGCTTCCTGATGGACCCCGTCATCACGGAGCTCTACGTCAAGACGTGTCGCTGGTTGAGAGTTCTGAACGCCGTCAGAGATCCTAAAGTGGCTATACCTTTGACGTCTATGCAAATGCGTAATTTGGGCGAACGAATACTTCTTGACCGGCTCATATGGCGCCGACTGCACTGTTTGGCCGGACACATCGCTTCCTACCTGCAACTGAAGGATGGACGCACGAGAGTCCTGTCCCATTGGGCTTGTTACAAGGTAACTCAGCCTCACTTGGACAACGAGAGTGCCGCAAGGGAGATAGGCGAGAAGCTACGGAATGTCCCTGGTATATCGTACACAACGATAGCCATGAAAGCTGCCGAAAAAGGAAGGAAAGCTCTCGCTATAAAAATCCTGGAGTACGAGGCACATAGCAAATTACAAGTTCCATTACTATTGTCACTCGGCGAAGGTCCGACTGCGCTGCTGAAGGCGACCGCCAGCGGCGACACGGACTTGGTCTACGTTGTTCTGTTGCATCTCAAGGAAAAAATGGGAAAACATGACTTTGAGCTCACGATCCGCAGTTTCCCTTTAGCGCACGCCCTGTACATCAAGTACTGCGCAAGTCACAACCGCGAGGCCCTGCGCCTGGTCTACGTTCAGGAGGACGACTTCCAGGGTCAGGCCGCCACTCACATATGTGACGCCATCGAGCAGACCAACCCGGGCAGCGCGGAGGCCTCGCTGATATCCGCCAGGGAATGTTACAAAAAGGGCAAAAACGAATTAGGTGCATCTGTATGCGAGGACGCCCGGAAGCTGTGCAAGCAACAGTCCAGTCTCCAGGAGACGTACGGAACGAGCTTCGTGGGGCTGTCGCTTCACGATACCGTCAAAAAGCTTCTGGACCAAGGAGAAGTCAGATTGGCGGACAAACTGCGATCGGAATATAAAATGCCCGATCGAAGATATTGGTGGCTTCGTATCCTAACACTAGCCGAGAAGTCCAATTGGGAGGAATTGGATAAGTTTTCGAAATCAAAGAAATCTCCAGTCGGGTACGAGCCGTTTGTCGACGCCTGTCTCAAGTACAACAAGGCGGACGAAGCACTCAAGTACTTGCCGAGATGCAGGGATGAGATCAAAATTAAATACTACGTCAAAGCTGGGTATTACGCGGAGGCCGCCGAAGTAGCATACGAACAGAAAGACGAAGCCGGCTTACATTTCGTTCAAAACAAATGCCCGATGCAAGACTTCGACAATCAAGCCAAAATATCAGGACTCCTAGAACAGTTGAAAATTAAGAAATGA

Protein

MSALLTADWFQLDTYYRKFDLYTMNWMMDEGLENMIVSGAPYGGPMAVVRDRKQFVQIKTTTKPVITIYNCSGNVISKILWNSGVLLHIGWSDGEQLLCIQESGDVLIYDMFGAYQKTFNMGQEVRDTKVCKAQLFPNPHGIGLAVITTTNRMFLVSNVSEPKARPVPDIPRANEPISCWCAVNSSFIVCRDKEIYKCQLGESRAILLRPEIKNPYTQILSIVASQNGKHIAFFTDSGFLWIGSSDLRNNYCELDTDYIKQPKEFMWCGSQAVAAHWDDTLCMYGTKGNSVAYPYDGPFHLIQEMDCIRIVSEMTHELVQKVPFVVEKIFRINSTAPGSYLVEASKQFQKRSHRADEYIRLVKPDLSAAVADCIEAAAFEFSPDVQKMLIRAAQFGKCFLMDPVITELYVKTCRWLRVLNAVRDPKVAIPLTSMQMRNLGERILLDRLIWRRLHCLAGHIASYLQLKDGRTRVLSHWACYKVTQPHLDNESAAREIGEKLRNVPGISYTTIAMKAAEKGRKALAIKILEYEAHSKLQVPLLLSLGEGPTALLKATASGDTDLVYVVLLHLKEKMGKHDFELTIRSFPLAHALYIKYCASHNREALRLVYVQEDDFQGQAATHICDAIEQTNPGSAEASLISARECYKKGKNELGASVCEDARKLCKQQSSLQETYGTSFVGLSLHDTVKKLLDQGEVRLADKLRSEYKMPDRRYWWLRILTLAEKSNWEELDKFSKSKKSPVGYEPFVDACLKYNKADEALKYLPRCRDEIKIKYYVKAGYYAEAAEVAYEQKDEAGLHFVQNKCPMQDFDNQAKISGLLEQLKIKK

