Gene

KWMTBOMO03167

Pre Gene Modal

BGIBMGA013446

Annotation

PREDICTED:_uncharacterized_protein_LOC106134809_[Amyelois_transitella]

Location

Bomo_Chr6(+):716053-722106      View in EpiBrowser

Full name

MICOS complex subunit MIC60      

Alternative Name

Mitofilin

Location in the cell

Cytoplasmic   Reliability : 1.762 Mitochondrial   Reliability : 1.161 Nuclear   Reliability : 1.09

CDS

ATGGTAGCAAAAAATGACGGTCGTATAACATTCGCTCATTTCGCTCGAATCCTAAATTTCATTGGAGTCCTAGTTTCGCCGGAGGACTTCAATTTGCTGGTGCGTCGGTTCATCAAAGATTCTTACACGCTCGACTACGTGGAATTCCTTAAAGCTGTTGAAGCTGTGCAAAAGGAGGGCATCCAAGGCCTTGGACCGGCTTACAACAACCCCAATGCCATAATAGATACGACACTGCCCAAGTTGCCACGTCCCGAAATTGAAGCAGGATTATCGACAGCGCCTCTAGGAGCTAATGATGTCTTCCATCCAGTTCTCGACCCGCCAAAGCCGCCACGGCAGCTGGTGGAACTCATGCTGAGGGTGCAAGAGTTTGTGCTACAGAGGAGGATTAGAGTTTCCGAATTTTTCAGGGACTACGACCCCTTGAACAGCGGTCGCATTTCCGCGCTACAGTTTCGTCGCGCACTGGACGCCATGGGGCTCAGCACTATCATGTCACCTGCGGAACAACTCTGCGTGTTGAGGCACTACGTCGACCCCAACGATAGAGAGAAAGTATGCTGGAGGACCTTCGAAGATGATTGTGATCAGGTGTTCACAGTTAAAGAATTAGAAAAGCATCCAAACGTAGTGCCCGGTGCCGCAGCCGAAGTAGTGAGGAGTTTGCCAGCAGTTGGAGCTACTAGCGGTGACAGTCCTAGCGATGTGGACGCTGCGCTCCTCCGAGTGAGAGCTGCCTGCACGGAGAGGGCCATCGACTTAAGACCGGCCTTCTCTGAACACGACCAGTTAGTAACTTAA

Protein

MVAKNDGRITFAHFARILNFIGVLVSPEDFNLLVRRFIKDSYTLDYVEFLKAVEAVQKEGIQGLGPAYNNPNAIIDTTLPKLPRPEIEAGLSTAPLGANDVFHPVLDPPKPPRQLVELMLRVQEFVLQRRIRVSEFFRDYDPLNSGRISALQFRRALDAMGLSTIMSPAEQLCVLRHYVDPNDREKVCWRTFEDDCDQVFTVKELEKHPNVVPGAAAEVVRSLPAVGATSGDSPSDVDAALLRVRAACTERAIDLRPAFSEHDQLVT

Description

Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.

Subunit

Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.

Similarity

Belongs to the G-protein coupled receptor 1 family.
Belongs to the MICOS complex subunit Mic60 family.

Uniprot

H9JV83   A0A3S2P1L2   A0A2A4JFJ7   A0A212FCN9   A0A2W1BRS6   A0A194Q1X5   + More
A0A0N1IH31   A0A087ZWP7   D6W947   A0A1W4WLJ6   A0A2A3EFG4   A0A154P491   N6TXK3   E2AGH4   F4W3V4   A0A026WHW5   A0A3L8DJY8   A0A195FJH1   A0A151XF24   A0A151IFQ2   A0A151JBN9   U4UF71   E0W159   A0A195BFD8   A0A0M9A5F1   A0A1B6K8A9   A0A1B6E8U0   A0A310SD23   A0A158NRF0   A0A1B6MF68   A0A232ENS2   A0A1Y1LDK1   A0A336LCA6   N6U0C9   A0A0A1WR13   A0A0K8W8K1   A0A0K8W749   A0A0K8V3S6   A0A0L7RJB4   A0A1I8N9R4   A0A336KCV6   B4R175   B4HFQ9   Q9VFT7   A0A0B4K6G7   A0A1W4UR15   A0A034VES4   A0A1A9VKK1   Q16YT3   A0A1S4FJD7   A0A1A9ZG80   B4NKF0   A0A1B0FM66   B4PQG5   B3P429   A0A0L0BYC0   B0WNC0   A0A1A9W6F7   W8AHL7   Q297Q1   A0A1A9YS41   B4G2V1   A0A1B0C3I7   A0A1Q3FT57   A0A1J1J204   B3LXA1   B4KA60   K7J532   A0A3B0KHD4   B4M0T2   B4JIA6   A0A1I8PT42   A0A369S3X6   A0A0M4ERW1   A0A3B0KRI1   B3RW52   A0A1B6HCQ8   A0A182PA37   A0A182RCX1   A0A3M7PZR7   A0A182Y788   A0A182LFF7   K1PW59   A0A182INR9   A0A2C9GR75   A0A1B6LR61   C3ZWG8   A0A182XIC1   Q7QBY7   A0A182TPE4   A0A084VJQ0   A0A182MLL2   A0A0R3WZI4   A0A068Y896  

