Gene

KWMTBOMO03301  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA006424

Annotation

phenylalanyl-tRNA_synthetase_beta_subunit_[Bombyx_mori]

Location

Bomo_Chr6(-):3816689-3829451      View in EpiBrowser

Full name

Phenylalanine--tRNA ligase beta subunit      

Alternative Name

Phenylalanyl-tRNA synthetase beta subunit

Location in the cell

Cytoplasmic   Reliability : 2.538

CDS

ATGCCCACAATTTCTTTAAAGCGCGATGCGCTTTTCGCCGCACTCGGTTCTACATACACTGATGAAGAATTTCAAGACCTATGTTTCAAATTTGGTTTAGAGCTTGATGAAGTTACTACGGAGAAACAAATGTTAATTAAAGAACAAGGTGACCAAGCAGATGCTGAATTATCTGATGAGATCCTCTACAGAATAGACATCCCAGCCAATAGATATGACTTATTGTGCCTCGAAGGACTTGTTGATGGTCTATTAGTGTTCCAGGGGAAGAAACCTCCACCTCAGTACAAAGTGAAAAAATATGAAGACTGTAACTCTTTACACCTAACGATGGCCACAGCACAAATAAGACCCTATGCTGTAGCAGCTGTACTTAGAGGCATTACTTTTACAAAGGAATCTTATGATAGTTTCATTGATCTACAGGACAAACTGCACCAAAACATTTGCAGGAAAAGGACTTTAGTGGCTATAGGAACACATGATCTGGACACTATACATGGTCCATTCATCTATGATGCATTGCCTCCAAATGAGATTAAGTTCAAAGCTCTTAATCAGCCAAAAGAATTAACTGCACCTGAATTAATGGAGTTATATTCGAATCACGCCCAATTAAAACAATATTTAGGAATCATAAAGGAGAGCCCAGTGTATCCAATCATCAAAGATAAAAACGGAGTGATATTGTCTATGCCTCCAATAATTAATAGTGATCATTCTAAAATTACACTAAATACAAAGAATGTATTCATAGAATGCACTGCAACTGATTTAACTAAGGCTATTGTAGTTCTGGACACGGTGGTCAGCATGTTCTCGAAATACTGCACGAGCGAGTATGAAGTACAACAATGTAAAGTTTTCTCTCCTGATGGAACTTACGAATTGTATCCCAAGCTTCAATATAGAGAAGAACTTATTAATGTTGATAAAGCCAACAACTATATTGGGATCAGTGAAGAAGGTGATAAGCTAGCGTCGTTGCTGTCCCGGATGTGTCTCCAGACCGCGCACGAGGGCTCCGTGCTGCGCGTGCGAGTCCCCCCCACGAGGCACGACGTCATTCACGCTTGCGACCTCTACGAAGACATCGCTATAGCATACGGGTACAACCGCATAGCGCGGCGCCCCGCCCGCGCCGTGACGTCAGGCGGACAGGACCCCGCCAACAAACTCACGGAGCAGCTGCGGAACGAGTGCGCCCGCGCCGGCTACACTGAAGCGCTCACCTTCACACTTTGCTCCCGTGAAGACGTATCTACGAAATTGGGTGTTAAAATCGAAGATGTACCGGCCGCCCACATCTCCAATCCCAAGACCCTGGAGTTCCAAGTAGTCCGAACGTTGTTACTACCCGGGCTGCTGAAAACCATTGCTGCAAACAAAAAAATGCCTTTACCCTTGAAACTCTTCGAGATCAGCGATGTTGTGCTTCTAGATGAGAATGCCGAAAGCGGGGCACGCAACGTGCGGCGCGCGTGCGGCGTGCACTGCGGGCGCGCGGCCGGCTTCCAGCACGTGCACGGCCTGCTCGACCGGCTCATGGCGCAGCTGCGGGTGCGGCACCGCGACCAGTACGCGCTGCGACCTGCGCAAGATCCCGCTTATTTCCCTGGTCGCTGCGCTGAAGTTGTACTTCAAGGAAAAGTAATCGGAAAGATTGGAGTCATCCACCCGAATGTGCTGACAGCATTCGAGCTTACGAATCCGTGCTCTGCTGTTGAAATAGATATTGAACCATTCGTGTAA

