Gene

KWMTBOMO03216  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA013635

Annotation

PREDICTED:_FK506-binding_protein_59-like_[Bombyx_mori]

Location

Bomo_Chr6(-):1862129-1879633      View in EpiBrowser

Full name

Peptidylprolyl isomerase      

Location in the cell

Cytoplasmic   Reliability : 3.424

CDS

ATGACTGTGGATCAGGGAGTCGATATTACAAAGAATGGAGATCGTGGAGTCCTAAAACGAATTACCAGGGAAGGAGAGGGTACCGAAACTCCTAACCAAGGATGCCATGTGAGCGTGCATTATGTTGGGACACTACTAGATGGTACCAAGTTTGATTCCAGCAGGGACAGAAACGAACCGTTCGAATTTTGTTTGGGCAAAGATGGTGTAATAGAAGCATGGAAAATTGGTGTGCCTACAATGAAGAAGGGTGAAGTTTGCATTCTGACTTGTGCTCCTGAATATGCCTACGGAGCAAGTGGCAGCCCACCAAAAATCCCTCCAAATGCAACATTGCAGTTTGAGATTGAAATGATTGATTGGAGATTGGAAGATCTTAGTCCTACCAAGAACAAAGGCATACTGCGCCATATCCTCGAGGCTGGTACAGGTCTTGACAGTCCCAACGATGGTGCATTGGTCACAGTTGAACTAGAAGGGAGACTGCAAGGTGATAGCAAAATATTCGATCAGAGAACAGTTACATTTTCACTCGGCGAAGGTACCGAACACAATATATGCGAAGGTATAGAAAGAGCTCTAGAGAAATTTTTGAAAGATGAGAAATCCCGGTTAATTATCCAGCCTAAATATGCCTTTAAGTCCGAAGGGAATTCAGAATTGGGTGTCCCGCCTAATTCTGTCGTAGAATATGTAGTCAAATTGAACAATTTTGAAAGAGCCAAAGACTCTTGGTCAATGGACGGAAATGAAAAACTGGAGCAAGCTAAGATCTTTAAGGAGAAAGGAACAAACTATTTCAAACAGAACAAATTTCAGTTAGCCATCAAAACGTATAAGCGGGCCGTGTCTTTTGTTGATGATATCCCCGAAGATGTTGGTGAAACGGCAGAAAACAAAACAAAAGCTACTGAAATACTCCTGTCAGTTCATCTGAACCTCGCTCTAGTTTACTTGAAGGTGACTCCAATCCACCACTTCGAAGCAAAAGACCATGCGACCAAAGCCCTGAAATTTGACGAGAATAATGTCAAAGGCCTTTTTAGGAGAGGTCAGGCTCTGCTCGGACTGGGAGAAGCAGATTTGGCACTAAAAGACTTCCAAAAGATTATTGAAATTGAACCACAGAACAAAGCAGCAGCCAATCAGATAATAGTTTGTAGAGCTGCAATAGAGAAACAGAAGAGGAAAGAGAAGCAGCTGTACGCGAATATGTTCGACAAGTTTGCGAAGCACGACAACGAGGTAACAGGTGGAGAGACAAAGAGCTAA

Protein

MTVDQGVDITKNGDRGVLKRITREGEGTETPNQGCHVSVHYVGTLLDGTKFDSSRDRNEPFEFCLGKDGVIEAWKIGVPTMKKGEVCILTCAPEYAYGASGSPPKIPPNATLQFEIEMIDWRLEDLSPTKNKGILRHILEAGTGLDSPNDGALVTVELEGRLQGDSKIFDQRTVTFSLGEGTEHNICEGIERALEKFLKDEKSRLIIQPKYAFKSEGNSELGVPPNSVVEYVVKLNNFERAKDSWSMDGNEKLEQAKIFKEKGTNYFKQNKFQLAIKTYKRAVSFVDDIPEDVGETAENKTKATEILLSVHLNLALVYLKVTPIHHFEAKDHATKALKFDENNVKGLFRRGQALLGLGEADLALKDFQKIIEIEPQNKAAANQIIVCRAAIEKQKRKEKQLYANMFDKFAKHDNEVTGGETKS

