Gene

KWMTBOMO03083  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA005759

Annotation

PREDICTED:_histone_deacetylase_6_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr5(+):17678904-17689062      View in EpiBrowser

Location in the cell

Extracellular   Reliability : 2.394

CDS

ATGGAGGTGAGTCCGGCGTGCTACGCGGTCCTGCTGCACGCGCTGCAGTCGGTGACGTCGCGCGTGTGCGTGGTGCTGGAGGGCGGCTACTGCCTGACGTCGCTGGCCGAGGGGGCCGCCCTCACGCTGCGGACGCTGCTGGGCGACGCGCCCCCCAAACTGGAGCCCCCCACGCCCCCCTGCGACTCAATCCGCGACACGATACTGGACTGCATATACGCGCACAGACAGTACTGGAGCTGCTACAGCTACCAGCCCGCGCGGGGGGACCGCCACGAGGTGCTCGTGCGGTGGCGGGGCGACGAGACGCGCCCGTCGCGCTTCGCCACCCGGGACTGCTACCCGACGCAGGACGAGCCCACCCGCCGGGCCCTCGAGGACAGACTCGACCACTTGCGAGCGGTGACGGATCTGACGTCACCGACCCACGCGGTCGGTTACGTGTACGACGAGGCGATGCTGAAGCACAGGAACGTGGTCGAACCAGGCCACGTCGAAAGTCCGGAGCGTATCATGAGGATCCACGAGCGACATCGGGACTTCGGTCTGCTGGAGAGGCTGCACCGGCTGCCCGGCCGCGCCGCCTCCGACCAGGAGATACTGAGCGTGCACTCCGACAAATATTTGGACAGGTTAAAGGAGCTGGCGTCGACGAAGTTGCGGGACCTGAATAACCAGAAGGAGGAGTACGACTCTGTGTACTTTCACCCGGAGTCGCTGTCCAGCGCTGCTGTGGCGGCCGGCTGCGTGCTGCAGGCGGTGGAGGCGGTGGTGTCGGGGCAGTGCGGCGCCGCCGCGTGCGTGGTGCGCCCGCCCGGACACCACGCCGCCCGCGCCGCGCCCGCCGGCTTCTGTCTGCTCAACAACGCCGCGCTGGCCGCCCGCGCCGCCCACCGCGTGCTGCTGCTCGACTGGGACGTGCACCACGGGAACGGCACGCAGGCGCTCACCTACACCGACGACCAGATACTGTACATATCGATACATCGTTACGACCACGGCTCGTTCTTCCCGCACTCGAAGGACGCGGACTACACGGCCGTGGGCACGGGGCGGGGCGAGGGCTACAATATCAACATACCTTGGAATAAGCGCGGCATGGGTGACGCGGAGTACATGGCCGCCTTCACCCAGGTCGTGCTGCCGATAGCTCACGAGTATAATCCGGATCTGGTGATCGTGTCAGCGGGGTTCGATGCCTGCGTGGGAGACCCACTGGGAGGTTGTAAAGTAACTCCGGAGTGCTACGGCCGCATGACGCAGCTGCTGCGAGGGCTCGCCGGAGGTCGGGTGGTGCTCTGTCTAGAGGGCGGCTACAACACCACCGCCATCTCCTACGCCATGACCATGTGCACCAAGGCCCTGCTGGGAGACCCCATACTGCACCACTACGAACCGAGGACCGCCTGCCACTGGTCCGCCGTCGAGACCATAAACAACGTCATCAGCACGCACAAGAAGTACTGGAAGAGCCTCGCCTTCCAACTCGCTCTGCCGTCTGAGGACGTCCTCCAGCGGCCGGCGCCGTCGCGAGGCCTGTCCGACCTGTCCGACGCGCTGTCGTCTTCATACGAGGACACCAAGTCGGACTCCAAGAGCGGCAGTCAACTGGACACTTCCCTGGAGCACAACATGGCCAACCTCAGTCTGAACAAATGTGGAGACGGCGTGCACTGCGGCACTGACGACGAGGACGAGGCCGGCGACACCGCGTCCAATTCTAATCCGGAATCGACTGGCAATACCAAGAGTTTAGTGGATTACTTGTCGGAGAACATGCAGGCGCTCGTGGAGGGCGAGATGTTCGCCGTGGTGCCGCTGGGCTGGTGCCCGCACCTGGAGGCGCTGTACGCCATCCCCGCCGGGGTCCGCTTCCAGCAGGGACTCCAGTGTGTCGACTGCGAACACACCCTGGAGAACTGGGTGTGTCTGCACTGCTACATTACGGCGTGCGCGCGCGGCGTGAACGCTCACATGCAGGCGCACTGGGCGGCGAGCGGGCACGCGCTGGTGCTGTCCCTGCGCGACCTGTCCGTGTGGTGCTGCGCGTGCGACGCCTACGTGGACCACCCGCTGCTCTACGACGCCAAGAACAACGCGCACCGCTGCAAGTTCGGCGAGGACATGCCGTGGTGCTACGCCGCAGACGCCGTAGAGATGCACTAG