Protein

MPTISLKRDALFAALGSTYTDEEFQDLCFKFGLELDEVTTEKQMLIKEQGDQADAELSDEILYRIDIPANRYDLLCLEGLVDGLLVFQGKKPPPQYKVKKYEDCNSLHLTMATAQIRPYAVAAVLRGITFTKESYDSFIDLQDKLHQNICRKRTLVAIGTHDLDTIHGPFIYDALPPNEIKFKALNQPKELTAPELMELYSNHAQLKQYLGIIKESPVYPIIKDKNGVILSMPPIINSDHSKITLNTKNVFIECTATDLTKAIVVLDTVVSMFSKYCTSEYEVQQCKVFSPDGTYELYPKLQYREELINVDKANNYIGISEEGDKLASLLSRMCLQTAHEGSVLRVRVPPTRHDVIHACDLYEDIAIAYGYNRIARRPARAVTSGGQDPANKLTEQLRNECARAGYTEALTFTLCSREDVSTKLGVKIEDVPAAHISNPKTLEFQVVRTLLLPGLLKTIAANKKMPLPLKLFEISDVVLLDENAESGARNVRRACGVHCGRAAGFQHVHGLLDRLMAQLRVRHRDQYALRPAQDPAYFPGRCAEVVLQGKVIGKIGVIHPNVLTAFELTNPCSAVEIDIEPFV

Catalytic Activity

ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)

Subunit

Tetramer of two alpha and two beta subunits.

Similarity

Belongs to the GST superfamily.
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
Belongs to the EF-1-beta/EF-1-delta family.

Keywords

Aminoacyl-tRNA synthetase   ATP-binding   Complete proteome   Cytoplasm   Ligase   Nucleotide-binding   Protein biosynthesis   Reference proteome  

Feature

chain  Phenylalanine--tRNA ligase beta subunit

Uniprot

E0D4V7   A0A2W1BWD3   A0A2H1X2X4   A0A212F320   S4PK77   A0A0N1PGH5   + More
Q9VCA5   B4HGK9   A0A0T6B0S1   A0A1Y1L114   B4PKZ2   A0A2J7PZJ6   B3P768   A0A1W4US24   B3M0J6   A0A2P8XNY2   B4M5Q8   A0A2J7PZJ4   B4NAF8   B4K7G4   U5EXX1   Q298I1   A0A139WN72   A0A1W4XEQ4   A0A3B0K3Y3   B4G3Z1   B4QT31   A0A0L0CRD1   A0A084W1R2   A0A182JMM9   W8BG13   A0A1B6M1Z7   A0A0A1XCZ9   A0A182NSK1   A0A1L8DFL7   A0A1B6EWG0   Q7QAV9   A0A182HZ48   A0A0K8VJ14   A0A182URB8   A0A182KXB4   A0A034W5K7   A0A182JYD1   A0A182WVZ0   A0A1I8MRV2   B4JH33   A0A182QFA5   A0A182P097   A0A182TSZ9   A0A1B6DE20   T1PJJ9   W5J571   A0A1I8Q7C3   A0A023EU76   A0A182GPY4   A0A182R8A1   A0A2M4A5N1   A0A2M4A5P1   A0A182VS39   A0A2M4BI26   A0A1B0CSF9   A0A2M4BIC9   A0A2M3YZU6   A0A182FL19   A0A026WAP6   A0A2M3Z001   A0A2M4A5W5   Q17C95   A0A1S4F853   A0A1Q3F447   A0A182YLK9   N6U1A5   A0A023EVD9   A0A182M295   J9K9N3   E2BE89   A0A1J1HYI0   A0A2S2R343   A0A3B4ZPN7   E2A2Q0   A0A1A9XG67   A0A1B0BQ40   A0A1A9WY64   A0A2M4BEX5   A0A232EZT4   A0A3P8RQ16   E9GZV7   A0A2J7PZK5   H2LYY4   A0A3P9IPY4   A0A1A9UZ08   A0A3B3HKC4   H2LZ90   Q5EBG3   A0A0L7RD93   A0A3B4U448   A0A3P9GY17   A0A3B4ZCP1   F7DMT3   Q7T0M8  

EC Number

6.1.1.20

Pubmed

19121390    28756777    22118469    23622113    26354079    10731132    + More
12537572    12537569    25427601    17994087    28004739    17550304    29403074    15632085    18362917    19820115    26108605    24438588    24495485    25830018    12364791    14747013    17210077    20966253    25348373    25315136    20920257    23761445    24945155    26483478    24508170    17510324    25244985    23537049    20798317    28648823    21292972    17554307    20431018   

