Gene

KWMTBOMO03164

Pre Gene Modal

BGIBMGA013466

Annotation

Vesicular_acetylcholine_transporter_[Papilio_xuthus]

Location

Bomo_Chr6(-):571917-608942      View in EpiBrowser

Full name

Vesicular acetylcholine transporter      

Location in the cell

PlasmaMembrane   Reliability : 4.643

CDS

ATGGCGGAGGGACCACAGACGATATGGCAGAGGATCGACAATTCCATGATTCCAATCGTCAACTTGGAAGTGAGGGAAGTAAGGGAGATATTATGGGAGAAAATCAAAGAGCCGACCTCCCAGAGAAAAATCATCCTCGTTATAGTATCTATAGCCTTGTTGCTAGACAACATGTTGTATATGGTCATAGTGCCAATAATCCCAGACTATCTGAGATACATTGGCGCATGGGGTGAGGCAGCTTACGACCACGTGGTTACTTTGCCGCCAATCAAAGAAGGGAACAGAACAGTGATACCGACGAAGATCATTCCTGGTTCTCATGAGGGGCAAGATTCGGCTACTGGAGTTCTGTTTGCATCAAAAGCTATAGTTCAGCTGATGATTAATCCCTTTTCCGGTGCTTTAATCGATCGTATCGGCTACGATATTCCCATGATGATAGGACTGATCATTATGTTCCTGTCGACATCGATCTTCGCTTGCGGTAGAAGTTATAGCATGTTGTTCTTTGCTAGGAGTCTCCAAGGGGTCGGATCGGCGTTTGCTGATACATCAGGCTTGGCTATGATCGCTGACAGATTTACCGAAGAATCCGAGCGCTCTAAAGCACTAGGCATAGCACTGGCATTTATTAGTTTTGGAAGCCTGGTCGCTCCACCATTTGGCGGTGCTTTATATCAATTTGCGGGCAAGGAAGTGCCATTTCTTATTTTGGCATTGATATCCTTAATGGATGGATTCATGTTATTACTCGTCATGAAGCCAATAAAGACTCAGATCAAAGAGGCGAATGAACCAAAACCAGCTGGAACTCCAATTTGGAAGCTCTTGATTGATCCTTACATCGCAGTTTGCGCTGGAGCTTTAATGATGTCGAATGTAGCGCTTGCATTCCTAGAGCCCACGATTTCATCTTGGATGGAAGACAATTTGACTAAAGATAATTGGAAAATAGGCATGATATGGCTACCGGCTTTCTTTCCTCATGTTCTGGGTGTGATCATAACCGTCAAGATGGCAAAGAAGTACCCTCAACACCAATGGTTGATGGCTGCTGGTGGGTTGGCTCTGGAAGGTTTATGTTGTTTCATCATACCTTTCGCGAGTTCGTATAAGATGTTGATGATTCCTATTTGCGGTATATGCTTCGGGATTGCCTTGATCGACACAGCTTTGCTGCCAACTCTTGGATACTTGGTTGATGTTCGTTATGTATCTGTCTACGGAAGTATTTATGCCATTGCTGACATATCATACTCCTTCGCTTATGCTGTAGGACCCATCATCGCTGGAGAAGTCGTCGAGGCTATTGGATTCACTGCTTTGAACCTGCTAATTGCGTTCAGTAATCTTCTTTATGCACCAGTGCTGATGTACCTTCGGCATATTTATGACTTCAAGCCATTTGAGAACGAAGCCAATATTTTGATGGCTGATCCACCAGATAAAGAATACCAGACTTACACCATGCAAGACCAGAAGCCGATTAATGGAGACTATAAAAATCACTTGGAGTACAATAGTAGTGCCGGTCAAGCTACTCAGGAATCAAATGTGGATGCTGGGAATTATTCTTACGACCAGACGTATCAAGGAGGAAGTTATAGCCAAGGCTATGAACAGCAAGGATACCATCAAGAATATCAGCAGGCGGAGTACAACCAACCGAGGCAGTTACCGGCTCAGCCACAGACGGATTATGAATACGAAGCATAG

