Gene

KWMTBOMO03168

Pre Gene Modal

BGIBMGA013446

Annotation

PREDICTED:_uncharacterized_protein_LOC106134809_[Amyelois_transitella]

Location

Bomo_Chr6(+):727663-731565      View in EpiBrowser

Full name

MICOS complex subunit MIC60      

Alternative Name

Mitofilin

Location in the cell

Cytoplasmic   Reliability : 1.275 Mitochondrial   Reliability : 1.012 Nuclear   Reliability : 1.401

CDS

ATGGTCCGCGATGGGATACGTCCCTTTGACTTCCTTCGTCAGTTCGATCCTCGTAACGAGCTGGTGATTCCTCGGGCCGACTTCTACCGAGGACTGGCTTCTGCAGGACTTTCACTGACGCCACTCGAAATGGATACGCTAATGGAAGTTTTCAGCGCCCCGGGTCGACGTAGATACGTGGAGTACGCTAGGTTCTCGTCCACCGTGGGCGAGGCTCTCACACAAGAAGGCCTAGAACGCGCACCGCTGCTGGTGCCAGTACCCCACCTCCCCACAGTAGACACGCCCCTCAACTACCTGAACTTCGAGGAACGGAATATTGTGTCCGGAGCTCTTGCCAAACTTGCAAAATATCCTGATCAGTTGTCTAATATAATCGAGGTGTTCCAGGATATAGATAGGGTACGTTGTGGAACCGTGCCGCGGGTATCAGCCGAGCGTGCTCTGTGCCAACGTGGTCTTCTGGCGCTTTTGTCATCGAGAGAAAGAGACACGCTCTACAAATGCTTCGGATACAGGCGAGGATGCGGTGACGAGGTAAATTATCGTGCACTGTGCAACGCTCTGGATGTACTGTACGCCACTACTAATGCTCAAAAATGTTAA

Protein

MVRDGIRPFDFLRQFDPRNELVIPRADFYRGLASAGLSLTPLEMDTLMEVFSAPGRRRYVEYARFSSTVGEALTQEGLERAPLLVPVPHLPTVDTPLNYLNFEERNIVSGALAKLAKYPDQLSNIIEVFQDIDRVRCGTVPRVSAERALCQRGLLALLSSRERDTLYKCFGYRRGCGDEVNYRALCNALDVLYATTNAQKC

Description

Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.

Subunit

Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.

Similarity

Belongs to the MICOS complex subunit Mic60 family.
Belongs to the G-protein coupled receptor 1 family.

Uniprot

H9JV83   A0A2A4JF51   A0A2W1BRS6   A0A212EHH3   A0A2H1X3K4   A0A3S2P1L2   + More
A0A437ARA9   A0A194Q1X5   A0A0N1IH31   A0A0L7LNE7   A0A0T6B5X0   D6W947   N6U0C9   U4UF71   N6TXK3   A0A1W4WLJ6   A0A1Y1LDK1   A0A2P8YA30   A0A1S4FJD7   E0W159   A0A0L7RJB4   A0A1B6LR61   A0A182QSD8   A0A2A3EFG4   A0A0L0BYC0   A0A1B6MF68   B0WNC0   A0A087ZWP7   A0A026WHW5   A0A0J7KWR4   A0A1Q3FT57   A0A1B6K8A9   A0A154P491   A0A182TPE4   A0A2C9GR75   Q7QBY7   A0A182V3N9   A0A1B6DIZ4   A0A182VQA2   A0A1B6E3V0   A0A1I8PT42   A0A034VHG8   A0A084VJQ0   A0A1A9YS41   A0A1B0C3I7   A0A1B0FM66   A0A1B6E8U0   A0A1A9VKK1   A0A2R7VZZ3   A0A182XIC1   A0A195BFD8   A0A158NRF0   A0A182PA37   A0A3L8DJY8   A0A0K8W749   A0A0K8W8K1   A0A1A9ZG80   W8AHL7   A0A0K8V3S6   A0A182LFF7   A0A182S5M9   A0A1I8M395   A0A182MLL2   A0A0A1WR13   A0A151XF24   A0A182Y788   B4JIA6   A0A336KCV6   B4M0T2   A0A3B0KRI1   A0A336LCA6   A0A195FJH1   B4NKF0   A0A3B0KHD4   A0A1A9W6F7   E2AGH4   K7J532   A0A232ENR8   B4KA60   Q297Q1   B4G2V1   W5JW03   A0A182N4N9   B4PQG5   A0A182JYI6   B4R175   A0A182F6G5   B4HFQ9   B3P429   A0A1W4UR15   B3LXA1   A0A0M9A5F1   A0A0B4K6G7   Q9VFT7   A0A151JBN9   A0A182RCX1   A0A151IFQ2  

