Gene

KWMTBOMO03307  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA006419

Annotation

PREDICTED:_malate_dehydrogenase_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr6(-):3989303-4022501      View in EpiBrowser

Full name

Malic enzyme      

Location in the cell

Cytoplasmic   Reliability : 1.356

CDS

ATGGAATATTTGTCGCGCACTATGAATGGCAACAGCGGCAAATGTCAAGTTAATGGCACGGTCCGCGACATTCGGGAAATGAAAAGGAGCGAATCCGCAATGAGTCCAGCGCCCCCCGCTCACTGTAACAAAACTGGCGTTCCGTTCTCGGCAGTCAAGCAGTCGCAAGCGACAAGCGGAGGGAAGTGTACGTATAGCGAAATGGAACGTGATCGTATCGGATTATGGGGCTCCGGGGACGGACAGCCCACCAGCGGCCTCTCCGGCCTCGACCACCTCAAGCACCCCGGCCTCAACAAGGGTATGGCTTTTACCATCGAAGAGCGTCAGCTCTTGGGGATCCACGGGTTGTTACCACCACGAGTCAAGACGCAAGAGGAGCAGGTTGAACTATGCAAGCTCTCGATCGACAGATACGAAAATCCACTTAACAAGTACATCTATCTTATGGGGCTCTTGGACCGCAATGAGCATCTGTTCTACCGTTTCGTCGCGGATAACGTGGCTGAAATGATGCCAATTGTGTACACTCCGACGGTTGGCCTGGCCTGTCAGAAGTTCGGCCTTGTGTACCGCCGACCAAGGGGCCTCTTCATCACGATCCACGATAAGGGACATGTATACGATGTTCTTAAGAACTGGCCGGAGACGGACGTCCGCGCCATTGTTGTAACCGACGGAGAACGTATTCTGGGTCTGGGCGACTTGGGCGCATGCGGGATGGGCATCCCTGTGGGCAAACTCGCGCTCTACACCGCGCTCGGAGGCATCAAGCCGCATCAGTGTCTGCCCATCACTATCGACGTGGGTACGAACACCCAGTCGATGCTGGACGACCCGCTGTACATCGGGCTCCGGCAGCGGCGCGTGCGCGGCCCCGACTACGACGAGCTGCTCGACGAGTTCATGCGCGCCGTCGTGCGCCGCTACGGGCAGAACTGTCTCGTGCAGTTCGAGGACTTCGGGAACGCTAACGCTTTTAGGCTCCTCGAGAAGTACAGGAACAAGTACTGCACTTTCAACGACGACATCCAGGGGACGGCGGCCGTGGCGGTGGCGGGACTACTCGCCAGTCTCAGACTCACACAGAAGAGGCTGTCCGACAACGTCATCGTCTTCCAGGGAGCCGGAGAGGCCGCTTTGGGTATCGCGGAGCTGTGCGTTATGGCCATGAAGGGCGAGGGCACGCCGGAGCAGGAGGCGAGGTGCCGCATCTGGATGGTGGACTCGAAGGGCCTCATCGTCAAGAACAGACCGGAGGGAGGGCTTAACGTTCACAAGGAGAGGTTCGCTCAGGACCACGCGCCCGTCAGGACCTTGGCAGAAGTTGTGGAAGTGGCCAGACCATCAGTGCTTATTGGAGCGGCCGCCATCGGTGGTGCTTTCACTCCTGAGATATTGAGGAAGATGGCAAACTTCAACGAGAAGCCAGTCATCTTCGCTCTCTCGAACCCCACCAGCAAGGCGGAGTGTACCGCTGAAGAAGCCTACAGTAACACCGACGACCGTGCTATATTCGCGTCGGGGTCACCGTTCCCGGAGTACCGCAGTAAGTCGGGCGCGTTGTTCCGCCCGGGACAAGGCAACAACTCGTACATCTTCCCGGGACTCGCGCTCGGCATCATCTGCGCCGGGATACTGGACATCTCGGACGACTTCATGCTACTCGCCGCCGAGGCTTTAGCGGAAATTGTGTCGGATGATGATCTCGCATACGGAAGCTTGTACCCGCCTCTGCACATGATAAAGGATTGTTCCGTTAAGATCGCGAAGAAGATTGTCGAACACGCCTACAATACAGGCAAGGCGTCGGTGCAGCCGCAGCCGCTCGACACGGAGGAGTTCATCCGCGCGCAGATGTACAGCGTGGAGTACGGCGCCGCGCTGCCGCCCGCCTACCCGTGGCCGGACAACCAGCCGCGGGTCGCGATCATCTAA

