Gene

KWMTBOMO03266

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr6(-):2647938-2652526      View in EpiBrowser

Full name

RNA-directed DNA polymerase from mobile element jockey      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 2.13

CDS

ATGCCTGCCGCTCCCGCGTCGCCTATACTAGTGGGTAAAACTGCTGCGTCGTCCGCCGTGGTCGCCGCTCCCCTGGCGCGATCATCCGCGGGTTCAGTAGGGTCCGACGGACATCCTGCATCTGCCCGTAGGTCGCCTGCTCCCGAGCCTGCTGCCTCCTCGTCCTCCGACTCTGACTCGGACATGGAGGTCGACCTCGCCGCCGCCTCATCGACGGATGGATTCACCCTGGTACAAAAGGGTAAGAAGCGCGCTGCGGAGTCCCGAGCTCCCGCGGCCGCTAAAATTAGTAAAGCCGCGAACGCGTCGCGCCCTCGCCCTCCGACTCCCGTCGCTCCCCCTGCCCGTGCCACACCGTCGCCGCGTCCAGTGGCACAAAATAAAACTCAGACCCCTCCCCCGGTAATCCTTCAAGAGAAGGCAGCTTGGGACCGAGTTTCCCTGGCCCTTCAGGCCAAAAAAATTAATTTTATCAGCGCCCGTAACCTCGCGAACGGGATTCAAATTAAGGTAACGACACCCGACGACCATAGGGCCCTCTCAAGCTACCTCCGAAAGGAGCGTATAAGTTTCCACACTTATACGCTTCAGGAGGAGCGTGAACTTCGCGCGGTCATACGCGGCATCCCAAAGGAATTAGATGCCGATCTCGTCAAGGCCGACCTTCTAGAACAAGGTCTGCCGGAGACCCTGCTTAAGCCCGCGCGCCGCGACCCTAAAATCGCGAACTACAACATGGTTAGGAACGACAGGCTCACTGCTCGTGGTGGTGGTACCGTCATTTACTATAGAAGAGCCCTGCATTGCGTCCCACTCGACCCCCCCGCGCTTTCTAACATCGAAGCATCAGTATGCCGAATCTCACTGACTGGACACGCGCCGATCGTTATCGCGTCCGTTTATCTTCCACCGGATAAAATTGTTCTAAGTAGTGATATTGAGGCGCTGCTCGGCATGGGAAGCTCTGTCATTCTGGCGGGTGACCTAAATTGTAAACACGTCAGGTGGAACTCTCACACCTCAACCCCTAATGGCAGGCGCCTCGACGCGTTAGTCGATGATCTCGCCTTCGATATCGTCGCTCCGCTGACCCCGACTCACTACCCGCTAAATATCGCGCATCGCCCGGATATACTCGACATAGCGTTATTAAAAAACGTAACTCGGCGCTTACATTCGATTGAAGTAGTTTCAGAGTTAGATTCAGACCATCGTCCCGTCATTATGAAGCTCGGTCGCGCTCCCGATTCCGTTCCCATCACGAGGACTGTGGTGGATTGGCACACGCTGGGCATCAGCCTGGCTGAATCTGATCCACCATCGCTTCCGTTTAGTCTGGACTCTATCCCGTCTCCTCAGGATACCGCTGAAGCCATAGACATCGTAACGTCACACATCACCTCGACATTAGATAGGTCATCGAAGCAAGTTGTAGCGGAGGACTTCCTTCACCGCTTCAAATTGTCCGACGATATTAGGGAACTCCTTAGAGCTAAGAACGCCTCGATCCGTGCGTACGATAGCTCGTACTCTCAAATCGGATACGGTAGTAACTATGCCCCCCTCGTAGGCCCCTCAGGCCGACTCGCGGCGTTCGATGATGACGAAAAAGCAGAGCTGCTGGCCGATACATTGCAAGCCCAGTGCATGCCCAGCATTCAATCCGCGGACCCTGTTCATGTAGAATTAGTAGACAGTGAGGTAGAACGCAGAGCCTCCTTGCCACCCTTGGACGCGTTACCGCCCGTCACCTCAATGGAAGTTAAAGACCTGATCAAAGACCTACGTCCTCGCAAGGCTCCCGGTTCCGACGGTATATCTAACCGCGTTATTAAACTTTTACCCGTCCAACTCATCGTGATGTTGGCATCTATTTTCAATGCCACTATGGCTAACTGTATCTTTCCCACGGTATGGAAAGAAGCGGACGTTATCGGCATACACAAACCCGATAAACCAAAAAACAATCCGACCAGTTACCGCCCGATTAGCCTCCTCATGTCTCTAGGCAAACTGTATGAGCGTCTGCTCTACAAACGCCTCAGAGACTTCGTCTCATCCAAGGGCATTCTCATCGATGAACAATTCGGATTCCGTGCAAATCACTCATGCGTACAACAGGTGCACCGCCTCACGGAGCACATTCTTGTGGGACTTAATCGACCAAAACCGTTATACACGGGAGCTCTCTTCTTCGACGTCGCAAAAGCGTTCGACAAAGTCTGGCAAAACGGTTTGATTTTCAAACTATTCAACATGGGCGTGCCGGATAGTCTCGTGCTCATCATACGGGACTTCTTGTCGAACCGCTCTTTTCGATATCGAGTAGAGGGAACCCGCTCCTCCCCGCGACCACTCACGGCTGGAGTGCCGCAAGGCTCCGTTCTCTCACCGCTCCTATTTAGTTTATTTATTAATGATATTCCCCGGTCGCCGCCGACCCAGCTAGCCTTATTCGCTGACGACACAACCGTTTACTACTCAAGTAGAAACAAGTCCCTAATCGCGAGTAAACTCCAGAGCGCAGCGTTAGCCCTCGGACAGTGGTTCCGAAAATGGCGCATAGACATCAACCCGGCGAAAAGCACAGCAGTGTTATTTCAAAGGGGAAACTCACCGCTTATTTCCTCCCGCATTAGGAGGAGAAATATCACTCCCCCGATCACCCTCTTCGGCCAACCTATACCCTGGGTCAGGAAGGTTAAGTACCTGGGAGTCACCCTGGATGCATCCATGACATTCCGCCCACACATAAAAACAGTCCGCGACCGTGCCGCATTCATTCTCGGCAGACTCTATCCCATGATCTGTAAGCGGAGTAAAATGTCCCTTCGGAACAAGGTGACACTTTACAAAACTTGCATAAGGCCCATCATGACTTATGCGAGTGTGGTGTTCGCTCACGCGGCCCGCACACACATAGACACCCTCCAATCCCTACAATCCCGCTTTTGCAGGTTAGCCGTCGGGGCTCCGTGGTTCGTGAGGAACGTTGACCTACACGACGACCTGGGCCTTGAATCAATCCAGAAATACATGAAGTCAGCGTCGGAACGGTACTTCGATAAGGCTATGCGTCATGATAATCGCCTTATCGTTGCCGCCGCTGACTACTCACCGAATCCTGATCATGCAGGAGCCAGTCACCGTCGACGCCCTAGACACGTCCTTACGGATCCATCAGATCCAATAACCTTTGCATTAGATGCCTTCAGCTCTAATACTAGGAGCAGGCTTAGGGACCCCAGTAACCGTACTCGTCGAACTCGACAAAGAGGTCGACGTGCAACCTAG