Protein

MAEGPQTIWQRIDNSMIPIVNLEVREVREILWEKIKEPTSQRKIILVIVSIALLLDNMLYMVIVPIIPDYLRYIGAWGEAAYDHVVTLPPIKEGNRTVIPTKIIPGSHEGQDSATGVLFASKAIVQLMINPFSGALIDRIGYDIPMMIGLIIMFLSTSIFACGRSYSMLFFARSLQGVGSAFADTSGLAMIADRFTEESERSKALGIALAFISFGSLVAPPFGGALYQFAGKEVPFLILALISLMDGFMLLLVMKPIKTQIKEANEPKPAGTPIWKLLIDPYIAVCAGALMMSNVALAFLEPTISSWMEDNLTKDNWKIGMIWLPAFFPHVLGVIITVKMAKKYPQHQWLMAAGGLALEGLCCFIIPFASSYKMLMIPICGICFGIALIDTALLPTLGYLVDVRYVSVYGSIYAIADISYSFAYAVGPIIAGEVVEAIGFTALNLLIAFSNLLYAPVLMYLRHIYDFKPFENEANILMADPPDKEYQTYTMQDQKPINGDYKNHLEYNSSAGQATQESNVDAGNYSYDQTYQGGSYSQGYEQQGYHQEYQQAEYNQPRQLPAQPQTDYEYEA

Similarity

Belongs to the major facilitator superfamily. Vesicular transporter family.

Keywords

Complete proteome   Glycoprotein   Membrane   Neurotransmitter transport   Reference proteome   Transmembrane   Transmembrane helix   Transport  

Feature

chain  Vesicular acetylcholine transporter

Uniprot

H9JVA3   A0A212FCP6   A0A0N0PEL3   A0A194Q1Y0   A0A2H1VZT8   A0A2A4J2I7   + More
A0A0G3VG09   A0A0L7LF40   D6W971   A0A2J7Q7C1   A0A2P8YA25   A0A182Y784   A0A067RCA1   A0A1Y1KTX3   A0A182RYG7   A0A084W1L3   A0A182J1B3   A0A182N4P3   A0A182M1V9   T1I654   A0A1J1J2W2   A0A182W2X5   A0A0T6BDE1   U5EX12   A0A182PA41   A0A182UE01   A0A2R7WRG2   A0A182UGY9   Q16SX3   Q7PR83   A0A182XIB7   A0A182T7R7   E0W161   A0A182G771   A0A0L0CQ39   A0A182VCH4   E2AGG8   A0A182F6G2   W5JVM7   F4WB43   A0A1S3D026   A0A232EMV3   K7J534   A0A195FJG4   A0A1A9XZF5   A0A1B0BUL9   A0A1A9VIY3   E2C7G8   A0A1A9ZL63   A0A1B0GET2   A0A310SPT4   A0A1A9W5V3   E9IS27   A0A336MP64   A0A0L7RJK5   A0A195BFI5   A0A087ZWQ0   A0A158NRC4   A0A1W4X2P3   A0A1I8NUP2   A0A151JBS7   A0A2A3EGY5   A0A1I8M3G4   A0A026WF51   V9I6X8   A0A182KBJ2   B0W363   A0A0J7L6J2   A0A0C9RXM3   A0A182QP81   W8C1Q4   A0A0Q9WUM0   A0A154P5Y7   A0A1W4UPF5   A0A3B0K361   A0A182HTA2   A0A0Q9X4V4   A0A0M5J8U6   B4K1S6   B4MBC3   I5ANM2   A0A0P8XY20   A0A2H8TD87   D2NUG3   O17444   A0A2S2NLL7   J9JXZ7   A0A2S2QJZ0   E9G3N1   B7QD10   A0A0P5XI13   A0A0P6G6T8   A0A1D2N677   A0A0P6C1V8   A0A2I6QBP8   A0A226CYU2   A0A0P5B8W8   A0A0P5BAW4   A0A0P5IXP8   A0A0P5KY64  

Pubmed

19121390    22118469    26354079    26227816    18362917    19820115    + More
29403074    25244985    24845553    28004739    24438588    17510324    12364791    14747013    17210077    20566863    26483478    26108605    20798317    20920257    23761445    21719571    28648823    20075255    21282665    21347285    25315136    24508170    30249741    24495485    17994087    15632085    9446576    10731132    12537572    21292972    27289101    29236686   