Pubmed

19121390    28756777    22118469    26354079    26227816    18362917    + More
19820115    23537049    28004739    29403074    20566863    26108605    24508170    12364791    14747013    17210077    25348373    24438588    21347285    30249741    24495485    20966253    25315136    25830018    25244985    17994087    20798317    20075255    28648823    15632085    20920257    23761445    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356   

EMBL

BABH01037347    BABH01037348    NWSH01001644    PCG70591.1    KZ149979    PZC75857.1    + More
AGBW02014893    OWR40921.1    ODYU01013136    SOQ59826.1    RSAL01000053    RVE50039.1    RSAL01003121    RVE40335.1    KQ459579    KPI99546.1    KQ459753    KPJ20165.1    JTDY01000546    KOB76721.1    LJIG01009616    KRT82724.1    KQ971312    EEZ98210.1    APGK01047442    APGK01047443    KB741081    ENN74041.1    KB632295    ERL91682.1    ENN74040.1    GEZM01058719    JAV71703.1    PYGN01000762    PSN41117.1    DS235866    EEB19365.1    KQ414580    KOC71062.1    GEBQ01013898    JAT26079.1    AXCN02000058    KZ288259    PBC30477.1    JRES01001160    KNC24966.1    GEBQ01005413    JAT34564.1    DS232010    EDS31574.1    KK107238    EZA54679.1    LBMM01002535    KMQ94694.1    GFDL01004317    JAV30728.1    GECU01000008    JAT07699.1    KQ434812    KZC06769.1    APCN01000432    AAAB01008859    EAA07680.5    GEDC01011627    JAS25671.1    GEDC01004696    JAS32602.1    GAKP01017939    JAC41013.1    ATLV01013846    KE524905    KFB38194.1    JXJN01024960    CCAG010009081    GEDC01002993    JAS34305.1    KK854205    PTY13064.1    KQ976504    KYM82924.1    ADTU01023858    ADTU01023859    QOIP01000007    RLU20681.1    GDHF01005358    JAI46956.1    GDHF01004848    JAI47466.1    GAMC01018597    GAMC01018595    JAB87960.1    GDHF01018798    JAI33516.1    AXCM01005074    GBXI01012798    JAD01494.1    KQ982205    KYQ58992.1    CH916369    EDV92987.1    UFQS01000220    UFQT01000220    SSX01558.1    SSX21938.1    CH940650    EDW67374.1    OUUW01000013    SPP87851.1    UFQS01003048    UFQT01003048    SSX15109.1    SSX34489.1    KQ981522    KYN40553.1    CH964272    EDW84080.1    SPP87850.1    GL439310    EFN67507.1    AAZX01000327    AAZX01000328    AAZX01014618    NNAY01003101    OXU19977.1    CH933806    EDW16735.1    CM000070    EAL28154.1    CH479179    EDW24146.1    ADMH02000291    ETN67104.1    CM000160    EDW97261.1    CM000364    EDX13052.1    CH480815    EDW42294.1    CH954181    EDV49203.1    CH902617    EDV41701.2    KQ435729    KOX77600.1    AE014297    AFH06405.1    AY058348    AAF54962.2    AAL13577.1    KQ979122    KYN22536.1    KQ977771    KYM99975.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000283053    UP000053268    UP000053240    + More
UP000037510    UP000007266    UP000019118    UP000030742    UP000192223    UP000245037    UP000009046    UP000053825    UP000075886    UP000242457    UP000037069    UP000002320    UP000005203    UP000053097    UP000036403    UP000076502    UP000075902    UP000075840    UP000007062    UP000075903    UP000075920    UP000095300    UP000030765    UP000092443    UP000092460    UP000092444    UP000078200    UP000076407    UP000078540    UP000005205    UP000075885    UP000279307    UP000092445    UP000075882    UP000075901    UP000095301    UP000075883    UP000075809    UP000076408    UP000001070    UP000008792    UP000268350    UP000078541    UP000007798    UP000091820    UP000000311    UP000002358    UP000215335    UP000009192    UP000001819    UP000008744    UP000000673    UP000075884    UP000002282    UP000075881    UP000000304    UP000069272    UP000001292    UP000008711    UP000192221    UP000007801    UP000053105    UP000000803    UP000078492    UP000075900    UP000078542   