EMBL

BABH01008989    BABH01008990    BABH01008991    AB546862    BAJ14787.1    KZ149939    + More
PZC76976.1    ODYU01013030    SOQ59665.1    AGBW02010641    OWR48124.1    GAIX01004655    JAA87905.1    KQ460650    KPJ13070.1    AE014297    AY052086    CH480815    EDW43462.1    LJIG01016334    KRT80914.1    GEZM01067984    JAV67284.1    CM000160    EDW98977.1    NEVH01020334    PNF21755.1    CH954182    EDV53888.1    CH902617    EDV44243.1    PYGN01001634    PSN33654.1    CH940652    EDW58984.1    PNF21751.1    CH964232    EDW80772.1    CH933806    EDW14288.1    GANO01000702    JAB59169.1    CM000070    EAL27974.1    KQ971312    KYB29382.1    OUUW01000007    SPP82680.1    CH479179    EDW24402.1    CM000364    EDX14195.1    JRES01000007    KNC34920.1    ATLV01019415    KE525269    KFB44156.1    GAMC01006320    JAC00236.1    GEBQ01010008    JAT29969.1    GBXI01005949    JAD08343.1    GFDF01008848    JAV05236.1    GECZ01027521    JAS42248.1    AAAB01008888    EAA08937.2    EGK97049.1    APCN01005482    GDHF01013764    JAI38550.1    GAKP01008096    JAC50856.1    CH916369    EDV92724.1    AXCN02000234    GEDC01013416    JAS23882.1    KA648108    AFP62737.1    ADMH02002130    ETN58558.1    GAPW01000643    JAC12955.1    JXUM01015409    KQ560429    KXJ82448.1    GGFK01002701    MBW36022.1    GGFK01002711    MBW36032.1    GGFJ01003569    MBW52710.1    AJWK01026035    GGFJ01003570    MBW52711.1    GGFM01001048    MBW21799.1    KK107295    EZA53110.1    GGFM01001075    MBW21826.1    GGFK01002799    MBW36120.1    CH477310    EAT43980.1    GFDL01012720    JAV22325.1    APGK01043586    KB741015    ENN75330.1    GAPW01000641    JAC12957.1    AXCM01000846    ABLF02014205    ABLF02014206    GL447768    EFN85934.1    CVRI01000026    CRK92388.1    GGMS01015182    MBY84385.1    GL436195    EFN72288.1    JXJN01018373    GGFJ01002453    MBW51594.1    NNAY01001458    OXU23902.1    GL732579    EFX74882.1    PNF21752.1    BC089642    CR942340    AAH89642.1    CAJ83855.1    KQ414613    KOC68937.1    AAMC01060088    AAMC01060089    AAMC01060090    AAMC01060091    AAMC01060092    BC056121    AAH56121.1   

Proteomes

UP000005204    UP000007151    UP000053240    UP000000803    UP000001292    UP000002282    + More
UP000235965    UP000008711    UP000192221    UP000007801    UP000245037    UP000008792    UP000007798    UP000009192    UP000001819    UP000007266    UP000192223    UP000268350    UP000008744    UP000000304    UP000037069    UP000030765    UP000075880    UP000075884    UP000007062    UP000075840    UP000075903    UP000075882    UP000075881    UP000076407    UP000095301    UP000001070    UP000075886    UP000075885    UP000075902    UP000000673    UP000095300    UP000069940    UP000249989    UP000075900    UP000075920    UP000092461    UP000069272    UP000053097    UP000008820    UP000076408    UP000019118    UP000075883    UP000007819    UP000008237    UP000183832    UP000261400    UP000000311    UP000092443    UP000092460    UP000091820    UP000215335    UP000265080    UP000000305    UP000001038    UP000265200    UP000078200    UP000053825    UP000261420    UP000261360    UP000008143   

PRIDE

E0D4V7    Q9VCA5   

Pfam

PF17759   tRNA_synthFbeta        + More
PF03483   B3_4
PF18262   PhetRS_B1
PF03484   B5
PF00043   GST_C
PF02798   GST_N
PF10018   Med4
PF07544   Med9
PF00736   EF1_GNE
PF10587   EF-1_beta_acid