EMBL

BABH01037362    AB871890    BAO23492.1    AGBW02009155    OWR51511.1    KQ459753    + More
KPJ20169.1    KQ459579    KPI99551.1    ODYU01005161    SOQ45754.1    NWSH01003475    PCG66221.1    KP657649    AKL78874.1    JTDY01001459    KOB73816.1    KQ971312    EEZ98455.2    NEVH01017443    PNF24483.1    PYGN01000762    PSN41105.1    KK852798    KDR16361.1    GEZM01075679    JAV64018.1    ATLV01019381    KE525269    KFB44107.1    AXCM01000067    ACPB03008308    CVRI01000065    CRL05790.1    LJIG01001596    KRT85344.1    GANO01001162    JAB58709.1    KK855354    PTY22144.1    CH477664    EAT37546.1    AAAB01008859    EAA07682.6    DS235866    EEB19367.1    JXUM01046136    KQ561464    KXJ78489.1    JRES01000062    KNC34475.1    GL439310    EFN67501.1    ADMH02000344    ETN66889.1    GL888056    EGI68598.1    NNAY01003307    OXU19647.1    AAZX01000328    KQ981522    KYN40548.1    JXJN01020792    GL453369    EFN76155.1    CCAG010012585    KQ760497    OAD60097.1    GL765283    EFZ16652.1    UFQS01001326    UFQT01001326    SSX10359.1    SSX30047.1    KQ414580    KOC71055.1    KQ976504    KYM82930.1    ADTU01023865    KQ979122    KYN22540.1    KZ288259    PBC30479.1    KK107238    QOIP01000007    EZA54672.1    RLU20763.1    JR035965    JR035966    JR035967    JR035968    AEY56830.1    AEY56831.1    AEY56832.1    AEY56833.1    DS231831    EDS31206.1    LBMM01000504    KMQ98193.1    GBYB01013930    JAG83697.1    AXCN02000061    GAMC01006914    JAB99641.1    CH964272    KRF99855.1    KQ434812    KZC06764.1    OUUW01000005    SPP80389.1    APCN01000427    CH933806    KRG02377.1    CP012526    ALC45474.1    CH917801    EDW04624.1    CH940656    EDW58394.1    CM000070    EIM52557.1    CH902617    KPU79602.1    GFXV01000249    MBW12054.1    BT120106    ADB13439.1    AF030197    AE014297    GGMR01005464    MBY18083.1    ABLF02025153    ABLF02025155    GGMS01008647    MBY77850.1    GL732531    EFX85953.1    ABJB011139869    DS910653    EEC16732.1    GDIP01071795    LRGB01001574    JAM31920.1    KZS11615.1    GDIQ01048214    JAN46523.1    LJIJ01000187    ODN00757.1    GDIP01010637    JAM93078.1    KY809750    AUN27676.1    LNIX01000063    OXA37206.1    GDIP01187824    JAJ35578.1    GDIP01187823    JAJ35579.1    GDIQ01207956    JAK43769.1    GDIQ01203454    JAK48271.1   

Proteomes

UP000005204    UP000007151    UP000053240    UP000053268    UP000218220    UP000037510    + More
UP000007266    UP000235965    UP000245037    UP000076408    UP000027135    UP000075900    UP000030765    UP000075880    UP000075884    UP000075883    UP000015103    UP000183832    UP000075920    UP000075885    UP000075902    UP000008820    UP000007062    UP000076407    UP000075901    UP000009046    UP000069940    UP000249989    UP000037069    UP000075903    UP000000311    UP000069272    UP000000673    UP000007755    UP000079169    UP000215335    UP000002358    UP000078541    UP000092443    UP000092460    UP000078200    UP000008237    UP000092445    UP000092444    UP000091820    UP000053825    UP000078540    UP000005203    UP000005205    UP000192223    UP000095300    UP000078492    UP000242457    UP000095301    UP000053097    UP000279307    UP000075881    UP000002320    UP000036403    UP000075886    UP000007798    UP000076502    UP000192221    UP000268350    UP000075840    UP000009192    UP000092553    UP000001070    UP000008792    UP000001819    UP000007801    UP000000803    UP000007819    UP000000305    UP000001555    UP000076858    UP000094527    UP000198287   