Catalytic Activity

[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)

Uniprot

Q5CCL2   A0A2H1W3B0   A0A0N1IEI0   A0A194Q3B3   A0A212EQB0   S4NUQ3   + More
A0A2J7R5M3   A0A2J7R5M1   A0A1W4XGW9   A0A1B6LHD6   D2A1L1   A0A2P8ZDT7   A0A1B6KBG5   A0A067R6P2   A0A2A3EKT9   A0A087ZPR8   A0A1Y1N7N3   A0A348G6B5   A0A1Y1N7S5   A0A026WJJ2   E2A2F6   A0A195BL96   A0A1B6E724   A0A3Q0IWR9   A0A1B6D1L5   A0A195FGH6   A0A232FL83   A0A0N7ZCT0   A0A1Q3F545   A0A0L7QUR0   A0A195ECH8   E2B9Y2   Q16ST4   A0A182H9T4   B0X5X1   A0A0P5P192   A0A0N8BQ98   Q16ST5   A0A0N8EC56   A0A0P5HK74   A0A0P5GMQ6   A0A1B6E0J0   A0A0P5N191   A0A0P6HFD6   F4WQ15   A0A0P6DRT3   A0A0P6H1K2   A0A0P5K4G3   A0A1B6DTS3   A0A0P5R3F6   A0A151IM59   A0A0P4ZHJ0   A0A0P5YGM4   A0A0P5D6Q8   A0A0N8AH81   A0A0P5LKR4   A0A0P5SCP2   A0A0P5SUD9   A0A0P5VTX8   A0A0P4WFD0   A0A0P5NPG7   A0A0J7KKS7   A0A1Q3F5B6   A0A0P5BP12   A0A0P6ABK9   A0A0P5PBD7   A0A0P5ZRP4   A0A0P5E2A2   A0A0P5E9K1   A0A0P5YU98   A0A0N8AHQ6   A0A0P5P0X8   A0A0P5TMW1   A0A1W7R9X1   A0A0H3VBG5   A0A0N8E5M7   A0A0P5J3F6   B3MP22   W5NJR1   A0A0P5A8Z0   A0A1W4W8P1   A0A0P5MJY8   A0A0P5IZB1   T1JDQ0   A0A1L8DTU4   A0A0P5HHH6   E9II67   A0A151WKW4   B3N8I9   A0A0P5H0Z3   E9HQG1   A0A154PHL6   A0A0P6DEL5   A0A182P654   A0A093G5Q6   A0A0P6CTC1   A0A2L2Y4R9   B4HWB3   A0A336N7D4  

EC Number

5.2.1.8

Pubmed

26354079    22118469    23622113    18362917    19820115    29403074    + More
24845553    28004739    24508170    30249741    20798317    28648823    17510324    26483478    21719571    25868628    17994087    21282665    21292972    26561354   