Protein

MEVSPACYAVLLHALQSVTSRVCVVLEGGYCLTSLAEGAALTLRTLLGDAPPKLEPPTPPCDSIRDTILDCIYAHRQYWSCYSYQPARGDRHEVLVRWRGDETRPSRFATRDCYPTQDEPTRRALEDRLDHLRAVTDLTSPTHAVGYVYDEAMLKHRNVVEPGHVESPERIMRIHERHRDFGLLERLHRLPGRAASDQEILSVHSDKYLDRLKELASTKLRDLNNQKEEYDSVYFHPESLSSAAVAAGCVLQAVEAVVSGQCGAAACVVRPPGHHAARAAPAGFCLLNNAALAARAAHRVLLLDWDVHHGNGTQALTYTDDQILYISIHRYDHGSFFPHSKDADYTAVGTGRGEGYNINIPWNKRGMGDAEYMAAFTQVVLPIAHEYNPDLVIVSAGFDACVGDPLGGCKVTPECYGRMTQLLRGLAGGRVVLCLEGGYNTTAISYAMTMCTKALLGDPILHHYEPRTACHWSAVETINNVISTHKKYWKSLAFQLALPSEDVLQRPAPSRGLSDLSDALSSSYEDTKSDSKSGSQLDTSLEHNMANLSLNKCGDGVHCGTDDEDEAGDTASNSNPESTGNTKSLVDYLSENMQALVEGEMFAVVPLGWCPHLEALYAIPAGVRFQQGLQCVDCEHTLENWVCLHCYITACARGVNAHMQAHWAASGHALVLSLRDLSVWCCACDAYVDHPLLYDAKNNAHRCKFGEDMPWCYAADAVEMH

Uniprot

H9J8B7   A0A2A4K9K1   A0A212EKT9   A0A0N1IFV9   A0A232EY44   A0A2H1V5Y8   + More
A0A194PNW8   A0A2A3E8Y9   A0A026WEW9   A0A0C9RAW9   A0A0C9QXQ2   A0A0C9PVI5   W8AUN6   A0A1B0CKE5   A0A034VDF4   A0A151IE82   A0A034VCF9   A0A1L8DWX0   A0A1L8DWX2   A0A1L8DX38   A0A0K8UNE7   A0A1I8N1Y0   T1PCM9   A0A146M156   A0A146M6T1   A0A1I8QAY2   A0A1I8QAT3   A0A2R7VR43   A0A1Q3FFU5   A0A0L0CDD2   A0A1Q3FFT5   Q17MD0   U5EY31   A0A182HDK7   B0WYC3   A0A182TVE2   A0A182QX80   A0A2C9GN10   A0A182IAB3   A0A2C9GN14   A0A2C9GN13   A0A182XEE8   A0A182N087   A0A182ITD2   A0A182P7U1   A0A151JWF8   A0A182UT34   A0A182M582   A0A1B6LQS3   A0A1A9Z1Q0   A0A1A9X8T7   A0A1B0AX61   A0A084WPJ0   A0A224X835   Q7PS30   F5HJG6   A0A1S4G969   A0A1A9VRM0   A0A1S4G9B5   A0A087ZVG5   A0A1B0FAE5   E9G8H1   A0A1B6EJ36   A0A182R9J4   A0A310SEE4   A0A0N8BYZ8   A0A0P5I5E0   A0A0P4VUQ3   A0A182W4L4   A0A0V0G4V9   A0A1W4VG25   A0A1W4V3A6   A0A069DZQ4   A0A0P5PX88   A0A154PR89   B3MR87   T1I028   A0A0P5UXL6   A0A0N8ABH1   C5I7C2   C5I7C3   A0A164Q769   A0A0P5BQB2   C5I7C4   A0A0P5ZEG0   A0A0N8DD01   A0A0P5Z8Z0   A0A0N8DCI9   C5I7E6   C5I7H8   Q86NK9   M9NGF7   C5I7Q8   C5I7G2   A0A0N8ANU9   A0A182K760   C5I798   I1V507   C5I7I0   C5I7E8  

