Gene

KWMTBOMO03172  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA013448

Annotation

SPARC_precursor_[Bombyx_mori]

Location

Bomo_Chr6(+):765333-784414      View in EpiBrowser

Location in the cell

Extracellular   Reliability : 1.49 Nuclear   Reliability : 1.981

CDS

ATGAAGGGTCTTCTTGCGTTGGCCCTCGTGATCGCGGTCATTTGCACCGCCGACGCTAGTCGTATGCGGCGTAGGCACCGCAGGATCCGCACCACGACTACTGAACGTCCAACGTCGGAGCAGCTCGGCCGCGGGGACATCTCGGAGGCTGAACACATCGAGCACGGAATGTCTGAGAGCTTGGACGAGAAGCGATACCATGAGGCAGAAATAGCCAGAGTTAACGACCTTCTCAACGAGGTCTCTAATGAAGAGAATGAAGACGAAGAAATCAACATGGAAGACCCTTGCCTGAAAGTCCACTGCAGCGCAGGACGTGTCTGCGAAATCAACGAACACGGAGACGCCATGTGTAACTGCATCAAGGACTGTCCCTACGAGACAGACTCCAGACGCATGGTGTGCACAAACTTCAACGAAACCTGGCAATCGGATTGCGAAGTATACCGCCAGCGATGCTTATGCCTCGACAACTCTGATCAGTGCCGTGGTCCGCAATACCACCACGTTCAAATCGAGTATTACGGAACGTGCCGAGAAATGCCTGACTGCACTGAAAGCGAGATGTCTGACTTCCCCCGTCGCATGCGGGACTGGCTTTTTAACATCATGCGCGACATGGCTGAACGTAGAGAGCTGACCCCTCATTACCTGAAGATGGAGCGGGAGGCGGAATCAAACCTCACGCGTCGTTGGGCCAATGCCGCTATATGGAAATGGTGCGATCTGGACGCTCAGACCAATGATAGATTCGTGTCCCGTCACGAGCTGTTCCCCATTAGAGCTCCGCTGATGGCCCTAGAGCACTGCATCGCGCCATTCCTGGACCGCTGCGACGCTGACGACGACCACCGCGTCACTCTCGCCGAGTGGGGCAAGTGCCTCGAACTCGACGAGTTGGAAATGGAGGAGCGCTGCGACGATTTCAATGAAAACGCTGAACACTATTTGTAG

Protein

MKGLLALALVIAVICTADASRMRRRHRRIRTTTTERPTSEQLGRGDISEAEHIEHGMSESLDEKRYHEAEIARVNDLLNEVSNEENEDEEINMEDPCLKVHCSAGRVCEINEHGDAMCNCIKDCPYETDSRRMVCTNFNETWQSDCEVYRQRCLCLDNSDQCRGPQYHHVQIEYYGTCREMPDCTESEMSDFPRRMRDWLFNIMRDMAERRELTPHYLKMEREAESNLTRRWANAAIWKWCDLDAQTNDRFVSRHELFPIRAPLMALEHCIAPFLDRCDADDDHRVTLAEWGKCLELDELEMEERCDDFNENAEHYL

Subunit

The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

Similarity

Belongs to the histone H2A family.

Uniprot

Q1HPY3   A0A212EHG6   A0A3S2M3D6   A0A2A4J9Q1   A0A1E1W723   A0A2A4JAH8   + More
A0A2W1BDJ5   I4DLW5   A0A194Q3E9   B2DBL2   S4P872   A0A0N1PJY6   A0A0L7LKZ0   A0A158P1D9   A0A195DUM0   W8BNI5   A0A0L0CSX0   A0A0K8U7D7   A0A0C9Q7B7   A0A034WLR1   T1PF95   A0A1I8MJG7   A0A0A1XGJ2   A0A1A9VPP4   D3TLT3   A0A1B0BUM7   A0A226ES94  

Pubmed

19121390    22118469    28756777    22651552    26354079    18712529    + More
23622113    26227816    21347285    24495485    26108605    25348373    25315136    25830018    20353571   