Protein

MPAAPASPILVGKTAASSAVVAAPLARSSAGSVGSDGHPASARRSPAPEPAASSSSDSDSDMEVDLAAASSTDGFTLVQKGKKRAAESRAPAAAKISKAANASRPRPPTPVAPPARATPSPRPVAQNKTQTPPPVILQEKAAWDRVSLALQAKKINFISARNLANGIQIKVTTPDDHRALSSYLRKERISFHTYTLQEERELRAVIRGIPKELDADLVKADLLEQGLPETLLKPARRDPKIANYNMVRNDRLTARGGGTVIYYRRALHCVPLDPPALSNIEASVCRISLTGHAPIVIASVYLPPDKIVLSSDIEALLGMGSSVILAGDLNCKHVRWNSHTSTPNGRRLDALVDDLAFDIVAPLTPTHYPLNIAHRPDILDIALLKNVTRRLHSIEVVSELDSDHRPVIMKLGRAPDSVPITRTVVDWHTLGISLAESDPPSLPFSLDSIPSPQDTAEAIDIVTSHITSTLDRSSKQVVAEDFLHRFKLSDDIRELLRAKNASIRAYDSSYSQIGYGSNYAPLVGPSGRLAAFDDDEKAELLADTLQAQCMPSIQSADPVHVELVDSEVERRASLPPLDALPPVTSMEVKDLIKDLRPRKAPGSDGISNRVIKLLPVQLIVMLASIFNATMANCIFPTVWKEADVIGIHKPDKPKNNPTSYRPISLLMSLGKLYERLLYKRLRDFVSSKGILIDEQFGFRANHSCVQQVHRLTEHILVGLNRPKPLYTGALFFDVAKAFDKVWQNGLIFKLFNMGVPDSLVLIIRDFLSNRSFRYRVEGTRSSPRPLTAGVPQGSVLSPLLFSLFINDIPRSPPTQLALFADDTTVYYSSRNKSLIASKLQSAALALGQWFRKWRIDINPAKSTAVLFQRGNSPLISSRIRRRNITPPITLFGQPIPWVRKVKYLGVTLDASMTFRPHIKTVRDRAAFILGRLYPMICKRSKMSLRNKVTLYKTCIRPIMTYASVVFAHAARTHIDTLQSLQSRFCRLAVGAPWFVRNVDLHDDLGLESIQKYMKSASERYFDKAMRHDNRLIVAAADYSPNPDHAGASHRRRPRHVLTDPSDPITFALDAFSSNTRSRLRDPSNRTRRTRQRGRRAT

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

Prefers poly(rC) and poly(rA) as template and activated DNA is not effective.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  RNA-directed DNA polymerase from mobile element jockey