Pubmed

19121390    22118469    28756777    26354079    18362917    19820115    + More
23537049    20798317    21719571    24508170    30249741    20566863    21347285    28648823    28004739    25830018    25315136    17994087    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    25348373    17510324    17550304    26108605    24495485    15632085    20075255    30042472    18719581    30375419    25244985    20966253    22992520    18563158    12364791    14747013    17210077    24438588    23485966   

EMBL

BABH01037347    BABH01037348    RSAL01000053    RVE50039.1    NWSH01001644    PCG70589.1    + More
AGBW02009155    OWR51515.1    KZ149979    PZC75857.1    KQ459579    KPI99546.1    KQ459753    KPJ20165.1    KQ971312    EEZ98210.1    KZ288259    PBC30477.1    KQ434812    KZC06769.1    APGK01047442    APGK01047443    KB741081    ENN74040.1    GL439310    EFN67507.1    GL887480    EGI71118.1    EGI71119.1    KK107238    EZA54679.1    QOIP01000007    RLU20681.1    KQ981522    KYN40553.1    KQ982205    KYQ58992.1    KQ977771    KYM99975.1    KQ979122    KYN22536.1    KB632295    ERL91682.1    DS235866    EEB19365.1    KQ976504    KYM82924.1    KQ435729    KOX77600.1    GECU01000008    JAT07699.1    GEDC01002993    JAS34305.1    KQ762959    OAD55194.1    ADTU01023858    ADTU01023859    GEBQ01005413    JAT34564.1    NNAY01003101    OXU19976.1    GEZM01058719    JAV71703.1    UFQS01003048    UFQT01003048    SSX15109.1    SSX34489.1    ENN74041.1    GBXI01012798    JAD01494.1    GDHF01004848    JAI47466.1    GDHF01005358    JAI46956.1    GDHF01018798    JAI33516.1    KQ414580    KOC71062.1    UFQS01000220    UFQT01000220    SSX01558.1    SSX21938.1    CM000364    EDX13052.1    CH480815    EDW42294.1    AE014297    AY058348    AAF54962.2    AAL13577.1    AFH06405.1    GAKP01017938    JAC41014.1    CH477509    EAT39799.1    CH964272    EDW84080.1    CCAG010009081    CM000160    EDW97261.1    CH954181    EDV49203.1    JRES01001160    KNC24966.1    DS232010    EDS31574.1    GAMC01018597    GAMC01018595    JAB87960.1    CM000070    EAL28154.1    CH479179    EDW24146.1    JXJN01024960    GFDL01004317    JAV30728.1    CVRI01000065    CRL05796.1    CH902617    EDV41701.2    CH933806    EDW16735.1    AAZX01000327    AAZX01000328    AAZX01014618    OUUW01000013    SPP87850.1    CH940650    EDW67374.1    CH916369    EDV92987.1    NOWV01000075    RDD41439.1    CP012526    ALC47347.1    SPP87851.1    DS985244    EDV26117.1    GECU01035231    JAS72475.1    REGN01008103    RNA04454.1    JH818302    EKC23244.1    APCN01000432    GEBQ01013898    JAT26079.1    GG666699    EEN43097.1    AAAB01008859    EAA07680.5    ATLV01013846    KE524905    KFB38194.1    AXCM01005074    UYWX01020295    VDM30362.1    LN902843    CDS39451.1   

Proteomes

UP000005204    UP000283053    UP000218220    UP000007151    UP000053268    UP000053240    + More
UP000005203    UP000007266    UP000192223    UP000242457    UP000076502    UP000019118    UP000000311    UP000007755    UP000053097    UP000279307    UP000078541    UP000075809    UP000078542    UP000078492    UP000030742    UP000009046    UP000078540    UP000053105    UP000005205    UP000215335    UP000053825    UP000095301    UP000000304    UP000001292    UP000000803    UP000192221    UP000078200    UP000008820    UP000092445    UP000007798    UP000092444    UP000002282    UP000008711    UP000037069    UP000002320    UP000091820    UP000001819    UP000092443    UP000008744    UP000092460    UP000183832    UP000007801    UP000009192    UP000002358    UP000268350    UP000008792    UP000001070    UP000095300    UP000253843    UP000092553    UP000009022    UP000075885    UP000075900    UP000276133    UP000076408    UP000075882    UP000005408    UP000075880    UP000075840    UP000001554    UP000076407    UP000007062    UP000075902    UP000030765    UP000075883    UP000046396    UP000274429    UP000017246   