EMBL

AB206403    BAD90849.1    ODYU01006064    SOQ47590.1    KQ460542    KPJ14135.1    + More
KQ459579    KPI99499.1    AGBW02013272    OWR43675.1    GAIX01010079    JAA82481.1    NEVH01006991    PNF36128.1    PNF36129.1    GEBQ01016872    GEBQ01005641    JAT23105.1    JAT34336.1    KQ971338    EFA02684.1    PYGN01000086    PSN54651.1    GEBQ01031222    GEBQ01010524    JAT08755.1    JAT29453.1    KK852662    KDR19080.1    KZ288227    PBC31779.1    GEZM01010660    JAV93932.1    FX986031    BBF97988.1    GEZM01010661    JAV93931.1    KK107168    QOIP01000001    EZA56123.1    RLU26884.1    GL436038    EFN72359.1    KQ976441    KYM86424.1    GEDC01003576    JAS33722.1    GEDC01017699    JAS19599.1    KQ981610    KYN39332.1    NNAY01000053    OXU31501.1    GDRN01060797    JAI65304.1    GFDL01012369    JAV22676.1    KQ414731    KOC62363.1    KQ979074    KYN22925.1    GL446610    EFN87500.1    CH477666    EAT37525.1    JXUM01121397    KQ566495    KXJ70084.1    DS232397    EDS41102.1    GDIQ01141580    JAL10146.1    GDIQ01242550    GDIQ01211646    GDIQ01171854    GDIQ01155475    GDIQ01108530    GDIQ01056806    JAK96250.1    EAT37524.1    GDIQ01041220    JAN53517.1    GDIQ01226810    JAK24915.1    GDIQ01245053    JAK06672.1    GEDC01005868    JAS31430.1    GDIQ01150717    JAL01009.1    GDIQ01020225    JAN74512.1    GL888262    EGI63713.1    GDIQ01077640    JAN17097.1    GDIQ01038170    JAN56567.1    GDIQ01190904    GDIQ01096647    JAK60821.1    GEDC01008259    JAS29039.1    GDIQ01106198    JAL45528.1    KQ977063    KYN05959.1    GDIP01212735    JAJ10667.1    GDIP01057997    JAM45718.1    GDIP01162191    JAJ61211.1    GDIP01147689    JAJ75713.1    GDIQ01176953    JAK74772.1    GDIP01141452    JAL62262.1    GDIP01135153    GDIP01120842    LRGB01002140    JAL68561.1    KZS08950.1    GDIP01109897    JAL93817.1    GDRN01060796    JAI65305.1    GDIQ01139624    JAL12102.1    LBMM01006144    KMQ90882.1    GFDL01012326    JAV22719.1    GDIP01186783    JAJ36619.1    GDIP01032845    JAM70870.1    GDIQ01152674    JAK99051.1    GDIP01053165    JAM50550.1    GDIP01148943    JAJ74459.1    GDIP01146288    JAJ77114.1    GDIP01054563    JAM49152.1    GDIP01146289    JAJ77113.1    GDIQ01139625    JAL12101.1    GDIP01125905    JAL77809.1    GFAH01000449    JAV47940.1    KM027245    AJW32183.1    GDIQ01059452    JAN35285.1    GDIQ01211645    JAK40080.1    CH902620    EDV31188.1    AHAT01023565    GDIP01205879    JAJ17523.1    GDIQ01155476    JAK96249.1    GDIQ01213958    JAK37767.1    JH432107    GFDF01004192    JAV09892.1    GDIQ01229591    JAK22134.1    GL763361    EFZ19736.1    KQ983001    KYQ48447.1    CH954177    EDV58412.1    GDIQ01236896    JAK14829.1    GL732720    EFX66021.1    KQ434910    KZC11345.1    GDIQ01087600    JAN07137.1    KL215374    KFV64423.1    GDIQ01087599    JAN07138.1    IAAA01001838    LAA03169.1    CH480818    EDW52308.1    UFQT01003096    SSX34558.1   

Proteomes

UP000053240    UP000053268    UP000007151    UP000235965    UP000192223    UP000007266    + More
UP000245037    UP000027135    UP000242457    UP000005203    UP000053097    UP000279307    UP000000311    UP000078540    UP000079169    UP000078541    UP000215335    UP000053825    UP000078492    UP000008237    UP000008820    UP000069940    UP000249989    UP000002320    UP000007755    UP000078542    UP000076858    UP000036403    UP000007801    UP000018468    UP000192221    UP000075809    UP000008711    UP000000305    UP000076502    UP000075885    UP000053875    UP000001292   

