Gene

KWMTBOMO03317  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA006412

Annotation

PREDICTED:_ATP_synthase_lipid-binding_protein?_mitochondrial_[Bombyx_mori]

Location

Bomo_Chr6(-):4185473-4188460      View in EpiBrowser

Full name

ATP synthase subunit c       + More
ATP synthase lipid-binding protein, mitochondrial      

Alternative Name

ATP synthase F(0) sector subunit c
F-type ATPase subunit c
Lipid-binding protein
ATPase protein 9
ATPase subunit c

Location in the cell

Mitochondrial   Reliability : 1.753 PlasmaMembrane   Reliability : 2.143

CDS

ATGCTGTCTGCCGCCAGACTGATCGCCCCTGCAGCCAGGTCTGCCATCTTCTGCAACTCTGCACTGGTGCGACCACTTGCAGCAGTACCCACCCATACACAGATGGTACCTGCTGTCCCTACACAGCTCTCTGCAGTGCGGTCCTTCCAGACCACATCGGTCACTAAGGACATTGACTCTGCTGCCAAATTCATTGGTGCTGGTGCAGCGACAGTGGGAGTAGCTGGTTCCGGAGCTGGTATTGGAACAGTCTTCGGCTCCCTCATCATCGGCTATGCCAGGAACCCCTCCCTCAAGCAGCAGTTGTTCTCATACGCCATTCTGGGTTTCGCCTTGTCTGAGGCTATGGGTCTGTTCTGTCTTATGATGGCGTTCCTGCTGCTCTTCGCTTTCTAA

Protein

MLSAARLIAPAARSAIFCNSALVRPLAAVPTHTQMVPAVPTQLSAVRSFQTTSVTKDIDSAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLLLFAF

Description

F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element (By similarity).

Subunit

F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

Similarity

Belongs to the ATPase C chain family.

Keywords

Hydrogen ion transport   Ion transport   Lipid-binding   Membrane   Methylation   Mitochondrion   Transit peptide   Transmembrane   Transmembrane helix   Transport  

Feature

chain  ATP synthase subunit c

Uniprot

A0A3G1T1C9   A0A3B0E4A8   Q9U505   A0A1E1WK31   A0A0L7LHM8   A0A076FLZ2   + More
A0A2H1W6R3   I4DM35   I4DIK3   A0A212FKT3   A0A194R6P8   R4WHV9   A0A2P8XFA1   A0A3B4AN32   A0A067RJV5   C1BKB8   A0A1D1Y9C8   A0A0L7RB10   A0A3B4AMJ9   Q06DF7   A0A1I8JV93   A0A182IAB9   A0A182P7T5   A0A182LTA9   A0A182TS18   A0A182KYB2   A0A182XEF4   A7USF7   F1RWF6   A0A195DQM6   E2AC98   A0A3B5KMJ4   A0A023F9P0   A0A182YMX6   A0A182N078   A0A084VIW3   A0A1B0EY42   A0A0J7LBH3   A0A3P9AM30   C4N187   A0A182QH23   A0A1I8PHQ8   A0A3P9NDT9   A0A182J0U9   A0A182R9I8   A0A2U4AHQ6   A0A0S7GC10   A0A3P9NDT3   A0A3B3QNT0   A0A087XQH9   A0A2R7WMU1   A0A1A8R7Y3   A0A1A8KRI5   A0A1A8NUD0   A0A1A7YZA8   A0A1A8E919   A0A1A8GK12   A0A1A8AE94   A0A3B3Y0B6   M3ZDW0   A0A3B3UNB3   A0A060WWW1   B5DGN3   A0A151I5Z8   A0A158NAN0   F4W6W0   A0A195EWK9   A0A3B3U0T0   Q201X0   A0A1A9XUC5   A0A1A9UWX7   A0A1B0BHP6   A0A1B0AJW1   A0A1A9WZ22   D3TRM4   A0A158NAM9   T1DJ07   A0A1Q3FI93   B0WM99   Q1KKT5   B5XFQ8   Q29570   A0A1A8E7A0   A0A1A8FSE8   A0A1A8UWL5   A0A2M4A0W9   A0A1B6G2G8   A0A1S3A677   A0A182KA43   A0A3P8V4E0   A0A2U4AHM7   A0A2Y9LW16  