Protein

MEYLSRTMNGNSGKCQVNGTVRDIREMKRSESAMSPAPPAHCNKTGVPFSAVKQSQATSGGKCTYSEMERDRIGLWGSGDGQPTSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTNTQSMLDDPLYIGLRQRRVRGPDYDELLDEFMRAVVRRYGQNCLVQFEDFGNANAFRLLEKYRNKYCTFNDDIQGTAAVAVAGLLASLRLTQKRLSDNVIVFQGAGEAALGIAELCVMAMKGEGTPEQEARCRIWMVDSKGLIVKNRPEGGLNVHKERFAQDHAPVRTLAEVVEVARPSVLIGAAAIGGAFTPEILRKMANFNEKPVIFALSNPTSKAECTAEEAYSNTDDRAIFASGSPFPEYRSKSGALFRPGQGNNSYIFPGLALGIICAGILDISDDFMLLAAEALAEIVSDDDLAYGSLYPPLHMIKDCSVKIAKKIVEHAYNTGKASVQPQPLDTEEFIRAQMYSVEYGAALPPAYPWPDNQPRVAII

Similarity

Belongs to the malic enzymes family.

Uniprot

Q1HPM5   H9JA74   S4PXL2   A0A194Q305   A0A2W1BVZ1   A0A212F341   + More
A0A2H1VG83   A0A194R521   A0A2A4IX16   D6WC31   A0A1B6CP21   A0A1B6CTZ5   A0A1B6BX03   A0A1B6DMS8   A0A1W4WN34   A0A1B6ELV0   A0A232EUS8   L7WRS4   V5G0U1   K7IN29   A0A0C9RBH8   A0A0C9QUA2   A0A1B6G2L6   A0A2J7Q034   V9IDL3   V9IBE4   A0A1B6EH99   A0A088ATR6   A0A1B6D0Y8   A0A1B6CZ99   A0A336KJT6   E2AMD6   A0A026VWQ8   A0A1B6CDE8   A0A154P9U9   A0A151XCT1   A0A195DYI1   A0A0P6DBL3   A0A151IFH8   Q178T5   A0A0P5ETE2   A0A0P5N253   A0A0N7ZUI9   A0A0P4XM76   A0A0P5BNM0   A0A0P6D198   A0A0P5DM95   A0A0P6E0Y6   F4WZL9   A0A0P5BWR5   A0A0P5AKK8   A0A0N8AC63   A0A0P5YQT9   A0A1Q3FP88   A0A1Q3FPH9   A0A195B7P4   A0A0P4WQB3   A0A0P5SBM6   A0A1S4FBJ4   A0A0P4YGZ3   A0A0P6H949   A0A0P4WV08   A0A0P4WKD6   A0A0N7ZE97   A0A1S4FBM2   A0A195FFD0   A0A0P5E699   A0A0P5DUI5   U5EW70   A0A158NGS1   A0A0P4Z3D1   A0A310S7K1   E9GLD2   A0A2J7Q035   A0A0P6G7M9   B0WYF3   E0VKN6   A0A1L8E8N4   A0A1L8E8M1   A0A1L8E887   A0A0P4XQE0   A0A1L8E890   Q1HQN2   A0A1L8E8L5   A0A0P4YPF9   A0A1L8E886   A0A1Y1LIQ6   A0A1I8PRL1   A0A1I8PRQ3   A0A0P4VHP2   J9JUU8   A0A0P6B1C0   U4U1N0   A0A2M4CGY2   T1DPT6   A0A1B6DG24   A0A2M3ZFJ4   A0A1B6DTX1   F5HJQ2   A0A182HIC1  

Pubmed

19121390    23622113    26354079    28756777    22118469    18362917    + More
19820115    28648823    23326229    20075255    20798317    24508170    30249741    17510324    21719571    21347285    21292972    20566863    17204158    28004739    27129103    23537049    12364791    14747013    17210077   