Description

Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes.

Similarity

Belongs to the VPS16 family.

Uniprot

H9JA66   A0A194R5G4   A0A194Q381   A0A2A4ITH3   A0A1E1WMG7   A0A067RW40   + More
A0A2J7RED3   D7GXI5   A0A1W4XG90   F4WMZ2   A0A195FUF2   A0A158NSJ7   A0A151WIB8   A0A151HYW3   E2A495   A0A0C9QK40   E9JD91   A0A1Y1NG99   A0A151J431   E2B833   A0A0L7RDQ4   A0A1B6KXY6   A0A232F043   A0A310SG39   A0A154PAW8   A0A0C9R7F3   A0A2A3EFJ4   A0A023F2B4   A0A087ZYS2   A0A069DX66   E0VS77   A0A0P4VTH1   T1HR96   A0A1B0GLC8   R7VKD8   A0A1S3I6Y6   A0A336MYR0   A0A1L8DVT0   A0A1D2MTX4   A0A0P6FJG8   A0A0P5PBJ2   A0A087TTA1   A0A164Y9W7   A0A0P6GMG9   A0A0P5U117   A0A0P5B543   E9HJU2   A0A0P6EPB5   A0A226D3J7   A0A0A9X2X7   W4ZC77   A0A0P5RPQ7   A0A0P4YGN6   A0A0B7AXF7   A0A0P6I948   A0A0N8DNG6   A0A1J1I0H2   A0A0P5B285   B0W200   A0A1Q3FAJ4   K1PWU7   Q16SL9   A0A131YNZ8   A0A0N8AT84   A0A224ZBT6   A0A146LUE5   A0A182G9E2   A0A131XNR4   A0A0P5DTV2   A0A0P5N1E1   A0A210PVW1   A0A1A9WZ26   A0A0L0CIS0   A0A0P5CWU8   V4AP47   A0A1I8Q4M5   A0A0P5U1Z6   A0A0P6G4M8   W8BDD4   A0A182YMX9   A0A2S2QA28   A0A2B4S3T7   A0A182R9J2   A0A1I8NI14   A0A182ILF1   A0A182K7D2   A0A0P6ES34   A0A0A1XM34   J9JWL8   A0A1E1XSW3   A0A2T7PR81   A0A1B0BHP4   A0A084VIW0   A0A182UXI3   A0A182SFP9   A0A131Y4C9   A0A182KYB5   Q7QFJ5   B4K623  

Pubmed

19121390    26354079    24845553    18362917    19820115    21719571    + More
21347285    20798317    21282665    28004739    28648823    25474469    26334808    20566863    27129103    23254933    27289101    21292972    25401762    22992520    17510324    26830274    28797301    26823975    26483478    28049606    28812685    26108605    24495485    25244985    25315136    25830018    29209593    24438588    20966253    12364791    14747013    17210077    17994087   