PRIDE

H9JV83    Q9VFT7   

Pfam

PF00001   7tm_1        + More
PF00160   Pro_isomerase
PF00474   SSF
PF00085   Thioredoxin
PF01918   Alba
PF09731   Mitofilin
PF13833   EF-hand_8

Interpro

IPR002048   EF_hand_dom        + More
IPR011992   EF-hand-dom_pair       
IPR017452   GPCR_Rhodpsn_7TM       
IPR000276   GPCR_Rhodpsn       
IPR002130   Cyclophilin-type_PPIase_dom       
IPR029000   Cyclophilin-like_dom_sf       
IPR001734   Na/solute_symporter       
IPR038377   Na/Glc_symporter_sf       
IPR002775   DNA/RNA-bd_Alba-like       
IPR019133   Mt-IM_prot_Mitofilin       
IPR036882   Alba-like_dom_sf       
IPR013766   Thioredoxin_domain       
IPR036249   Thioredoxin-like_sf       
IPR013087   Znf_C2H2_type       
IPR000644   CBS_dom       

SUPFAM

SSF47473   SSF47473        + More
SSF50891   SSF50891       
SSF82704   SSF82704       
SSF52833   SSF52833       

Gene 3D

2.40.100.10     1.20.1730.10     3.30.110.20    

ProteinModelPortal

H9JV83   A0A3S2P1L2   A0A2A4JFJ7   A0A212FCN9   A0A2W1BRS6   A0A194Q1X5   + More
A0A0N1IH31   A0A087ZWP7   D6W947   A0A1W4WLJ6   A0A2A3EFG4   A0A154P491   N6TXK3   E2AGH4   F4W3V4   A0A026WHW5   A0A3L8DJY8   A0A195FJH1   A0A151XF24   A0A151IFQ2   A0A151JBN9   U4UF71   E0W159   A0A195BFD8   A0A0M9A5F1   A0A1B6K8A9   A0A1B6E8U0   A0A310SD23   A0A158NRF0   A0A1B6MF68   A0A232ENS2   A0A1Y1LDK1   A0A336LCA6   N6U0C9   A0A0A1WR13   A0A0K8W8K1   A0A0K8W749   A0A0K8V3S6   A0A0L7RJB4   A0A1I8N9R4   A0A336KCV6   B4R175   B4HFQ9   Q9VFT7   A0A0B4K6G7   A0A1W4UR15   A0A034VES4   A0A1A9VKK1   Q16YT3   A0A1S4FJD7   A0A1A9ZG80   B4NKF0   A0A1B0FM66   B4PQG5   B3P429   A0A0L0BYC0   B0WNC0   A0A1A9W6F7   W8AHL7   Q297Q1   A0A1A9YS41   B4G2V1   A0A1B0C3I7   A0A1Q3FT57   A0A1J1J204   B3LXA1   B4KA60   K7J532   A0A3B0KHD4   B4M0T2   B4JIA6   A0A1I8PT42   A0A369S3X6   A0A0M4ERW1   A0A3B0KRI1   B3RW52   A0A1B6HCQ8   A0A182PA37   A0A182RCX1   A0A3M7PZR7   A0A182Y788   A0A182LFF7   K1PW59   A0A182INR9   A0A2C9GR75   A0A1B6LR61   C3ZWG8   A0A182XIC1   Q7QBY7   A0A182TPE4   A0A084VJQ0   A0A182MLL2   A0A0R3WZI4   A0A068Y896  

KEGG

101740137    no KO assigned | (RefSeq) uncharacterized LOC101740137

GO

GO:0005509   GO:0004930   GO:0016021   GO:0003755   GO:0022857   GO:0005743   GO:0003676   GO:0045454   GO:0006810   GO:0016020   GO:0006355   GO:0007179   GO:0005515   GO:0045211   GO:0006281   GO:0048384  

PANTHER

PTHR15415  

Subcellular location

Mitochondrion inner membrane  

Length:

267

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

3.18148

Exp number, first 60 AAs:

3.17949

Total prob of N-in:

0.25362

outside

1  -  267

 

 

Pi

195.299336

Theta

198.495173

Tajima's D

0.136241

CLR

0

CSRT

0.402129893505325

Interpretation

Uncertain