EMBL

BABH01037341    BABH01037342    BABH01037343    DQ443269    FJ602783    ABF51358.1    + More
ACM24349.1    AGBW02014893    OWR40927.1    RSAL01000053    RVE50042.1    NWSH01002237    PCG68857.1    GDQN01008252    JAT82802.1    PCG68859.1    KZ150187    PZC72451.1    AK402283    BAM18905.1    KQ459579    KPI99539.1    AB264696    BAG30771.1    GAIX01004284    JAA88276.1    KQ459753    KPJ20158.1    JTDY01000787    KOB75876.1    ADTU01006360    KQ980390    KYN16249.1    GAMC01003895    JAC02661.1    JRES01000062    KNC34504.1    GDHF01029730    GDHF01026115    JAI22584.1    JAI26199.1    GBYB01010053    JAG79820.1    GAKP01003671    GAKP01003670    JAC55282.1    KA647359    AFP61988.1    GBXI01009357    GBXI01004231    JAD04935.1    JAD10061.1    EZ422385    ADD18661.1    JXJN01020807    LNIX01000002    OXA60379.1   

Proteomes

UP000005204    UP000007151    UP000283053    UP000218220    UP000053268    UP000053240    + More
UP000037510    UP000005205    UP000078492    UP000037069    UP000095301    UP000078200    UP000092460    UP000198287   

PRIDE

Q1HPY3   

Pfam

PF09289   FOLN        + More
PF10591   SPARC_Ca_bdg
PF00125   Histone
PF16211   Histone_H2A_C
PF07648   Kazal_2

Interpro

IPR011992   EF-hand-dom_pair        + More
IPR001999   Osteonectin_CS       
IPR019577   SPARC/Testican_Ca-bd-dom       
IPR015369   Follistatin/Osteonectin_EGF       
IPR018247   EF_Hand_1_Ca_BS       
IPR036058   Kazal_dom_sf       
IPR032454   Histone_H2A_C       
IPR007125   Histone_H2A/H2B/H3       
IPR009072   Histone-fold       
IPR032458   Histone_H2A_CS       
IPR002119   Histone_H2A       
IPR003645   Fol_N       
IPR002350   Kazal_dom       

SUPFAM

SSF47473   SSF47473        + More
SSF100895   SSF100895       
SSF47113   SSF47113       

Gene 3D

1.10.20.10    

CDD

cd00074  H2A

ProteinModelPortal

Q1HPY3   A0A212EHG6   A0A3S2M3D6   A0A2A4J9Q1   A0A1E1W723   A0A2A4JAH8   + More
A0A2W1BDJ5   I4DLW5   A0A194Q3E9   B2DBL2   S4P872   A0A0N1PJY6   A0A0L7LKZ0   A0A158P1D9   A0A195DUM0   W8BNI5   A0A0L0CSX0   A0A0K8U7D7   A0A0C9Q7B7   A0A034WLR1   T1PF95   A0A1I8MJG7   A0A0A1XGJ2   A0A1A9VPP4   D3TLT3   A0A1B0BUM7   A0A226ES94  

PDB

1NUB     E-value=7.0314e-28,     Score=307

KEGG

732958    no KO assigned | (RefSeq) SPARC; secreted protein, acidic, cysteine-rich (osteonectin)

GO

GO:0005509   GO:0005615   GO:0062023   GO:0005518   GO:0046982   GO:0003677   GO:0000786   GO:0005634   GO:0016021   GO:0005515   GO:0005578   GO:0007165   GO:0045211   GO:0006281   GO:0048384  

Subcellular location

Chromosome  
Nucleus  

SignalP

Position:   1 - 19,         Likelihood:  0.997035

 

 

Length:

317

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

6.44418

Exp number, first 60 AAs:

6.44056

Total prob of N-in:

0.13330

outside

1  -  317

 

 

Pi

159.238553

Theta

166.095786

Tajima's D

-0.487295

CLR

159.735149

CSRT

0.239638018099095

Interpretation

Uncertain