EMBL

DQ443377    ABF51466.1    BABH01009001    BABH01009002    BABH01009003    GAIX01004843    + More
JAA87717.1    KQ459579    KPI99384.1    KZ149939    PZC76970.1    AGBW02010641    OWR48133.1    ODYU01002375    SOQ39791.1    KQ460685    KPJ12903.1    NWSH01005759    PCG63968.1    KQ971310    EEZ99126.1    GEDC01022082    GEDC01013651    JAS15216.1    JAS23647.1    GEDC01020404    GEDC01002355    JAS16894.1    JAS34943.1    GEDC01031481    JAS05817.1    GEDC01010314    JAS26984.1    GECZ01030907    JAS38862.1    NNAY01002100    OXU22086.1    KC118983    AGC84405.1    GALX01004841    JAB63625.1    GBYB01004236    JAG74003.1    GBYB01004237    JAG74004.1    GECZ01013091    JAS56678.1    NEVH01020327    PNF21941.1    JR038797    AEY58419.1    JR038798    AEY58420.1    GEDC01000017    JAS37281.1    GEDC01017964    JAS19334.1    GEDC01018570    JAS18728.1    UFQS01000467    UFQT01000467    SSX04242.1    SSX24607.1    GL440813    EFN65360.1    KK107681    QOIP01000006    EZA48085.1    RLU21546.1    GEDC01025824    JAS11474.1    KQ434851    KZC08613.1    KQ982294    KYQ58184.1    KQ980107    KYN17664.1    GDIQ01081394    JAN13343.1    KQ977793    KYM99669.1    CH477359    EAT42717.1    GDIQ01268247    GDIQ01084393    JAJ83477.1    GDIQ01148090    JAL03636.1    GDIP01211225    GDIP01211224    JAJ12177.1    GDIP01239231    GDIP01239230    JAI84171.1    GDIP01182970    JAJ40432.1    GDIQ01084394    JAN10343.1    GDIP01252066    GDIP01252065    GDIP01252064    GDIP01251068    GDIP01251067    GDIP01251066    GDIP01157682    GDIP01157681    GDIP01150935    GDIP01135438    GDIP01135437    GDIP01135436    GDIP01115092    GDIP01114991    GDIP01113393    GDIP01113392    GDIP01047049    GDIP01047007    JAJ65720.1    GDIQ01084392    JAN10345.1    GL888480    EGI60294.1    GDIP01182971    JAJ40431.1    GDIP01197987    JAJ25415.1    GDIP01231570    GDIP01162831    GDIP01161834    GDIP01161833    JAJ61569.1    GDIP01116329    GDIP01113394    GDIP01054550    GDIP01054549    GDIP01048547    GDIP01048546    JAM49166.1    GFDL01005635    JAV29410.1    GFDL01005611    JAV29434.1    KQ976574    KYM80267.1    GDIP01254156    JAI69245.1    GDIP01254817    GDIP01254816    GDIP01252013    GDIP01230317    GDIP01230272    GDIP01219021    GDIP01219020    GDIP01213924    GDIP01197073    GDIP01186837    GDIP01185621    GDIP01175089    GDIP01162830    GDIP01161832    GDIP01143431    GDIP01143430    GDIP01142330    GDIP01142329    GDIP01142328    GDIP01141284    GDIP01141283    GDIP01141282    GDIP01139184    GDIP01139183    GDIP01139182    GDIP01131741    GDIP01131740    GDIP01131739    GDIP01128626    GDIP01127335    GDIP01127334    GDIP01127333    GDIP01125950    GDIP01125949    GDIP01125948    GDIP01125947    GDIP01099085    GDIP01099084    GDIP01097700    GDIP01096446    GDIP01096445    GDIP01096444    GDIP01076391    GDIP01074950    GDIP01072485    JAL61385.1    GDIP01230318    JAI93083.1    GDIQ01022959    JAN71778.1    GDIP01254815    JAI68586.1    GDIP01254155    JAI69246.1    GDIP01253961    GDIP01253960    GDIP01231569    JAI69440.1    KQ981625    KYN39093.1    GDIP01150989    JAJ72413.1    GDIP01150987    GDIP01150934    JAJ72415.1    GANO01001561    JAB58310.1    ADTU01015189    GDIP01219019    JAJ04383.1    KQ765373    OAD53959.1    GL732551    EFX79712.1    PNF21942.1    GDIQ01037401    JAN57336.1    DS232187    EDS37030.1    DS235250    EEB13942.1    GFDG01003843    JAV14956.1    GFDG01003840    JAV14959.1    GFDG01003841    JAV14958.1    GDIP01239229    JAI84172.1    GFDG01003842    JAV14957.1    DQ440412    ABF18445.1    GFDG01003844    JAV14955.1    GDIP01226524    JAI96877.1    GFDG01003839    JAV14960.1    GEZM01054602    JAV73532.1    GDKW01002495    JAI54100.1    ABLF02026861    GDIP01021514    JAM82201.1    KB631801    ERL86223.1    GGFL01000395    MBW64573.1    GAMD01001655    JAA99935.1    GEDC01012664    JAS24634.1    GGFM01006487    MBW27238.1    GEDC01008171    JAS29127.1    AAAB01008846    EGK96513.1    APCN01003927   