PRIDE

Q5CCL2    A0A087ZPR8   

Pfam

PF00254   FKBP_C        + More
PF13181   TPR_8
PF07719   TPR_2
PF00515   TPR_1
PF13174   TPR_6

Interpro

IPR013026   TPR-contain_dom        + More
IPR011990   TPR-like_helical_dom_sf       
IPR023566   PPIase_FKBP       
IPR031212   FKBP4       
IPR019734   TPR_repeat       
IPR001179   PPIase_FKBP_dom       
IPR013105   TPR_2       
IPR001440   TPR_1       

SUPFAM

SSF48452   SSF48452       

Gene 3D

1.25.40.10    

ProteinModelPortal

Q5CCL2   A0A2H1W3B0   A0A0N1IEI0   A0A194Q3B3   A0A212EQB0   S4NUQ3   + More
A0A2J7R5M3   A0A2J7R5M1   A0A1W4XGW9   A0A1B6LHD6   D2A1L1   A0A2P8ZDT7   A0A1B6KBG5   A0A067R6P2   A0A2A3EKT9   A0A087ZPR8   A0A1Y1N7N3   A0A348G6B5   A0A1Y1N7S5   A0A026WJJ2   E2A2F6   A0A195BL96   A0A1B6E724   A0A3Q0IWR9   A0A1B6D1L5   A0A195FGH6   A0A232FL83   A0A0N7ZCT0   A0A1Q3F545   A0A0L7QUR0   A0A195ECH8   E2B9Y2   Q16ST4   A0A182H9T4   B0X5X1   A0A0P5P192   A0A0N8BQ98   Q16ST5   A0A0N8EC56   A0A0P5HK74   A0A0P5GMQ6   A0A1B6E0J0   A0A0P5N191   A0A0P6HFD6   F4WQ15   A0A0P6DRT3   A0A0P6H1K2   A0A0P5K4G3   A0A1B6DTS3   A0A0P5R3F6   A0A151IM59   A0A0P4ZHJ0   A0A0P5YGM4   A0A0P5D6Q8   A0A0N8AH81   A0A0P5LKR4   A0A0P5SCP2   A0A0P5SUD9   A0A0P5VTX8   A0A0P4WFD0   A0A0P5NPG7   A0A0J7KKS7   A0A1Q3F5B6   A0A0P5BP12   A0A0P6ABK9   A0A0P5PBD7   A0A0P5ZRP4   A0A0P5E2A2   A0A0P5E9K1   A0A0P5YU98   A0A0N8AHQ6   A0A0P5P0X8   A0A0P5TMW1   A0A1W7R9X1   A0A0H3VBG5   A0A0N8E5M7   A0A0P5J3F6   B3MP22   W5NJR1   A0A0P5A8Z0   A0A1W4W8P1   A0A0P5MJY8   A0A0P5IZB1   T1JDQ0   A0A1L8DTU4   A0A0P5HHH6   E9II67   A0A151WKW4   B3N8I9   A0A0P5H0Z3   E9HQG1   A0A154PHL6   A0A0P6DEL5   A0A182P654   A0A093G5Q6   A0A0P6CTC1   A0A2L2Y4R9   B4HWB3   A0A336N7D4  

PDB

1KT1     E-value=1.83737e-95,     Score=891

KEGG

105841234    K09571 FK506-binding protein 4/5 [EC:5.2.1.8] | (RefSeq) FK506-binding protein 59-like

GO

GO:0003755   GO:0005528   GO:0031072   GO:0000413   GO:0005737   GO:0061077   GO:0050908   GO:0016027   GO:0051924   GO:0005515   GO:0006457   GO:0005488   GO:0008013   GO:0007155   GO:0016021   GO:0045211   GO:0006281   GO:0048384  

PANTHER

PTHR10516:SF25   PTHR10516  

Length:

423

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.02085

Exp number, first 60 AAs:

0

Total prob of N-in:

0.01058

outside

1  -  423

 

 

Pi

353.535335

Theta

203.470847

Tajima's D

3.109132

CLR

0.733782

CSRT

0.984150792460377

Interpretation

Uncertain