Pubmed

19121390    22118469    26354079    28648823    24508170    24495485    + More
25348373    25315136    26823975    26108605    17510324    26483478    24438588    12364791    21292972    27129103    26334808    17994087    19349642    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356   

EMBL

BABH01027412    BABH01027413    BABH01027414    NWSH01000041    PCG80342.1    AGBW02014213    + More
OWR42102.1    KQ460968    KPJ10234.1    NNAY01001682    OXU23235.1    ODYU01000661    SOQ35822.1    KQ459597    KPI95126.1    KZ288345    PBC27659.1    KK107238    EZA54635.1    GBYB01005460    JAG75227.1    GBYB01005457    JAG75224.1    GBYB01005458    JAG75225.1    GAMC01013995    JAB92560.1    AJWK01016114    AJWK01016115    AJWK01016116    AJWK01016117    AJWK01016118    GAKP01019157    JAC39795.1    KQ977890    KYM98970.1    GAKP01019160    JAC39792.1    GFDF01003123    JAV10961.1    GFDF01003124    JAV10960.1    GFDF01003122    JAV10962.1    GDHF01024112    JAI28202.1    KA646522    AFP61151.1    GDHC01006033    JAQ12596.1    GDHC01003166    JAQ15463.1    KK854011    PTY09301.1    GFDL01008627    JAV26418.1    JRES01000557    KNC30256.1    GFDL01008626    JAV26419.1    CH477207    EAT47819.1    GANO01000573    JAB59298.1    JXUM01129864    JXUM01129865    JXUM01129866    KQ567502    KXJ69403.1    DS232187    EDS37000.1    AXCN02001229    APCN01001139    KQ981653    KYN38619.1    AXCM01000566    GEBQ01013954    JAT26023.1    JXJN01005088    ATLV01025080    KE525369    KFB52134.1    GFTR01007921    JAW08505.1    AAAB01008846    EAA06256.6    EGK96427.1    CCAG010015202    GL732535    EFX83972.1    GECZ01031831    JAS37938.1    KQ762207    OAD56055.1    GDIQ01131075    JAL20651.1    GDIQ01224445    JAK27280.1    GDKW01002034    JAI54561.1    GECL01003078    JAP03046.1    GBGD01000235    JAC88654.1    GDIQ01132433    JAL19293.1    KQ435007    KZC13630.1    CH902622    EDV34292.2    ACPB03019368    GDIP01108030    JAL95684.1    GDIP01163769    JAJ59633.1    FJ764838    ACN94063.1    ACN94066.1    LRGB01002451    KZS07492.1    GDIP01181816    JAJ41586.1    ACN94067.1    GDIP01045840    JAM57875.1    GDIP01045839    JAM57876.1    GDIP01047136    JAM56579.1    GDIP01047135    JAM56580.1    FJ764841    FJ764842    ACN94087.1    ACN94095.1    FJ764845    ACN94119.1    AE014298    BT004866    FJ764836    FJ764837    FJ764839    FJ764840    FJ764844    FJ764846    FJ764847    FJ764848    FJ764849    FJ764850    FJ764851    FJ764853    FJ764854    FJ764856    FJ764858    AAF48443.2    AAO45222.1    ACN94047.1    ACN94055.1    ACN94071.1    ACN94079.1    ACN94111.1    ACN94127.1    ACN94135.1    ACN94143.1    ACN94151.1    ACN94159.1    ACN94167.1    ACN94183.1    ACN94191.1    ACN94209.1    ACN94223.1    AFH07394.1    FJ764855    ACN94199.1    FJ764843    ACN94103.1    GDIQ01257467    JAJ94257.1    FJ764835    FJ764852    FJ764857    ACN94041.1    ACN94175.1    ACN94215.1    JQ663530    AFI26268.1    ACN94123.1    ACN94091.1    ACN94099.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053240    UP000215335    UP000053268    + More
UP000242457    UP000053097    UP000092461    UP000078542    UP000095301    UP000095300    UP000037069    UP000008820    UP000069940    UP000249989    UP000002320    UP000075902    UP000075886    UP000075840    UP000076407    UP000075884    UP000075880    UP000075885    UP000078541    UP000075903    UP000075883    UP000092445    UP000092443    UP000092460    UP000030765    UP000007062    UP000078200    UP000005203    UP000092444    UP000000305    UP000075900    UP000075920    UP000192221    UP000076502    UP000007801    UP000015103    UP000076858    UP000000803    UP000075881   