EMBL

BABH01009017    BABH01009018    KQ460685    KPJ12917.1    KQ459551    KPI99996.1    + More
NWSH01008438    PCG62554.1    GDQN01002841    JAT88213.1    KK852427    KDR24089.1    NEVH01005277    PNF39187.1    KQ971382    EFA13302.2    GL888223    EGI64462.1    KQ981261    KYN44083.1    ADTU01024980    KQ983089    KYQ47592.1    KQ976720    KYM76718.1    GL436596    EFN71766.1    GBYB01003919    JAG73686.1    GL771866    EFZ09129.1    GEZM01003788    GEZM01003787    GEZM01003786    GEZM01003785    JAV96568.1    KQ980211    KYN17190.1    GL446282    EFN88125.1    KQ414613    KOC68949.1    GEBQ01023670    JAT16307.1    NNAY01001413    OXU24054.1    KQ761768    OAD57104.1    KQ434864    KZC09045.1    GBYB01003920    JAG73687.1    KZ288269    PBC29926.1    GBBI01003583    JAC15129.1    GBGD01000488    JAC88401.1    DS235745    EEB16233.1    GDKW01000769    JAI55826.1    ACPB03014376    AJWK01034746    AMQN01016953    KB292583    ELU17286.1    UFQS01003893    UFQT01003893    SSX16017.1    SSX35350.1    GFDF01003546    JAV10538.1    LJIJ01000528    ODM96537.1    GDIQ01063445    JAN31292.1    GDIQ01152610    GDIQ01136571    GDIQ01073931    JAK99115.1    KK116633    KFM68340.1    LRGB01000930    KZS15033.1    GDIQ01031470    JAN63267.1    GDIP01119281    JAL84433.1    GDIP01189516    JAJ33886.1    GL732664    EFX68012.1    GDIQ01059745    JAN34992.1    LNIX01000040    OXA39231.1    GBHO01029250    JAG14354.1    AAGJ04016044    AAGJ04016045    GDIQ01106623    JAL45103.1    GDIP01227915    JAI95486.1    HACG01037725    CEK84590.1    GDIQ01009513    JAN85224.1    GDIP01016519    JAM87196.1    CVRI01000036    CRK93076.1    GDIP01195167    JAJ28235.1    DS231824    EDS27436.1    GFDL01010441    JAV24604.1    JH816093    EKC23509.1    CH477672    EAT37446.1    GEDV01007870    JAP80687.1    GDIQ01245187    JAK06538.1    GFPF01013224    MAA24370.1    GDHC01008277    JAQ10352.1    JXUM01050240    KQ561640    KXJ77917.1    GEFH01000344    JAP68237.1    GDIP01151670    JAJ71732.1    GDIQ01148472    JAL03254.1    NEDP02005459    OWF40606.1    JRES01000338    KNC32150.1    GDIP01164534    JAJ58868.1    KB201459    ESO96565.1    GDIP01119282    JAL84432.1    GDIQ01057145    JAN37592.1    GAMC01009853    JAB96702.1    GGMS01005395    MBY74598.1    LSMT01000173    PFX24561.1    GDIQ01059744    JAN34993.1    GBXI01007435    GBXI01002226    JAD06857.1    JAD12066.1    ABLF02018142    ABLF02018146    GFAA01001036    JAU02399.1    PZQS01000002    PVD35929.1    JXJN01014484    ATLV01013411    KE524855    KFB37904.1    GEFM01002890    JAP72906.1    AAAB01008846    EAA06254.3    CH933806    EDW16260.1   

Proteomes

UP000005204    UP000053240    UP000053268    UP000218220    UP000027135    UP000235965    + More
UP000007266    UP000192223    UP000007755    UP000078541    UP000005205    UP000075809    UP000078540    UP000000311    UP000078492    UP000008237    UP000053825    UP000215335    UP000076502    UP000242457    UP000005203    UP000009046    UP000015103    UP000092461    UP000014760    UP000085678    UP000094527    UP000054359    UP000076858    UP000000305    UP000198287    UP000007110    UP000183832    UP000002320    UP000005408    UP000008820    UP000069940    UP000249989    UP000242188    UP000091820    UP000037069    UP000030746    UP000095300    UP000076408    UP000225706    UP000075900    UP000095301    UP000075880    UP000075881    UP000007819    UP000245119    UP000092460    UP000030765    UP000075903    UP000075901    UP000075882    UP000007062    UP000009192   