Pubmed

10620045    26227816    22651552    26354079    22118469    23691247    + More
29403074    25463417    24845553    17244545    20966253    12364791    14747013    17210077    20798317    21551351    25474469    25244985    24438588    25069045    19576987    29240929    23542700    24755649    19878547    20433749    21347285    21719571    20353571    24330624    16636282    8672129    24487278   

EMBL

MG846938    AXY94790.1    RBVL01000231    RKO10346.1    AF117583    GDQN01009827    + More
GDQN01004041    GDQN01003684    GDQN01001743    GDQN01000082    JAT81227.1    JAT87013.1    JAT87370.1    JAT89311.1    JAT90972.1    JTDY01001076    KOB74957.1    KF803646    AII16888.1    ODYU01006696    SOQ48771.1    AK402353    BAM18975.1    AK401121    KQ459551    BAM17743.1    KPI99998.1    AGBW02007989    OWR54348.1    KQ460685    KPJ12915.1    AK416940    BAN20155.1    PYGN01002371    PSN30634.1    KK852427    KDR24087.1    BT075047    ACO09471.1    GDJX01016694    JAT51242.1    KQ414618    KOC67926.1    DQ910368    ABI83790.1    APCN01001140    AXCM01000565    AAAB01008846    EDO64318.1    AEMK02000080    KQ980612    KYN15168.1    GL438484    EFN68944.1    GBBI01001074    JAC17638.1    ATLV01013412    KE524855    KFB37907.1    AJVK01007418    LBMM01000031    KMR05262.1    EZ048860    ACN69152.1    AXCN02001257    GBYX01457045    GBYX01457044    JAO24499.1    AYCK01005506    KK855016    PTY20320.1    HAEH01014922    HAEI01016825    SBS01364.1    HAED01021143    HAEE01015045    SBR35095.1    HAEF01019196    HAEG01004852    SBR72661.1    HADW01011579    HADX01013271    SBP35503.1    HADZ01006361    HAEA01013114    SBQ41594.1    HAEB01017935    HAEC01003420    SBQ71497.1    HADY01014065    HAEJ01018056    SBP52550.1    FR904793    CDQ71838.1    BT043792    BT046489    BT058350    BT060050    ACH70907.1    ACI66290.1    ACN10063.1    ACN12410.1    KQ976413    KYM90349.1    ADTU01010396    GL887762    EGI70073.1    KQ981954    KYN32282.1    ABLF02033112    DQ413216    AK343131    ABD72684.1    BAH72902.1    JXJN01014481    EZ424076    EZ424078    ADD20352.1    ADD20354.1    GALA01000611    JAA94241.1    GFDL01007781    JAV27264.1    DS231996    EDS30948.1    DQ481668    ABF22459.1    BT049877    ACI69678.1    F14506    CAA23094.1    HADZ01004304    HAEA01012499    SBQ40979.1    HAEB01014527    HAEC01004864    SBQ61054.1    HADY01024320    HAEJ01011265    SBS51722.1    GGFK01001088    MBW34409.1    GECZ01026928    GECZ01015112    GECZ01013276    JAS42841.1    JAS54657.1    JAS56493.1   

Proteomes

UP000276569    UP000037510    UP000053268    UP000007151    UP000053240    UP000245037    + More
UP000261520    UP000027135    UP000053825    UP000075903    UP000075840    UP000075885    UP000075883    UP000075902    UP000075882    UP000076407    UP000007062    UP000008227    UP000078492    UP000000311    UP000005226    UP000076408    UP000075884    UP000030765    UP000092462    UP000036403    UP000265140    UP000075886    UP000095300    UP000242638    UP000075880    UP000075900    UP000245320    UP000261540    UP000028760    UP000261480    UP000002852    UP000261500    UP000193380    UP000087266    UP000078540    UP000005205    UP000007755    UP000078541    UP000007819    UP000092443    UP000078200    UP000092460    UP000092445    UP000091820    UP000002320    UP000079721    UP000075881    UP000265120    UP000248483   