PRIDE

H9J8B7    Q86NK9   

Pfam

PF00850   Hist_deacetyl        + More
PF02148   zf-UBP
PF06479   Ribonuc_2-5A
PF00069   Pkinase

Interpro

IPR013083   Znf_RING/FYVE/PHD        + More
IPR000286   His_deacetylse       
IPR023696   Ureohydrolase_dom_sf       
IPR037138   His_deacetylse_dom_sf       
IPR023801   His_deacetylse_dom       
IPR001607   Znf_UBP       
IPR018997   PUB_domain       
IPR010513   KEN_dom       
IPR011009   Kinase-like_dom_sf       
IPR008271   Ser/Thr_kinase_AS       
IPR000719   Prot_kinase_dom       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR011047   Quinoprotein_ADH-like_supfam       
IPR038357   KEN_sf       
IPR018391   PQQ_beta_propeller_repeat       

SUPFAM

SSF52768   SSF52768        + More
SSF56112   SSF56112       
SSF50998   SSF50998       

Gene 3D

3.30.40.10     3.40.800.20     1.20.1440.180     2.130.10.10    

ProteinModelPortal

H9J8B7   A0A2A4K9K1   A0A212EKT9   A0A0N1IFV9   A0A232EY44   A0A2H1V5Y8   + More
A0A194PNW8   A0A2A3E8Y9   A0A026WEW9   A0A0C9RAW9   A0A0C9QXQ2   A0A0C9PVI5   W8AUN6   A0A1B0CKE5   A0A034VDF4   A0A151IE82   A0A034VCF9   A0A1L8DWX0   A0A1L8DWX2   A0A1L8DX38   A0A0K8UNE7   A0A1I8N1Y0   T1PCM9   A0A146M156   A0A146M6T1   A0A1I8QAY2   A0A1I8QAT3   A0A2R7VR43   A0A1Q3FFU5   A0A0L0CDD2   A0A1Q3FFT5   Q17MD0   U5EY31   A0A182HDK7   B0WYC3   A0A182TVE2   A0A182QX80   A0A2C9GN10   A0A182IAB3   A0A2C9GN14   A0A2C9GN13   A0A182XEE8   A0A182N087   A0A182ITD2   A0A182P7U1   A0A151JWF8   A0A182UT34   A0A182M582   A0A1B6LQS3   A0A1A9Z1Q0   A0A1A9X8T7   A0A1B0AX61   A0A084WPJ0   A0A224X835   Q7PS30   F5HJG6   A0A1S4G969   A0A1A9VRM0   A0A1S4G9B5   A0A087ZVG5   A0A1B0FAE5   E9G8H1   A0A1B6EJ36   A0A182R9J4   A0A310SEE4   A0A0N8BYZ8   A0A0P5I5E0   A0A0P4VUQ3   A0A182W4L4   A0A0V0G4V9   A0A1W4VG25   A0A1W4V3A6   A0A069DZQ4   A0A0P5PX88   A0A154PR89   B3MR87   T1I028   A0A0P5UXL6   A0A0N8ABH1   C5I7C2   C5I7C3   A0A164Q769   A0A0P5BQB2   C5I7C4   A0A0P5ZEG0   A0A0N8DD01   A0A0P5Z8Z0   A0A0N8DCI9   C5I7E6   C5I7H8   Q86NK9   M9NGF7   C5I7Q8   C5I7G2   A0A0N8ANU9   A0A182K760   C5I798   I1V507   C5I7I0   C5I7E8  

PDB

5G0I     E-value=1.04265e-95,     Score=896

KEGG

101741658    K11407 histone deacetylase 6 [EC:3.5.1.98] | (RefSeq) histone deacetylase 6

GO

GO:0016787   GO:0008270   GO:0004672   GO:0005524   GO:0004540   GO:0006397   GO:0006355   GO:0007269   GO:0005737   GO:0016575   GO:0019213   GO:0098793   GO:0032041   GO:0004407   GO:0005759   GO:0006627   GO:0006508   GO:0008237   GO:0016020   GO:0051103   GO:0003677   GO:0006281   GO:0048384  

Length:

721

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.19811

Exp number, first 60 AAs:

0.16963

Total prob of N-in:

0.00820

outside

1  -  721

 

 

Pi

371.733484

Theta

196.479818

Tajima's D

2.982098

CLR

0.570962

CSRT

0.975951202439878

Interpretation

Uncertain