PRIDE

H9JVA3    D2NUG3    O17444   

Pfam

PF07690   MFS_1        + More
PF00755   Carn_acyltransf

Interpro

IPR020846   MFS_dom        + More
IPR036259   MFS_trans_sf       
IPR011701   MFS       
IPR004734   Multidrug-R       
IPR000542   Carn_acyl_trans       
IPR039551   Cho/carn_acyl_trans       
IPR042231   Cho/carn_acyl_trans_2       
IPR042232   Cho/carn_acyl_trans_1       

SUPFAM

SSF103473   SSF103473       

Gene 3D

3.30.559.40     3.30.559.70    

CDD

cd06174  MFS

ProteinModelPortal

H9JVA3   A0A212FCP6   A0A0N0PEL3   A0A194Q1Y0   A0A2H1VZT8   A0A2A4J2I7   + More
A0A0G3VG09   A0A0L7LF40   D6W971   A0A2J7Q7C1   A0A2P8YA25   A0A182Y784   A0A067RCA1   A0A1Y1KTX3   A0A182RYG7   A0A084W1L3   A0A182J1B3   A0A182N4P3   A0A182M1V9   T1I654   A0A1J1J2W2   A0A182W2X5   A0A0T6BDE1   U5EX12   A0A182PA41   A0A182UE01   A0A2R7WRG2   A0A182UGY9   Q16SX3   Q7PR83   A0A182XIB7   A0A182T7R7   E0W161   A0A182G771   A0A0L0CQ39   A0A182VCH4   E2AGG8   A0A182F6G2   W5JVM7   F4WB43   A0A1S3D026   A0A232EMV3   K7J534   A0A195FJG4   A0A1A9XZF5   A0A1B0BUL9   A0A1A9VIY3   E2C7G8   A0A1A9ZL63   A0A1B0GET2   A0A310SPT4   A0A1A9W5V3   E9IS27   A0A336MP64   A0A0L7RJK5   A0A195BFI5   A0A087ZWQ0   A0A158NRC4   A0A1W4X2P3   A0A1I8NUP2   A0A151JBS7   A0A2A3EGY5   A0A1I8M3G4   A0A026WF51   V9I6X8   A0A182KBJ2   B0W363   A0A0J7L6J2   A0A0C9RXM3   A0A182QP81   W8C1Q4   A0A0Q9WUM0   A0A154P5Y7   A0A1W4UPF5   A0A3B0K361   A0A182HTA2   A0A0Q9X4V4   A0A0M5J8U6   B4K1S6   B4MBC3   I5ANM2   A0A0P8XY20   A0A2H8TD87   D2NUG3   O17444   A0A2S2NLL7   J9JXZ7   A0A2S2QJZ0   E9G3N1   B7QD10   A0A0P5XI13   A0A0P6G6T8   A0A1D2N677   A0A0P6C1V8   A0A2I6QBP8   A0A226CYU2   A0A0P5B8W8   A0A0P5BAW4   A0A0P5IXP8   A0A0P5KY64  

PDB

6GV1     E-value=0.010301,     Score=93

KEGG

101742935    K14636 MFS transporter, DHA1 family, solute carrier family 18 (vesicular acetylcholine transporter),

GO

GO:0015238   GO:0016021   GO:0005277   GO:0043195   GO:0030121   GO:0030122   GO:0016746   GO:0055085   GO:0006836   GO:0015893   GO:0006355   GO:0007179   GO:0005515   GO:0045211   GO:0006281   GO:0048384   GO:0042910  

PANTHER

PTHR22589  

Subcellular location

Membrane  

Length:

572

Number of predicted TMHs:

10

Exp number of AAs in TMHs:

218.44818

Exp number, first 60 AAs:

16.40849

Total prob of N-in:

0.99698

POSSIBLE N-term signal

sequence

inside

1  -  44

TMhelix

45  -  67

outside

68  -  139

TMhelix

140  -  162

inside

163  -  203

TMhelix

204  -  226

outside

227  -  235

TMhelix

236  -  253

inside

254  -  281

TMhelix

282  -  304

outside

305  -  318

TMhelix

319  -  336

inside

337  -  348

TMhelix

349  -  371

outside

372  -  374

TMhelix

375  -  397

inside

398  -  408

TMhelix

409  -  431

outside

432  -  435

TMhelix

436  -  458

inside

459  -  572

 

 

Pi

240.662422

Theta

176.219059

Tajima's D

1.198695

CLR

0.667057

CSRT

0.716014199290036

Interpretation

Uncertain