PRIDE

H9JV83    Q9VFT7   

Pfam

PF00085   Thioredoxin        + More
PF01918   Alba
PF09731   Mitofilin
PF00474   SSF
PF00001   7tm_1

Interpro

IPR002048   EF_hand_dom        + More
IPR011992   EF-hand-dom_pair       
IPR036249   Thioredoxin-like_sf       
IPR013766   Thioredoxin_domain       
IPR036882   Alba-like_dom_sf       
IPR002775   DNA/RNA-bd_Alba-like       
IPR019133   Mt-IM_prot_Mitofilin       
IPR018247   EF_Hand_1_Ca_BS       
IPR001734   Na/solute_symporter       
IPR038377   Na/Glc_symporter_sf       
IPR013087   Znf_C2H2_type       
IPR017452   GPCR_Rhodpsn_7TM       
IPR000276   GPCR_Rhodpsn       

SUPFAM

SSF47473   SSF47473        + More
SSF52833   SSF52833       
SSF82704   SSF82704       

Gene 3D

3.30.110.20     1.20.1730.10    

ProteinModelPortal

H9JV83   A0A2A4JF51   A0A2W1BRS6   A0A212EHH3   A0A2H1X3K4   A0A3S2P1L2   + More
A0A437ARA9   A0A194Q1X5   A0A0N1IH31   A0A0L7LNE7   A0A0T6B5X0   D6W947   N6U0C9   U4UF71   N6TXK3   A0A1W4WLJ6   A0A1Y1LDK1   A0A2P8YA30   A0A1S4FJD7   E0W159   A0A0L7RJB4   A0A1B6LR61   A0A182QSD8   A0A2A3EFG4   A0A0L0BYC0   A0A1B6MF68   B0WNC0   A0A087ZWP7   A0A026WHW5   A0A0J7KWR4   A0A1Q3FT57   A0A1B6K8A9   A0A154P491   A0A182TPE4   A0A2C9GR75   Q7QBY7   A0A182V3N9   A0A1B6DIZ4   A0A182VQA2   A0A1B6E3V0   A0A1I8PT42   A0A034VHG8   A0A084VJQ0   A0A1A9YS41   A0A1B0C3I7   A0A1B0FM66   A0A1B6E8U0   A0A1A9VKK1   A0A2R7VZZ3   A0A182XIC1   A0A195BFD8   A0A158NRF0   A0A182PA37   A0A3L8DJY8   A0A0K8W749   A0A0K8W8K1   A0A1A9ZG80   W8AHL7   A0A0K8V3S6   A0A182LFF7   A0A182S5M9   A0A1I8M395   A0A182MLL2   A0A0A1WR13   A0A151XF24   A0A182Y788   B4JIA6   A0A336KCV6   B4M0T2   A0A3B0KRI1   A0A336LCA6   A0A195FJH1   B4NKF0   A0A3B0KHD4   A0A1A9W6F7   E2AGH4   K7J532   A0A232ENR8   B4KA60   Q297Q1   B4G2V1   W5JW03   A0A182N4N9   B4PQG5   A0A182JYI6   B4R175   A0A182F6G5   B4HFQ9   B3P429   A0A1W4UR15   B3LXA1   A0A0M9A5F1   A0A0B4K6G7   Q9VFT7   A0A151JBN9   A0A182RCX1   A0A151IFQ2  

KEGG

101740137    no KO assigned | (RefSeq) uncharacterized LOC101740137

GO

GO:0005509   GO:0016021   GO:0005743   GO:0045454   GO:0003676   GO:0022857   GO:0004930  

PANTHER

PTHR15415  

Subcellular location

Mitochondrion inner membrane  

Length:

201

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01982

Exp number, first 60 AAs:

0.01892

Total prob of N-in:

0.08135

outside

1  -  201

 

 

Pi

172.281094

Theta

170.418327

Tajima's D

0.019405

CLR

0.151791

CSRT

0.370031498425079

Interpretation

Uncertain