Proteomes

UP000005204    UP000053268    UP000007151    UP000053240    UP000218220    UP000007266    + More
UP000192223    UP000215335    UP000002358    UP000235965    UP000005203    UP000000311    UP000053097    UP000279307    UP000076502    UP000075809    UP000078492    UP000078542    UP000008820    UP000007755    UP000078540    UP000078541    UP000005205    UP000000305    UP000002320    UP000009046    UP000095300    UP000007819    UP000030742    UP000007062    UP000075840   

PRIDE

Q1HPM5    H9JA74   

Pfam

PF00390   malic        + More
PF03949   Malic_M
PF05276   SH3BP5

Interpro

IPR037062   Malic_N_dom_sf        + More
IPR001891   Malic_OxRdtase       
IPR012302   Malic_NAD-bd       
IPR015884   Malic_enzyme_CS       
IPR012301   Malic_N_dom       
IPR036291   NAD(P)-bd_dom_sf       
IPR007940   SH3BP5       

SUPFAM

SSF51735   SSF51735       

Gene 3D

3.40.50.10380    

ProteinModelPortal

Q1HPM5   H9JA74   S4PXL2   A0A194Q305   A0A2W1BVZ1   A0A212F341   + More
A0A2H1VG83   A0A194R521   A0A2A4IX16   D6WC31   A0A1B6CP21   A0A1B6CTZ5   A0A1B6BX03   A0A1B6DMS8   A0A1W4WN34   A0A1B6ELV0   A0A232EUS8   L7WRS4   V5G0U1   K7IN29   A0A0C9RBH8   A0A0C9QUA2   A0A1B6G2L6   A0A2J7Q034   V9IDL3   V9IBE4   A0A1B6EH99   A0A088ATR6   A0A1B6D0Y8   A0A1B6CZ99   A0A336KJT6   E2AMD6   A0A026VWQ8   A0A1B6CDE8   A0A154P9U9   A0A151XCT1   A0A195DYI1   A0A0P6DBL3   A0A151IFH8   Q178T5   A0A0P5ETE2   A0A0P5N253   A0A0N7ZUI9   A0A0P4XM76   A0A0P5BNM0   A0A0P6D198   A0A0P5DM95   A0A0P6E0Y6   F4WZL9   A0A0P5BWR5   A0A0P5AKK8   A0A0N8AC63   A0A0P5YQT9   A0A1Q3FP88   A0A1Q3FPH9   A0A195B7P4   A0A0P4WQB3   A0A0P5SBM6   A0A1S4FBJ4   A0A0P4YGZ3   A0A0P6H949   A0A0P4WV08   A0A0P4WKD6   A0A0N7ZE97   A0A1S4FBM2   A0A195FFD0   A0A0P5E699   A0A0P5DUI5   U5EW70   A0A158NGS1   A0A0P4Z3D1   A0A310S7K1   E9GLD2   A0A2J7Q035   A0A0P6G7M9   B0WYF3   E0VKN6   A0A1L8E8N4   A0A1L8E8M1   A0A1L8E887   A0A0P4XQE0   A0A1L8E890   Q1HQN2   A0A1L8E8L5   A0A0P4YPF9   A0A1L8E886   A0A1Y1LIQ6   A0A1I8PRL1   A0A1I8PRQ3   A0A0P4VHP2   J9JUU8   A0A0P6B1C0   U4U1N0   A0A2M4CGY2   T1DPT6   A0A1B6DG24   A0A2M3ZFJ4   A0A1B6DTX1   F5HJQ2   A0A182HIC1  

PDB

1GQ2     E-value=0,     Score=1734

KEGG

100101182    K00029 malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] | (RefSeq) malate de

PATHWAY

00620    Pyruvate metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01200    Carbon metabolism - Bombyx mori (domestic silkworm)

GO

GO:0046872   GO:0051287   GO:0004471   GO:0006090   GO:0006108   GO:0005739   GO:0004470   GO:0004473   GO:0016021   GO:0035556   GO:0006432   GO:0000287   GO:0003723   GO:0006270   GO:0042555   GO:0048384   GO:0055114  

Length:

645

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.02656

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00719

outside

1  -  645

 

 

Pi

275.444784

Theta

192.679226

Tajima's D

1.097855

CLR

0.537979

CSRT

0.68341582920854

Interpretation

Uncertain