Interpro

IPR005147   tRNA_synthase_B5-dom        + More
IPR004531   Phe-tRNA-synth_IIc_bsu_arc       
IPR040659   PhetRS_B1       
IPR005146   B3/B4_tRNA-bd       
IPR041616   PheRS_beta_core       
IPR009061   DNA-bd_dom_put_sf       
IPR020825   Phe-tRNA_synthase_B3/B4       
IPR036249   Thioredoxin-like_sf       
IPR036282   Glutathione-S-Trfase_C_sf       
IPR004046   GST_C       
IPR010987   Glutathione-S-Trfase_C-like       
IPR040079   Glutathione_S-Trfase       
IPR004045   Glutathione_S-Trfase_N       
IPR011425   Med9       
IPR019258   Mediator_Med4       
IPR018940   EF-1_beta_acid_region_euk       
IPR036219   eEF-1beta-like_sf       
IPR014038   EF1B_bsu/dsu_GNE       
IPR001326   Transl_elong_EF1B_B/D_CS       
IPR014717   Transl_elong_EF1B/ribosomal_S6       

SUPFAM

SSF46955   SSF46955        + More
SSF52833   SSF52833       
SSF47616   SSF47616       
SSF54984   SSF54984       

Gene 3D

3.50.40.10     3.30.70.60    

CDD

cd00769  PheRS_beta_core
cd00292  EF1B

ProteinModelPortal

E0D4V7   A0A2W1BWD3   A0A2H1X2X4   A0A212F320   S4PK77   A0A0N1PGH5   + More
Q9VCA5   B4HGK9   A0A0T6B0S1   A0A1Y1L114   B4PKZ2   A0A2J7PZJ6   B3P768   A0A1W4US24   B3M0J6   A0A2P8XNY2   B4M5Q8   A0A2J7PZJ4   B4NAF8   B4K7G4   U5EXX1   Q298I1   A0A139WN72   A0A1W4XEQ4   A0A3B0K3Y3   B4G3Z1   B4QT31   A0A0L0CRD1   A0A084W1R2   A0A182JMM9   W8BG13   A0A1B6M1Z7   A0A0A1XCZ9   A0A182NSK1   A0A1L8DFL7   A0A1B6EWG0   Q7QAV9   A0A182HZ48   A0A0K8VJ14   A0A182URB8   A0A182KXB4   A0A034W5K7   A0A182JYD1   A0A182WVZ0   A0A1I8MRV2   B4JH33   A0A182QFA5   A0A182P097   A0A182TSZ9   A0A1B6DE20   T1PJJ9   W5J571   A0A1I8Q7C3   A0A023EU76   A0A182GPY4   A0A182R8A1   A0A2M4A5N1   A0A2M4A5P1   A0A182VS39   A0A2M4BI26   A0A1B0CSF9   A0A2M4BIC9   A0A2M3YZU6   A0A182FL19   A0A026WAP6   A0A2M3Z001   A0A2M4A5W5   Q17C95   A0A1S4F853   A0A1Q3F447   A0A182YLK9   N6U1A5   A0A023EVD9   A0A182M295   J9K9N3   E2BE89   A0A1J1HYI0   A0A2S2R343   A0A3B4ZPN7   E2A2Q0   A0A1A9XG67   A0A1B0BQ40   A0A1A9WY64   A0A2M4BEX5   A0A232EZT4   A0A3P8RQ16   E9GZV7   A0A2J7PZK5   H2LYY4   A0A3P9IPY4   A0A1A9UZ08   A0A3B3HKC4   H2LZ90   Q5EBG3   A0A0L7RD93   A0A3B4U448   A0A3P9GY17   A0A3B4ZCP1   F7DMT3   Q7T0M8  

PDB

3L4G     E-value=0,     Score=1712

KEGG

100499569    K01890 phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] | (RefSeq) FRSB; phenylalanyl-tRNA synt

PATHWAY

00970    Aminoacyl-tRNA biosynthesis - Bombyx mori (domestic silkworm)

GO

GO:0006432   GO:0005524   GO:0003723   GO:0005737   GO:0004826   GO:0000287   GO:0002161   GO:0009328   GO:0003712   GO:0016592   GO:0006357   GO:0005853   GO:0003746   GO:0006414   GO:0005829   GO:0005085   GO:0000166   GO:0006270   GO:0042555   GO:0048384  

Subcellular location

Cytoplasm  

Length:

583

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0216899999999999

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00192

outside

1  -  583

 

 

Pi

138.271601

Theta

150.932417

Tajima's D

-0.905174

CLR

1.127941

CSRT

0.157542122893855

Interpretation

Uncertain