Uniprot

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
V5GNJ2   X1WNI2   J9LC21   X1WZH0   A0A2S2QEE0   K7IN67   J9LFC9   A0A0A9YJ00   A0A224X6U5   A0A224XI99   A0A2J7PVX3   A0A0A9YU04   A0A224XJI0   A0A2H8TF37   A0A2M4CV52   A0A2S2N814   A0A2M4CV42   A0A2M4BD67   A0A2M4BDV6   J9KPF1   A0A2M4BD66   A0A2M4BDA5   A0A2M4BD62   A0A087UCW3   A0A2S2PJG2   A0A069DZL8   A0A3N5Z7I3   A0A2S2NPJ7   A0A224X746   A0A2M4BD83   A0A1Y1KFR3   A0A2S2P7B2   A0A352X8G4   Q07995   A0A2M4BEF4   A0A2M4BEZ9   A0A224XIB0   Q8T9X4   A0A0V0G5B6   A0A2S2P6S3   Q8I7P8   A0A2S2PHL7   A0A023F0I3   J9KSK5   A0A0M4EWX7   A0A1Q3G5J4   A0A232ENU1   P21328  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    20075255    25401762    + More
26334808    30086797    30148503    8387152    25474469    28648823    2463954    3040362    1714378   

EMBL

U07847    AAA17752.1    AB018558    BAA76304.1    AB055391    BAB21761.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    GALX01005299    JAB63167.1    ABLF02008153    ABLF02008462    ABLF02008464    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    ABLF02034467    GGMS01006359    MBY75562.1    ABLF02023911    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    GFTR01008251    JAW08175.1    GFTR01008256    JAW08170.1    NEVH01020940    PNF20481.1    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    GFTR01008257    JAW08169.1    GFXV01000908    MBW12713.1    GGFL01004957    MBW69135.1    GGMR01000676    MBY13295.1    GGFL01005012    MBW69190.1    GGFJ01001858    MBW50999.1    GGFJ01001857    MBW50998.1    ABLF02041767    GGFJ01001844    MBW50985.1    GGFJ01001842    MBW50983.1    GGFJ01001843    MBW50984.1    KK119261    KFM75202.1    GGMR01016905    MBY29524.1    GBGD01000415    JAC88474.1    RPOV01000134    RPJ78669.1    GGMR01006491    MBY19110.1    GFTR01008151    JAW08275.1    GGFJ01001822    MBW50963.1    GEZM01084969    JAV60363.1    GGMR01012676    MBY25295.1    DNOY01000259    HBE18313.1    S59870    AAB26437.2    GGFJ01002256    MBW51397.1    GGFJ01002257    MBW51398.1    GFTR01008246    JAW08180.1    AF456125    AAL57609.1    GECL01003538    JAP02586.1    GGMR01012443    MBY25062.1    AY180919    AAN87272.1    GGMR01016296    MBY28915.1    GBBI01003747    JAC14965.1    ABLF02014118    ABLF02014121    ABLF02054790    CP012527    ALC48130.1    GFDL01000006    JAV35039.1    NNAY01003095    OXU19992.1    M22874    M38643   

Proteomes

UP000053268    UP000007819    UP000002358    UP000235965    UP000054359    UP000092553    + More
UP000215335   

PRIDE

Q93137    Q9XXW0    Q9BPQ0    Q8T9X4    Q8I7P8    P21328    + More

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF07530   PRE_C2HC
PF07727   RVT_2
PF03372   Exo_endo_phos

Interpro

IPR036691   Endo/exonu/phosph_ase_sf        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR000477   RT_dom       
IPR006579   Pre_C2HC_dom       
IPR013103   RVT_2       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
V5GNJ2   X1WNI2   J9LC21   X1WZH0   A0A2S2QEE0   K7IN67   J9LFC9   A0A0A9YJ00   A0A224X6U5   A0A224XI99   A0A2J7PVX3   A0A0A9YU04   A0A224XJI0   A0A2H8TF37   A0A2M4CV52   A0A2S2N814   A0A2M4CV42   A0A2M4BD67   A0A2M4BDV6   J9KPF1   A0A2M4BD66   A0A2M4BDA5   A0A2M4BD62   A0A087UCW3   A0A2S2PJG2   A0A069DZL8   A0A3N5Z7I3   A0A2S2NPJ7   A0A224X746   A0A2M4BD83   A0A1Y1KFR3   A0A2S2P7B2   A0A352X8G4   Q07995   A0A2M4BEF4   A0A2M4BEZ9   A0A224XIB0   Q8T9X4   A0A0V0G5B6   A0A2S2P6S3   Q8I7P8   A0A2S2PHL7   A0A023F0I3   J9KSK5   A0A0M4EWX7   A0A1Q3G5J4   A0A232ENU1   P21328  

KEGG

105841788    no KO assigned | (RefSeq) predicted GPI-anchored protein 58

GO

GO:0003964   GO:0004519  

Length:

1097

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.756619999999999

Exp number, first 60 AAs:

0.01808

Total prob of N-in:

0.00094

outside

1  -  1097

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

21.340928

CSRT

0

Interpretation

Uncertain