PRIDE

H9JA66   

Pfam

PF04840   Vps16_C        + More
PF04841   Vps16_N

Interpro

IPR006925   Vps16_C        + More
IPR036322   WD40_repeat_dom_sf       
IPR016534   VPS16       
IPR038132   Vps16_C_sf       
IPR006926   Vps16_N       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR011047   Quinoprotein_ADH-like_supfam       

SUPFAM

SSF50978   SSF50978        + More
SSF50998   SSF50998       

Gene 3D

1.10.150.780     2.130.10.10    

ProteinModelPortal

H9JA66   A0A194R5G4   A0A194Q381   A0A2A4ITH3   A0A1E1WMG7   A0A067RW40   + More
A0A2J7RED3   D7GXI5   A0A1W4XG90   F4WMZ2   A0A195FUF2   A0A158NSJ7   A0A151WIB8   A0A151HYW3   E2A495   A0A0C9QK40   E9JD91   A0A1Y1NG99   A0A151J431   E2B833   A0A0L7RDQ4   A0A1B6KXY6   A0A232F043   A0A310SG39   A0A154PAW8   A0A0C9R7F3   A0A2A3EFJ4   A0A023F2B4   A0A087ZYS2   A0A069DX66   E0VS77   A0A0P4VTH1   T1HR96   A0A1B0GLC8   R7VKD8   A0A1S3I6Y6   A0A336MYR0   A0A1L8DVT0   A0A1D2MTX4   A0A0P6FJG8   A0A0P5PBJ2   A0A087TTA1   A0A164Y9W7   A0A0P6GMG9   A0A0P5U117   A0A0P5B543   E9HJU2   A0A0P6EPB5   A0A226D3J7   A0A0A9X2X7   W4ZC77   A0A0P5RPQ7   A0A0P4YGN6   A0A0B7AXF7   A0A0P6I948   A0A0N8DNG6   A0A1J1I0H2   A0A0P5B285   B0W200   A0A1Q3FAJ4   K1PWU7   Q16SL9   A0A131YNZ8   A0A0N8AT84   A0A224ZBT6   A0A146LUE5   A0A182G9E2   A0A131XNR4   A0A0P5DTV2   A0A0P5N1E1   A0A210PVW1   A0A1A9WZ26   A0A0L0CIS0   A0A0P5CWU8   V4AP47   A0A1I8Q4M5   A0A0P5U1Z6   A0A0P6G4M8   W8BDD4   A0A182YMX9   A0A2S2QA28   A0A2B4S3T7   A0A182R9J2   A0A1I8NI14   A0A182ILF1   A0A182K7D2   A0A0P6ES34   A0A0A1XM34   J9JWL8   A0A1E1XSW3   A0A2T7PR81   A0A1B0BHP4   A0A084VIW0   A0A182UXI3   A0A182SFP9   A0A131Y4C9   A0A182KYB5   Q7QFJ5   B4K623  

PDB

5BV1     E-value=5.4052e-37,     Score=390

KEGG

101738269    K20180 vacuolar protein sorting-associated protein 16 | (RefSeq) vacuolar protein sorting-associated

GO

GO:0007033   GO:0030897   GO:0031902   GO:0006886   GO:0005765   GO:0033263   GO:0005737   GO:0003779   GO:0035542   GO:0005768   GO:0032889   GO:0016197   GO:0008057   GO:0005829   GO:0005776   GO:0034058   GO:0097352   GO:0008333   GO:0019905   GO:0009267   GO:0005515   GO:0033177   GO:0000287   GO:0003723   GO:0006270   GO:0042555   GO:0048384  

PANTHER

PTHR12811  

Subcellular location

Late endosome membrane   Cytoplasmic, peripheral membrane protein associated with late endosomes/lysosomes.   With evidence from 1 publications.
Lysosome membrane   Cytoplasmic, peripheral membrane protein associated with late endosomes/lysosomes.   With evidence from 1 publications.

Length:

827

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0700000000000001

Exp number, first 60 AAs:

0.0298

Total prob of N-in:

0.00188

outside

1  -  827

 

 

Pi

195.396331

Theta

168.296407

Tajima's D

0.527904

CLR

0

CSRT

0.517174141292935

Interpretation

Uncertain