PRIDE

F1RWF6   

Pfam

PF00137   ATP-synt_C

Interpro

IPR020537   ATP_synth_F0_csu_DDCD_BS        + More
IPR038662   ATP_synth_F0_csu_sf       
IPR002379   ATPase_proteolipid_c-like_dom       
IPR035921   F/V-ATP_Csub_sf       
IPR000454   ATP_synth_F0_csu       

SUPFAM

SSF81333   SSF81333       

Gene 3D

1.20.20.10    

ProteinModelPortal

A0A3G1T1C9   A0A3B0E4A8   Q9U505   A0A1E1WK31   A0A0L7LHM8   A0A076FLZ2   + More
A0A2H1W6R3   I4DM35   I4DIK3   A0A212FKT3   A0A194R6P8   R4WHV9   A0A2P8XFA1   A0A3B4AN32   A0A067RJV5   C1BKB8   A0A1D1Y9C8   A0A0L7RB10   A0A3B4AMJ9   Q06DF7   A0A1I8JV93   A0A182IAB9   A0A182P7T5   A0A182LTA9   A0A182TS18   A0A182KYB2   A0A182XEF4   A7USF7   F1RWF6   A0A195DQM6   E2AC98   A0A3B5KMJ4   A0A023F9P0   A0A182YMX6   A0A182N078   A0A084VIW3   A0A1B0EY42   A0A0J7LBH3   A0A3P9AM30   C4N187   A0A182QH23   A0A1I8PHQ8   A0A3P9NDT9   A0A182J0U9   A0A182R9I8   A0A2U4AHQ6   A0A0S7GC10   A0A3P9NDT3   A0A3B3QNT0   A0A087XQH9   A0A2R7WMU1   A0A1A8R7Y3   A0A1A8KRI5   A0A1A8NUD0   A0A1A7YZA8   A0A1A8E919   A0A1A8GK12   A0A1A8AE94   A0A3B3Y0B6   M3ZDW0   A0A3B3UNB3   A0A060WWW1   B5DGN3   A0A151I5Z8   A0A158NAN0   F4W6W0   A0A195EWK9   A0A3B3U0T0   Q201X0   A0A1A9XUC5   A0A1A9UWX7   A0A1B0BHP6   A0A1B0AJW1   A0A1A9WZ22   D3TRM4   A0A158NAM9   T1DJ07   A0A1Q3FI93   B0WM99   Q1KKT5   B5XFQ8   Q29570   A0A1A8E7A0   A0A1A8FSE8   A0A1A8UWL5   A0A2M4A0W9   A0A1B6G2G8   A0A1S3A677   A0A182KA43   A0A3P8V4E0   A0A2U4AHM7   A0A2Y9LW16  

PDB

5FIL     E-value=8.74096e-11,     Score=154

KEGG

101738009    K02128 F-type H+-transporting ATPase subunit c | (RefSeq) ATP synthase lipid-binding protein, mitoch

PATHWAY

00190    Oxidative phosphorylation - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016021   GO:0006811   GO:0008289   GO:0005886   GO:0045263   GO:0046933   GO:0015991   GO:0015986   GO:0031966   GO:0015078   GO:0000276   GO:0033177   GO:0000287   GO:0003723   GO:0006270   GO:0042555   GO:0048384  

PANTHER

PTHR10031  

Subcellular location

Cell membrane  
Mitochondrion membrane  

Length:

131

Number of predicted TMHs:

2

Exp number of AAs in TMHs:

47.54873

Exp number, first 60 AAs:

1.11726

Total prob of N-in:

0.45406

inside

1  -  69

TMhelix

70  -  92

outside

93  -  106

TMhelix

107  -  129

inside

130  -  131

 

 

Pi

252.497225

Theta

204.73786

Tajima's D

0.622887

CLR

0.059693

CSRT

0.560221988900555

Interpretation

Uncertain